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Ichihara E 's Articles

[30276451] A phase II trial of EGFR-TKI readministration with afatinib in advanced non-small-cell lung cancer harboring a sensitive non-T790M EGFR mutation: Okayama Lung Cancer Study Group trial 1403.

Oda Naohiro , Hotta Kastuyuki , Ninomiya Kiichiro , Minami Daisuke , Ichihara Eiki , Murakami Toshi , Yokoyama Toshihide , Ichikawa Hirohisa , Chikamori Kenichi , Takigawa Nagio , Ochi Nobuaki , Harita Shingo , Maeda Yoshinobu , Kiura Katsuyuki ,

[30159691] Significance of re-biopsy of histological tumor samples in advanced non-small-cell lung cancer in clinical practice.

Hotta Katsuyuki , Ninomiya Kiichiro , Ichihara Eiki , Kiura Katsuyuki ,

[30053332] Combined effect of cabozantinib and gefitinib in crizotinib-resistant lung tumors harboring ROS1 fusions.

Kato Yuka , Ninomiya Kiichiro , Ohashi Kadoaki , Tomida Shuta , Makimoto Go , Watanabe Hiromi , Kudo Kenichiro , Matsumoto Shingo , Umemura Shigeki , Goto Koichi , Ichihara Eiki , Ninomiya Takashi , Kubo Toshio , Sato Akiko , Hotta Katsuyuki , Tabata Masahiro , Toyooka Shinichi , Maeda Yoshinobu , Kiura Katsuyuki ,

[30034635] Clinical significance of repeat rebiopsy in detecting the EGFR T790M secondary mutation in patients with non-small cell lung cancer.

Ichihara Eiki , Hotta Katsuyuki , Kubo Toshio , Higashionna Tsukasa , Ninomiya Kiichiro , Ohashi Kadoaki , Tabata Masahiro , Maeda Yoshinobu , Kiura Katsuyuki ,

[29926012] Randomized Phase II Study Comparing Mannitol with Furosemide for the Prevention of Renal Toxicity Induced by Cisplatin-based Chemotherapy with Short-term Low-volume Hydration in Advanced Non-small Cell Lung Cancer: The OLCSG1406 Study Protocol.

Makimoto Go , Ichihara Eiki , Hotta Katsuyuki , Ninomiya Kiichiro , Oze Isao , Minami Daisuke , Ninomiya Takashi , Kubo Toshio , Ohashi Kadoaki , Tabata Masahiro , Maeda Yoshinobu , Kiura Katsuyuki ,

[29386539] MET or NRAS amplification is an acquired resistance mechanism to the third-generation EGFR inhibitor naquotinib.

Ninomiya Kiichiro , Ohashi Kadoaki , Makimoto Go , Tomida Shuta , Higo Hisao , Kayatani Hiroe , Ninomiya Takashi , Kubo Toshio , Ichihara Eiki , Hotta Katsuyuki , Tabata Masahiro , Maeda Yoshinobu , Kiura Katsuyuki ,

[29313813] A Phase II Study of Trastuzumab Emtansine in HER2-Positive Non-Small Cell Lung Cancer.

Hotta Katsuyuki , Aoe Keisuke , Kozuki Toshiyuki , Ohashi Kadoaki , Ninomiya Kiichiro , Ichihara Eiki , Kubo Toshio , Ninomiya Takashi , Chikamori Kenichi , Harada Daijiro , Nogami Naoyuki , Hirata Taizo , Hinotsu Shiro , Toyooka Shinichi , Kiura Katsuyuki ,

[29276223] Effects of (-)-epigallocatechin-3-gallate on EGFR- or Fusion Gene-driven Lung Cancer Cells.

Honda Yoshihiro , Takigawa Nagio , Ichihara Eiki , Ninomiya Takashi , Kubo Toshio , Ochi Nobuaki , Yasugi Masayuki , Murakami Toshi , Yamane Hiromichi , Tanimoto Mitsune , Kiura Katsuyuki ,

[29191594] A phase II trial of carboplatin plus S-1 for elderly patients with advanced non-small-cell lung cancer with wild-type epidermal growth factor receptor: The Okayama Lung Cancer Study Group Trial 1202.

Kuyama Shoichi , Ochi Nobuaki , Bessho Akihiro , Hotta Katsuyuki , Ikeda Genyo , Kishino Daizo , Kubo Toshio , Harada Daijiro , Fujimoto Nobukazu , Nakanishi Masamoto , Umeno Takahiro , Okada Toshiaki , Chikamori Kenichi , Yamagishi Tomoko , Ohashi Kadoaki , Ichihara Eiki , Takigawa Nagio , Tanimoto Mitsune , Kiura Katsuyuki ,

[29101033] Potential influence of interleukin-6 on the therapeutic effect of gefitinib in patients with advanced non-small cell lung cancer harbouring EGFR mutations.

Tamura Tomoki , Kato Yuka , Ohashi Kadoaki , Ninomiya Kiichiro , Makimoto Go , Gotoda Hiroko , Kubo Toshio , Ichihara Eiki , Tanaka Takehiro , Ichimura Koichi , Maeda Yoshinobu , Hotta Katsuyuki , Kiura Katsuyuki ,

[29042706] Protective Effects of Bisoprolol against Acute Exacerbation in Moderate-to-Severe Chronic Obstructive Pulmonary Disease.

Taniguchi Akihiko , Miyahara Nobuaki , Oda Naohiro , Morichika Daisuke , Ichihara Eiki , Oze Isao , Tanimoto Yasushi , Ichikawa Hirohisa , Fujii Utako , Tanimoto Mitsune , Kanehiro Arihiko , Kiura Katsuyuki ,

[28781309] Congestive Heart Failure During Osimertinib Treatment for Epidermal Growth Factor Receptor (EGFR)-mutant Non-small Cell Lung Cancer (NSCLC).

Watanabe Hiromi , Ichihara Eiki , Kano Hirohisa , Ninomiya Kiichiro , Tanimoto Mitsune , Kiura Katsuyuki ,

[28705305] Clinical characteristics of Japanese candidates for lung transplant for interstitial lung disease and risk factors for early death while on the waiting list.

Higo Hisao , Kurosaki Takeshi , Ichihara Eiki , Kubo Toshio , Miyoshi Kentaroh , Otani Shinji , Sugimoto Seiichiro , Yamane Masaomi , Miyahara Nobuaki , Kiura Katsuyuki , Miyoshi Shinichiro , Oto Takahiro ,

[28687482] Treatment Rationale and Design for J-SONIC: A Randomized Study of Carboplatin Plus Nab-paclitaxel With or Without Nintedanib for Advanced Non-Small-cell Lung Cancer With Idiopathic Pulmonary Fibrosis.

Otsubo Kohei , Kishimoto Junji , Kenmotsu Hirotsugu , Minegishi Yuji , Ichihara Eiki , Shiraki Akira , Kato Terufumi , Atagi Shinji , Horinouchi Hidehito , Ando Masahiko , Kondoh Yasuhiro , Kusumoto Masahiko , Ichikado Kazuya , Yamamoto Nobuyuki , Nakanishi Yoichi , Okamoto Isamu ,

[28416483] SFK/FAK Signaling Attenuates Osimertinib Efficacy in Both Drug-Sensitive and Drug-Resistant Models of EGFR-Mutant Lung Cancer.

Ichihara Eiki , Westover David , Meador Catherine B , Yan Yingjun , Bauer Joshua A , Lu Pengcheng , Ye Fei , Kulick Amanda , de Stanchina Elisa , McEwen Robert , Ladanyi Marc , Cross Darren , Pao William , Lovly Christine M ,

[28388009] Triplet therapy with afatinib, cetuximab, and bevacizumab induces deep remission in lung cancer cells harboring EGFR T790M in vivo.

Kudo Kenichiro , Ohashi Kadoaki , Makimoto Go , Higo Hisao , Kato Yuka , Kayatani Hiroe , Kurata Yasuko , Takami Yoichiro , Minami Daisuke , Ninomiya Takashi , Kubo Toshio , Ichihara Eiki , Sato Akiko , Hotta Katsuyuki , Yoshino Tadashi , Tanimoto Mitsune , Kiura Katsuyuki ,

[28334767] Discomfort during bronchoscopy performed after endobronchial intubation with fentanyl and midazolam: a prospective study.

Minami Daisuke , Takigawa Nagio , Kano Hirohisa , Ninomiya Takashi , Kubo Toshio , Ichihara Eiki , Ohashi Kadoaki , Sato Akiko , Hotta Katsuyuki , Tabata Masahiro , Tanimoto Mitsune , Kiura Katsuyuki ,

[27847247] Three-Arm Randomized Trial of Sodium Alginate for Preventing Radiation-Induced Esophagitis in Locally Advanced Non-Small Cell Lung Cancer Receiving Concurrent Chemoradiotherapy: The OLCSG1401 Study Protocol.

Ninomiya Kiichiro , Ichihara Eiki , Hotta Katsuyuki , Sone Naoyuki , Murakami Toshi , Harada Daijiro , Oze Isao , Kubo Toshio , Tanaka Hisaaki , Kuyama Shoichi , Kishino Daizo , Bessho Akihiro , Harita Shingo , Katsui Kuniaki , Tanimoto Mitsune , Kiura Katsuyuki ,

[27590708] Potential influence of being overweight on the development of hepatic dysfunction in Japanese patients with EGFR-mutated non-small cell lung cancer undergoing gefitinib monotherapy: the Okayama Lung Cancer Study Group experience.

Oda Naohiro , Hotta Katsuyuki , Yoshioka Hiroshige , Kudo Kenichiro , Ichihara Eiki , Kato Yuka , Ninomiya Kiichiro , Minami Daisuke , Ninomiya Takashi , Kubo Toshio , Ohashi Kadoaki , Sato Akiko , Takigawa Nagio , Tabata Masahiro , Tanimoto Mitsune , Kiura Katsuyuki ,

[27405684] Protocol Design for the Bench to Bed Trial in Alectinib-Refractory Non-Small-Cell Lung Cancer Patients Harboring the EML4-ALK Fusion Gene (ALRIGHT/OLCSG1405).

Isozaki Hideko , Hotta Katsuyuki , Ichihara Eiki , Takigawa Nagio , Ohashi Kadoaki , Kubo Toshio , Ninomiya Takashi , Ninomiya Kiichiro , Oda Naohiro , Yoshioka Hiroshige , Ichikawa Hirohisa , Inoue Masaaki , Takata Ichiro , Shibayama Takuo , Kuyama Shoichi , Sugimoto Keisuke , Harada Daijiro , Harita Shingo , Sendo Toshiaki , Tanimoto Mitsune , Kiura Katsuyuki ,

[27549668] Effect of Vandetanib on Lung Tumorigenesis in Transgenic Mice Carrying an Activating Egfr Gene Mutation.

Osawa Masahiro , Ohashi Kadoaki , Kubo Toshio , Ichihara Eiki , Takata Saburo , Takigawa Nagio , Takata Minoru , Tanimoto Mitsune , Kiura Katsuyuki ,

[27506489] Phase II Study of the EGFR-TKI Rechallenge With Afatinib in Patients With Advanced NSCLC Harboring Sensitive EGFR Mutation Without T790M: Okayama Lung Cancer Study Group Trial OLCSG 1403.

Oda Naohiro , Ichihara Eiki , Hotta Katsuyuki , Ninomiya Kiichiro , Ninomiya Takashi , Kubo Toshio , Minami Daisuke , Murakami Toshi , Yokoyama Toshihide , Harada Daijiro , Kuyama Shoichi , Ichikawa Hirohisa , Inoue Koji , Kishino Daizo , Inoue Masaaki , Takigawa Nagio , Shibayama Takuo , Harita Shingo , Tanimoto Mitsune , Kiura Katsuyuki ,

[27102076] EGFR Fusions as Novel Therapeutic Targets in Lung Cancer.

Konduri Kartik , Gallant Jean-Nicolas , Chae Young Kwang , Giles Francis J , Gitlitz Barbara J , Gowen Kyle , Ichihara Eiki , Owonikoko Taofeek K , Peddareddigari Vijay , Ramalingam Suresh S , Reddy Satyanarayan K , Eaby-Sandy Beth , Vavalà Tiziana , Whiteley Andrew , Chen Heidi , Yan Yingjun , Sheehan Jonathan H , Meiler Jens , Morosini Deborah , Ross Jeffrey S , Stephens Philip J , Miller Vincent A , Ali Siraj M , Lovly Christine M ,

[26719536] Non-Small Cell Lung Cancer Cells Acquire Resistance to the ALK Inhibitor Alectinib by Activating Alternative Receptor Tyrosine Kinases.

Isozaki Hideko , Ichihara Eiki , Takigawa Nagio , Ohashi Kadoaki , Ochi Nobuaki , Yasugi Masayuki , Ninomiya Takashi , Yamane Hiromichi , Hotta Katsuyuki , Sakai Katsuya , Matsumoto Kunio , Hosokawa Shinobu , Bessho Akihiro , Sendo Toshiaki , Tanimoto Mitsune , Kiura Katsuyuki ,

[26301689] RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK-positive lung cancer.

Hrustanovic Gorjan , Olivas Victor , Pazarentzos Evangelos , Tulpule Asmin , Asthana Saurabh , Blakely Collin M , Okimoto Ross A , Lin Luping , Neel Dana S , Sabnis Amit , Flanagan Jennifer , Chan Elton , Varella-Garcia Marileila , Aisner Dara L , Vaishnavi Aria , Ou Sai-Hong I , Collisson Eric A , Ichihara Eiki , Mack Philip C , Lovly Christine M , Karachaliou Niki , Rosell Rafael , Riess Jonathan W , Doebele Robert C , Bivona Trever G ,

[26200288] Challenges in Bevacizumab and Gefitinib Combination Therapy for Patients with Non-Small-Cell Lung Cancer.

Ichihara Eiki , Hotta Katsuyuki , Kiura Katsuyuki ,

[26152920] Shades of T790M: Intratumor Heterogeneity in EGFR-Mutant Lung Cancer.

Ichihara Eiki , Lovly Christine M ,

[26093520] Short-term low-volume hydration in cisplatin-based chemotherapy for patients with lung cancer: the second prospective feasibility study in the Okayama Lung Cancer Study Group Trial 1201.

Ninomiya Kiichiro , Hotta Katsuyuki , Hisamoto-Sato Akiko , Ichihara Eiki , Gotoda Hiroko , Morichika Daisuke , Tamura Tomoki , Kayatani Hiroe , Minami Daisuke , Kubo Toshio , Tabata Masahiro , Tanimoto Mitsune , Kiura Katsuyuki ,

[26037206] Impact of body surface area on survival in EGFR-mutant non-small cell lung cancer patients treated with gefitinib monotherapy: observational study of the Okayama Lung Cancer Study Group 0703.

Kudo Kenichiro , Hotta Katsuyuki , Ichihara Eiki , Yoshioka Hiroshige , Kunimasa Kei , Tsubouchi Kazuya , Iwasaku Masahiro , Kato Yuka , Oze Isao , Takigawa Nagio , Tanimoto Mitsune , Kiura Katsuyuki ,

[25870145] Acquired Resistance to the Mutant-Selective EGFR Inhibitor AZD9291 Is Associated with Increased Dependence on RAS Signaling in Preclinical Models.

Eberlein Catherine A , Stetson Daniel , Markovets Aleksandra A , Al-Kadhimi Katherine J , Lai Zhongwu , Fisher Paul R , Meador Catherine B , Spitzler Paula , Ichihara Eiki , Ross Sarah J , Ahdesmaki Miika J , Ahmed Ambar , Ratcliffe Laura E , O'Brien Elizabeth L Christey , Barnes Claire H , Brown Henry , Smith Paul D , Dry Jonathan R , Beran Garry , Thress Kenneth S , Dougherty Brian , Pao William , Cross Darren A E ,

[25695221] Phase II trial of gefitinib in combination with bevacizumab as first-line therapy for advanced non-small cell lung cancer with activating EGFR gene mutations: the Okayama Lung Cancer Study Group Trial 1001.

Ichihara Eiki , Hotta Katsuyuki , Nogami Naoyuki , Kuyama Shoichi , Kishino Daizo , Fujii Masanori , Kozuki Toshiyuki , Tabata Masahiro , Harada Daijiro , Chikamori Kenichi , Aoe Keisuke , Ueoka Hiroshi , Hosokawa Shinobu , Bessho Akihiro , Hisamoto-Sato Akiko , Kubo Toshio , Oze Isao , Takigawa Nagio , Tanimoto Mitsune , Kiura Katsuyuki ,

[25170107] A new human lung adenocarcinoma cell line harboring the EML4-ALK fusion gene.

Isozaki Hideko , Yasugi Masayuki , Takigawa Nagio , Hotta Katsuyuki , Ichihara Eiki , Taniguchi Akihiko , Toyooka Shinichi , Hashida Shinsuke , Sendo Toshiaki , Tanimoto Mitsune , Kiura Katsuyuki ,

[24893891] AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer.

Cross Darren A E , Ashton Susan E , Ghiorghiu Serban , Eberlein Cath , Nebhan Caroline A , Spitzler Paula J , Orme Jonathon P , Finlay M Raymond V , Ward Richard A , Mellor Martine J , Hughes Gareth , Rahi Amar , Jacobs Vivien N , Red Brewer Monica , Ichihara Eiki , Sun Jing , Jin Hailing , Ballard Peter , Al-Kadhimi Katherine , Rowlinson Rachel , Klinowska Teresa , Richmond Graham H P , Cantarini Mireille , Kim Dong-Wan , Ranson Malcolm R , Pao William ,

[24768699] Everolimus prolonged survival in transgenic mice with EGFR-driven lung tumors.

Yasugi Masayuki , Takigawa Nagio , Ochi Nobuaki , Ohashi Kadoaki , Harada Daijiro , Ninomiya Takashi , Murakami Toshi , Honda Yoshihiro , Ichihara Eiki , Tanimoto Mitsune , Kiura Katsuyuki ,

[24633759] Factor associated with failure to administer subsequent treatment after progression in the first-line chemotherapy in EGFR-mutant non-small cell lung cancer: Okayama Lung Cancer Study Group experience.

Kato Yuka , Hotta Katsuyuki , Takigawa Nagio , Nogami Naoyuki , Kozuki Toshiyuki , Sato Akiko , Ichihara Eiki , Kudo Kenichiro , Oze Isao , Tabata Masahiro , Shinkai Tetsu , Tanimoto Mitsune , Kiura Katsuyuki ,

[24440771] Src mediates ERK reactivation in gefitinib resistance in non-small cell lung cancer.

Ochi Nobuaki , Takigawa Nagio , Harada Daijiro , Yasugi Masayuki , Ichihara Eiki , Hotta Katsuyuki , Tabata Masahiro , Tanimoto Mitsune , Kiura Katsuyuki ,

[24238495] Effect of AZD1480 in an epidermal growth factor receptor-driven lung cancer model.

Murakami Toshi , Takigawa Nagio , Ninomiya Takashi , Ochi Nobuaki , Yasugi Masaaki , Honda Yoshihiro , Kubo Toshio , Ichihara Eiki , Hotta Katsuyuki , Tanimoto Mitsune , Kiura Katsuyuki ,

[24082005] Reappraisal of short-term low-volume hydration in cisplatin-based chemotherapy: results of a prospective feasibility study in advanced lung cancer in the Okayama Lung Cancer Study Group Trial 1002.

Hotta Katsuyuki , Takigawa Nagio , Hisamoto-Sato Akiko , Ichihara Eiki , Kudo Kenichiro , Uchida Koji , Yanase-Nakamura Kayo , Tanaka Hisaaki , Kato Yuka , Tabata Masahiro , Tanimoto Mitsune , Kiura Katsuyuki ,

[24033722] Lower gefitinib dose led to earlier resistance acquisition before emergence of T790M mutation in epidermal growth factor receptor-mutated lung cancer model.

Hayakawa Hiromi , Ichihara Eiki , Ohashi Kadoaki , Ninomiya Takashi , Yasugi Masayuki , Takata Saburo , Sakai Katsuya , Matsumoto Kunio , Takigawa Nagio , Tanimoto Mitsune , Kiura Katsuyuki ,

[23997237] Usefulness of endobronchial ultrasound-guided transbronchial needle aspiration in distinguishing sarcoidosis from recurrent cancer in patients with lymphadenopathy after surgery.

Minami Daisuke , Takigawa Nagio , Hayakawa Hiromi , Mizuta Makoto , Kudo Kenichiro , Uchida Kozi , Ichihara Eiki , Sato Akiko , Hotta Katsuyuki , Tabata Masahiro , Tanimoto Mitsune , Kiura Katsuyuki ,

[23809059] Impact of physical size on gefitinib efficacy in patients with non-small cell lung cancer harboring EGFR mutations.

Ichihara Eiki , Hotta Katsuyuki , Takigawa Nagio , Kudo Kenichiro , Kato Yuka , Honda Yoshihiro , Hayakawa Hiromi , Minami Daisuke , Sato Akiko , Tabata Masahiro , Tanimoto Mitsune , Kiura Katsuyuki ,

[23761220] Antitumor impact of p14ARF on gefitinib-resistant non-small cell lung cancers.

Saito Ken , Takigawa Nagio , Ohtani Naoko , Iioka Hidekazu , Tomita Yuki , Ueda Ryuzo , Fukuoka Junya , Kuwahara Kazuhiko , Ichihara Eiki , Kiura Katsuyuki , Kondo Eisaku ,

[23542356] Acquired resistance to EGFR inhibitors is associated with a manifestation of stem cell-like properties in cancer cells.

Shien Kazuhiko , Toyooka Shinichi , Yamamoto Hiromasa , Soh Junichi , Jida Masaru , Thu Kelsie L , Hashida Shinsuke , Maki Yuho , Ichihara Eiki , Asano Hiroaki , Tsukuda Kazunori , Takigawa Nagio , Kiura Katsuyuki , Gazdar Adi F , Lam Wan L , Miyoshi Shinichiro ,

[23478665] Maintenance of the hematopoietic stem cell pool in bone marrow niches by EVI1-regulated GPR56.

Saito Y , Kaneda K , Suekane A , Ichihara E , Nakahata S , Yamakawa N , Nagai K , Mizuno N , Kogawa K , Miura I , Itoh H , Morishita K ,

[23443806] Afatinib prolongs survival compared with gefitinib in an epidermal growth factor receptor-driven lung cancer model.

Ninomiya Takashi , Takigawa Nagio , Ichihara Eiki , Ochi Nobuaki , Murakami Toshi , Honda Yoshihiro , Kubo Toshio , Minami Daisuke , Kudo Kenichiro , Tanimoto Mitsune , Kiura Katsuyuki ,

[23291681] A definite case of (L)-carbocisteine-induced pneumonia with CATCH22 syndrome.

Kudo Kenichiro , Ichihara Eiki , Hisamoto Akiko , Hotta Katsuyuki , Miyahara Nobuaki , Tanimoto Yasushi , Akagi Sadaharu , Kato Katsuya , Tanimoto Mitsune , Kiura Katsuyuki ,

[23274758] Vandetanib is effective in EGFR-mutant lung cancer cells with PTEN deficiency.

Takeda Hiromasa , Takigawa Nagio , Ohashi Kadoaki , Minami Daisuke , Kataoka Itaru , Ichihara Eiki , Ochi Nobuaki , Tanimoto Mitsune , Kiura Katsuyuki ,

[23239809] Synergistic effect of olaparib with combination of cisplatin on PTEN-deficient lung cancer cells.

Minami Daisuke , Takigawa Nagio , Takeda Hiromasa , Takata Minoru , Ochi Nobuaki , Ichihara Eiki , Hisamoto Akiko , Hotta Katsuyuki , Tanimoto Mitsune , Kiura Katsuyuki ,

[23164554] Progression-free survival and overall survival in phase III trials of molecular-targeted agents in advanced non-small-cell lung cancer.

Hotta Katsuyuki , Suzuki Etsuji , Di Maio Massimo , Chiodini Paolo , Fujiwara Yoshiro , Takigawa Nagio , Ichihara Eiki , Reck Martin , Manegold Christian , Pilz Lothar , Hisamoto-Sato Akiko , Tabata Masahiro , Tanimoto Mitsune , Shepherd Frances A , Kiura Katsuyuki ,

[23066953] Subpopulation of small-cell lung cancer cells expressing CD133 and CD87 show resistance to chemotherapy.

Kubo Toshio , Takigawa Nagio , Osawa Masahiro , Harada Daijiro , Ninomiya Takashi , Ochi Nobuaki , Ichihara Eiki , Yamane Hiromichi , Tanimoto Mitsune , Kiura Katsuyuki ,

 

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