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16.1 kDa protein (E3 16.1 kDa protein) (Membrane glycoprotein E3 CR1-alpha)

 Q9PWV0_ADE07            Unreviewed;       146 AA.
Q9PWV0;
01-MAY-2000, integrated into UniProtKB/TrEMBL.
01-MAY-2000, sequence version 1.
20-JUN-2018, entry version 53.
SubName: Full=E3 16.1 kDa protein {ECO:0000313|EMBL:AAT97594.1};
SubName: Full=Membrane glycoprotein E3 CR1-alpha {ECO:0000313|EMBL:AGZ15342.1};
Name=E3 {ECO:0000313|EMBL:AAR89968.1};
Human adenovirus B serotype 7 (HAdV-7) (Human adenovirus 7).
Viruses; dsDNA viruses, no RNA stage; Adenoviridae; Mastadenovirus;
Human mastadenovirus B.
NCBI_TaxID=10519 {ECO:0000313|EMBL:AAF14140.1};
NCBI_TaxID=9606; Homo sapiens (Human).
[1] {ECO:0000313|EMBL:AAF14140.1}
NUCLEOTIDE SEQUENCE.
STRAIN=Bal {ECO:0000313|EMBL:AAF14140.1};
Inada T., Mukoyama A., Yamadera S., Hashido M., Inoue S.;
"Epidemiology and genomic analysis of hexon, fiber and E3 region genes
of adenovirus type 7 in Japan.";
Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|EMBL:AAR89968.1}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Vaccine strain {ECO:0000313|EMBL:AAR89968.1};
Jiang X., Wang J., Huang T.;
Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
[3] {ECO:0000313|EMBL:AAT97594.1, ECO:0000313|Proteomes:UP000133920}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=16000418; DOI=10.1128/JCM.43.7.3083-3094.2005;
Purkayastha A., Su J., McGraw J., Ditty S.E., Hadfield T.L., Seto J.,
Russell K.L., Tibbetts C., Seto D.;
"Genomic and bioinformatics analyses of HAdV-4vac and HAdV-7vac, two
human adenovirus (HAdV) strains that constituted original prophylaxis
against HAdV-related acute respiratory disease, a reemerging epidemic
disease.";
J. Clin. Microbiol. 43:3083-3094(2005).
[4] {ECO:0000313|EMBL:AAW33409.1, ECO:0000313|Proteomes:UP000119312}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=NHRC 1315 {ECO:0000313|EMBL:AAW33409.1};
PubMed=16481660; DOI=10.1101/gr.4337206;
Lin B., Wang Z., Vora G.J., Thornton J.A., Schnur J.M., Thach D.C.,
Blaney K.M., Ligler A.G., Malanoski A.P., Santiago J., Walter E.A.,
Agan B.K., Metzgar D., Seto D., Daum L.T., Kruzelock R., Rowley R.K.,
Hanson E.H., Tibbetts C., Stenger D.A.;
"Broad-spectrum respiratory tract pathogen identification using
resequencing DNA microarrays.";
Genome Res. 16:527-535(2006).
[5] {ECO:0000313|EMBL:AFV96299.1, ECO:0000313|Proteomes:UP000173062}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CQ1198 {ECO:0000313|EMBL:AFV96299.1};
Ni K., He L.L., Xu Z.F., Peng C.J., Liu E.M.;
"Mutant HAdV-7d2 Strain was Identified from Children with Severe
Respiratory Infection in Southwestern China.";
Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
[6] {ECO:0000313|EMBL:AFI24594.1, ECO:0000313|Proteomes:UP000169742}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=0901HZ/ShX/CHN/2009 {ECO:0000313|EMBL:AFI24594.1};
PubMed=23409258;
Tang L., An J., Yu P., Xu W.;
"Complete genome sequence of human adenovirus type 7 associated with
fatal infant pneumonia.";
Genome Announc. 1:E00182-12(2013).
[7] {ECO:0000313|EMBL:AHJ81837.1, ECO:0000313|Proteomes:UP000145850}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=HAdV B7 XZ2011-93 {ECO:0000313|EMBL:AHJ81837.1};
Tang L., Yang J., Tong J., Zhang L.;
"Genome and bioinformatic analysis of an HAdV-B7 virus in Jiangsu,
China.";
Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
[8] {ECO:0000313|EMBL:AGZ15342.1, ECO:0000313|Proteomes:UP000120913}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Human/CHN/DG01/2011/7[P7H7F7] {ECO:0000313|EMBL:AGZ15342.1};
PubMed=25482188; DOI=10.1038/srep07365;
Zhao S., Wan C., Ke C., Seto J., Dehghan S., Zou L., Zhou J.,
Cheng Z., Jing S., Zeng Z., Zhang J., Wan X., Wu X., Zhao W., Zhu L.,
Seto D., Zhang Q.;
"Re-emergent Human Adenovirus Genome Type 7d Caused an Acute
Respiratory Disease Outbreak in Southern China After a Twenty-one Year
Absence.";
Sci. Rep. 4:7365-7365(2014).
[9] {ECO:0000313|EMBL:AIY53503.1, ECO:0000313|Proteomes:UP000120727}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CDC228/JM/CHN/2012 {ECO:0000313|EMBL:AIY53503.1};
PubMed=26338697; DOI=10.1038/srep13617;
Qiu S., Li P., Liu H., Wang Y., Liu N., Li C., Li S., Li M., Jiang Z.,
Sun H., Li Y., Xie J., Yang C., Wang J., Li H., Yi S., Wu Z., Jia L.,
Wang L., Hao R., Sun Y., Huang L., Ma H., Yuan Z., Song H.;
"Whole-genome Sequencing for Tracing the Transmission Link between Two
ARD Outbreaks Caused by a Novel HAdV Serotype 7 Variant, China.";
Sci. Rep. 5:13617-13617(2015).
[10] {ECO:0000313|Proteomes:UP000099968, ECO:0000313|Proteomes:UP000138206, ECO:0000313|Proteomes:UP000143275}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Yu Z., Zhang Q., Fu N.;
"Fatal Pediatric Respiratory Infection Caused by Human Adenovirus
Genotype 7d in Guangzhou, China, 2010-2012.";
Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
[11] {ECO:0000313|EMBL:ANP92022.1, ECO:0000313|Proteomes:UP000140963}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=19BOVLB/Volgograd/Rus/2014 {ECO:0000313|EMBL:ANP92022.1};
Yatsyshina S.B., Ageeva M.R., Pimkina E.V., Deviatkin A.A.,
Markelov M.L., Dedkov V.G., Safonova M.V.;
"Complete genome sequence of human adenovirus type 7 associated with
fatal adult pneumonia.";
Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
[12] {ECO:0000313|EMBL:ANI70158.1, ECO:0000313|Proteomes:UP000098519}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CDC 2014012.949 {ECO:0000313|EMBL:ANI70158.1};
PubMed=27191834; DOI=10.3201/eid2206.151898;
Scott M.K., Chommanard C., Lu X., Appelgate D., Grenz L.,
Schneider E., Gerber S.I., Erdman D.D., Thomas A.;
"Human Adenovirus Associated with Severe Respiratory Infection,
Oregon, USA, 2013-2014.";
Emerg. Infect. Dis. 22:1044-1051(2016).
[13] {ECO:0000313|EMBL:AKQ24933.1}
NUCLEOTIDE SEQUENCE.
STRAIN=Human/CHN/GZ6080/2010/7[P7H7F7] {ECO:0000313|EMBL:AKQ25050.1},
Human/CHN/GZ6784/2011/7[P7H7F7] {ECO:0000313|EMBL:AKQ25011.1},
Human/CHN/GZ6965/2011/7[P7H7F7] {ECO:0000313|EMBL:AKQ24972.1},
Human/CHN/GZ7015/2011/7[P7H7F7] {ECO:0000313|EMBL:AKQ24933.1},
Human/CHN/GZ7052/2011/7[P7H7F7] {ECO:0000313|EMBL:AKQ25167.1},
Human/CHN/GZ8546/2012/7[P7H7F7] {ECO:0000313|EMBL:AKQ25128.1}, and
Human/CHN/GZ8987/2012/7[P7H7F7] {ECO:0000313|EMBL:AKQ25089.1};
PubMed=27848998; DOI=.1038/srep37216;
Yu Z., Zeng Z., Zhang J., Pan Y., Chen M., Guo Y., Yu N., Chodosh J.,
Fu N., Che X., Zhang Q.;
"Fatal Community-acquired Pneumonia in Children Caused by Re-emergent
Human Adenovirus 7d Associated with Higher Severity of Illness and
Fatality Rate.";
Sci. Rep. 6:37216-37216(2016).
[14] {ECO:0000313|Proteomes:UP000119758, ECO:0000313|Proteomes:UP000160399}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Yu Z., Zhang Q., Fu N.;
"Fatal Pediatric Respiratory Infection Caused by Human Adenovirus
Genotype 7d in Guangzhou, China, 2010-2012.";
Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
[15] {ECO:0000313|EMBL:ASK85785.1}
NUCLEOTIDE SEQUENCE.
STRAIN=Z9/WH/CHN/2015 complete genome {ECO:0000313|EMBL:ASK85785.1};
PubMed=28225804;
Yang X., Wang Q., Liang B., Wu F., Li H., Liu H., Sheng C., Ma Q.,
Yang C., Xie J., Li P., Jia L., Wang L., Du X., Qiu S., Song H.;
"An outbreak of acute respiratory disease caused by a virus associated
RNA II gene mutation strain of human adenovirus 7 in China, 2015.";
PLoS ONE 12:E0172519-E0172519(2017).
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EMBL; AF104384; AAF14140.1; -; Genomic_DNA.
EMBL; AY495969; AAR89968.1; -; Genomic_DNA.
EMBL; AY594256; AAT97594.1; -; Genomic_DNA.
EMBL; AY601634; AAW33409.1; -; Genomic_DNA.
EMBL; JF800905; AFI24594.1; -; Genomic_DNA.
EMBL; JX625134; AFV96299.1; -; Genomic_DNA.
EMBL; KC440171; AGZ15342.1; -; Genomic_DNA.
EMBL; KC857700; AHJ81837.1; -; Genomic_DNA.
EMBL; KJ019884; AIY53503.1; -; Genomic_DNA.
EMBL; KP670855; AKQ24933.1; -; Genomic_DNA.
EMBL; KP670856; AKQ24972.1; -; Genomic_DNA.
EMBL; KP670857; AKQ25011.1; -; Genomic_DNA.
EMBL; KP670858; AKQ25050.1; -; Genomic_DNA.
EMBL; KP670859; AKQ25089.1; -; Genomic_DNA.
EMBL; KP670860; AKQ25128.1; -; Genomic_DNA.
EMBL; KP670861; AKQ25167.1; -; Genomic_DNA.
EMBL; KT963081; ANI70158.1; -; Genomic_DNA.
EMBL; KU361344; ANP92022.1; -; Genomic_DNA.
EMBL; KX897164; ASK85785.1; -; Genomic_DNA.
RefSeq; AP_000556.1; AC_000018.1.
Proteomes; UP000098519; Genome.
Proteomes; UP000099968; Genome.
Proteomes; UP000119312; Genome.
Proteomes; UP000119758; Genome.
Proteomes; UP000120727; Genome.
Proteomes; UP000120913; Genome.
Proteomes; UP000133920; Genome.
Proteomes; UP000138206; Genome.
Proteomes; UP000140963; Genome.
Proteomes; UP000143275; Genome.
Proteomes; UP000145850; Genome.
Proteomes; UP000151122; Genome.
Proteomes; UP000160399; Genome.
Proteomes; UP000169742; Genome.
Proteomes; UP000172553; Genome.
Proteomes; UP000173062; Genome.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
InterPro; IPR009266; Adeno_E3.
Pfam; PF06040; Adeno_E3; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000120727};
Membrane {ECO:0000256|SAM:Phobius};
Reference proteome {ECO:0000313|Proteomes:UP000120727};
Transmembrane {ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAM:Phobius}.
TRANSMEM 103 136 Helical. {ECO:0000256|SAM:Phobius}.
SEQUENCE 146 AA; 16064 MW; E1BE4DCE6D3B14A8 CRC64;
MKAFAVLFVL SLIKTELRPS YGLPLLQSGL YNTNQIFQKT QTLPPLIQDS NSTLPAPSTT
NLPETNKLGS HLQHRLSRSL LSANTTTPKT GGELRGLPTD DPWVVAGFVT LGVVAGGLVL
ILCYLYIPCC AYLVILRCWF KKWGPY


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