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Cadogan E 's Articles

[29969258] Correction to Discovery of Novel 3-Quinoline Carboxamides as Potent, Selective, and Orally Bioavailable Inhibitors of Ataxia Telangiectasia Mutated (ATM) Kinase.

Degorce Sébastien L , Barlaam Bernard , Cadogan Elaine , Dishington Allan , Ducray Richard , Glossop Steven C , Hassall Lorraine A , Lach Franck , Lau Alan , McGuire Thomas M , Nowak Thorsten , Ouvry Gilles , Pike Kurt G , Thomason Andrew G ,

[29941481] The combination of the PARP inhibitor olaparib and the Wee1 inhibitor AZD1775 as a new therapeutic option for small cell lung cancer.

Lallo Alice , Frese Kristopher K , Morrow Christopher , Szczepaniak Sloane Robert , Gulati Sakshi , Schenk Maximilian W , Trapani Francesca , Simms Nicole , Galvin Melanie , Brown Stewart , Hodgkinson Cassandra L , Priest Lynsey , Hughes Adina M , Lai Zhongwu , Cadogan Elaine B , Khandelwal Garima , Simpson Kathryn L , Miller Crispin , Blackhall Fiona H , O'Connor Mark J , Dive Caroline ,

[29769307] Orally Bioavailable and Blood-Brain Barrier-Penetrating ATM Inhibitor (AZ32) Radiosensitizes Intracranial Gliomas in Mice.

Karlin Jeremy , Allen Jasmine , Ahmad Syed F , Hughes Gareth , Sheridan Victoria , Odedra Rajesh , Farrington Paul , Cadogan Elaine B , Riches Lucy C , Garcia-Trinidad Antonio , Thomason Andrew G , Patel Bhavika , Vincent Jennifer , Lau Alan , Pike Kurt G , Hunt Thomas A , Sule Amrita , Valerie Nicholas C K , Biddlestone-Thorpe Laura , Kahn Jenna , Beckta Jason M , Mukhopadhyay Nitai , Barlaam Bernard , Degorce Sebastien L , Kettle Jason , Colclough Nicola , Wilson Joanne , Smith Aaron , Barrett Ian P , Zheng Li , Zhang Tianwei , Wang Yingchun , Chen Kan , Pass Martin , Durant Stephen T , Valerie Kristoffer ,

[29683659] The Identification of Potent, Selective, and Orally Available Inhibitors of Ataxia Telangiectasia Mutated (ATM) Kinase: The Discovery of AZD0156 (8-{6-[3-(Dimethylamino)propoxy]pyridin-3-yl}-3-methyl-1-(tetrahydro-2 H-pyran-4-yl)-1,3-dihydro-2 H-imidazo[4,5- c]quinolin-2-one).

Pike Kurt G , Barlaam Bernard , Cadogan Elaine , Campbell Andrew , Chen Yingxue , Colclough Nicola , Davies Nichola L , de-Almeida Camila , Degorce Sebastien L , Didelot Myriam , Dishington Allan , Ducray Richard , Durant Stephen T , Hassall Lorraine A , Holmes Jane , Hughes Gareth D , MacFaul Philip A , Mulholland Keith R , McGuire Thomas M , Ouvry Gilles , Pass Martin , Robb Graeme , Stratton Natalie , Wang Zhenhua , Wilson Joanne , Zhai Baochang , Zhao Kang , Al-Huniti Nidal ,

[29635390] RAD51 foci as a functional biomarker of homologous recombination repair and PARP inhibitor resistance in germline BRCA-mutated breast cancer.

Cruz C , Castroviejo-Bermejo M , Gutiérrez-Enríquez S , Llop-Guevara A , Ibrahim Y H , Gris-Oliver A , Bonache S , Morancho B , Bruna A , Rueda O M , Lai Z , Polanska U M , Jones G N , Kristel P , de Bustos L , Guzman M , Rodríguez O , Grueso J , Montalban G , Caratú G , Mancuso F , Fasani R , Jiménez J , Howat W J , Dougherty B , Vivancos A , Nuciforo P , Serres-Créixams X , Rubio I T , Oaknin A , Cadogan E , Barrett J C , Caldas C , Baselga J , Saura C , Cortés J , Arribas J , Jonkers J , Díez O , O'Connor M J , Balmaña J , Serra V ,

[29340025] The novel ATM inhibitor (AZ31) enhances antitumor activity in patient derived xenografts that are resistant to irinotecan monotherapy.

Greene Justin , Nguyen Anna , Bagby Stacey M , Jones Gemma N , Tai W M , Quackenbush Kevin S , Schreiber Anna , Messersmith Wells A , Devaraj Kalpana M , Blatchford Patrick , Eckhardt S Gail , Cadogan Elaine B , Hughes Gareth D , Smith Aaron , Pitts Todd M , Arcaroli John J ,

[28145510] Pharmacologic ATM but not ATR kinase inhibition abrogates p21-dependent G1 arrest and promotes gastrointestinal syndrome after total body irradiation.

Vendetti Frank P , Leibowitz Brian J , Barnes Jennifer , Schamus Sandy , Kiesel Brian F , Abberbock Shira , Conrads Thomas , Clump David Andy , Cadogan Elaine , O'Connor Mark J , Yu Jian , Beumer Jan H , Bakkenist Christopher J ,

[27625305] Targeting the kinase activities of ATR and ATM exhibits antitumoral activity in mouse models of MLL-rearranged AML.

Morgado-Palacin Isabel , Day Amanda , Murga Matilde , Lafarga Vanesa , Anton Marta Elena , Tubbs Anthony , Chen Hua Tang , Ergan Aysegul , Anderson Rhonda , Bhandoola Avinash , Pike Kurt G , Barlaam Bernard , Cadogan Elaine , Wang Xi , Pierce Andrew J , Hubbard Chad , Armstrong Scott A , Nussenzweig André , Fernandez-Capetillo Oscar ,

[27259031] Discovery of Novel 3-Quinoline Carboxamides as Potent, Selective, and Orally Bioavailable Inhibitors of Ataxia Telangiectasia Mutated (ATM) Kinase.

Degorce Sébastien L , Barlaam Bernard , Cadogan Elaine , Dishington Allan , Ducray Richard , Glossop Steven C , Hassall Lorraine A , Lach Franck , Lau Alan , McGuire Thomas M , Nowak Thorsten , Ouvry Gilles , Pike Kurt G , Thomason Andrew G ,

[26865565] Aurora kinase inhibitor nanoparticles target tumors with favorable therapeutic index in vivo.

Ashton Susan , Song Young Ho , Nolan Jim , Cadogan Elaine , Murray Jim , Odedra Rajesh , Foster John , Hall Peter A , Low Susan , Taylor Paula , Ellston Rebecca , Polanska Urszula M , Wilson Joanne , Howes Colin , Smith Aaron , Goodwin Richard J A , Swales John G , Strittmatter Nicole , Takáts Zoltán , Nilsson Anna , Andren Per , Trueman Dawn , Walker Mike , Reimer Corinne L , Troiano Greg , Parsons Donald , De Witt David , Ashford Marianne , Hrkach Jeff , Zale Stephen , Jewsbury Philip J , Barry Simon T ,

[25367918] Down Syndrome Disintegrative Disorder: New-Onset Autistic Regression, Dementia, and Insomnia in Older Children and Adolescents With Down Syndrome.

Worley Gordon , Crissman Blythe G , Cadogan Emily , Milleson Christie , Adkins Deanna W , Kishnani Priya S ,

[24900851] Discovery of AZD3199, An Inhaled Ultralong Acting β2 Receptor Agonist with Rapid Onset of Action.

Stocks Michael J , Alcaraz Lilian , Bailey Andrew , Bonnert Roger , Cadogan Elaine , Christie Jadeen , Dixon John , Connolly Stephen , Cook Anthony , Fisher Adrian , Flaherty Alice , Humphries Alexander , Ingall Anthony , Jordan Stephen , Lawson Mandy , Mullen Alex , Nicholls David , Paine Stuart , Pairaudeau Garry , Young Alan ,

[22659538] Characteristics of AZD9708, a novel, selective β2-adrenoceptor agonist with rapid onset and long duration of action.

Nicholls D J , Jordan S , Cadogan E , Lawson M , Austin R P , Paine S W , Gardiner P , Bonnert R , Connolly S , Young A ,

[22079756] From libraries to candidate: the discovery of new ultra long-acting dibasic β₂-adrenoceptor agonists.

Alcaraz Lilian , Bailey Andrew , Cadogan Elaine , Connolly Stephen , Jewell Robert , Jordan Stephen , Kindon Nicholas , Lister Andrew , Lawson Mandy , Mullen Alexander , Dainty Ian , Nicholls David , Paine Stuart , Pairaudeau Garry , Stocks Michael J , Thorne Phillip , Young Alan ,

[21997333] Late intervention with a myeloperoxidase inhibitor stops progression of experimental chronic obstructive pulmonary disease.

Churg Andrew , Marshall Caroline V , Sin Don D , Bolton Sarah , Zhou Steven , Thain Katherine , Cadogan Elaine B , Maltby Justine , Soars Matthew G , Mallinder Philip R , Wright Joanne L ,

[21723724] Design-driven LO: the discovery of new ultra long acting dibasic β2-adrenoceptor agonists.

Connolly Stephen , Alcaraz Lilian , Bailey Andrew , Cadogan Elaine , Christie Jadeen , Cook Anthony R , Fisher Adrian J , Hill Stephen , Humphries Alexander , Ingall Anthony H , Kane Zoe , Paine Stuart , Pairaudeau Garry , Stocks Michael J , Young Alan ,

[21652207] Design driven HtL: The discovery and synthesis of new high efficacy β₂-agonists.

Stocks Michael J , Alcaraz Lilian , Bailey Andrew , Bonnert Roger , Cadogan Elaine , Christie Jadeen , Connolly Stephen , Cook Anthony , Fisher Adrian , Flaherty Alice , Hill Stephen , Humphries Alexander , Ingall Anthony , Jordan Stephen , Lawson Mandy , Mullen Alex , Nicholls David , Paine Stuart , Pairaudeau Garry , St-Gallay Stephen , Young Alan ,

[21393062] Discriminating between latent and active tuberculosis with multiple biomarker responses.

Frahm Marc , Goswami Neela D , Owzar Kouros , Hecker Emily , Mosher Ann , Cadogan Emily , Nahid Payam , Ferrari Guido , Stout Jason E ,

[18293200] Host inflammatory response profiling in preeclampsia using an in vitro whole blood stimulation model.

Brewster J A , Orsi N M , Gopichandran N , Ekbote U V , Cadogan E , Walker J J ,

[12474235] Type 2 nitric oxide synthase and protein nitration in chronic lung infection.

Hopkins Natalie , Cadogan Elaine , Giles Shay , Bannigan John , McLoughlin Paul ,

[11457811] Chronic airway infection leads to angiogenesis in the pulmonary circulation.

Hopkins N , Cadogan E , Giles S , McLoughlin P ,

[10666061] Chronic hypercapnia inhibits hypoxic pulmonary vascular remodeling.

Ooi H , Cadogan E , Sweeney M , Howell K , O'Regan R G , McLoughlin P ,

[10484470] Enhanced expression of inducible nitric oxide synthase without vasodilator effect in chronically infected lungs.

Cadogan E , Hopkins N , Giles S , Bannigan J G , Moynihan J , McLoughlin P ,

[3512007] Ultrasonography of hepatic portal venous gas due to diverticulitis.

Fataar S , Cadogan E , Spruyt O ,

[160516] Oesophageal ulceration due to slow-release potassium in the presence of left atrial enlargement.

Lubbe W F , Cadogan E S , Kannemeyer A H ,

[14399273] A controlled trial of thiopropazate dihydrochloride (dartalan). chlorpromazine and occupational therapy in chronic schizophrenics.

HAMILTON M , SMITH A L , LAPIDUS H E , Cadogan E P ,

 

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