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3-oxoacyl-CoA thiolase (Fragment)

 Q8NCW8_HUMAN            Unreviewed;       326 AA.
Q8NCW8;
01-OCT-2002, integrated into UniProtKB/TrEMBL.
01-OCT-2002, sequence version 1.
30-AUG-2017, entry version 75.
SubName: Full=3-oxoacyl-CoA thiolase {ECO:0000313|EMBL:CAA35825.1};
Flags: Fragment;
Homo sapiens (Human).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
NCBI_TaxID=9606 {ECO:0000313|EMBL:CAA35825.1};
[1] {ECO:0000313|EMBL:CAA35825.1}
NUCLEOTIDE SEQUENCE.
TISSUE=Liver {ECO:0000313|EMBL:CAA35825.1};
Tenchini M.L.;
Submitted (JAN-1990) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|EMBL:CAA35825.1}
NUCLEOTIDE SEQUENCE.
TISSUE=Liver {ECO:0000313|EMBL:CAA35825.1};
Zanelli T., Marchetti L., Princivalle A., Malcovati M., Tenchini M.;
"Adult and foetal human peroxisomal 3-oxoacyl-CoA thiolase are
identical.";
Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases.
-!- SIMILARITY: Belongs to the thiolase family.
{ECO:0000256|RuleBase:RU003557}.
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EMBL; X51460; CAA35825.1; -; mRNA.
UniGene; Hs.643487; -.
ProteinModelPortal; Q8NCW8; -.
PaxDb; Q8NCW8; -.
PeptideAtlas; Q8NCW8; -.
PRIDE; Q8NCW8; -.
eggNOG; KOG1389; Eukaryota.
eggNOG; COG0183; LUCA.
HOVERGEN; HBG003112; -.
GO; GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.
GO; GO:0008152; P:metabolic process; IEA:InterPro.
CDD; cd00751; thiolase; 1.
Gene3D; 3.40.47.10; -; 2.
InterPro; IPR002155; Thiolase.
InterPro; IPR016039; Thiolase-like.
InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
InterPro; IPR020610; Thiolase_AS.
InterPro; IPR020617; Thiolase_C.
InterPro; IPR020613; Thiolase_CS.
InterPro; IPR020616; Thiolase_N.
Pfam; PF02803; Thiolase_C; 1.
Pfam; PF00108; Thiolase_N; 1.
SUPFAM; SSF53901; SSF53901; 2.
TIGRFAMs; TIGR01930; AcCoA-C-Actrans; 1.
PROSITE; PS00098; THIOLASE_1; 1.
PROSITE; PS00737; THIOLASE_2; 1.
PROSITE; PS00099; THIOLASE_3; 1.
2: Evidence at transcript level;
Acyltransferase {ECO:0000256|RuleBase:RU003557};
Transferase {ECO:0000256|RuleBase:RU003557}.
DOMAIN 2 193 Thiolase_N. {ECO:0000259|Pfam:PF00108}.
DOMAIN 202 322 Thiolase_C. {ECO:0000259|Pfam:PF02803}.
NON_TER 1 1 {ECO:0000313|EMBL:CAA35825.1}.
SEQUENCE 326 AA; 34196 MW; 84A000EEA360F3A6 CRC64;
IMARIAQFLS DIPETVPLST VNRQCSSGLQ AVASIAGGIR NGSYDIGMAC GVESMSLADR
GNPGNITSRL MEKEKARDCL IPMGITSENV AERFGISREK QDTFALASQQ KAARAQSKGC
FQAEIVPVTT TVHDDKGTKR SITVTQDEGI RPSTTMEGLA KLKPAFKKDG STTAGNSSQV
SDGAAAILLA RRSKAEELGL PILGVLRSYA VVGVPPDIMG IGPAYAIPVA LQKAGLTVSD
VDIFEINEAF ASQAAYCVEK LRLPPEKVNP LGGAVALGHP LGCTGARQVI TLLNELKRRG
KRAYGVVSMC IGTGMGAAAV FEYPGN


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