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Gnad Florian 's Articles

[29203670] Kras mutant genetically engineered mouse models of human cancers are genomically heterogeneous.

Chung Wei-Jen , Daemen Anneleen , Cheng Jason H , Long Jason E , Cooper Jonathan E , Wang Bu-Er , Tran Christopher , Singh Mallika , Gnad Florian , Modrusan Zora , Foreman Oded , Junttila Melissa R ,

[29045385] USP7 small-molecule inhibitors interfere with ubiquitin binding.

Kategaya Lorna , Di Lello Paola , Rougé Lionel , Pastor Richard , Clark Kevin R , Drummond Jason , Kleinheinz Tracy , Lin Eva , Upton John-Paul , Prakash Sumit , Heideker Johanna , McCleland Mark , Ritorto Maria Stella , Alessi Dario R , Trost Matthias , Bainbridge Travis W , Kwok Michael C M , Ma Taylur P , Stiffler Zachary , Brasher Bradley , Tang Yinyan , Jaishankar Priyadarshini , Hearn Brian R , Renslo Adam R , Arkin Michelle R , Cohen Frederick , Yu Kebing , Peale Frank , Gnad Florian , Chang Matthew T , Klijn Christiaan , Blackwood Elizabeth , Martin Scott E , Forrest William F , Ernst James A , Ndubaku Chudi , Wang Xiaojing , Beresini Maureen H , Tsui Vickie , Schwerdtfeger Carsten , Blake Robert A , Murray Jeremy , Maurer Till , Wertz Ingrid E ,

[28655764] Role of the E3 ubiquitin ligase RNF157 as a novel downstream effector linking PI3K and MAPK signaling pathways to the cell cycle.

Dogan Taner , Gnad Florian , Chan Jocelyn , Phu Lilian , Young Amy , Chen Mark J , Doll Sophia , Stokes Matthew P , Belvin Marcia , Friedman Lori S , Kirkpatrick Donald S , Hoeflich Klaus P , Hatzivassiliou Georgia ,

[27568559] Recurrent Loss of NFE2L2 Exon 2 Is a Mechanism for Nrf2 Pathway Activation in Human Cancers.

Goldstein Leonard D , Lee James , Gnad Florian , Klijn Christiaan , Schaub Annalisa , Reeder Jens , Daemen Anneleen , Bakalarski Corey E , Holcomb Thomas , Shames David S , Hartmaier Ryan J , Chmielecki Juliann , Seshagiri Somasekar , Gentleman Robert , Stokoe David ,

[27367445] Cellular Interrogation: Exploiting Cell-to-Cell Variability to Discriminate Regulatory Mechanisms in Oscillatory Signalling.

Estrada Javier , Andrew Natalie , Gibson Daniel , Chang Frederick , Gnad Florian , Gunawardena Jeremy ,

[27282143] Quantitative phosphoproteomic analysis of the PI3K-regulated signaling network.

Gnad Florian , Wallin Jeffrey , Edgar Kyle , Doll Sophia , Arnott David , Robillard Liliane , Kirkpatrick Donald S , Stokes Matthew P , Vijapurkar Ulka , Hatzivassiliou Georgia , Friedman Lori S , Belvin Marcia ,

[27273156] Phosphoproteome analysis of the MAPK pathway reveals previously undetected feedback mechanisms.

Gnad Florian , Doll Sophia , Song Kyung , Stokes Matthew P , Moffat John , Liu Bonnie , Arnott David , Wallin Jeffrey , Friedman Lori S , Hatzivassiliou Georgia , Belvin Marcia ,

[27125827] Uncovering a Dual Regulatory Role for Caspases During Endoplasmic Reticulum Stress-induced Cell Death.

Anania Veronica G , Yu Kebing , Gnad Florian , Pferdehirt Rebecca R , Li Han , Ma Taylur P , Jeon Diana , Fortelny Nikolaus , Forrest William , Ashkenazi Avi , Overall Christopher M , Lill Jennie R ,

[26928227] Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations.

Bueno Raphael , Stawiski Eric W , Goldstein Leonard D , Durinck Steffen , De Rienzo Assunta , Modrusan Zora , Gnad Florian , Nguyen Thong T , Jaiswal Bijay S , Chirieac Lucian R , Sciaranghella Daniele , Dao Nhien , Gustafson Corinne E , Munir Kiara J , Hackney Jason A , Chaudhuri Amitabha , Gupta Ravi , Guillory Joseph , Toy Karen , Ha Connie , Chen Ying-Jiun , Stinson Jeremy , Chaudhuri Subhra , Zhang Na , Wu Thomas D , Sugarbaker David J , de Sauvage Frederic J , Richards William G , Seshagiri Somasekar ,

[26752646] CCAT1 is an enhancer-templated RNA that predicts BET sensitivity in colorectal cancer.

McCleland Mark L , Mesh Kathryn , Lorenzana Edward , Chopra Vivek S , Segal Ehud , Watanabe Colin , Haley Benjamin , Mayba Oleg , Yaylaoglu Murat , Gnad Florian , Firestein Ron ,

[26110843] Bioinformatics analysis of thousands of TCGA tumors to determine the involvement of epigenetic regulators in human cancer.

Gnad Florian , Doll Sophia , Manning Gerard , Arnott David , Zhang Zemin ,

[25485619] A comprehensive transcriptional portrait of human cancer cell lines.

Klijn Christiaan , Durinck Steffen , Stawiski Eric W , Haverty Peter M , Jiang Zhaoshi , Liu Hanbin , Degenhardt Jeremiah , Mayba Oleg , Gnad Florian , Liu Jinfeng , Pau Gregoire , Reeder Jens , Cao Yi , Mukhyala Kiran , Selvaraj Suresh K , Yu Mamie , Zynda Gregory J , Brauer Matthew J , Wu Thomas D , Gentleman Robert C , Manning Gerard , Yauch Robert L , Bourgon Richard , Stokoe David , Modrusan Zora , Neve Richard M , de Sauvage Frederic J , Settleman Jeffrey , Seshagiri Somasekar , Zhang Zemin ,

[25159915] Diverse modes of genomic alteration in hepatocellular carcinoma.

Jhunjhunwala Suchit , Jiang Zhaoshi , Stawiski Eric W , Gnad Florian , Liu Jinfeng , Mayba Oleg , Du Pan , Diao Jingyu , Johnson Stephanie , Wong Kwong-Fai , Gao Zhibo , Li Yingrui , Wu Thomas D , Kapadia Sharookh B , Modrusan Zora , French Dorothy M , Luk John M , Seshagiri Somasekar , Zhang Zemin ,

[25074413] PAK1 mediates pancreatic cancer cell migration and resistance to MET inhibition.

Zhou Wei , Jubb Adrian M , Lyle Karen , Xiao Qian , Ong Christy C , Desai Rupal , Fu Ling , Gnad Florian , Song Qinghua , Haverty Peter M , Aust Daniela , Grützmann Robert , Romero Mally , Totpal Klara , Neve Richard M , Yan Yibing , Forrest William F , Wang Yulei , Raja Rajiv , Pilarsky Christian , de Jesus-Acosta Ana , Belvin Marcia , Friedman Lori S , Merchant Mark , Jaffee Elizabeth M , Zheng Lei , Koeppen Hartmut , Hoeflich Klaus P ,

[24807215] Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer.

Liu Jinfeng , McCleland Mark , Stawiski Eric W , Gnad Florian , Mayba Oleg , Haverty Peter M , Durinck Steffen , Chen Ying-Jiun , Klijn Christiaan , Jhunjhunwala Suchit , Lawrence Michael , Liu Hanbin , Wan Yinan , Chopra Vivek , Yaylaoglu Murat B , Yuan Wenlin , Ha Connie , Gilbert Houston N , Reeder Jens , Pau Gregoire , Stinson Jeremy , Stern Howard M , Manning Gerard , Wu Thomas D , Neve Richard M , de Sauvage Frederic J , Modrusan Zora , Seshagiri Somasekar , Firestein Ron , Zhang Zemin ,

[24297535] Integrative analysis of two cell lines derived from a non-small-lung cancer patient--a panomics approach.

Mayba Oleg , Gnad Florian , Peyton Michael , Zhang Fan , Walter Kimberly , Du Pan , Huntley Melanie A , Jiang Zhaoshi , Liu Jinfeng , Haverty Peter M , Gentleman Robert C , Li Ruiqiang , Minna John D , Li Yingrui , Shames David S , Zhang Zemin ,

[23819521] Assessment of computational methods for predicting the effects of missense mutations in human cancers.

Gnad Florian , Baucom Albion , Mukhyala Kiran , Manning Gerard , Zhang Zemin ,

[23608596] Systems-wide analysis of K-Ras, Cdc42, and PAK4 signaling by quantitative phosphoproteomics.

Gnad Florian , Young Amy , Zhou Wei , Lyle Karen , Ong Christy C , Stokes Matthew P , Silva Jeffrey C , Belvin Marcia , Friedman Lori S , Koeppen Hartmut , Minden Audrey , Hoeflich Klaus P ,

[23033341] Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events.

Liu Jinfeng , Lee William , Jiang Zhaoshi , Chen Zhongqiang , Jhunjhunwala Suchit , Haverty Peter M , Gnad Florian , Guan Yinghui , Gilbert Houston N , Stinson Jeremy , Klijn Christiaan , Guillory Joseph , Bhatt Deepali , Vartanian Steffan , Walter Kimberly , Chan Jocelyn , Holcomb Thomas , Dijkgraaf Peter , Johnson Stephanie , Koeman Julie , Minna John D , Gazdar Adi F , Stern Howard M , Hoeflich Klaus P , Wu Thomas D , Settleman Jeff , de Sauvage Frederic J , Gentleman Robert C , Neve Richard M , Stokoe David , Modrusan Zora , Seshagiri Somasekar , Shames David S , Zhang Zemin ,

[22968445] Extensive quantitative remodeling of the proteome between normal colon tissue and adenocarcinoma.

Wiśniewski Jacek R , Ostasiewicz Paweł , Duś Kamila , Zielińska Dorota F , Gnad Florian , Mann Matthias ,

[22941189] Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer.

Rudin Charles M , Durinck Steffen , Stawiski Eric W , Poirier John T , Modrusan Zora , Shames David S , Bergbower Emily A , Guan Yinghui , Shin James , Guillory Joseph , Rivers Celina Sanchez , Foo Catherine K , Bhatt Deepali , Stinson Jeremy , Gnad Florian , Haverty Peter M , Gentleman Robert , Chaudhuri Subhra , Janakiraman Vasantharajan , Jaiswal Bijay S , Parikh Chaitali , Yuan Wenlin , Zhang Zemin , Koeppen Hartmut , Wu Thomas D , Stern Howard M , Yauch Robert L , Huffman Kenneth E , Paskulin Diego D , Illei Peter B , Varella-Garcia Marileila , Gazdar Adi F , de Sauvage Frederic J , Bourgon Richard , Minna John D , Brock Malcolm V , Seshagiri Somasekar ,

[22923814] Phosphoproteome of Pristionchus pacificus provides insights into architecture of signaling networks in nematode models.

Borchert Nadine , Krug Karsten , Gnad Florian , Sinha Amit , Sommer Ralf J , Macek Boris ,

[22895193] Recurrent R-spondin fusions in colon cancer.

Seshagiri Somasekar , Stawiski Eric W , Durinck Steffen , Modrusan Zora , Storm Elaine E , Conboy Caitlin B , Chaudhuri Subhra , Guan Yinghui , Janakiraman Vasantharajan , Jaiswal Bijay S , Guillory Joseph , Ha Connie , Dijkgraaf Gerrit J P , Stinson Jeremy , Gnad Florian , Huntley Melanie A , Degenhardt Jeremiah D , Haverty Peter M , Bourgon Richard , Wang Weiru , Koeppen Hartmut , Gentleman Robert , Starr Timothy K , Zhang Zemin , Largaespada David A , Wu Thomas D , de Sauvage Frederic J ,

[22633491] Mapping N-glycosylation sites across seven evolutionarily distant species reveals a divergent substrate proteome despite a common core machinery.

Zielinska Dorota F , Gnad Florian , Schropp Katharina , Wiśniewski Jacek R , Mann Matthias ,

[22426344] Proteus: a web-based, context-specific modelling tool for molecular networks.

Gnad Florian , Estrada Javier , Gunawardena Jeremy ,

[22050367] Systems-wide proteomic analysis in mammalian cells reveals conserved, functional protein turnover.

Cambridge Sidney B , Gnad Florian , Nguyen Chuong , Bermejo Justo Lorenzo , Krüger Marcus , Mann Matthias ,

[21966514] Profiling the Trypanosoma cruzi phosphoproteome.

Marchini Fabricio K , de Godoy Lyris M F , Rampazzo Rita C P , Pavoni Daniela P , Probst Christian M , Gnad Florian , Mann Matthias , Krieger Marco A ,

[21907143] C2 domain-containing phosphoprotein CDP138 regulates GLUT4 insertion into the plasma membrane.

Xie Xiangyang , Gong Zhenwei , Mansuy-Aubert Virginie , Zhou Qiong L , Tatulian Suren A , Sehrt Daniel , Gnad Florian , Brill Laurence M , Motamedchaboki Khatereh , Chen Yu , Czech Michael P , Mann Matthias , Krüger Marcus , Jiang Zhen Y ,

[21081558] PHOSIDA 2011: the posttranslational modification database.

Gnad Florian , Gunawardena Jeremy , Mann Matthias ,

[20797634] Site-specific identification of SUMO-2 targets in cells reveals an inverted SUMOylation motif and a hydrophobic cluster SUMOylation motif.

Matic Ivan , Schimmel Joost , Hendriks Ivo A , van Santen Maria A , van de Rijke Frans , van Dam Hans , Gnad Florian , Mann Matthias , Vertegaal Alfred C O ,

[20688971] Evolutionary constraints of phosphorylation in eukaryotes, prokaryotes, and mitochondria.

Gnad Florian , Forner Francesca , Zielinska Dorota F , Birney Ewan , Gunawardena Jeremy , Mann Matthias ,

[20510933] Precision mapping of an in vivo N-glycoproteome reveals rigid topological and sequence constraints.

Zielinska Dorota F , Gnad Florian , Wiśniewski Jacek R , Mann Matthias ,

[20509597] Stable isotope labeling by amino acids in cell culture (SILAC) applied to quantitative proteomics of Bacillus subtilis.

Soufi Boumediene , Kumar Chanchal , Gnad Florian , Mann Matthias , Mijakovic Ivan , Macek Boris ,

[20505001] Predicting post-translational lysine acetylation using support vector machines.

Gnad Florian , Ren Shubin , Choudhary Chunaram , Cox Jürgen , Mann Matthias ,

[20415495] Brain phosphoproteome obtained by a FASP-based method reveals plasma membrane protein topology.

Wiśniewski Jacek R , Nagaraj Nagarjuna , Zougman Alexandre , Gnad Florian , Mann Matthias ,

[20068231] Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

Olsen Jesper V , Vermeulen Michiel , Santamaria Anna , Kumar Chanchal , Miller Martin L , Jensen Lars J , Gnad Florian , Cox Jürgen , Jensen Thomas S , Nigg Erich A , Brunak Søren , Mann Matthias ,

[19795423] High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.

Gnad Florian , de Godoy Lyris M F , Cox Jürgen , Neuhauser Nadin , Ren Shubin , Olsen Jesper V , Mann Matthias ,

[19608861] Lysine acetylation targets protein complexes and co-regulates major cellular functions.

Choudhary Chunaram , Kumar Chanchal , Gnad Florian , Nielsen Michael L , Rehman Michael , Walther Tobias C , Olsen Jesper V , Mann Matthias ,

[19530675] Caenorhabditis elegans has a phosphoproteome atypical for metazoans that is enriched in developmental and sex determination proteins.

Zielinska Dorota F , Gnad Florian , Jedrusik-Bode Monika , Wiśniewski Jacek R , Mann Matthias ,

[19429919] Systems-wide analysis of a phosphatase knock-down by quantitative proteomics and phosphoproteomics.

Hilger Maximiliane , Bonaldi Tiziana , Gnad Florian , Mann Matthias ,

[19369195] Large-scale proteomics analysis of the human kinome.

Oppermann Felix S , Gnad Florian , Olsen Jesper V , Hornberger Renate , Greff Zoltán , Kéri György , Mann Matthias , Daub Henrik ,

[19367708] Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry.

Zanivan Sara , Gnad Florian , Wickström Sara A , Geiger Tami , Macek Boris , Cox Jürgen , Fässler Reinhard , Mann Matthias ,

[19274099] Ser/Thr/Tyr protein phosphorylation in the archaeon Halobacterium salinarum--a representative of the third domain of life.

Aivaliotis Michalis , Macek Boris , Gnad Florian , Reichelt Peter , Mann Matthias , Oesterhelt Dieter ,

[18948283] MAPU 2.0: high-accuracy proteomes mapped to genomes.

Gnad Florian , Oroshi Mario , Birney Ewan , Mann Matthias ,

[18846507] Quantitative phosphoproteome analysis of a mouse liver cell line reveals specificity of phosphatase inhibitors.

Pan Cuiping , Gnad Florian , Olsen Jesper V , Mann Matthias ,

[18691976] Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

Daub Henrik , Olsen Jesper V , Bairlein Michaela , Gnad Florian , Oppermann Felix S , Körner Roman , Greff Zoltán , Kéri György , Stemmann Olaf , Mann Matthias ,

[18668697] The Ser/Thr/Tyr phosphoproteome of Lactococcus lactis IL1403 reveals multiply phosphorylated proteins.

Soufi Boumediene , Gnad Florian , Jensen Peter Ruhdal , Petranovic Dina , Mann Matthias , Mijakovic Ivan , Macek Boris ,

[18259167] Human Proteinpedia enables sharing of human protein data.

Mathivanan Suresh , Ahmed Mukhtar , Ahn Natalie G , Alexandre Hainard , Amanchy Ramars , Andrews Philip C , Bader Joel S , Balgley Brian M , Bantscheff Marcus , Bennett Keiryn L , Björling Erik , Blagoev Blagoy , Bose Ron , Brahmachari Samir K , Burlingame Alma S , Bustelo Xosé R , Cagney Gerard , Cantin Greg T , Cardasis Helene L , Celis Julio E , Chaerkady Raghothama , Chu Feixia , Cole Philip A , Costello Catherine E , Cotter Robert J , Crockett David , DeLany James P , De Marzo Angelo M , DeSouza Leroi V , Deutsch Eric W , Dransfield Eric , Drewes Gerard , Droit Arnaud , Dunn Michael J , Elenitoba-Johnson Kojo , Ewing Rob M , Van Eyk Jennifer , Faca Vitor , Falkner Jayson , Fang Xiangming , Fenselau Catherine , Figeys Daniel , Gagné Pierre , Gelfi Cecilia , Gevaert Kris , Gimble Jeffrey M , Gnad Florian , Goel Renu , Gromov Pavel , Hanash Samir M , Hancock William S , Harsha H C , Hart Gerald , Hays Faith , He Fuchu , Hebbar Prashantha , Helsens Kenny , Hermeking Heiko , Hide Winston , Hjernø Karin , Hochstrasser Denis F , Hofmann Oliver , Horn David M , Hruban Ralph H , Ibarrola Nieves , James Peter , Jensen Ole N , Jensen Pia Hønnerup , Jung Peter , Kandasamy Kumaran , Kheterpal Indu , Kikuno Reiko F , Korf Ulrike , Körner Roman , Kuster Bernhard , Kwon Min-Seok , Lee Hyoung-Joo , Lee Young-Jin , Lefevre Michael , Lehvaslaiho Minna , Lescuyer Pierre , Levander Fredrik , Lim Megan S , Löbke Christian , Loo Joseph A , Mann Matthias , Martens Lennart , Martinez-Heredia Juan , McComb Mark , McRedmond James , Mehrle Alexander , Menon Rajasree , Miller Christine A , Mischak Harald , Mohan S Sujatha , Mohmood Riaz , Molina Henrik , Moran Michael F , Morgan James D , Moritz Robert , Morzel Martine , Muddiman David C , Nalli Anuradha , Navarro J Daniel , Neubert Thomas A , Ohara Osamu , Oliva Rafael , Omenn Gilbert S , Oyama Masaaki , Paik Young-Ki , Pennington Kyla , Pepperkok Rainer , Periaswamy Balamurugan , Petricoin Emanuel F , Poirier Guy G , Prasad T S Keshava , Purvine Samuel O , Rahiman B Abdul , Ramachandran Prasanna , Ramachandra Y L , Rice Robert H , Rick Jens , Ronnholm Ragna H , Salonen Johanna , Sanchez Jean-Charles , Sayd Thierry , Seshi Beerelli , Shankari Kripa , Sheng Shi Jun , Shetty Vivekananda , Shivakumar K , Simpson Richard J , Sirdeshmukh Ravi , Siu K W Michael , Smith Jeffrey C , Smith Richard D , States David J , Sugano Sumio , Sullivan Matthew , Superti-Furga Giulio , Takatalo Maarit , Thongboonkerd Visith , Trinidad Jonathan C , Uhlen Mathias , Vandekerckhove Joël , Vasilescu Julian , Veenstra Timothy D , Vidal-Taboada José-Manuel , Vihinen Mauno , Wait Robin , Wang Xiaoyue , Wiemann Stefan , Wu Billy , Xu Tao , Yates John R , Zhong Jun , Zhou Ming , Zhu Yunping , Zurbig Petra , Pandey Akhilesh ,

[18039369] PHOSIDA (phosphorylation site database): management, structural and evolutionary investigation, and prediction of phosphosites.

Gnad Florian , Ren Shubin , Cox Juergen , Olsen Jesper V , Macek Boris , Oroshi Mario , Mann Matthias ,

[17938405] Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation.

Macek Boris , Gnad Florian , Soufi Boumediene , Kumar Chanchal , Olsen Jesper V , Mijakovic Ivan , Mann Matthias ,

 

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