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Cleary M L 's Articles

[27758892] E2A-PBX1 Remodels Oncogenic Signaling Networks in B-cell Precursor Acute Lymphoid Leukemia.

Duque-Afonso Jesús , Lin Chiou-Hong , Han Kyuho , Wei Michael C , Feng Jue , Kurzer Jason H , Schneidawind Corina , Wong Stephen Hon-Kit , Bassik Michael C , Cleary Michael L ,

[27220664] Inhibition of precursor B-cell malignancy progression by toll-like receptor ligand-induced immune responses.

Fidanza M , Seif A E , DeMicco A , Rolf N , Jo S , Yin B , Li Y , Barrett D M , Duque-Afonso J , Cleary M L , Bassing C H , Grupp S A , Reid G S D ,

[27154821] ASH1L Links Histone H3 Lysine 36 Dimethylation to MLL Leukemia.

Zhu Li , Li Qin , Wong Stephen H K , Huang Min , Klein Brianna J , Shen Jinfeng , Ikenouye Larissa , Onishi Masayuki , Schneidawind Dominik , Buechele Corina , Hansen Loren , Duque-Afonso Jesús , Zhu Fangfang , Martin Gloria Mas , Gozani Or , Majeti Ravindra , Kutateladze Tatiana G , Cleary Michael L ,

[26588248] Conditional Expression of E2A-HLF Induces B-Cell Precursor Death and Myeloproliferative-Like Disease in Knock-In Mice.

Duque-Afonso Jesús , Smith Kevin S , Cleary Michael L ,

[26387756] CD93 Marks a Non-Quiescent Human Leukemia Stem Cell Population and Is Required for Development of MLL-Rearranged Acute Myeloid Leukemia.

Iwasaki Masayuki , Liedtke Michaela , Gentles Andrew J , Cleary Michael L ,

[26351841] Use of Genome Engineering to Create Patient Specific MLL Translocations in Primary Human Hematopoietic Stem and Progenitor Cells.

Breese Erin H , Buechele Corina , Dawson Catherine , Cleary Michael L , Porteus Matthew H ,

[26311362] MLL leukemia induction by genome editing of human CD34+ hematopoietic cells.

Buechele Corina , Breese Erin H , Schneidawind Dominik , Lin Chiou-Hong , Jeong Johan , Duque-Afonso Jesus , Wong Stephen H K , Smith Kevin S , Negrin Robert S , Porteus Matthew , Cleary Michael L ,

[26301816] Comparative genomics reveals multistep pathogenesis of E2A-PBX1 acute lymphoblastic leukemia.

Duque-Afonso Jesús , Feng Jue , Scherer Florian , Lin Chiou-Hong , Wong Stephen H K , Wang Zhong , Iwasaki Masayuki , Cleary Michael L ,

[26190263] The H3K4-Methyl Epigenome Regulates Leukemia Stem Cell Oncogenic Potential.

Wong Stephen H K , Goode David L , Iwasaki Masayuki , Wei Michael C , Kuo Hsu-Ping , Zhu Li , Schneidawind Dominik , Duque-Afonso Jesus , Weng Ziming , Cleary Michael L ,

[25529853] Essential role of PU.1 in maintenance of mixed lineage leukemia-associated leukemic stem cells.

Aikawa Yukiko , Yamagata Kazutsune , Katsumoto Takuo , Shima Yutaka , Shino Mika , Stanley E Richard , Cleary Michael L , Akashi Koichi , Tenen Daniel G , Kitabayashi Issay ,

[25212992] Novel methods and approaches to acute lymphoblastic leukemia drug discovery.

Wei Michael C , Cleary Michael L ,

[24651007] The AML salad bowl.

Duque-Afonso Jesús , Cleary Michael L ,

[24183972] Next-generation NAMPT inhibitors identified by sequential high-throughput phenotypic chemical and functional genomic screens.

Matheny Christina J , Wei Michael C , Bassik Michael C , Donnelly Alicia J , Kampmann Martin , Iwasaki Masayuki , Piloto Obdulio , Solow-Cordero David E , Bouley Donna M , Rau Rachel , Brown Patrick , McManus Michael T , Weissman Jonathan S , Cleary Michael L ,

[24054986] Epigenetic roles of MLL oncoproteins are dependent on NF-κB.

Kuo Hsu-Ping , Wang Zhong , Lee Dung-Fang , Iwasaki Masayuki , Duque-Afonso Jesus , Wong Stephen H K , Lin Chiou-Hong , Figueroa Maria E , Su Jie , Lemischka Ihor R , Cleary Michael L ,

[24040009] MLL becomes functional through intra-molecular interaction not by proteolytic processing.

Yokoyama Akihiko , Ficara Francesca , Murphy Mark J , Meisel Christian , Hatanaka Chikako , Kitabayashi Issay , Cleary Michael L ,

[23660001] Pbx1 restrains myeloid maturation while preserving lymphoid potential in hematopoietic progenitors.

Ficara Francesca , Crisafulli Laura , Lin Chenwei , Iwasaki Masayuki , Smith Kevin S , Zammataro Luca , Cleary Michael L ,

[22849628] Developing and using multiple-choice tests in clinical settings.

Cleary Michelle L , Horsfall Jan ,

[22258599] Genomics: The path to retinoblastoma.

Sage Julien , Cleary Michael L ,

[21922607] PBX1: a novel stage-specific regulator of adipocyte development.

Monteiro Miguel C , Sanyal Mrinmoy , Cleary Michael L , Sengenès Coralie , Bouloumié Anne , Bouloumé Anne , Dani Christian , Billon Nathalie ,

[21741595] Cell of origin in AML: susceptibility to MN1-induced transformation is regulated by the MEIS1/AbdB-like HOX protein complex.

Heuser Michael , Yun Haiyang , Berg Tobias , Yung Eric , Argiropoulos Bob , Kuchenbauer Florian , Park Gyeongsin , Hamwi Iyas , Palmqvist Lars , Lai Courteney K , Leung Malina , Lin Grace , Chaturvedi Anuhar , Thakur Basant Kumar , Iwasaki Masayuki , Bilenky Mikhail , Thiessen Nina , Robertson Gordon , Hirst Martin , Kent David , Wilson Nicola K , Göttgens Bertie , Eaves Connie , Cleary Michael L , Marra Marco , Ganser Arnold , Humphries R Keith ,

[21670200] Proteolytically cleaved MLL subunits are susceptible to distinct degradation pathways.

Yokoyama Akihiko , Ficara Francesca , Murphy Mark J , Meisel Christian , Naresh Alpana , Kitabayashi Issay , Cleary Michael L ,

[21511732] TALE homeodomain proteins regulate site-specific terminal differentiation, LCE genes and epidermal barrier.

Jackson Ben , Brown Stuart J , Avilion Ariel A , O'Shaughnessy Ryan F L , Sully Katherine , Akinduro Olufolake , Murphy Mark , Cleary Michael L , Byrne Carolyn ,

[21451113] MicroRNA programs in normal and aberrant stem and progenitor cells.

Arnold Christopher P , Tan Ruoying , Zhou Baiyu , Yue Si-Biao , Schaffert Steven , Biggs Joseph R , Doyonnas Regis , Lo Miao-Chia , Perry John M , Renault Valérie M , Sacco Alessandra , Somervaille Tim , Viatour Patrick , Brunet Anne , Cleary Michael L , Li Linheng , Sage Julien , Zhang Dong-Er , Blau Helen M , Chen Caifu , Chen Chang-Zheng ,

[21366197] Suggestions for reviewing clinical continuing education courses.

Cleary Michelle L , Walter Garry ,

[21262763] A novel Gli3 enhancer controls the Gli3 spatiotemporal expression pattern through a TALE homeodomain protein binding site.

Coy Sarah , Caamaño Jorge H , Carvajal Jaime , Cleary Michael L , Borycki Anne-Gaëlle ,

[20541704] GSK-3 promotes conditional association of CREB and its coactivators with MEIS1 to facilitate HOX-mediated transcription and oncogenesis.

Wang Zhong , Iwasaki Masayuki , Ficara Francesca , Lin Chenwei , Matheny Christina , Wong Stephen H K , Smith Kevin S , Cleary Michael L ,

[20460131] Molecular mechanism of MLL PHD3 and RNA recognition by the Cyp33 RRM domain.

Hom Robert A , Chang Pei-Yun , Roy Siddhartha , Musselman Catherine A , Glass Karen C , Selezneva Anna I , Gozani Or , Ismagilov Rustem F , Cleary Michael L , Kutateladze Tatiana G ,

[20454944] Grist for the MLL: how do MLL oncogenic fusion proteins generate leukemia stem cells?

Somervaille Tim C P , Cleary Michael L ,

[20452361] Binding of the MLL PHD3 finger to histone H3K4me3 is required for MLL-dependent gene transcription.

Chang Pei-Yun , Hom Robert A , Musselman Catherine A , Zhu Li , Kuo Alex , Gozani Or , Kutateladze Tatiana G , Cleary Michael L ,

[20411885] Giving feedback to learners in clinical and academic settings: practical considerations.

Cleary Michelle L , Walter Garry ,

[20406979] The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression.

Wong Piu , Iwasaki Masayuki , Somervaille Tim C P , Ficara Francesca , Carico Christine , Arnold Christopher , Chen Chang-Zheng , Cleary Michael L ,

[20395419] Self-association mediated by the Ras association 1 domain of AF6 activates the oncogenic potential of MLL-AF6.

Liedtke Michaela , Ayton Paul M , Somervaille Tim C P , Smith Kevin S , Cleary Michael L ,

[19896432] Preview. Mutant CEBPA: Priming Stem Cells for Myeloid Leukemogenesis.

Somervaille Tim C P , Cleary Michael L ,

[20153263] A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription.

Yokoyama Akihiko , Lin Min , Naresh Alpana , Kitabayashi Issay , Cleary Michael L ,

[19959097] Regulating the leukaemia stem cell.

Cleary Michael L ,

[19797217] Essential role for Pbx1 in corneal morphogenesis.

Murphy Mark J , Polok Bozena K , Schorderet Daniel F , Cleary Michael L ,

[19639917] A consideration of contemporary factors influencing professional development in health research.

Cleary Michelle L , Walter Garry , Horsfall Jan , Matheson Sandra ,

[19289854] Therapeutic targeting of MLL.

Liedtke Michaela , Cleary Michael L ,

[19247936] Ectopic Meis1 expression in the mouse limb bud alters P-D patterning in a Pbx1-independent manner.

Mercader Nadia , Selleri Licia , Criado Luis Miguel , Pallares Pilar , Parras Carlos , Cleary Michael L , Torres Miguel ,

[19200802] Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells.

Somervaille Tim C P , Matheny Christina J , Spencer Gary J , Iwasaki Masayuki , Rinn John L , Witten Daniela M , Chang Howard Y , Shurtleff Sheila A , Downing James R , Cleary Michael L ,

[18849531] Pbx1 functions in distinct regulatory networks to pattern the great arteries and cardiac outflow tract.

Chang Ching-Pin , Stankunas Kryn , Shang Ching , Kao Shih-Chu , Twu Karen Y , Cleary Michael L ,

[18806775] Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy.

Wang Zhong , Smith Kevin S , Murphy Mark , Piloto Obdulio , Somervaille Tim C P , Cleary Michael L ,

[18723445] Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart disease.

Stankunas Kryn , Shang Ching , Twu Karen Y , Kao Shih-Chu , Jenkins Nancy A , Copeland Neal G , Sanyal Mrinmoy , Selleri Licia , Cleary Michael L , Chang Ching-Pin ,

[18598942] Menin critically links MLL proteins with LEDGF on cancer-associated target genes.

Yokoyama Akihiko , Cleary Michael L ,

[18462698] Pbx1 regulates self-renewal of long-term hematopoietic stem cells by maintaining their quiescence.

Ficara Francesca , Murphy Mark J , Lin Min , Cleary Michael L ,

[18223323] A novel monoclonal antibody against DOG1 is a sensitive and specific marker for gastrointestinal stromal tumors.

Espinosa Inigo , Lee Cheng-Han , Kim Mi Kyung , Rouse Bich-Tien , Subramanian Subbaya , Montgomery Kelli , Varma Sushama , Corless Christopher L , Heinrich Michael C , Smith Kevin S , Wang Zhong , Rubin Brian , Nielsen Torsten O , Seitz Robert S , Ross Douglas T , West Robert B , Cleary Michael L , van de Rijn Matt ,

[17942707] Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential.

Wong Piu , Iwasaki Masayuki , Somervaille Tim C P , So Chi Wai Eric , So Chai Wai Eric , Cleary Michael L ,

[17891136] Protein arginine-methyltransferase-dependent oncogenesis.

Cheung Ngai , Chan Li Chong , Thompson Alex , Cleary Michael L , So Chi Wai Eric ,

[17244677] B-cell development fails in the absence of the Pbx1 proto-oncogene.

Sanyal Mrinmoy , Tung James W , Karsunky Holger , Zeng Hong , Selleri Licia , Weissman Irving L , Herzenberg Leonore A , Cleary Michael L ,

[17157786] PU.1 and Junb: suppressing the formation of acute myeloid leukemia stem cells.

Somervaille Tim C P , Cleary Michael L ,

 

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