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5-hydroxytryptamine receptor 2A (5-HT receptor 2A) (Serotonin receptor 2A)

 5HT2A_DROME             Reviewed;         834 AA.
P28285; Q0E921; Q4QQC9; Q5MTE9; Q5MTF1; Q5MTF2; Q5MTF3; Q5MTF8;
Q5MTF9; Q5MTG0; Q5MTG1; Q5MTG2; Q5MTG3; Q5MTG4; Q5MTG6; Q5MTG9;
Q5MTH1; Q5MTH2; Q5MTH5; Q5MTH6; Q5MTH7; Q5MTH9; Q5MTI0; Q5MTI1;
Q5MTI4; Q5MTI6; Q5MTI7; Q5MTI8; Q5MTJ0; Q5MTJ4; Q5MTJ5; Q5MTJ6;
Q5MTJ9; Q5MTK5; Q5MTL1; Q5MTL5; Q5MTL6; Q5MTM2; Q5MTM5; Q5MTM8;
Q5MTN6; Q5MTQ1; Q5MTQ4; Q5MTR1; Q5MTR3; Q5MTR6; Q5MTR8; Q5MTS1;
Q5MTT8; Q5MTV6; Q5MTV7; Q5MTV9; Q5MTW8; Q5MTX2; Q5MTX7; Q5MTY3;
Q5MTY7; Q5MTY8; Q5MTY9; Q5MTZ0; Q5MTZ6; Q5MUJ0; Q5MUK2; Q5MUK5;
Q5MUK8; Q5MUL0; Q5MUL2; Q5MUL5; Q5MUM3; Q5MUM7; Q5MUM9; Q5MUN0;
Q5MUN1; Q5MUN2; Q5MUP0; Q5MUP5; Q5MUP6; Q5MUP7; Q5MUP8; Q5MUQ1;
Q5MUQ6; Q5MUQ7; Q5MUQ8; Q5MUQ9; Q5MUR1; Q5MUR2; Q5MUR3; Q5MUR4;
Q5MUR5; Q5MUT3; Q5MUT4; Q5MUT7; Q5MUT9; Q5MUU2; Q5MUU5; Q5MUU6;
Q5MUV4; Q5MUV5; Q5MUV8; Q5MUV9; Q5MUW3; Q5MUW4; Q5MUW7; Q5MUX4;
Q5MUX6; Q5MUY1; Q5MUY3; Q5MV05; Q5MV06; Q5MV07; Q5MV08; Q5MV13;
Q5MV14; Q5MV15; Q5MV26; Q5MV30; Q9V8Q9;
01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
12-APR-2005, sequence version 2.
22-NOV-2017, entry version 130.
RecName: Full=5-hydroxytryptamine receptor 2A;
Short=5-HT receptor 2A;
AltName: Full=Serotonin receptor 2A;
Name=5-HT1A; Synonyms=5HT-R2A; ORFNames=CG16720;
Drosophila melanogaster (Fruit fly).
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
Ephydroidea; Drosophilidae; Drosophila; Sophophora.
NCBI_TaxID=7227;
[1]
NUCLEOTIDE SEQUENCE [MRNA], AND VARIANTS ALA-96 AND ASN-196.
STRAIN=Canton-S, and Oregon-R; TISSUE=Head;
PubMed=1310937;
Saudou F., Boschert U., Amlaiky N., Plassat J.-L., Hen R.;
"A family of Drosophila serotonin receptors with distinct
intracellular signalling properties and expression patterns.";
EMBO J. 11:7-17(1992).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND VARIANT MET-588.
STRAIN=Berkeley;
PubMed=10731132; DOI=10.1126/science.287.5461.2185;
Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X.,
Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D.,
Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G.,
Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D.,
Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M.,
Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S.,
Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P.,
Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I.,
Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P.,
de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M.,
Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P.,
Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W.,
Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K.,
Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J.,
Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C.,
Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A.,
Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z.,
Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X.,
Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D.,
Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A.,
Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L.,
Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M.,
Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G.,
Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H.,
Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
Spier E., Spradling A.C., Stapleton M., Strong R., Sun E.,
Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X.,
Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J.,
Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A.,
Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L.,
Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X.,
Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.;
"The genome sequence of Drosophila melanogaster.";
Science 287:2185-2195(2000).
[3]
GENOME REANNOTATION.
STRAIN=Berkeley;
PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q.,
Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M.,
Lewis S.E.;
"Annotation of the Drosophila melanogaster euchromatic genome: a
systematic review.";
Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANT MET-588.
STRAIN=Berkeley; TISSUE=Embryo;
Stapleton M., Carlson J.W., Chavez C., Frise E., George R.A.,
Pacleb J.M., Park S., Wan K.H., Yu C., Celniker S.E.;
Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
[5]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-242, NUCLEOTIDE SEQUENCE
[GENOMIC DNA] OF 511-834, AND VARIANTS 29-GLU--PRO-32 DEL; GLN-46;
VAL-49; GLU-51; GLU-52; GLY-54; THR-76; THR-86; GLN-91; ALA-96;
THR-143; THR-146; VAL-171; ASP-182; TYR-184; ASN-196; HIS-198;
GLY-213; LEU-531; ALA-536; 547-ALA--GLY-550 DELINS
GLY-PRO-MET-GLY-PRO-LEU; VAL-571; LYS-585; MET-588; ARG-589; VAL-648;
PRO-657; TRP-682; ILE-688; THR-692; THR-706; HIS-716; GLN-HIS-716 INS;
716-GLN-GLN-717 DEL; 716-GLN--GLN-718 DEL AND 717-GLN--GLN-719 DELINS
HIS.
STRAIN=CA-001, CA-002, CA-003, CA-008, CA-009, CA-010, CA-011, CA-012,
CA-013, CA-015, CA-017, CA-018, CA-023, CA-026, CA-027, CA-030,
CA-031, CA-033, CA-034, CA-035, CA-037, CA-040, CA-041, CA-043,
CA-044, CA-045, CA-046, CA-047, CA-048, CA-052, CA-055, CA-056,
CA-057, CA-058, CA-060, CA-061, CA-062, CA-063, CA-064, CA-065,
CA-066, CA-068, CA-069, CA-070, CA-072, CA-073, CA-075, CA-081,
CA-083, CA-086, CA-087, CA-088, CA-089, CA-090, CA-091, CA-093,
CA-095, CA-096, CA-100, CA-105, CA-113, CA-114, CA-115, CA-118,
CA-120, CA-123, CA-126, CA-127, CA-128, CA-129, CA-130, CA-132,
CA-133, CA-136, CA-137, CA-140, CA-142, CA-144, CA-145, CA-147,
CA-148, NC-001, NC-002, NC-003, NC-004, NC-005, NC-006, NC-008,
NC-010, NC-011, NC-012, NC-013, NC-014, NC-015, NC-017, NC-021,
NC-022, NC-023, NC-024, NC-025, NC-026, NC-027, NC-028, NC-029,
NC-030, NC-032, NC-033, NC-034, NC-036, NC-037, NC-038, NC-039,
NC-040, NC-041, NC-042, NC-043, NC-044, NC-046, NC-047, NC-048,
NC-049, NC-050, NC-051, NC-052, NC-053, NC-054, NC-057, NC-058,
NC-059, NC-060, NC-061, NC-064, NC-066, NC-067, NC-068, NC-069,
NC-070, NC-071, NC-072, NC-073, NC-074, NC-075, NC-077, NC-079,
NC-080, NC-081, NC-084, NC-086, NC-087, NC-088, NC-089, NC-091,
NC-092, NC-094, NC-095, NC-096, NC-097, NC-098, NC-100, NC-101,
NC-103, NC-104, NC-105, NC-107, NC-108, NC-109, NC-110, NC-111,
NC-112, NC-113, NC-114, NC-115, NC-116, NC-118, NC-119, NC-121,
NC-123, NC-124, NC-125, NC-126, NC-127, NC-128, NC-129, NC-131,
NC-133, NC-134, NC-135, NC-136, NC-137, NC-138, NC-139, NC-141,
NC-142, NC-144, NC-146, NC-147, NC-148, NC-149, and NC-150;
PubMed=15611167; DOI=10.1534/genetics.104.028712;
Nikoh N., Duty A., Gibson G.;
"Effects of population structure and sex on association between
serotonin receptors and Drosophila heart rate.";
Genetics 168:1963-1974(2004).
-!- FUNCTION: This is one of the several different receptors for 5-
hydroxytryptamine (serotonin), a biogenic hormone that functions
as a neurotransmitter, a hormone, and a mitogen. The activity of
this receptor is mediated by G proteins which inhibit adenylate
cyclase.
-!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
-!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
{ECO:0000255|PROSITE-ProRule:PRU00521}.
-!- SEQUENCE CAUTION:
Sequence=AAY84887.1; Type=Erroneous termination; Positions=49; Note=Translated as Glu.; Evidence={ECO:0000305};
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EMBL; Z11489; CAA77570.1; -; mRNA.
EMBL; AE013599; AAF57603.1; -; Genomic_DNA.
EMBL; AE013599; AAM68432.1; -; Genomic_DNA.
EMBL; BT023487; AAY84887.1; ALT_SEQ; mRNA.
EMBL; AY564785; AAS73796.1; -; Genomic_DNA.
EMBL; AY564786; AAS73797.1; -; Genomic_DNA.
EMBL; AY564787; AAS73798.1; -; Genomic_DNA.
EMBL; AY564788; AAS73799.1; -; Genomic_DNA.
EMBL; AY564789; AAS73800.1; -; Genomic_DNA.
EMBL; AY564790; AAS73801.1; -; Genomic_DNA.
EMBL; AY564791; AAS73802.1; -; Genomic_DNA.
EMBL; AY564792; AAS73803.1; -; Genomic_DNA.
EMBL; AY564793; AAS73804.1; -; Genomic_DNA.
EMBL; AY564794; AAS73805.1; -; Genomic_DNA.
EMBL; AY564795; AAS73806.1; -; Genomic_DNA.
EMBL; AY564796; AAS73807.1; -; Genomic_DNA.
EMBL; AY564797; AAS73808.1; -; Genomic_DNA.
EMBL; AY564798; AAS73809.1; -; Genomic_DNA.
EMBL; AY564799; AAS73810.1; -; Genomic_DNA.
EMBL; AY564800; AAS73811.1; -; Genomic_DNA.
EMBL; AY564801; AAS73812.1; -; Genomic_DNA.
EMBL; AY564802; AAS73813.1; -; Genomic_DNA.
EMBL; AY564803; AAS73814.1; -; Genomic_DNA.
EMBL; AY564804; AAS73815.1; -; Genomic_DNA.
EMBL; AY564805; AAS73816.1; -; Genomic_DNA.
EMBL; AY564806; AAS73817.1; -; Genomic_DNA.
EMBL; AY564807; AAS73818.1; -; Genomic_DNA.
EMBL; AY564808; AAS73819.1; -; Genomic_DNA.
EMBL; AY564809; AAS73820.1; -; Genomic_DNA.
EMBL; AY564810; AAS73821.1; -; Genomic_DNA.
EMBL; AY564811; AAS73822.1; -; Genomic_DNA.
EMBL; AY564812; AAS73823.1; -; Genomic_DNA.
EMBL; AY564813; AAS73824.1; -; Genomic_DNA.
EMBL; AY564814; AAS73825.1; -; Genomic_DNA.
EMBL; AY564815; AAS73826.1; -; Genomic_DNA.
EMBL; AY564816; AAS73827.1; -; Genomic_DNA.
EMBL; AY564817; AAS73828.1; -; Genomic_DNA.
EMBL; AY564818; AAS73829.1; -; Genomic_DNA.
EMBL; AY564819; AAS73830.1; -; Genomic_DNA.
EMBL; AY564820; AAS73831.1; -; Genomic_DNA.
EMBL; AY564821; AAS73832.1; -; Genomic_DNA.
EMBL; AY564822; AAS73833.1; -; Genomic_DNA.
EMBL; AY564823; AAS73834.1; -; Genomic_DNA.
EMBL; AY564824; AAS73835.1; -; Genomic_DNA.
EMBL; AY564825; AAS73836.1; -; Genomic_DNA.
EMBL; AY564826; AAS73837.1; -; Genomic_DNA.
EMBL; AY564827; AAS73838.1; -; Genomic_DNA.
EMBL; AY564828; AAS73839.1; -; Genomic_DNA.
EMBL; AY564829; AAS73840.1; -; Genomic_DNA.
EMBL; AY564830; AAS73841.1; -; Genomic_DNA.
EMBL; AY564831; AAS73842.1; -; Genomic_DNA.
EMBL; AY564832; AAS73843.1; -; Genomic_DNA.
EMBL; AY564833; AAS73844.1; -; Genomic_DNA.
EMBL; AY564834; AAS73845.1; -; Genomic_DNA.
EMBL; AY564835; AAS73846.1; -; Genomic_DNA.
EMBL; AY564836; AAS73847.1; -; Genomic_DNA.
EMBL; AY564837; AAS73848.1; -; Genomic_DNA.
EMBL; AY564838; AAS73849.1; -; Genomic_DNA.
EMBL; AY564839; AAS73850.1; -; Genomic_DNA.
EMBL; AY564840; AAS73851.1; -; Genomic_DNA.
EMBL; AY564841; AAS73852.1; -; Genomic_DNA.
EMBL; AY564842; AAS73853.1; -; Genomic_DNA.
EMBL; AY564843; AAS73854.1; -; Genomic_DNA.
EMBL; AY564844; AAS73855.1; -; Genomic_DNA.
EMBL; AY564845; AAS73856.1; -; Genomic_DNA.
EMBL; AY564846; AAS73857.1; -; Genomic_DNA.
EMBL; AY564847; AAS73858.1; -; Genomic_DNA.
EMBL; AY564848; AAS73859.1; -; Genomic_DNA.
EMBL; AY564849; AAS73860.1; -; Genomic_DNA.
EMBL; AY564850; AAS73861.1; -; Genomic_DNA.
EMBL; AY564851; AAS73862.1; -; Genomic_DNA.
EMBL; AY564852; AAS73863.1; -; Genomic_DNA.
EMBL; AY564853; AAS73864.1; -; Genomic_DNA.
EMBL; AY564854; AAS73865.1; -; Genomic_DNA.
EMBL; AY564855; AAS73866.1; -; Genomic_DNA.
EMBL; AY564856; AAS73867.1; -; Genomic_DNA.
EMBL; AY564857; AAS73868.1; -; Genomic_DNA.
EMBL; AY564858; AAS73869.1; -; Genomic_DNA.
EMBL; AY564859; AAS73870.1; -; Genomic_DNA.
EMBL; AY564860; AAS73871.1; -; Genomic_DNA.
EMBL; AY564861; AAS73872.1; -; Genomic_DNA.
EMBL; AY564862; AAS73873.1; -; Genomic_DNA.
EMBL; AY564863; AAS73874.1; -; Genomic_DNA.
EMBL; AY564864; AAS73875.1; -; Genomic_DNA.
EMBL; AY564865; AAS73876.1; -; Genomic_DNA.
EMBL; AY564866; AAS73877.1; -; Genomic_DNA.
EMBL; AY564867; AAS73878.1; -; Genomic_DNA.
EMBL; AY564868; AAS73879.1; -; Genomic_DNA.
EMBL; AY564869; AAS73880.1; -; Genomic_DNA.
EMBL; AY564870; AAS73881.1; -; Genomic_DNA.
EMBL; AY564871; AAS73882.1; -; Genomic_DNA.
EMBL; AY564872; AAS73883.1; -; Genomic_DNA.
EMBL; AY564873; AAS73884.1; -; Genomic_DNA.
EMBL; AY564874; AAS73885.1; -; Genomic_DNA.
EMBL; AY564875; AAS73886.1; -; Genomic_DNA.
EMBL; AY564876; AAS73887.1; -; Genomic_DNA.
EMBL; AY564877; AAS73888.1; -; Genomic_DNA.
EMBL; AY564878; AAS73889.1; -; Genomic_DNA.
EMBL; AY564879; AAS73890.1; -; Genomic_DNA.
EMBL; AY564880; AAS73891.1; -; Genomic_DNA.
EMBL; AY564881; AAS73892.1; -; Genomic_DNA.
EMBL; AY564882; AAS73893.1; -; Genomic_DNA.
EMBL; AY564883; AAS73894.1; -; Genomic_DNA.
EMBL; AY564884; AAS73895.1; -; Genomic_DNA.
EMBL; AY564885; AAS73896.1; -; Genomic_DNA.
EMBL; AY564886; AAS73897.1; -; Genomic_DNA.
EMBL; AY564887; AAS73898.1; -; Genomic_DNA.
EMBL; AY564888; AAS73899.1; -; Genomic_DNA.
EMBL; AY564889; AAS73900.1; -; Genomic_DNA.
EMBL; AY564890; AAS73901.1; -; Genomic_DNA.
EMBL; AY564891; AAS73902.1; -; Genomic_DNA.
EMBL; AY564892; AAS73903.1; -; Genomic_DNA.
EMBL; AY564893; AAS73904.1; -; Genomic_DNA.
EMBL; AY564894; AAS73905.1; -; Genomic_DNA.
EMBL; AY564895; AAS73906.1; -; Genomic_DNA.
EMBL; AY564896; AAS73907.1; -; Genomic_DNA.
EMBL; AY564897; AAS73908.1; -; Genomic_DNA.
EMBL; AY564898; AAS73909.1; -; Genomic_DNA.
EMBL; AY564899; AAS73910.1; -; Genomic_DNA.
EMBL; AY564900; AAS73911.1; -; Genomic_DNA.
EMBL; AY564901; AAS73912.1; -; Genomic_DNA.
EMBL; AY564902; AAS73913.1; -; Genomic_DNA.
EMBL; AY564903; AAS73914.1; -; Genomic_DNA.
EMBL; AY564904; AAS73915.1; -; Genomic_DNA.
EMBL; AY564905; AAS73916.1; -; Genomic_DNA.
EMBL; AY564906; AAS73917.1; -; Genomic_DNA.
EMBL; AY564907; AAS73918.1; -; Genomic_DNA.
EMBL; AY564908; AAS73919.1; -; Genomic_DNA.
EMBL; AY564909; AAS73920.1; -; Genomic_DNA.
EMBL; AY564910; AAS73921.1; -; Genomic_DNA.
EMBL; AY564911; AAS73922.1; -; Genomic_DNA.
EMBL; AY564912; AAS73923.1; -; Genomic_DNA.
EMBL; AY564913; AAS73924.1; -; Genomic_DNA.
EMBL; AY564914; AAS73925.1; -; Genomic_DNA.
EMBL; AY564915; AAS73926.1; -; Genomic_DNA.
EMBL; AY564916; AAS73927.1; -; Genomic_DNA.
EMBL; AY564917; AAS73928.1; -; Genomic_DNA.
EMBL; AY564918; AAS73929.1; -; Genomic_DNA.
EMBL; AY564919; AAS73930.1; -; Genomic_DNA.
EMBL; AY564920; AAS73931.1; -; Genomic_DNA.
EMBL; AY564921; AAS73932.1; -; Genomic_DNA.
EMBL; AY564922; AAS73933.1; -; Genomic_DNA.
EMBL; AY564925; AAS73936.1; -; Genomic_DNA.
EMBL; AY564926; AAS73937.1; -; Genomic_DNA.
EMBL; AY564927; AAS73938.1; -; Genomic_DNA.
EMBL; AY564928; AAS73939.1; -; Genomic_DNA.
EMBL; AY564929; AAS73940.1; -; Genomic_DNA.
EMBL; AY564930; AAS73941.1; -; Genomic_DNA.
EMBL; AY564931; AAS73942.1; -; Genomic_DNA.
EMBL; AY564932; AAS73943.1; -; Genomic_DNA.
EMBL; AY564933; AAS73944.1; -; Genomic_DNA.
EMBL; AY564934; AAS73945.1; -; Genomic_DNA.
EMBL; AY564935; AAS73946.1; -; Genomic_DNA.
EMBL; AY564936; AAS73947.1; -; Genomic_DNA.
EMBL; AY564937; AAS73948.1; -; Genomic_DNA.
EMBL; AY564938; AAS73949.1; -; Genomic_DNA.
EMBL; AY564939; AAS73950.1; -; Genomic_DNA.
EMBL; AY564940; AAS73951.1; -; Genomic_DNA.
EMBL; AY564941; AAS73952.1; -; Genomic_DNA.
EMBL; AY564942; AAS73953.1; -; Genomic_DNA.
EMBL; AY564943; AAS73954.1; -; Genomic_DNA.
EMBL; AY564944; AAS73955.1; -; Genomic_DNA.
EMBL; AY564945; AAS73956.1; -; Genomic_DNA.
EMBL; AY564946; AAS73957.1; -; Genomic_DNA.
EMBL; AY564947; AAS73958.1; -; Genomic_DNA.
EMBL; AY564948; AAS73959.1; -; Genomic_DNA.
EMBL; AY564949; AAS73960.1; -; Genomic_DNA.
EMBL; AY564950; AAS73961.1; -; Genomic_DNA.
EMBL; AY564951; AAS73962.1; -; Genomic_DNA.
EMBL; AY564952; AAS73963.1; -; Genomic_DNA.
EMBL; AY564953; AAS73964.1; -; Genomic_DNA.
EMBL; AY564954; AAS73965.1; -; Genomic_DNA.
EMBL; AY564955; AAS73966.1; -; Genomic_DNA.
EMBL; AY564956; AAS73967.1; -; Genomic_DNA.
EMBL; AY564958; AAS73968.1; -; Genomic_DNA.
EMBL; AY564959; AAS73969.1; -; Genomic_DNA.
EMBL; AY564960; AAS73970.1; -; Genomic_DNA.
EMBL; AY564961; AAS73971.1; -; Genomic_DNA.
EMBL; AY564962; AAS73972.1; -; Genomic_DNA.
EMBL; AY564963; AAS73973.1; -; Genomic_DNA.
EMBL; AY564964; AAS73974.1; -; Genomic_DNA.
EMBL; AY564965; AAS73975.1; -; Genomic_DNA.
EMBL; AY564966; AAS73976.1; -; Genomic_DNA.
EMBL; AY564967; AAS73977.1; -; Genomic_DNA.
EMBL; AY564968; AAS73978.1; -; Genomic_DNA.
EMBL; AY564969; AAS73979.1; -; Genomic_DNA.
EMBL; AY564971; AAS73981.1; -; Genomic_DNA.
EMBL; AY564972; AAS73982.1; -; Genomic_DNA.
EMBL; AY564973; AAS73983.1; -; Genomic_DNA.
EMBL; AY564974; AAS73984.1; -; Genomic_DNA.
EMBL; AY564975; AAS73985.1; -; Genomic_DNA.
EMBL; AY564976; AAS73986.1; -; Genomic_DNA.
EMBL; AY564977; AAS73987.1; -; Genomic_DNA.
EMBL; AY565171; AAS74181.1; -; Genomic_DNA.
EMBL; AY565172; AAS74182.1; -; Genomic_DNA.
EMBL; AY565173; AAS74183.1; -; Genomic_DNA.
EMBL; AY565174; AAS74184.1; -; Genomic_DNA.
EMBL; AY565175; AAS74185.1; -; Genomic_DNA.
EMBL; AY565176; AAS74186.1; -; Genomic_DNA.
EMBL; AY565177; AAS74187.1; -; Genomic_DNA.
EMBL; AY565178; AAS74188.1; -; Genomic_DNA.
EMBL; AY565179; AAS74189.1; -; Genomic_DNA.
EMBL; AY565180; AAS74190.1; -; Genomic_DNA.
EMBL; AY565181; AAS74191.1; -; Genomic_DNA.
EMBL; AY565182; AAS74192.1; -; Genomic_DNA.
EMBL; AY565183; AAS74193.1; -; Genomic_DNA.
EMBL; AY565184; AAS74194.1; -; Genomic_DNA.
EMBL; AY565185; AAS74195.1; -; Genomic_DNA.
EMBL; AY565186; AAS74196.1; -; Genomic_DNA.
EMBL; AY565187; AAS74197.1; -; Genomic_DNA.
EMBL; AY565188; AAS74198.1; -; Genomic_DNA.
EMBL; AY565189; AAS74199.1; -; Genomic_DNA.
EMBL; AY565190; AAS74200.1; -; Genomic_DNA.
EMBL; AY565191; AAS74201.1; -; Genomic_DNA.
EMBL; AY565192; AAS74202.1; -; Genomic_DNA.
EMBL; AY565193; AAS74203.1; -; Genomic_DNA.
EMBL; AY565194; AAS74204.1; -; Genomic_DNA.
EMBL; AY565195; AAS74205.1; -; Genomic_DNA.
EMBL; AY565196; AAS74206.1; -; Genomic_DNA.
EMBL; AY565197; AAS74207.1; -; Genomic_DNA.
EMBL; AY565198; AAS74208.1; -; Genomic_DNA.
EMBL; AY565199; AAS74209.1; -; Genomic_DNA.
EMBL; AY565200; AAS74210.1; -; Genomic_DNA.
EMBL; AY565201; AAS74211.1; -; Genomic_DNA.
EMBL; AY565202; AAS74212.1; -; Genomic_DNA.
EMBL; AY565203; AAS74213.1; -; Genomic_DNA.
EMBL; AY565204; AAS74214.1; -; Genomic_DNA.
EMBL; AY565205; AAS74215.1; -; Genomic_DNA.
EMBL; AY565206; AAS74216.1; -; Genomic_DNA.
EMBL; AY565207; AAS74217.1; -; Genomic_DNA.
EMBL; AY565208; AAS74218.1; -; Genomic_DNA.
EMBL; AY565209; AAS74219.1; -; Genomic_DNA.
EMBL; AY565210; AAS74220.1; -; Genomic_DNA.
EMBL; AY565211; AAS74221.1; -; Genomic_DNA.
EMBL; AY565212; AAS74222.1; -; Genomic_DNA.
EMBL; AY565213; AAS74223.1; -; Genomic_DNA.
EMBL; AY565214; AAS74224.1; -; Genomic_DNA.
EMBL; AY565215; AAS74225.1; -; Genomic_DNA.
EMBL; AY565216; AAS74226.1; -; Genomic_DNA.
EMBL; AY565217; AAS74227.1; -; Genomic_DNA.
EMBL; AY565218; AAS74228.1; -; Genomic_DNA.
EMBL; AY565219; AAS74229.1; -; Genomic_DNA.
EMBL; AY565220; AAS74230.1; -; Genomic_DNA.
EMBL; AY565221; AAS74231.1; -; Genomic_DNA.
EMBL; AY565222; AAS74232.1; -; Genomic_DNA.
EMBL; AY565223; AAS74233.1; -; Genomic_DNA.
EMBL; AY565224; AAS74234.1; -; Genomic_DNA.
EMBL; AY565225; AAS74235.1; -; Genomic_DNA.
EMBL; AY565226; AAS74236.1; -; Genomic_DNA.
EMBL; AY565227; AAS74237.1; -; Genomic_DNA.
EMBL; AY565228; AAS74238.1; -; Genomic_DNA.
EMBL; AY565229; AAS74239.1; -; Genomic_DNA.
EMBL; AY565230; AAS74240.1; -; Genomic_DNA.
EMBL; AY565231; AAS74241.1; -; Genomic_DNA.
EMBL; AY565232; AAS74242.1; -; Genomic_DNA.
EMBL; AY565233; AAS74243.1; -; Genomic_DNA.
EMBL; AY565234; AAS74244.1; -; Genomic_DNA.
EMBL; AY565235; AAS74245.1; -; Genomic_DNA.
EMBL; AY565236; AAS74246.1; -; Genomic_DNA.
EMBL; AY565237; AAS74247.1; -; Genomic_DNA.
EMBL; AY565238; AAS74248.1; -; Genomic_DNA.
EMBL; AY565239; AAS74249.1; -; Genomic_DNA.
EMBL; AY565240; AAS74250.1; -; Genomic_DNA.
EMBL; AY565241; AAS74251.1; -; Genomic_DNA.
EMBL; AY565242; AAS74252.1; -; Genomic_DNA.
EMBL; AY565243; AAS74253.1; -; Genomic_DNA.
EMBL; AY565244; AAS74254.1; -; Genomic_DNA.
EMBL; AY565245; AAS74255.1; -; Genomic_DNA.
EMBL; AY565246; AAS74256.1; -; Genomic_DNA.
EMBL; AY565247; AAS74257.1; -; Genomic_DNA.
EMBL; AY565248; AAS74258.1; -; Genomic_DNA.
EMBL; AY565249; AAS74259.1; -; Genomic_DNA.
EMBL; AY565250; AAS74260.1; -; Genomic_DNA.
EMBL; AY565251; AAS74261.1; -; Genomic_DNA.
EMBL; AY565252; AAS74262.1; -; Genomic_DNA.
EMBL; AY565253; AAS74263.1; -; Genomic_DNA.
EMBL; AY565254; AAS74264.1; -; Genomic_DNA.
EMBL; AY565255; AAS74265.1; -; Genomic_DNA.
EMBL; AY565256; AAS74266.1; -; Genomic_DNA.
EMBL; AY565257; AAS74267.1; -; Genomic_DNA.
EMBL; AY565258; AAS74268.1; -; Genomic_DNA.
EMBL; AY565259; AAS74269.1; -; Genomic_DNA.
EMBL; AY565260; AAS74270.1; -; Genomic_DNA.
EMBL; AY565261; AAS74271.1; -; Genomic_DNA.
EMBL; AY565262; AAS74272.1; -; Genomic_DNA.
EMBL; AY565263; AAS74273.1; -; Genomic_DNA.
EMBL; AY565264; AAS74274.1; -; Genomic_DNA.
EMBL; AY565265; AAS74275.1; -; Genomic_DNA.
EMBL; AY565266; AAS74276.1; -; Genomic_DNA.
EMBL; AY565267; AAS74277.1; -; Genomic_DNA.
EMBL; AY565268; AAS74278.1; -; Genomic_DNA.
EMBL; AY565269; AAS74279.1; -; Genomic_DNA.
EMBL; AY565270; AAS74280.1; -; Genomic_DNA.
EMBL; AY565271; AAS74281.1; -; Genomic_DNA.
EMBL; AY565272; AAS74282.1; -; Genomic_DNA.
EMBL; AY565273; AAS74283.1; -; Genomic_DNA.
EMBL; AY565274; AAS74284.1; -; Genomic_DNA.
EMBL; AY565275; AAS74285.1; -; Genomic_DNA.
EMBL; AY565276; AAS74286.1; -; Genomic_DNA.
EMBL; AY565277; AAS74287.1; -; Genomic_DNA.
EMBL; AY565278; AAS74288.1; -; Genomic_DNA.
EMBL; AY565279; AAS74289.1; -; Genomic_DNA.
EMBL; AY565280; AAS74290.1; -; Genomic_DNA.
EMBL; AY565281; AAS74291.1; -; Genomic_DNA.
EMBL; AY565282; AAS74292.1; -; Genomic_DNA.
EMBL; AY565283; AAS74293.1; -; Genomic_DNA.
EMBL; AY565284; AAS74294.1; -; Genomic_DNA.
EMBL; AY565285; AAS74295.1; -; Genomic_DNA.
EMBL; AY565286; AAS74296.1; -; Genomic_DNA.
EMBL; AY565287; AAS74297.1; -; Genomic_DNA.
EMBL; AY565288; AAS74298.1; -; Genomic_DNA.
EMBL; AY565289; AAS74299.1; -; Genomic_DNA.
EMBL; AY565290; AAS74300.1; -; Genomic_DNA.
EMBL; AY565291; AAS74301.1; -; Genomic_DNA.
EMBL; AY565292; AAS74302.1; -; Genomic_DNA.
EMBL; AY565293; AAS74303.1; -; Genomic_DNA.
EMBL; AY565294; AAS74304.1; -; Genomic_DNA.
EMBL; AY565295; AAS74305.1; -; Genomic_DNA.
EMBL; AY565296; AAS74306.1; -; Genomic_DNA.
EMBL; AY565297; AAS74307.1; -; Genomic_DNA.
EMBL; AY565298; AAS74308.1; -; Genomic_DNA.
EMBL; AY565299; AAS74309.1; -; Genomic_DNA.
EMBL; AY565300; AAS74310.1; -; Genomic_DNA.
EMBL; AY565301; AAS74311.1; -; Genomic_DNA.
EMBL; AY565302; AAS74312.1; -; Genomic_DNA.
EMBL; AY565303; AAS74313.1; -; Genomic_DNA.
EMBL; AY565304; AAS74314.1; -; Genomic_DNA.
EMBL; AY565305; AAS74315.1; -; Genomic_DNA.
EMBL; AY565306; AAS74316.1; -; Genomic_DNA.
EMBL; AY565307; AAS74317.1; -; Genomic_DNA.
EMBL; AY565308; AAS74318.1; -; Genomic_DNA.
EMBL; AY565309; AAS74319.1; -; Genomic_DNA.
EMBL; AY565310; AAS74320.1; -; Genomic_DNA.
EMBL; AY565311; AAS74321.1; -; Genomic_DNA.
EMBL; AY565312; AAS74322.1; -; Genomic_DNA.
EMBL; AY565313; AAS74323.1; -; Genomic_DNA.
EMBL; AY565314; AAS74324.1; -; Genomic_DNA.
EMBL; AY565315; AAS74325.1; -; Genomic_DNA.
EMBL; AY565316; AAS74326.1; -; Genomic_DNA.
EMBL; AY565317; AAS74327.1; -; Genomic_DNA.
EMBL; AY565318; AAS74328.1; -; Genomic_DNA.
EMBL; AY565319; AAS74329.1; -; Genomic_DNA.
EMBL; AY565320; AAS74330.1; -; Genomic_DNA.
EMBL; AY565321; AAS74331.1; -; Genomic_DNA.
EMBL; AY565322; AAS74332.1; -; Genomic_DNA.
EMBL; AY565323; AAS74333.1; -; Genomic_DNA.
EMBL; AY565324; AAS74334.1; -; Genomic_DNA.
EMBL; AY565325; AAS74335.1; -; Genomic_DNA.
EMBL; AY565326; AAS74336.1; -; Genomic_DNA.
EMBL; AY565327; AAS74337.1; -; Genomic_DNA.
EMBL; AY565328; AAS74338.1; -; Genomic_DNA.
EMBL; AY565329; AAS74339.1; -; Genomic_DNA.
EMBL; AY565330; AAS74340.1; -; Genomic_DNA.
EMBL; AY565331; AAS74341.1; -; Genomic_DNA.
EMBL; AY565332; AAS74342.1; -; Genomic_DNA.
EMBL; AY565333; AAS74343.1; -; Genomic_DNA.
EMBL; AY565334; AAS74344.1; -; Genomic_DNA.
EMBL; AY565335; AAS74345.1; -; Genomic_DNA.
EMBL; AY565336; AAS74346.1; -; Genomic_DNA.
EMBL; AY565337; AAS74347.1; -; Genomic_DNA.
EMBL; AY565338; AAS74348.1; -; Genomic_DNA.
EMBL; AY565339; AAS74349.1; -; Genomic_DNA.
EMBL; AY565340; AAS74350.1; -; Genomic_DNA.
EMBL; AY565341; AAS74351.1; -; Genomic_DNA.
EMBL; AY565342; AAS74352.1; -; Genomic_DNA.
EMBL; AY565343; AAS74353.1; -; Genomic_DNA.
EMBL; AY565344; AAS74354.1; -; Genomic_DNA.
EMBL; AY565345; AAS74355.1; -; Genomic_DNA.
EMBL; AY565346; AAS74356.1; -; Genomic_DNA.
EMBL; AY565347; AAS74357.1; -; Genomic_DNA.
EMBL; AY565348; AAS74358.1; -; Genomic_DNA.
EMBL; AY565349; AAS74359.1; -; Genomic_DNA.
EMBL; AY565350; AAS74360.1; -; Genomic_DNA.
EMBL; AY565351; AAS74361.1; -; Genomic_DNA.
EMBL; AY565352; AAS74362.1; -; Genomic_DNA.
EMBL; AY565353; AAS74363.1; -; Genomic_DNA.
EMBL; AY565354; AAS74364.1; -; Genomic_DNA.
EMBL; AY565355; AAS74365.1; -; Genomic_DNA.
EMBL; AY565356; AAS74366.1; -; Genomic_DNA.
EMBL; AY565357; AAS74367.1; -; Genomic_DNA.
EMBL; AY565358; AAS74368.1; -; Genomic_DNA.
EMBL; AY565359; AAS74369.1; -; Genomic_DNA.
EMBL; AY565360; AAS74370.1; -; Genomic_DNA.
EMBL; AY565361; AAS74371.1; -; Genomic_DNA.
EMBL; AY565362; AAS74372.1; -; Genomic_DNA.
EMBL; AY565363; AAS74373.1; -; Genomic_DNA.
EMBL; AY565364; AAS74374.1; -; Genomic_DNA.
EMBL; AY565365; AAS74375.1; -; Genomic_DNA.
EMBL; AY565366; AAS74376.1; -; Genomic_DNA.
EMBL; AY565367; AAS74377.1; -; Genomic_DNA.
EMBL; AY565368; AAS74378.1; -; Genomic_DNA.
PIR; S19155; S19155.
RefSeq; NP_725849.1; NM_166322.2.
UniGene; Dm.4703; -.
ProteinModelPortal; P28285; -.
SMR; P28285; -.
STRING; 7227.FBpp0085761; -.
PaxDb; P28285; -.
PRIDE; P28285; -.
GeneID; 37196; -.
KEGG; dme:Dmel_CG16720; -.
CTD; 37196; -.
FlyBase; FBgn0004168; 5-HT1A.
eggNOG; KOG3656; Eukaryota.
eggNOG; ENOG410XRW9; LUCA.
InParanoid; P28285; -.
KO; K04153; -.
OrthoDB; EOG091G06VI; -.
PhylomeDB; P28285; -.
Reactome; R-DME-390666; Serotonin receptors.
Reactome; R-DME-418594; G alpha (i) signalling events.
GenomeRNAi; 37196; -.
PRO; PR:P28285; -.
Proteomes; UP000000803; Chromosome 2R.
Bgee; FBgn0004168; -.
ExpressionAtlas; P28285; differential.
Genevisible; P28285; DM.
GO; GO:0016021; C:integral component of membrane; ISS:FlyBase.
GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO; GO:0008227; F:G-protein coupled amine receptor activity; ISS:FlyBase.
GO; GO:0004993; F:G-protein coupled serotonin receptor activity; IDA:FlyBase.
GO; GO:0001586; F:Gi/o-coupled serotonin receptor activity; NAS:FlyBase.
GO; GO:0030594; F:neurotransmitter receptor activity; IBA:GO_Central.
GO; GO:0007198; P:adenylate cyclase-inhibiting serotonin receptor signaling pathway; IDA:FlyBase.
GO; GO:0007615; P:anesthesia-resistant memory; IDA:FlyBase.
GO; GO:0002121; P:inter-male aggressive behavior; IMP:FlyBase.
GO; GO:0008049; P:male courtship behavior; IMP:FlyBase.
GO; GO:0007208; P:phospholipase C-activating serotonin receptor signaling pathway; IDA:FlyBase.
GO; GO:0045187; P:regulation of circadian sleep/wake cycle, sleep; IMP:FlyBase.
GO; GO:0007210; P:serotonin receptor signaling pathway; IDA:FlyBase.
InterPro; IPR000276; GPCR_Rhodpsn.
InterPro; IPR017452; GPCR_Rhodpsn_7TM.
Pfam; PF00001; 7tm_1; 1.
PRINTS; PR00237; GPCRRHODOPSN.
SMART; SM01381; 7TM_GPCR_Srsx; 1.
PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
2: Evidence at transcript level;
Cell membrane; Complete proteome; Disulfide bond;
G-protein coupled receptor; Glycoprotein; Membrane; Polymorphism;
Receptor; Reference proteome; Transducer; Transmembrane;
Transmembrane helix.
CHAIN 1 834 5-hydroxytryptamine receptor 2A.
/FTId=PRO_0000068962.
TOPO_DOM 1 230 Extracellular. {ECO:0000250}.
TRANSMEM 231 253 Helical; Name=1. {ECO:0000250}.
TOPO_DOM 254 263 Cytoplasmic. {ECO:0000250}.
TRANSMEM 264 285 Helical; Name=2. {ECO:0000250}.
TOPO_DOM 286 300 Extracellular. {ECO:0000250}.
TRANSMEM 301 322 Helical; Name=3. {ECO:0000250}.
TOPO_DOM 323 341 Cytoplasmic. {ECO:0000250}.
TRANSMEM 342 364 Helical; Name=4. {ECO:0000250}.
TOPO_DOM 365 391 Extracellular. {ECO:0000250}.
TRANSMEM 392 413 Helical; Name=5. {ECO:0000250}.
TOPO_DOM 414 752 Cytoplasmic. {ECO:0000250}.
TRANSMEM 753 776 Helical; Name=6. {ECO:0000250}.
TOPO_DOM 777 785 Extracellular. {ECO:0000250}.
TRANSMEM 786 808 Helical; Name=7. {ECO:0000250}.
TOPO_DOM 809 834 Cytoplasmic. {ECO:0000250}.
COMPBIAS 108 136 Ala-rich.
COMPBIAS 707 723 Gln-rich.
CARBOHYD 68 68 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 97 97 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 161 161 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 175 175 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 183 183 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 194 194 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 203 203 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 209 209 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
DISULFID 299 378 {ECO:0000255|PROSITE-ProRule:PRU00521}.
VARIANT 29 32 Missing (in strain: CA-128).
{ECO:0000269|PubMed:15611167}.
VARIANT 46 46 E -> Q (in strain: NC-066).
{ECO:0000269|PubMed:15611167}.
VARIANT 49 49 E -> V (in strain: NC-036 and NC-123).
{ECO:0000269|PubMed:15611167}.
VARIANT 51 51 D -> E (in strain: CA-002, CA-008, CA-
009, CA-011, CA-013, CA-015, CA-026, CA-
031, CA-033, CA-034, CA-035, CA-037, CA-
040, CA-048, CA-052, CA-055, CA-057, CA-
060, CA-061, CA-063, CA-064, CA-065, CA-
069, CA-072, CA-073, CA-075, CA-088, CA-
090, CA-093, CA-096, CA-100, CA-114, CA-
120, CA-127, CA-129, CA-132, CA-133, CA-
140, CA-142, CA-145, CA-147, NC-003, NC-
006, NC-010, NC-011, NC-014, NC-015, NC-
021, NC-033, NC-034, NC-036, NC-040, NC-
042, NC-044, NC-046, NC-047, NC-051, NC-
052, NC-054, NC-057, NC-066, NC-069, NC-
071, NC-073, NC-081, NC-084, NC-086, NC-
089, NC-092, NC-094, NC-096, NC-097, NC-
101, NC-103, NC-104, NC-107, NC-108, NC-
118, NC-119, NC-121, NC-123, NC-127, NC-
128, NC-129, NC-134, NC-136, NC-137, NC-
138, NC-141, NC-144 and NC-148).
{ECO:0000269|PubMed:15611167}.
VARIANT 52 52 D -> E (in strain: NC-103 and NC-118).
{ECO:0000269|PubMed:15611167}.
VARIANT 54 54 A -> G (in strain: NC-061).
{ECO:0000269|PubMed:15611167}.
VARIANT 76 76 S -> T (in strain: NC-012, NC-023, NC-
037, NC-038, NC-039, NC-124 and NC-131).
{ECO:0000269|PubMed:15611167}.
VARIANT 86 86 S -> T (in strain: CA-008, CA-009, CA-
013, CA-026, CA-031, CA-033, CA-035, CA-
037, CA-040, CA-048, CA-052, CA-057, CA-
060, CA-061, CA-063, CA-065, CA-072, CA-
073, CA-088, CA-093, CA-096, CA-100, CA-
114, CA-120, CA-129, CA-132, CA-133, CA-
140, CA-147, NC-011, NC-015, NC-021, NC-
033, NC-034, NC-040, NC-042, NC-044, NC-
046, NC-047, NC-051, NC-052, NC-054, NC-
057, NC-069, NC-084, NC-089, NC-092, NC-
094, NC-097, NC-103, NC-107, NC-119, NC-
121, NC-127, NC-128, NC-129, NC-134, NC-
137, NC-138, NC-141, NC-144 and NC-148).
{ECO:0000269|PubMed:15611167}.
VARIANT 91 91 P -> Q (in strain: CA-030, CA-068, CA-
091, NC-008, NC-025, NC-043, NC-048, NC-
060, NC-075, NC-088, NC-091, NC-114, NC-
116 and NC-135).
{ECO:0000269|PubMed:15611167}.
VARIANT 96 96 V -> A (in strain: CA-008, CA-009, CA-
011, CA-013, CA-015, CA-026, CA-031, CA-
033, CA-034, CA-035, CA-037, CA-040, CA-
048, CA-052, CA-055, CA-057, CA-060, CA-
061, CA-063, CA-064, CA-065, CA-069, CA-
072, CA-073, CA-075, CA-088, CA-090, CA-
093, CA-095, CA-096, CA-100, CA-114, CA-
120, CA-129, CA-132, CA-133, CA-140, CA-
147, NC-010, NC-011, NC-012, NC-014, NC-
015, NC-021, NC-023, NC-033, NC-034, NC-
036, NC-037, NC-038, NC-039, NC-040, NC-
042, NC-044, NC-046, NC-047, NC-051, NC-
052, NC-054, NC-057, NC-066, NC-069, NC-
073, NC-081, NC-084, NC-086, NC-089, NC-
092, NC-094, NC-096, NC-097, NC-101, NC-
103, NC-104, NC-107, NC-108, NC-118, NC-
119, NC-121, NC-123, NC-124, NC-127, NC-
128, NC-129, NC-131, NC-134, NC-136, NC-
137, NC-138, NC-141, NC-144, NC-148 and
Oregon-R). {ECO:0000269|PubMed:1310937,
ECO:0000269|PubMed:15611167}.
VARIANT 143 143 A -> T (in strain: CA-064).
{ECO:0000269|PubMed:15611167}.
VARIANT 146 146 S -> T (in strain: CA-008, CA-026, CA-
033, CA-035, CA-037, CA-048, CA-052, CA-
057, CA-060, CA-063, CA-065, CA-072, CA-
088, CA-090, CA-096, CA-100, CA-114, CA-
120, CA-132, CA-140, CA-147, NC-011, NC-
014, NC-033, NC-034, NC-040, NC-042, NC-
044, NC-046, NC-047, NC-051, NC-052, NC-
054, NC-057, NC-069, NC-084, NC-092, NC-
094, NC-096, NC-103, NC-105, NC-107, NC-
108, NC-118, NC-119, NC-121, NC-125, NC-
126, NC-127, NC-129, NC-138, NC-144 and
NC-148). {ECO:0000269|PubMed:15611167}.
VARIANT 171 171 A -> V (in strain: CA-008, CA-009, CA-
026, CA-031, CA-033, CA-035, CA-037, CA-
048, CA-052, CA-057, CA-060, CA-061, CA-
063, CA-065, CA-072, CA-088, CA-096, CA-
100, CA-114, CA-120, CA-132, CA-140, CA-
147, NC-011, NC-034, NC-040, NC-042, NC-
044, NC-046, NC-047, NC-051, NC-052, NC-
054, NC-057, NC-069, NC-084, NC-092, NC-
094, NC-103, NC-107, NC-119, NC-121, NC-
127, NC-129, NC-138, NC-144 and NC-148).
{ECO:0000269|PubMed:15611167}.
VARIANT 182 182 G -> D (in strain: NC-066).
{ECO:0000269|PubMed:15611167}.
VARIANT 184 184 D -> Y (in strain: NC-086, NC-104 and NC-
010). {ECO:0000269|PubMed:15611167}.
VARIANT 196 196 S -> N (in strain: NC-114).
{ECO:0000269|PubMed:1310937,
ECO:0000269|PubMed:15611167}.
VARIANT 198 198 Q -> H (in strain: CA-001, CA-009, CA-
011, CA-013, CA-015, CA-026, CA-030, CA-
031, CA-033, CA-034, CA-035, CA-037, CA-
040, CA-046, CA-048, CA-052, CA-055, CA-
057, CA-060, CA-061, CA-063, CA-065, CA-
066, CA-068, CA-069, CA-072, CA-073, CA-
075, CA-088, CA-090, CA-091, CA-093, CA-
095, CA-096, CA-100, CA-114, CA-120, CA-
132, CA-133, CA-140, CA-147, NC-008, NC-
011, NC-014, NC-015, NC-025, NC-034, NC-
040, NC-042, NC-043, NC-044, NC-046, NC-
047, NC-048, NC-051, NC-052, NC-054, NC-
057, NC-060, NC-066, NC-069, NC-073, NC-
075, NC-081, NC-084, NC-088, NC-091, NC-
092, NC-094, NC-096, NC-101, NC-103, NC-
107, NC-108, NC-110, NC-113, NC-114, NC-
115, NC-116, NC-118, NC-119, NC-121, NC-
123, NC-127, NC-128, NC-129, NC-135, NC-
136, NC-137, NC-138, NC-139, NC-142, NC-
144, NC-146, NC-148 and Oregon-R).
{ECO:0000269|PubMed:15611167}.
VARIANT 213 213 S -> G (in strain: CA-015).
{ECO:0000269|PubMed:15611167}.
VARIANT 531 531 Q -> L (in strain: NC-104).
{ECO:0000269|PubMed:15611167}.
VARIANT 536 536 T -> A (in strain: CA-011, CA-017, CA-
018, CA-062, CA-130, NC-118, NC-022, NC-
026, NC-049 and NC-073).
{ECO:0000269|PubMed:15611167}.
VARIANT 547 550 APSG -> GPMGPL (in strain: CA-013, CA-026
and CA-093).
{ECO:0000269|PubMed:15611167}.
VARIANT 571 571 E -> V (in strain: CA-002, CA-003, CA-
008, CA-011, CA-012, CA-015, CA-023, CA-
027, CA-030, CA-031, CA-034, CA-035, CA-
037, CA-043, CA-044, CA-045, CA-046, CA-
048, CA-052, CA-055, CA-057, CA-058, CA-
063, CA-064, CA-065, CA-066, CA-068, CA-
070, CA-072, CA-073, CA-075, CA-081, CA-
083, CA-087, CA-088, CA-089, CA-091, CA-
096, CA-100, CA-105, CA-114, CA-120, CA-
123, CA-128, CA-129, CA-133, CA-140, CA-
145, CA-147, CA-148, NC-001, NC-002, NC-
003, NC-010, NC-011, NC-012, NC-013, NC-
015, NC-023, NC-024, NC-025, NC-027, NC-
028, NC-029, NC-030, NC-032, NC-033, NC-
034, NC-036, NC-040, NC-041, NC-042, NC-
043, NC-044, NC-046, NC-047, NC-048, NC-
050, NC-051, NC-052, NC-054, NC-057, NC-
059, NC-060, NC-061, NC-066, NC-069, NC-
071, NC-072, NC-074, NC-075, NC-077, NC-
079, NC-080, NC-081, NC-084, NC-086, NC-
087, NC-088, NC-089, NC-091, NC-092, NC-
094, NC-098, NC-101, NC-103, NC-104, NC-
107, NC-109, NC-110, NC-111, NC-112, NC-
113, NC-114, NC-115, NC-116, NC-119, NC-
121, NC-124, NC-127, NC-128, NC-129, NC-
131, NC-133, NC-134, NC-135, NC-136, NC-
137, NC-138, NC-144, NC-146, NC-147, NC-
148 and NC-149).
{ECO:0000269|PubMed:15611167}.
VARIANT 585 585 T -> K (in strain: NC-026).
{ECO:0000269|PubMed:15611167}.
VARIANT 588 588 T -> M (in strain: Berkeley, CA-009, CA-
010, CA-013, CA-026, CA-041, CA-060, CA-
063, CA-066, CA-086, CA-093, CA-113, CA-
137, CA-145, NC-006, NC-008, NC-021, NC-
064, NC-067, NC-123, NC-142 and NC-150).
{ECO:0000269|PubMed:10731132,
ECO:0000269|PubMed:15611167,
ECO:0000269|Ref.4}.
VARIANT 589 589 T -> R (in strain: CA-040, CA-056, CA-
115, CA-118, CA-126, CA-132, CA-142, NC-
005, NC-037, NC-038, NC-039, NC-053, NC-
068, NC-095, NC-100, NC-105, NC-125, NC-
126 and NC-139).
{ECO:0000269|PubMed:15611167}.
VARIANT 648 648 A -> V (in strain: CA-023, CA-048, NC-
015, NC-110, NC-128, NC-133 and NC-137).
{ECO:0000269|PubMed:15611167}.
VARIANT 657 657 Q -> P (in strain: CA-130).
{ECO:0000269|PubMed:15611167}.
VARIANT 682 682 S -> W (in strain: CA-043, CA-058 and CA-
105). {ECO:0000269|PubMed:15611167}.
VARIANT 688 688 T -> I (in strain: CA-088).
{ECO:0000269|PubMed:15611167}.
VARIANT 692 692 S -> T (in strain: NC-104).
{ECO:0000269|PubMed:15611167}.
VARIANT 706 706 P -> T (in strain: NC-001).
{ECO:0000269|PubMed:15611167}.
VARIANT 716 718 Missing (in strain: NC-118).
{ECO:0000269|PubMed:15611167}.
VARIANT 716 717 Missing (in strain: CA-002, CA-009, CA-
010, CA-011, CA-017, CA-018, CA-023, CA-
030, CA-031, CA-037, CA-040, CA-041, CA-
044, CA-045, CA-047, CA-048, CA-052, CA-
056, CA-057, CA-062, CA-068, CA-070, CA-
075, CA-086, CA-087, CA-088, CA-089, CA-
091, CA-095, CA-096, CA-100, CA-113, CA-
114, CA-115, CA-118, CA-120, CA-126, CA-
127, CA-129, CA-132, CA-133, CA-136, CA-
140, CA-142, CA-145, CA-147, NC-001, NC-
003, NC-004, NC-005, NC-011, NC-015, NC-
017, NC-021, NC-022, NC-025, NC-033, NC-
034, NC-036, NC-037, NC-038, NC-039, NC-
040, NC-042, NC-044, NC-046, NC-048, NC-
049, NC-051, NC-052, NC-053, NC-054, NC-
057, NC-059, NC-068, NC-069, NC-070, NC-
071, NC-079, NC-080, NC-084, NC-086, NC-
087, NC-088, NC-089, NC-091, NC-092, NC-
094, NC-095, NC-100, NC-101, NC-104, NC-
105, NC-107, NC-109, NC-110, NC-111, NC-
112, NC-113, NC-114, NC-115, NC-116, NC-
119, NC-121, NC-123, NC-125, NC-126, NC-
128, NC-129, NC-133, NC-134, NC-135, NC-
136, NC-137, NC-138, NC-139, NC-142, NC-
144, NC-146, NC-147, NC-148, NC-149 and
NC-150). {ECO:0000269|PubMed:15611167}.
VARIANT 716 716 Q -> H (in strain: NC-032).
{ECO:0000269|PubMed:15611167}.
VARIANT 716 716 Q -> QH (in strain: NC-047).
VARIANT 717 719 QQQ -> H (in strain: CA-069, NC-096 and
NC-108). {ECO:0000269|PubMed:15611167}.
CONFLICT 135 135 R -> W (in Ref. 1; CAA77570).
{ECO:0000305}.
CONFLICT 400 400 L -> M (in Ref. 1; CAA77570).
{ECO:0000305}.
CONFLICT 813 813 R -> Q (in Ref. 4; AAY84887).
{ECO:0000305}.
SEQUENCE 834 AA; 89521 MW; D3E27389921BD04F CRC64;
MAHETSFNDA LDYIYIANSM NDRAFLIAEP HPEQPNVDGQ DQDDAELEEL DDMAVTDDGQ
LEDTNNNNNS KRYYSSGKRR ADFIGSLALK PPPTDVNTTT TTAGSPLATA ALAAAAASAS
VAAAAARITA KAAHRALTTK QDATSSPASS PALQLIDMDN NYTNVAVGLG AMLLNDTLLL
EGNDSSLFGE MLANRSGQLD LINGTGGLNV TTSKVAEDDF TQLLRMAVTS VLLGLMILVT
IIGNVFVIAA IILERNLQNV ANYLVASLAV ADLFVACLVM PLGAVYEISQ GWILGPELCD
IWTSCDVLCC TASILHLVAI AVDRYWAVTN IDYIHSRTSN RVFMMIFCVW TAAVIVSLAP
QFGWKDPDYL QRIEQQKCMV SQDVSYQVFA TCCTFYVPLL VILALYWKIY QTARKRIHRR
RPRPVDAAVN NNQPDGGAAT DTKLHRLRLR LGRFSTAKSK TGSAVGVSGP ASGGRALGLV
DGNSTNTVNT VEDTEFSSSN VDSKSRAGVE APSTSGNQIA TVSHLVALAK QQGKSTAKSS
AAVNGMAPSG RQEDDGQRPE HGEQEDREEL EDQDEQVGPQ PTTATSATTA AGTNESEDQC
KANGVEVLED PQLQQQLEQV QQLQKSVKSG GGGGASTSNA TTITSISALS PQTPTSQGVG
IAAAAAGPMT AKTSTLTSCN QSHPLCGTAN ESPSTPEPRS RQPTTPQQQP HQQAHQQQQQ
QQQLSSIANP MQKVNKRKET LEAKRERKAA KTLAIITGAF VVCWLPFFVM ALTMPLCAAC
QISDSVASLF LWLGYFNSTL NPVIYTIFSP EFRQAFKRIL FGGHRPVHYR SGKL


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