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Saura C 's Articles

[30377213] A RAD51 assay feasible in routine tumor samples calls PARP inhibitor response beyond BRCA mutation.

Castroviejo-Bermejo Marta , Cruz Cristina , Llop-Guevara Alba , Gutiérrez-Enríquez Sara , Ducy Mandy , Ibrahim Yasir Hussein , Gris-Oliver Albert , Pellegrino Benedetta , Bruna Alejandra , Guzmán Marta , Rodríguez Olga , Grueso Judit , Bonache Sandra , Moles-Fernández Alejandro , Villacampa Guillermo , Viaplana Cristina , Gómez Patricia , Vidal Marc , Peg Vicente , Serres-Créixams Xavier , Dellaire Graham , Simard Jacques , Nuciforo Paolo , Rubio Isabel T , Dientsmann Rodrigo , Barrett J Carl , Caldas Carlos , Baselga José , Saura Cristina , Cortés Javier , Déas Olivier , Jonkers Jos , Masson Jean-Yves , Cairo Stefano , Judde Jean-Gabriel , O'Connor Mark J , Díez Orland , Balmaña Judith , Serra Violeta ,

[30319324] From Standard of Care to the Neoadjuvant Model as an Innovative Platform for Exploring Promising Combinations in Breast Cancer.

Saura Cristina ,

[30282693] p95HER2-T cell bispecific antibody for breast cancer treatment.

Rius Ruiz Irene , Vicario Rocio , Morancho Beatriz , Morales Cristina Bernadó , Arenas Enrique J , Herter Sylvia , Freimoser-Grundschober Anne , Somandin Jitka , Sam Johannes , Ast Oliver , Barriocanal Águeda Martinez , Luque Antonio , Escorihuela Marta , Varela Ismael , Cuartas Isabel , Nuciforo Paolo , Fasani Roberta , Peg Vicente , Rubio Isabel , Cortés Javier , Serra Violeta , Escriva-de-Romani Santiago , Sperinde Jeff , Chenna Ahmed , Huang Weidong , Winslow John , Albanell Joan , Seoane Joan , Scaltriti Maurizio , Baselga Jose , Tabernero Josep , Umana Pablo , Bacac Marina , Saura Cristina , Klein Christian , Arribas Joaquín ,

[30233307] -Methyl-D-Aspartate Receptor Link to the MAP Kinase Pathway in Cortical and Hippocampal Neurons and Microglia Is Dependent on Calcium Sensors and Is Blocked by α-Synuclein, Tau, and Phospho-Tau in Non-transgenic and Transgenic APP Mice.

Franco Rafael , Aguinaga David , Reyes Irene , Canela Enric I , Lillo Jaume , Tarutani Airi , Hasegawa Masato , Del Ser-Badia Anna , Del Rio José A , Kreutz Michael R , Saura Carlos A , Navarro Gemma ,

[29870711] Molecular and functional interaction between GPR18 and cannabinoid CB G-protein-coupled receptors. Relevance in neurodegenerative diseases.

Reyes-Resina Irene , Navarro Gemma , Aguinaga David , Canela Enric I , Schoeder Clara T , Załuski Michał , Kieć-Kononowicz Katarzyna , Saura Carlos A , Müller Christa E , Franco Rafael ,

[29793946] Phase II Study of Taselisib (GDC-0032) in Combination with Fulvestrant in Patients with HER2-Negative, Hormone Receptor-Positive Advanced Breast Cancer.

Dickler Maura N , Saura Cristina , Richards Donald A , Krop Ian E , Cervantes Andrés , Bedard Philippe L , Patel Manish R , Pusztai Lajos , Oliveira Mafalda , Cardenas Alison K , Cui Na , Wilson Timothy R , Stout Thomas J , Wei Michael C , Hsu Jerry Y , Baselga José ,

[29755676] Genetic heterogeneity and actionable mutations in HER2-positive primary breast cancers and their brain metastases.

De Mattos-Arruda Leticia , Ng Charlotte K Y , Piscuoglio Salvatore , Gonzalez-Cao Maria , Lim Raymond S , De Filippo Maria R , Fusco Nicola , Schultheis Anne M , Ortiz Carolina , Viteri Santiago , Arias Alexandra , Macedo Gabriel S , Oliveira Mafalda , Gomez Patricia , Teixidó Cristina , Nuciforo Paolo , Peg Vicente , Saura Cristina , Ramon Y Cajal Santiago , Casas Francesc Tresserra , Weigelt Britta , Cortes Javier , Seoane Joan , Reis-Filho Jorge S ,

[29718117] Capturing intra-tumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: a proof-of-principle.

Mattos-Arruda L De , Weigelt B , Cortes J , Won H H , Ng C K Y , Nuciforo P , Bidard F-C , Aura C , Saura C , Peg V , Piscuoglio S , Oliveira M , Smolders Y , Patel P , Norton L , Tabernero J , Berger M F , Seoane J , Reis-Filho J S ,

[29691439] Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice.

Van der Jeugd Ann , Parra-Damas Arnaldo , Baeta-Corral Raquel , Soto-Faguás Carlos M , Ahmed Tariq , LaFerla Frank M , Giménez-Llort Lydia , D'Hooge Rudi , Saura Carlos A ,

[29674681] Publisher Correction: MSK1 regulates luminal cell differentiation and metastatic dormancy in ER breast cancer.

Gawrzak Sylwia , Rinaldi Lorenzo , Gregorio Sara , Arenas Enrique J , Salvador Fernando , Urosevic Jelena , Figueras-Puig Cristina , Rojo Federico , Del Barco Barrantes Ivan , Cejalvo Juan Miguel , Palafox Marta , Guiu Marc , Berenguer-Llergo Antonio , Symeonidi Aikaterini , Bellmunt Anna , Kalafatovic Daniela , Arnal-Estapé Anna , Fernández Esther , Müllauer Barbara , Groeneveld Rianne , Slobodnyuk Konstantin , Stephan-Otto Attolini Camille , Saura Cristina , Arribas Joaquín , Cortes Javier , Rovira Ana , Muñoz Montse , Lluch Ana , Serra Violeta , Albanell Joan , Prat Aleix , Nebreda Angel R , Benitah Salvador Aznar , Gomis Roger R ,

[29635390] RAD51 foci as a functional biomarker of homologous recombination repair and PARP inhibitor resistance in germline BRCA-mutated breast cancer.

Cruz C , Castroviejo-Bermejo M , Gutiérrez-Enríquez S , Llop-Guevara A , Ibrahim Y H , Gris-Oliver A , Bonache S , Morancho B , Bruna A , Rueda O M , Lai Z , Polanska U M , Jones G N , Kristel P , de Bustos L , Guzman M , Rodríguez O , Grueso J , Montalban G , Caratú G , Mancuso F , Fasani R , Jiménez J , Howat W J , Dougherty B , Vivancos A , Nuciforo P , Serres-Créixams X , Rubio I T , Oaknin A , Cadogan E , Barrett J C , Caldas C , Baselga J , Saura C , Cortés J , Arribas J , Jonkers J , Díez O , O'Connor M J , Balmaña J , Serra V ,

[29631097] HER2-positive breast cancer: Current and new therapeutic strategies.

Escrivá-de-Romaní Santiago , Arumí Miriam , Bellet Meritxell , Saura Cristina ,

[29420467] HER kinase inhibition in patients with HER2- and HER3-mutant cancers.

Hyman David M , Piha-Paul Sarina A , Won Helen , Rodon Jordi , Saura Cristina , Shapiro Geoffrey I , Juric Dejan , Quinn David I , Moreno Victor , Doger Bernard , Mayer Ingrid A , Boni Valentina , Calvo Emiliano , Loi Sherene , Lockhart Albert C , Erinjeri Joseph P , Scaltriti Maurizio , Ulaner Gary A , Patel Juber , Tang Jiabin , Beer Hannah , Selcuklu S Duygu , Hanrahan Aphrothiti J , Bouvier Nancy , Melcer Myra , Murali Rajmohan , Schram Alison M , Smyth Lillian M , Jhaveri Komal , Li Bob T , Drilon Alexander , Harding James J , Iyer Gopa , Taylor Barry S , Berger Michael F , Cutler Richard E , Xu Feng , Butturini Anna , Eli Lisa D , Mann Grace , Farrell Cynthia , Lalani Alshad S , Bryce Richard P , Arteaga Carlos L , Meric-Bernstam Funda , Baselga José , Solit David B ,

[29358704] MSK1 regulates luminal cell differentiation and metastatic dormancy in ER breast cancer.

Gawrzak Sylwia , Rinaldi Lorenzo , Gregorio Sara , Arenas Enrique J , Salvador Fernando , Urosevic Jelena , Figueras-Puig Cristina , Rojo Federico , Del Barco Barrantes Ivan , Cejalvo Juan Miguel , Palafox Marta , Guiu Marc , Berenguer-Llergo Antonio , Symeonidi Aikaterini , Bellmunt Anna , Kalafatovic Daniela , Arnal-Estapé Anna , Fernández Esther , Müllauer Barbara , Groeneveld Rianne , Slobodnyuk Konstantin , Stephan-Otto Attolini Camille , Saura Cristina , Arribas Joaquín , Cortes Javier , Rovira Ana , Muñoz Montse , Lluch Ana , Serra Violeta , Albanell Joan , Prat Aleix , Nebreda Angel R , Benitah Salvador Aznar , Gomis Roger R ,

[29269871] CRTC1 mediates preferential transcription at neuronal activity-regulated CRE/TATA promoters.

Parra-Damas Arnaldo , Rubió-Ferrarons Laura , Shen Jie , Saura Carlos A ,

[29229705] Proteolytic Processing of Neurexins by Presenilins Sustains Synaptic Vesicle Release.

Servián-Morilla Emilia , Robles-Lanuza Estefanía , Sánchez-Hidalgo Ana C , Camacho-Garcia Rafael J , Paez-Gomez Juan A , Mavillard Fabiola , Saura Carlos A , Martinez-Mir Amalia , Scholl Francisco G ,

[29198055] Phase II study of buparlisib (BKM120) and trastuzumab in patients with HER2+ locally advanced or metastatic breast cancer resistant to trastuzumab-based therapy.

Pistilli B , Pluard T , Urruticoechea A , Farci D , Kong A , Bachelot T , Chan S , Han H S , Jerusalem G , Urban P , Robinson D , Mouhaër S L , Tomaso E D , Massacesi C , Saura C ,

[29097017] Emerging Roles of CREB-Regulated Transcription Coactivators in Brain Physiology and Pathology.

Saura Carlos A , Cardinaux Jean-René ,

[28945947] Suspended Silicon Microphotodiodes for Electrochemical and Biological Applications.

Vargas-Estevez Carolina , Duch Marta , Duque Marcos , Del Campo Francisco Javier , Enriquez-Barreto Lilian , Murillo Gonzalo , Torras Núria , Plaza José A , Saura Carlos A , Esteve Jaume ,

[28843453] Receptor-heteromer mediated regulation of endocannabinoid signaling in activated microglia. Role of CB and CB receptors and relevance for Alzheimer's disease and levodopa-induced dyskinesia.

Navarro Gemma , Borroto-Escuela Dasiel , Angelats Edgar , Etayo Íñigo , Reyes-Resina Irene , Pulido-Salgado Marta , Rodríguez-Pérez Ana I , Canela Enric I , Saura Josep , Lanciego José Luis , Labandeira-García José Luis , Saura Carlos A , Fuxe Kjell , Franco Rafael ,

[28800861] Ipatasertib plus paclitaxel versus placebo plus paclitaxel as first-line therapy for metastatic triple-negative breast cancer (LOTUS): a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial.

Kim Sung-Bae , Dent Rebecca , Im Seock-Ah , Espié Marc , Blau Sibel , Tan Antoinette R , Isakoff Steven J , Oliveira Mafalda , Saura Cristina , Wongchenko Matthew J , Kapp Amy V , Chan Wai Y , Singel Stina M , Maslyar Daniel J , Baselga José , ,

[27872130] A First-in-Human Phase I Study of the ATP-Competitive AKT Inhibitor Ipatasertib Demonstrates Robust and Safe Targeting of AKT in Patients with Solid Tumors.

Saura Cristina , Roda Desamparados , Roselló Susana , Oliveira Mafalda , Macarulla Teresa , Pérez-Fidalgo José Alejandro , Morales-Barrera Rafael , Sanchis-García Juan Manuel , Musib Luna , Budha Nageshwar , Zhu Jin , Nannini Michelle , Chan Wai Y , Sanabria Bohórquez Sandra M , Meng Raymond D , Lin Kui , Yan Yibing , Patel Premal , Baselga José , Tabernero Josep , Cervantes Andrés ,

[27587263] CRTC1 Function During Memory Encoding Is Disrupted in Neurodegeneration.

Parra-Damas Arnaldo , Chen Meng , Enriquez-Barreto Lilian , Ortega Laura , Acosta Sara , Perna Judith Camats , Fullana M Neus , Aguilera José , Rodríguez-Alvarez José , Saura Carlos A ,

[27498054] Preservation of cell-survival mechanisms by the presenilin-1 K239N mutation may cause its milder clinical phenotype.

Sarroca Sara , Molina-Martínez Patricia , Aresté Cristina , Etzrodt Martin , García de Frutos Pablo , Gasa Rosa , Antonell Anna , Molinuevo José Luís , Sánchez-Valle Raquel , Saura Carlos A , Lladó Albert , Sanfeliu Coral ,

[27093617] Menopause status is associated with circadian- and sleep-related alterations.

Gómez-Santos Cecilia , Saura Cristina Bandín , Lucas J A Ros , Castell Pedro , Madrid Juan A , Garaulet Marta ,

[26683474] SEOM clinical guidelines in metastatic breast cancer 2015.

Gavilá J , Lopez-Tarruella S , Saura C , Muñoz M , Oliveira M , De la Cruz-Merino L , Morales S , Alvarez I , Virizuela J A , Martin M ,

[26379494] Gene expression parallels synaptic excitability and plasticity changes in Alzheimer's disease.

Saura Carlos A , Parra-Damas Arnaldo , Enriquez-Barreto Lilian ,

[25537644] Phase I/II study of pilaralisib (SAR245408) in combination with trastuzumab or trastuzumab plus paclitaxel in trastuzumab-refractory HER2-positive metastatic breast cancer.

Tolaney Sara , Burris Howard , Gartner Elaina , Mayer Ingrid A , Saura Cristina , Maurer Matthew , Ciruelos Eva , Garcia Agustin A , Campana Frank , Wu Bin , Xu Yi , Jiang Jason , Winer Eric , Krop Ian ,

[25287822] Safety and efficacy of neratinib in combination with capecitabine in patients with metastatic human epidermal growth factor receptor 2-positive breast cancer.

Saura Cristina , Garcia-Saenz Jose A , Xu Binghe , Harb Wael , Moroose Rebecca , Pluard Timothy , Cortés Javier , Kiger Corinne , Germa Caroline , Wang Kongming , Martin Miguel , Baselga José , Kim Sung-Bae ,

[25009010] Capturing intra-tumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: a proof-of-principle.

De Mattos-Arruda L , Weigelt B , Cortes J , Won H H , Ng C K Y , Nuciforo P , Bidard F-C , Aura C , Saura C , Peg V , Piscuoglio S , Oliveira M , Smolders Y , Patel P , Norton L , Tabernero J , Berger M F , Seoane J , Reis-Filho J S ,

[24827126] Phase I trial of olaparib in combination with cisplatin for the treatment of patients with advanced breast, ovarian and other solid tumors.

Balmaña J , Tung N M , Isakoff S J , Graña B , Ryan P D , Saura C , Lowe E S , Frewer P , Winer E , Baselga J , Garber J E ,

[24760838] Crtc1 activates a transcriptional program deregulated at early Alzheimer's disease-related stages.

Parra-Damas Arnaldo , Valero Jorge , Chen Meng , España Judit , Martín Elsa , Ferrer Isidro , Rodríguez-Alvarez José , Saura Carlos A ,

[24523415] Ras protein activation is a key event in activity-dependent survival of cerebellar granule neurons.

Xifró Xavier , Miñano-Molina Alfredo J , Saura Carlos A , Rodríguez-Álvarez José ,

[24470511] Phase Ib study of Buparlisib plus Trastuzumab in patients with HER2-positive advanced or metastatic breast cancer that has progressed on Trastuzumab-based therapy.

Saura Cristina , Bendell Johanna , Jerusalem Guy , Su Shaun , Ru Qinhua , De Buck Stefan , Mills David , Ruquet Sophie , Bosch Ana , Urruticoechea Ander , Beck Joseph T , Di Tomaso Emmanuelle , Sternberg David W , Massacesi Cristian , Hirawat Samit , Dirix Luc , Baselga Jose ,

[24344333] ApoER2 processing by presenilin-1 modulates reelin expression.

Balmaceda Valeria , Cuchillo-Ibáñez Inmaculada , Pujadas Lluis , García-Ayllón María-Salud , Saura Carlos A , Nimpf Johannes , Soriano Eduardo , Sáez-Valero Javier ,

[24252417] CSF Presenilin-1 complexes are increased in Alzheimer's disease.

García-Ayllón María-Salud , Campanari María-Letizia , Brinkmalm Gunnar , Rábano Alberto , Alom Jordi , Saura Carlos A , Andreasen Niels , Blennow Kaj , Sáez-Valero Javier ,

[24141624] Evaluation and clinical analyses of downstream targets of the Akt inhibitor GDC-0068.

Yan Yibing , Serra Violeta , Prudkin Ludmila , Scaltriti Maurizio , Murli Sumati , Rodríguez Olga , Guzman Marta , Sampath Deepak , Nannini Michelle , Xiao Yuanyuan , Wagle Marie-Claire , Wu Jenny Q , Wongchenko Matthew , Hampton Garret , Ramakrishnan Vanitha , Lackner Mark R , Saura Cristina , Roda Desamparados , Cervantes Andrés , Tabernero Josep , Patel Premal , Baselga José ,

[23928917] X-linked inhibitor of apoptosis protein negatively regulates neuronal differentiation through interaction with cRAF and Trk.

Fadó Rut , Moubarak Rana S , Miñano-Molina Alfredo J , Barneda-Zahonero Bruna , Valero Jorge , Saura Carlos A , Moran Julio , Comella Joan X , Rodríguez-Álvarez José ,

[23853246] Neoadjuvant doxorubicin/cyclophosphamide followed by ixabepilone or paclitaxel in early stage breast cancer and evaluation of βIII-tubulin expression as a predictive marker.

Saura Cristina , Tseng Ling-Ming , Chan Stephen , Chacko Raju T , Campone Mario , Manikhas Alexy , Nag Shona M , Leichman Cynthia G , Dasappa Lokanatha , Fasching Peter A , Hurtado de Mendoza Fernando , Symmans W Fraser , Liu David , Mukhopadhyay Pralay , Horak Christine , Xing Guan , Pusztai Lajos ,

[23787161] First cases of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infections in France, investigations and implications for the prevention of human-to-human transmission, France, May 2013.

Mailles A , Blanckaert K , Chaud P , van der Werf S , Lina B , Caro V , Campese C , Guéry B , Prouvost H , Lemaire X , Paty M C , Haeghebaert S , Antoine D , Ettahar N , Noel H , Behillil S , Hendricx S , Manuguerra J C , Enouf V , La Ruche G , Semaille Caroline , Coignard B , Lévy-Bruhl D , Weber F , Saura C , Che D , ,

[23580070] A multicenter trial evaluating retaspimycin HCL (IPI-504) plus trastuzumab in patients with advanced or metastatic HER2-positive breast cancer.

Modi Shanu , Saura Cristina , Henderson Charles , Lin Nancy U , Mahtani Reshma , Goddard Jill , Rodenas Eduardo , Hudis Clifford , O'Shaughnessy Joyce , Baselga Jose ,

[23340299] Biomarker analysis of neoadjuvant doxorubicin/cyclophosphamide followed by ixabepilone or Paclitaxel in early-stage breast cancer.

Horak Christine E , Pusztai Lajos , Xing Guan , Trifan Ovidiu C , Saura Cristina , Tseng Ling-Ming , Chan Stephen , Welcher Rosanne , Liu David ,

[23165977] Management of the axilla in early breast cancer patients in the genomic era.

Oliveira M , Cortés J , Bellet M , Balmaña J , De Mattos-Arruda L , Gómez P , Muñoz E , Ortega V , Pérez J , Saura C , Vidal M , Rubio I T , Di Cosimo S ,

[23137566] Implication of breast cancer phenotype for patients with leptomeningeal carcinomatosis.

Torrejón Davis , Oliveira Mafalda , Cortes Javier , Sanchez-Olle Gessami , Gómez Patricia , Bellet Meritxell , Saura Cristina , Peg Vicente , Rovira Alex , Di Cosimo Serena ,

[23116970] Multidisciplinary approach to breast cancer diagnosed during pregnancy: maternal and neonatal outcomes.

Córdoba Octavi , Llurba Elisa , Saura Cristina , Rubio Isabel , Ferrer Queralt , Cortés Javier , Xercavins Jordi ,

[22723336] Molecular profiling of patients with colorectal cancer and matched targeted therapy in phase I clinical trials.

Dienstmann Rodrigo , Serpico Danila , Rodon Jordi , Saura Cristina , Macarulla Teresa , Elez Elena , Alsina Maria , Capdevila Jaume , Perez-Garcia Jose , Sánchez-Ollé Gessamí , Aura Claudia , Prudkin Ludmila , Landolfi Stefania , Hernández-Losa Javier , Vivancos Ana , Tabernero Josep ,

[22593004] ATP and noradrenaline activate CREB in astrocytes via noncanonical Ca(2+) and cyclic AMP independent pathways.

Carriba Paulina , Pardo Luis , Parra-Damas Arnaldo , Lichtenstein Mathieu P , Saura Carlos A , Pujol Aurora , Masgrau Roser , Galea Elena ,

[22473105] Molecular prescreening to select patient population in early clinical trials.

Rodón Jordi , Saura Cristina , Dienstmann Rodrigo , Vivancos Ana , Ramón y Cajal Santiago , Baselga José , Tabernero Josep ,

[22294685] Nurr1 protein is required for N-methyl-D-aspartic acid (NMDA) receptor-mediated neuronal survival.

Barneda-Zahonero Bruna , Servitja Joan-Marc , Badiola Nahuai , Miñano-Molina Alfredo J , Fadó Rut , Saura Carlos A , Rodríguez-Alvarez José ,

[22236576] CREB-regulated transcription coactivator 1-dependent transcription in Alzheimer's disease mice.

Saura Carlos A ,

 

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