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AAEL000965-PA

 Q17MM7_AEDAE            Unreviewed;       812 AA.
Q17MM7;
25-JUL-2006, integrated into UniProtKB/TrEMBL.
25-JUL-2006, sequence version 1.
25-APR-2018, entry version 82.
SubName: Full=AAEL000965-PA {ECO:0000313|EMBL:EAT47994.1};
Name=5567489 {ECO:0000313|VectorBase:AAEL000965-PA};
ORFNames=AAEL000965 {ECO:0000313|EMBL:EAT47994.1};
Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
Culicidae; Culicinae; Aedini; Aedes; Stegomyia.
NCBI_TaxID=7159 {ECO:0000313|EMBL:EAT47994.1, ECO:0000313|Proteomes:UP000008820};
[1] {ECO:0000313|EMBL:EAT47994.1}
NUCLEOTIDE SEQUENCE.
STRAIN=Liverpool {ECO:0000313|EMBL:EAT47994.1};
Loftus B.J., Nene V.M., Hannick L.I., Bidwell S., Haas B., Amedeo P.,
Orvis J., Wortman J.R., White O.R., Salzberg S., Shumway M., Koo H.,
Zhao Y., Holmes M., Miller J., Schatz M., Pop M., Pai G.,
Utterback T., Rogers Y.-H., Kravitz S., Fraser C.M.;
Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|EMBL:EAT47994.1, ECO:0000313|Proteomes:UP000008820, ECO:0000313|VectorBase:AAEL000965-PA}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Liverpool {ECO:0000313|EMBL:EAT47994.1}, and
Liverpool/LVPib12 {ECO:0000313|Proteomes:UP000008820,
ECO:0000313|VectorBase:AAEL000965-PA};
PubMed=17510324; DOI=10.1126/science.1138878;
Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M.,
Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J.,
Sinkins S.P., Hogenkamp D.G., Amedeo P., Arensburger P.,
Atkinson P.W., Bidwell S.L., Biedler J., Birney E., Bruggner R.V.,
Costas J., Coy M.R., Crabtree J., Crawford M., DeBruyn B.,
DeCaprio D., Eiglmeier K., Eisenstadt E., El-Dorry H., Gelbart W.M.,
Gomes S.L., Hammond M., Hannick L.I., Hogan J.R., Holmes M.H.,
Jaffe D., Johnston S.J., Kennedy R.C., Koo H., Kravitz S.,
Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S., Lovin D.D.,
Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P., Mori A.,
Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D.,
White O.R., Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A.,
Raikhel A.S., Soares M.B., Knudson D.L., Lee N.H., Galagan J.,
Salzberg S.L., Paulsen I.T., Dimopoulos G., Collins F.H., Bruce B.,
Fraser-Liggett C.M., Severson D.W.;
"Genome sequence of Aedes aegypti, a major arbovirus vector.";
Science 316:1718-1723(2007).
[3] {ECO:0000313|EMBL:EAT47994.1}
NUCLEOTIDE SEQUENCE.
STRAIN=Liverpool {ECO:0000313|EMBL:EAT47994.1};
VectorBase;
Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
[4] {ECO:0000313|VectorBase:AAEL000965-PA}
IDENTIFICATION.
STRAIN=Liverpool/LVPib12 {ECO:0000313|VectorBase:AAEL000965-PA};
VectorBase;
Submitted (FEB-2017) to UniProtKB.
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EMBL; CH477204; EAT47994.1; -; Genomic_DNA.
RefSeq; XP_001657496.1; XM_001657446.1.
ProteinModelPortal; Q17MM7; -.
STRING; 7159.AAEL000965-PA; -.
EnsemblMetazoa; AAEL000965-RA; AAEL000965-PA; AAEL000965.
GeneID; 5567489; -.
KEGG; aag:5567489; -.
VectorBase; AAEL000965-RA; AAEL000965-PA; AAEL000965.
eggNOG; ENOG410ITFZ; Eukaryota.
eggNOG; ENOG410XTIR; LUCA.
HOGENOM; HOG000229147; -.
InParanoid; Q17MM7; -.
OMA; DMEWINT; -.
OrthoDB; EOG091G03QU; -.
PhylomeDB; Q17MM7; -.
Proteomes; UP000008820; Unassembled WGS sequence.
GO; GO:0005623; C:cell; IEA:GOC.
GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
Gene3D; 2.120.10.30; -; 3.
InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
InterPro; IPR001258; NHL_repeat.
InterPro; IPR013017; NHL_repeat_subgr.
InterPro; IPR012336; Thioredoxin-like_fold.
InterPro; IPR036249; Thioredoxin-like_sf.
InterPro; IPR013766; Thioredoxin_domain.
Pfam; PF01436; NHL; 2.
Pfam; PF13905; Thioredoxin_8; 1.
SUPFAM; SSF52833; SSF52833; 1.
PROSITE; PS51125; NHL; 6.
PROSITE; PS51352; THIOREDOXIN_2; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000008820};
Reference proteome {ECO:0000313|Proteomes:UP000008820};
Signal {ECO:0000256|SAM:SignalP}.
SIGNAL 1 17 {ECO:0000256|SAM:SignalP}.
CHAIN 18 812 {ECO:0000256|SAM:SignalP}.
/FTId=PRO_5014308207.
DOMAIN 115 278 Thioredoxin.
{ECO:0000259|PROSITE:PS51352}.
REPEAT 321 342 NHL. {ECO:0000256|PROSITE-
ProRule:PRU00504}.
REPEAT 366 396 NHL. {ECO:0000256|PROSITE-
ProRule:PRU00504}.
REPEAT 416 432 NHL. {ECO:0000256|PROSITE-
ProRule:PRU00504}.
REPEAT 508 539 NHL. {ECO:0000256|PROSITE-
ProRule:PRU00504}.
REPEAT 571 602 NHL. {ECO:0000256|PROSITE-
ProRule:PRU00504}.
REPEAT 608 652 NHL. {ECO:0000256|PROSITE-
ProRule:PRU00504}.
SEQUENCE 812 AA; 90289 MW; 50A78549E966BD5F CRC64;
MVLFSFVFSL RGLLTTGGRL TARNVIEGST RHGHHRHQHH QCNQNKTFQK FLHDSSLLSP
VRDSRFPFPL TDRFRKSFKI GTRMSSSSPE SGDMLDYLAY NCSKLSNDLW EASGLSEKRK
LVAEYLKNAD REGKSIRDFK EGLDWFNVTE PLSFDGCLRG KIVVLDFFTY CCINCMHILP
DLKRLEHLYS VEDGLVVIGV HSAKFENEKD SANILSAVQR YEISHPVVND NVSSMWRNLR
VQCWPTLMIL GPRANPLFVI MGEGHFDDLK LYVSSALKFY KDKGAILGHT LPINVATNLI
ETSHLQFPGK ISSSYRGGDN TDNCLYAISD SGNHRILVVN SDGLILYRIG GKRAGFVDGD
FRKARFNAPQ GVAFQNDTTL FVADNENHAI RKIDLKSQQV TTVVGNGQQG CDRIGGKIGR
DQILSSPWDV AVYRTKDLDM SFHADESKTP LKDVVFIAMA GIHQIWALFL EDTIWWKFKK
YSAGSCLAIA GNGREENRNN SYPNNAAFSQ PSGLAINKDA KEIYLADSES SSVRKMSLSD
GKVLAVAGGD RNPLDLFSFG DIDGKQYSAK FQHPLGVAYN SKDNCIYVAD TYNHKIKKIN
ASTNVATTCS FQDESGSTKQ FNEPAGLCLD PTGRFLYIAD TNNHQIMIAD LSDNIIRPLK
VRFNNSEADQ LDNPGETYLY ENTFKVLPEG GKVVLTLEFG YLESNVKLTQ GAPQKWSLTL
PSDKWRCDTM NGSISSLNDG LSLTLVVPKG SEQQKPVLGT VNFKLNLCAN DVCFPKEFAV
GLNFAYDVTG GSTVKGSLMV QVGRNNVVVS KE


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