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19 kDa MHC class I antigen-binding glycoprotein (19.3 kDa MHC class I antigen-binding glycoprotein) (19.3 kDa MHC class I antigen-binding protein) (19.3 kDa glycoprotein) (19.3 kDa protein) (E3 18.3 kDa glycoprotein) (E3 19.3 kDa MHC class I antigen-binding glycoprotein) (E3 MHC class I antigen-binding glycoprotein) (ORF 19 kDa)

 Q77SK4_ADE07            Unreviewed;       172 AA.
Q77SK4; Q83126;
05-JUL-2004, integrated into UniProtKB/TrEMBL.
05-JUL-2004, sequence version 1.
07-NOV-2018, entry version 63.
SubName: Full=19 kDa MHC class I antigen-binding glycoprotein {ECO:0000313|EMBL:AAW33410.1};
SubName: Full=19.3 kDa MHC class I antigen-binding glycoprotein {ECO:0000313|EMBL:AGZ15343.1};
SubName: Full=19.3 kDa MHC class I antigen-binding protein {ECO:0000313|EMBL:ANI70159.1};
SubName: Full=19.3 kDa glycoprotein {ECO:0000313|EMBL:AAF14141.1};
SubName: Full=19.3 kDa protein {ECO:0000313|EMBL:AAR89969.1};
SubName: Full=E3 18.3 kDa glycoprotein {ECO:0000313|EMBL:AAT97595.1};
SubName: Full=E3 19.3 kDa MHC class I antigen-binding glycoprotein {ECO:0000313|EMBL:AAT97555.1};
SubName: Full=E3 MHC class I antigen-binding glycoprotein {ECO:0000313|EMBL:ACX32416.1};
SubName: Full=ORF 19 kDa {ECO:0000313|EMBL:CAA88805.1};
Name=E3 {ECO:0000313|EMBL:AAR89969.1};
Human adenovirus B serotype 7 (HAdV-7) (Human adenovirus 7).
Viruses; dsDNA viruses, no RNA stage; Adenoviridae; Mastadenovirus;
Human mastadenovirus B.
NCBI_TaxID=10519 {ECO:0000313|EMBL:AAF14141.1};
NCBI_TaxID=9606; Homo sapiens (Human).
[1] {ECO:0000313|EMBL:CAA88805.1}
NUCLEOTIDE SEQUENCE.
STRAIN=Gomen {ECO:0000313|EMBL:CAA88805.1};
PubMed=8560766; DOI=10.1006/viro.1996.0022;
Kajon A.E., Wadell G.;
"Sequence analysis of the E3 region and fiber gene of human adenovirus
genome type 7h.";
Virology 215:190-196(1996).
[2] {ECO:0000313|EMBL:AAF14141.1}
NUCLEOTIDE SEQUENCE.
STRAIN=Bal {ECO:0000313|EMBL:AAF14141.1};
Inada T., Mukoyama A., Yamadera S., Hashido M., Inoue S.;
"Epidemiology and genomic analysis of hexon, fiber and E3 region genes
of adenovirus type 7 in Japan.";
Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
[3] {ECO:0000313|EMBL:AAR89969.1}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Vaccine strain {ECO:0000313|EMBL:AAR89969.1};
Jiang X., Wang J., Huang T.;
Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
[4] {ECO:0000313|EMBL:AAT97595.1, ECO:0000313|Proteomes:UP000133920}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=16000418; DOI=10.1128/JCM.43.7.3083-3094.2005;
Purkayastha A., Su J., McGraw J., Ditty S.E., Hadfield T.L., Seto J.,
Russell K.L., Tibbetts C., Seto D.;
"Genomic and bioinformatics analyses of HAdV-4vac and HAdV-7vac, two
human adenovirus (HAdV) strains that constituted original prophylaxis
against HAdV-related acute respiratory disease, a reemerging epidemic
disease.";
J. Clin. Microbiol. 43:3083-3094(2005).
[5] {ECO:0000313|EMBL:AAT97555.1, ECO:0000313|Proteomes:UP000173900}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Gomen {ECO:0000313|EMBL:AAT97555.1};
PubMed=15661145; DOI=10.1016/j.virol.2004.10.041;
Purkayastha A., Su J., Carlisle S., Tibbetts C., Seto D.;
"Genomic and bioinformatics analysis of HAdV-7, a human adenovirus of
species B1 that causes acute respiratory disease: implications for
vector development in human gene therapy.";
Virology 332:114-129(2005).
[6] {ECO:0000313|EMBL:AAW33410.1, ECO:0000313|Proteomes:UP000119312}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=NHRC 1315 {ECO:0000313|EMBL:AAW33410.1};
PubMed=16481660; DOI=10.1101/gr.4337206;
Lin B., Wang Z., Vora G.J., Thornton J.A., Schnur J.M., Thach D.C.,
Blaney K.M., Ligler A.G., Malanoski A.P., Santiago J., Walter E.A.,
Agan B.K., Metzgar D., Seto D., Daum L.T., Kruzelock R., Rowley R.K.,
Hanson E.H., Tibbetts C., Stenger D.A.;
"Broad-spectrum respiratory tract pathogen identification using
resequencing DNA microarrays.";
Genome Res. 16:527-535(2006).
[7] {ECO:0000313|EMBL:ACX32416.1, ECO:0000313|Proteomes:UP000097917}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=GZ08 {ECO:0000313|EMBL:ACX32416.1};
PubMed=21740937; DOI=10.1016/j.virusres.2011.06.017;
Tian X., Su X., Li H., Li X., Zhou Z., Liu W., Zhou R.;
"Construction and characterization of human adenovirus serotype 3
packaged by serotype 7 hexon.";
Virus Res. 160:214-220(2011).
[8] {ECO:0000313|EMBL:AFV96300.1, ECO:0000313|Proteomes:UP000173062}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CQ1198 {ECO:0000313|EMBL:AFV96300.1};
Ni K., He L.L., Xu Z.F., Peng C.J., Liu E.M.;
"Mutant HAdV-7d2 Strain was Identified from Children with Severe
Respiratory Infection in Southwestern China.";
Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
[9] {ECO:0000313|EMBL:AFI24595.1, ECO:0000313|Proteomes:UP000169742}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=0901HZ/ShX/CHN/2009 {ECO:0000313|EMBL:AFI24595.1};
PubMed=23409258;
Tang L., An J., Yu P., Xu W.;
"Complete genome sequence of human adenovirus type 7 associated with
fatal infant pneumonia.";
Genome Announc. 1:E00182-12(2013).
[10] {ECO:0000313|EMBL:AHJ81838.1, ECO:0000313|Proteomes:UP000145850}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=HAdV B7 XZ2011-93 {ECO:0000313|EMBL:AHJ81838.1};
Tang L., Yang J., Tong J., Zhang L.;
"Genome and bioinformatic analysis of an HAdV-B7 virus in Jiangsu,
China.";
Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
[11] {ECO:0000313|EMBL:AGZ15343.1, ECO:0000313|Proteomes:UP000120913}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Human/CHN/DG01/2011/7[P7H7F7] {ECO:0000313|EMBL:AGZ15343.1};
PubMed=25482188; DOI=10.1038/srep07365;
Zhao S., Wan C., Ke C., Seto J., Dehghan S., Zou L., Zhou J.,
Cheng Z., Jing S., Zeng Z., Zhang J., Wan X., Wu X., Zhao W., Zhu L.,
Seto D., Zhang Q.;
"Re-emergent Human Adenovirus Genome Type 7d Caused an Acute
Respiratory Disease Outbreak in Southern China After a Twenty-one Year
Absence.";
Sci. Rep. 4:7365-7365(2014).
[12] {ECO:0000313|Proteomes:UP000102474, ECO:0000313|Proteomes:UP000107022, ECO:0000313|Proteomes:UP000109842}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CDC228/JM/CHN/2012 {ECO:0000313|EMBL:AIY53504.1},
H12/JM/CHN/2012 {ECO:0000313|EMBL:AIY53544.1},
H18/JM/CHN/2013 {ECO:0000313|EMBL:AIY53584.1},
JM11/JM/CHN/2013 {ECO:0000313|EMBL:AIY53624.1},
K22/JM/CHN/2013 {ECO:0000313|EMBL:AIY53464.1},
K57/JM/CHN/2012 {ECO:0000313|EMBL:AIY53424.1},
L14/XY/CHN/2012 {ECO:0000313|EMBL:AIY53664.1},
L34/XY/CHN/2012 {ECO:0000313|EMBL:AIY53384.1},
XY1/XY/CHN/2012 {ECO:0000313|EMBL:AIY53344.1}, and
XY6/XY/CHN/2013 {ECO:0000313|EMBL:AIY53304.1};
PubMed=26338697; DOI=10.1038/srep13617;
Qiu S., Li P., Liu H., Wang Y., Liu N., Li C., Li S., Li M., Jiang Z.,
Sun H., Li Y., Xie J., Yang C., Wang J., Li H., Yi S., Wu Z., Jia L.,
Wang L., Hao R., Sun Y., Huang L., Ma H., Yuan Z., Song H.;
"Whole-genome Sequencing for Tracing the Transmission Link between Two
ARD Outbreaks Caused by a Novel HAdV Serotype 7 Variant, China.";
Sci. Rep. 5:13617-13617(2015).
[13] {ECO:0000313|Proteomes:UP000099968, ECO:0000313|Proteomes:UP000138206, ECO:0000313|Proteomes:UP000143275}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Yu Z., Zhang Q., Fu N.;
"Fatal Pediatric Respiratory Infection Caused by Human Adenovirus
Genotype 7d in Guangzhou, China, 2010-2012.";
Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
[14] {ECO:0000313|EMBL:ANI70159.1, ECO:0000313|Proteomes:UP000098519}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CDC 2014012.949 {ECO:0000313|EMBL:ANI70159.1};
PubMed=27191834; DOI=10.3201/eid2206.151898;
Scott M.K., Chommanard C., Lu X., Appelgate D., Grenz L.,
Schneider E., Gerber S.I., Erdman D.D., Thomas A.;
"Human Adenovirus Associated with Severe Respiratory Infection,
Oregon, USA, 2013-2014.";
Emerg. Infect. Dis. 22:1044-1051(2016).
[15] {ECO:0000313|EMBL:AIY53304.1, ECO:0000313|Proteomes:UP000110534}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=XY6/XY/CHN/2013 {ECO:0000313|EMBL:AIY53304.1};
PubMed=26663527; DOI=10.1002/mbo3.321;
Kwon Y.M., Kim S.Y., Jung K.H., Kim S.J.;
"Diversity and functional analysis of light-driven pumping rhodopsins
in marine Flavobacteria.";
MicrobiologyOpen 5:212-223(2016).
[16] {ECO:0000313|EMBL:AKQ24934.1}
NUCLEOTIDE SEQUENCE.
STRAIN=Human/CHN/GZ6080/2010/7[P7H7F7] {ECO:0000313|EMBL:AKQ25051.1},
Human/CHN/GZ6784/2011/7[P7H7F7] {ECO:0000313|EMBL:AKQ25012.1},
Human/CHN/GZ6965/2011/7[P7H7F7] {ECO:0000313|EMBL:AKQ24973.1},
Human/CHN/GZ7015/2011/7[P7H7F7] {ECO:0000313|EMBL:AKQ24934.1},
Human/CHN/GZ7052/2011/7[P7H7F7] {ECO:0000313|EMBL:AKQ25168.1},
Human/CHN/GZ8546/2012/7[P7H7F7] {ECO:0000313|EMBL:AKQ25129.1}, and
Human/CHN/GZ8987/2012/7[P7H7F7] {ECO:0000313|EMBL:AKQ25090.1};
PubMed=27848998; DOI=.1038/srep37216;
Yu Z., Zeng Z., Zhang J., Pan Y., Chen M., Guo Y., Yu N., Chodosh J.,
Fu N., Che X., Zhang Q.;
"Fatal Community-acquired Pneumonia in Children Caused by Re-emergent
Human Adenovirus 7d Associated with Higher Severity of Illness and
Fatality Rate.";
Sci. Rep. 6:37216-37216(2016).
[17] {ECO:0000313|Proteomes:UP000119758, ECO:0000313|Proteomes:UP000160399}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Yu Z., Zhang Q., Fu N.;
"Fatal Pediatric Respiratory Infection Caused by Human Adenovirus
Genotype 7d in Guangzhou, China, 2010-2012.";
Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
[18] {ECO:0000313|EMBL:ASK85786.1}
NUCLEOTIDE SEQUENCE.
STRAIN=Z9/WH/CHN/2015 complete genome {ECO:0000313|EMBL:ASK85786.1};
PubMed=28225804;
Yang X., Wang Q., Liang B., Wu F., Li H., Liu H., Sheng C., Ma Q.,
Yang C., Xie J., Li P., Jia L., Wang L., Du X., Qiu S., Song H.;
"An outbreak of acute respiratory disease caused by a virus associated
RNA II gene mutation strain of human adenovirus 7 in China, 2015.";
PLoS ONE 12:E0172519-E0172519(2017).
-----------------------------------------------------------------------
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EMBL; AF104384; AAF14141.1; -; Genomic_DNA.
EMBL; AY495969; AAR89969.1; -; Genomic_DNA.
EMBL; AY594255; AAT97555.1; -; Genomic_DNA.
EMBL; AY594256; AAT97595.1; -; Genomic_DNA.
EMBL; AY601634; AAW33410.1; -; Genomic_DNA.
EMBL; GQ478341; ACX32416.1; -; Genomic_DNA.
EMBL; JF800905; AFI24595.1; -; Genomic_DNA.
EMBL; JX625134; AFV96300.1; -; Genomic_DNA.
EMBL; KC440171; AGZ15343.1; -; Genomic_DNA.
EMBL; KC857700; AHJ81838.1; -; Genomic_DNA.
EMBL; KJ019879; AIY53304.1; -; Genomic_DNA.
EMBL; KJ019880; AIY53344.1; -; Genomic_DNA.
EMBL; KJ019881; AIY53384.1; -; Genomic_DNA.
EMBL; KJ019882; AIY53424.1; -; Genomic_DNA.
EMBL; KJ019883; AIY53464.1; -; Genomic_DNA.
EMBL; KJ019884; AIY53504.1; -; Genomic_DNA.
EMBL; KJ019885; AIY53544.1; -; Genomic_DNA.
EMBL; KJ019886; AIY53584.1; -; Genomic_DNA.
EMBL; KJ019887; AIY53624.1; -; Genomic_DNA.
EMBL; KJ019888; AIY53664.1; -; Genomic_DNA.
EMBL; KP670855; AKQ24934.1; -; Genomic_DNA.
EMBL; KP670856; AKQ24973.1; -; Genomic_DNA.
EMBL; KP670857; AKQ25012.1; -; Genomic_DNA.
EMBL; KP670858; AKQ25051.1; -; Genomic_DNA.
EMBL; KP670859; AKQ25090.1; -; Genomic_DNA.
EMBL; KP670860; AKQ25129.1; -; Genomic_DNA.
EMBL; KP670861; AKQ25168.1; -; Genomic_DNA.
EMBL; KT963081; ANI70159.1; -; Genomic_DNA.
EMBL; KX897164; ASK85786.1; -; Genomic_DNA.
EMBL; Z48953; CAA88805.1; -; Genomic_DNA.
PIR; S52811; S52811.
RefSeq; AP_000557.1; AC_000018.1.
Proteomes; UP000097917; Genome.
Proteomes; UP000098519; Genome.
Proteomes; UP000099968; Genome.
Proteomes; UP000102474; Genome.
Proteomes; UP000107022; Genome.
Proteomes; UP000109842; Genome.
Proteomes; UP000110534; Genome.
Proteomes; UP000119312; Genome.
Proteomes; UP000119758; Genome.
Proteomes; UP000120727; Genome.
Proteomes; UP000120913; Genome.
Proteomes; UP000133920; Genome.
Proteomes; UP000134620; Genome.
Proteomes; UP000135507; Genome.
Proteomes; UP000138206; Genome.
Proteomes; UP000143275; Genome.
Proteomes; UP000145850; Genome.
Proteomes; UP000151122; Genome.
Proteomes; UP000155327; Genome.
Proteomes; UP000155520; Genome.
Proteomes; UP000157730; Genome.
Proteomes; UP000160399; Genome.
Proteomes; UP000169742; Genome.
Proteomes; UP000172553; Genome.
Proteomes; UP000173062; Genome.
Proteomes; UP000173900; Genome.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005537; F:mannose binding; IEA:InterPro.
GO; GO:0050690; P:regulation of defense response to virus by virus; IEA:InterPro.
Gene3D; 2.60.40.3530; -; 1.
InterPro; IPR006965; Adenovirus_Gp19K.
InterPro; IPR038710; Adenovirus_Gp19K_sf.
Pfam; PF04881; Adeno_GP19K; 1.
ProDom; PD006739; Adeno_GP19K; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000120727};
Membrane {ECO:0000256|SAM:Phobius};
Reference proteome {ECO:0000313|Proteomes:UP000120727};
Transmembrane {ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAM:Phobius}.
TRANSMEM 131 159 Helical. {ECO:0000256|SAM:Phobius}.
SEQUENCE 172 AA; 19239 MW; 522FFA1665C6BAAF CRC64;
MGAILVVLAL LSLLGLGSAN LNPLDHDPCL DFDPENCTLT FAPDTSRLCG VLIKCGWDCR
SVEITHNNKT WNNTLSTTWE PGVPEWYTVS VRGPDGSIRI SNNTFIFSEM CDLAMFMSRQ
YDLWPPSKEN IVAFSIAYCL VTCIITAIIC VCIHLLIVIR PRQSNKEKEK MP


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