Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

ALA-interacting subunit 1 (AtALIS1) (ALA3 beta-subunit 1)

 ALIS1_ARATH             Reviewed;         350 AA.
Q9LTW0;
24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
01-OCT-2000, sequence version 1.
25-APR-2018, entry version 93.
RecName: Full=ALA-interacting subunit 1;
Short=AtALIS1;
AltName: Full=ALA3 beta-subunit 1;
Name=ALIS1; OrderedLocusNames=At3g12740; ORFNames=MBK21.12;
Arabidopsis thaliana (Mouse-ear cress).
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
Arabidopsis.
NCBI_TaxID=3702;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
PubMed=10819329; DOI=10.1093/dnares/7.2.131;
Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
"Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
features of the regions of 4,504,864 bp covered by sixty P1 and TAC
clones.";
DNA Res. 7:131-135(2000).
[2]
GENOME REANNOTATION.
STRAIN=cv. Columbia;
PubMed=27862469; DOI=10.1111/tpj.13415;
Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
Town C.D.;
"Araport11: a complete reannotation of the Arabidopsis thaliana
reference genome.";
Plant J. 89:789-804(2017).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
PubMed=14593172; DOI=10.1126/science.1088305;
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J.,
Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F.,
Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.,
Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J.,
Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y.,
Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P.,
Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F.,
Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M.,
Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J.,
Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T.,
Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y.,
Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis
genome.";
Science 302:842-846(2003).
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
Feldmann K.A.;
"Full-length cDNA from Arabidopsis thaliana.";
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
[5]
FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND INTERACTION
WITH ALA3.
PubMed=18344284; DOI=10.1105/tpc.107.054767;
Poulsen L.R., Lopez-Marques R.L., McDowell S.C., Okkeri J., Licht D.,
Schulz A., Pomorski T., Harper J.F., Palmgren M.G.;
"The Arabidopsis P4-ATPase ALA3 localizes to the Golgi and requires a
beta-subunit to function in lipid translocation and secretory vesicle
formation.";
Plant Cell 20:658-676(2008).
[6]
FUNCTION, SUBCELLULAR LOCATION, AND INTERACTION WITH ALA2 AND ALA3.
PubMed=20053675; DOI=10.1091/mbc.E09-08-0656;
Lopez-Marques R.L., Poulsen L.R., Hanisch S., Meffert K.,
Buch-Pedersen M.J., Jakobsen M.K., Pomorski T.G., Palmgren M.G.;
"Intracellular targeting signals and lipid specificity determinants of
the ALA/ALIS P4-ATPase complex reside in the catalytic ALA alpha-
subunit.";
Mol. Biol. Cell 21:791-801(2010).
[7]
ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, CLEAVAGE OF INITIATOR
METHIONINE [LARGE SCALE ANALYSIS], AND IDENTIFICATION BY MASS
SPECTROMETRY [LARGE SCALE ANALYSIS].
PubMed=22223895; DOI=10.1074/mcp.M111.015131;
Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C.,
Meinnel T., Giglione C.;
"Comparative large-scale characterisation of plant vs. mammal proteins
reveals similar and idiosyncratic N-alpha acetylation features.";
Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012).
-!- FUNCTION: Required for the lipid transport activity of the
ALA/ALIS P4-ATPase complex. {ECO:0000269|PubMed:18344284,
ECO:0000269|PubMed:20053675}.
-!- SUBUNIT: Associates with ALA3 to form a stable complex. Interacts
with ALA2 in a heterologous system. {ECO:0000269|PubMed:18344284,
ECO:0000269|PubMed:20053675}.
-!- SUBCELLULAR LOCATION: Golgi apparatus membrane; Multi-pass
membrane protein. Prevacuolar compartment membrane; Multi-pass
membrane protein. Endoplasmic reticulum membrane; Multi-pass
membrane protein. Note=In a heterologous system, the final
intracellular localization after exit from the endoplasmic
reticulum is the prevacuolar compartment in the presence of ALA2
and the Golgi in the presence of ALA3.
-!- TISSUE SPECIFICITY: Expressed in roots, leaves, stems, flowers and
siliques. Found in petals and sepals, but not in reproductive
tissues. In siliques, detected in the upper part of the seed pod
and in the area between the seed pod and the stem, but not in
developing seeds. Strong expression in vascular shoot tissues and
in stomatal guard cells of young rosettes leaves. In roots,
expressed in cells surrounding the xylem and in central and
peripheral columella cells. {ECO:0000269|PubMed:18344284}.
-!- SIMILARITY: Belongs to the CDC50/LEM3 family. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; AB024033; BAB02418.1; -; Genomic_DNA.
EMBL; CP002686; AEE75241.1; -; Genomic_DNA.
EMBL; AY045904; AAK76578.1; -; mRNA.
EMBL; AF410309; AAK95295.1; -; mRNA.
EMBL; AY091210; AAM14149.1; -; mRNA.
EMBL; AY087607; AAM65148.1; -; mRNA.
RefSeq; NP_566435.1; NM_112110.4.
UniGene; At.21212; -.
UniGene; At.48651; -.
STRING; 3702.AT3G12740.1; -.
TCDB; 8.A.27.1.4; the cdc50 p-type atpase lipid flippase subunit (cdc50) family.
iPTMnet; Q9LTW0; -.
PaxDb; Q9LTW0; -.
PRIDE; Q9LTW0; -.
EnsemblPlants; AT3G12740.1; AT3G12740.1; AT3G12740.
GeneID; 820456; -.
Gramene; AT3G12740.1; AT3G12740.1; AT3G12740.
KEGG; ath:AT3G12740; -.
Araport; AT3G12740; -.
TAIR; locus:2087695; AT3G12740.
eggNOG; KOG2952; Eukaryota.
eggNOG; COG5035; LUCA.
HOGENOM; HOG000209056; -.
InParanoid; Q9LTW0; -.
OMA; NDDFIVW; -.
OrthoDB; EOG09360FGO; -.
PhylomeDB; Q9LTW0; -.
Reactome; R-ATH-6798695; Neutrophil degranulation.
PRO; PR:Q9LTW0; -.
Proteomes; UP000006548; Chromosome 3.
ExpressionAtlas; Q9LTW0; baseline and differential.
Genevisible; Q9LTW0; AT.
GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO; GO:0005794; C:Golgi apparatus; IDA:TAIR.
GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO; GO:0015914; P:phospholipid transport; IDA:TAIR.
InterPro; IPR005045; CDC50/LEM3_fam.
PANTHER; PTHR10926; PTHR10926; 1.
Pfam; PF03381; CDC50; 1.
PIRSF; PIRSF015840; DUF284_TM_euk; 1.
1: Evidence at protein level;
Acetylation; Complete proteome; Endoplasmic reticulum; Glycoprotein;
Golgi apparatus; Membrane; Reference proteome; Transmembrane;
Transmembrane helix.
INIT_MET 1 1 Removed. {ECO:0000244|PubMed:22223895}.
CHAIN 2 350 ALA-interacting subunit 1.
/FTId=PRO_0000366954.
TRANSMEM 51 71 Helical. {ECO:0000255}.
TRANSMEM 305 325 Helical. {ECO:0000255}.
COMPBIAS 11 14 Poly-Ala.
MOD_RES 2 2 N-acetylserine.
{ECO:0000244|PubMed:22223895}.
CARBOHYD 105 105 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 182 182 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 224 224 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
SEQUENCE 350 AA; 39069 MW; 8B2BCDA56D82B1A6 CRC64;
MSSSNTPSSS AAAAGSIDSS AARRNSKRPK YSKFTQQELP ACKPILTPGW VISTFLIISV
IFIPLGVISL FASQDVVEIV DRYDSACIPL SDRANKVAYI QGTGNKSCTR TLIVPKRMKQ
PIYVYYQLEN FYQNHRRYVK SRSDSQLRSV KDENQIDACK PEDDFGGQPI VPCGLIAWSL
FNDTYVLSRN NQGLTVNKKG IAWKSDKEHK FGKNVFPKNF QKGNLTGGAS LDPNKPLSDQ
EDLIVWMRTA ALPTFRKLYG KIESDLEKGE NIQVTLQNNY NTYSFSGKKK LVLSTTSWLG
GKNDFLGIAY LTVGGICFVL ALAFTVMYLV KPRRLGDPTY LSWNRIPGGR


Related products :

Catalog number Product name Quantity
EIAAB29611 Homo sapiens,Human,PAF acetylhydrolase 30 kDa subunit,PAF-AH 30 kDa subunit,PAFAH subunit beta,PAF-AH subunit beta,PAFAH1B2,PAFAHB,Platelet-activating factor acetylhydrolase IB subunit beta
EIAAB29614 Bos taurus,Bovine,PAF acetylhydrolase 30 kDa subunit,PAF-AH 30 kDa subunit,PAFAH subunit beta,PAF-AH subunit beta,PAFAH1B2,PAFAHB,Platelet-activating factor acetylhydrolase IB subunit beta
EIAAB29612 Mouse,Mus musculus,PAF acetylhydrolase 30 kDa subunit,PAF-AH 30 kDa subunit,PAFAH subunit beta,PAF-AH subunit beta,Pafah1b2,Pafahb,Platelet-activating factor acetylhydrolase IB subunit beta
EIAAB27268 Mouse,Mus musculus,Na(+)_K(+)-transporting ATPase subunit beta-1-interacting protein 2,Nkain2,Sodium_potassium-transporting ATPase subunit beta-1-interacting protein 2,Tcba1,T-cell lymphoma breakpoint
E1761h ELISA kit Homo sapiens,Human,IL-31 receptor subunit beta,IL-31R subunit beta,IL-31RB,IL-31R-beta,Interleukin-31 receptor subunit beta,Oncostatin-M-specific receptor subunit beta,OSMR,OSMRB 96T
U1761h CLIA Homo sapiens,Human,IL-31 receptor subunit beta,IL-31R subunit beta,IL-31RB,IL-31R-beta,Interleukin-31 receptor subunit beta,Oncostatin-M-specific receptor subunit beta,OSMR,OSMRB 96T
E1761h ELISA Homo sapiens,Human,IL-31 receptor subunit beta,IL-31R subunit beta,IL-31RB,IL-31R-beta,Interleukin-31 receptor subunit beta,Oncostatin-M-specific receptor subunit beta,OSMR,OSMRB 96T
EIAAB29613 Chicken,Gallus gallus,PAF acetylhydrolase 30 kDa subunit,PAF-AH 30 kDa subunit,PAFAH subunit beta,PAF-AH subunit beta,PAFAH1B2,PAFAHB,Platelet-activating factor acetylhydrolase IB subunit beta,RCJMB04
E1761r ELISA kit IL-31 receptor subunit beta,IL-31R subunit beta,IL-31RB,IL-31R-beta,Interleukin-31 receptor subunit beta,Oncostatin-M-specific receptor subunit beta,Osmr,Osmrb,Rat,Rattus norvegicus 96T
U1761r CLIA IL-31 receptor subunit beta,IL-31R subunit beta,IL-31RB,IL-31R-beta,Interleukin-31 receptor subunit beta,Oncostatin-M-specific receptor subunit beta,Osmr,Osmrb,Rat,Rattus norvegicus 96T
E1761m ELISA kit IL-31 receptor subunit beta,IL-31R subunit beta,IL-31RB,IL-31R-beta,Interleukin-31 receptor subunit beta,Mouse,Mus musculus,Oncostatin-M-specific receptor subunit beta,Osmr,Osmrb 96T
E1761m ELISA IL-31 receptor subunit beta,IL-31R subunit beta,IL-31RB,IL-31R-beta,Interleukin-31 receptor subunit beta,Mouse,Mus musculus,Oncostatin-M-specific receptor subunit beta,Osmr,Osmrb 96T
E1761r ELISA IL-31 receptor subunit beta,IL-31R subunit beta,IL-31RB,IL-31R-beta,Interleukin-31 receptor subunit beta,Oncostatin-M-specific receptor subunit beta,Osmr,Osmrb,Rat,Rattus norvegicus 96T
U1761m CLIA IL-31 receptor subunit beta,IL-31R subunit beta,IL-31RB,IL-31R-beta,Interleukin-31 receptor subunit beta,Mouse,Mus musculus,Oncostatin-M-specific receptor subunit beta,Osmr,Osmrb 96T
15-288-22423F Platelet-activating factor acetylhydrolase IB subunit beta - EC 3.1.1.47; PAF acetylhydrolase 30 kDa subunit; PAF-AH 30 kDa subunit; PAF-AH subunit beta; PAFAH subunit beta Polyclonal 0.05 mg
15-288-22423F Platelet-activating factor acetylhydrolase IB subunit beta - EC 3.1.1.47; PAF acetylhydrolase 30 kDa subunit; PAF-AH 30 kDa subunit; PAF-AH subunit beta; PAFAH subunit beta Polyclonal 0.1 mg
EIAAB09602 Alien homolog,COP9 signalosome complex subunit 2,Cops2,Csn2,JAB1-containing signalosome subunit 2,Mouse,Mus musculus,SGN2,Signalosome subunit 2,Thyroid receptor-interacting protein 15,TR-interacting p
EIAAB09601 Alien homolog,COP9 signalosome complex subunit 2,COPS2,CSN2,Homo sapiens,Human,JAB1-containing signalosome subunit 2,SGN2,Signalosome subunit 2,Thyroid receptor-interacting protein 15,TR-interacting p
E1837h ELISA High affinity IL-2 receptor subunit beta,Homo sapiens,Human,IL-2 receptor subunit beta,IL-2R subunit beta,IL2RB,IL-2RB,Interleukin-2 receptor subunit beta,p70-75,p75 96T
U1837h CLIA kit High affinity IL-2 receptor subunit beta,Homo sapiens,Human,IL-2 receptor subunit beta,IL-2R subunit beta,IL2RB,IL-2RB,Interleukin-2 receptor subunit beta,p70-75,p75 96T
E1837h ELISA kit High affinity IL-2 receptor subunit beta,Homo sapiens,Human,IL-2 receptor subunit beta,IL-2R subunit beta,IL2RB,IL-2RB,Interleukin-2 receptor subunit beta,p70-75,p75 96T
U1837h CLIA High affinity IL-2 receptor subunit beta,Homo sapiens,Human,IL-2 receptor subunit beta,IL-2R subunit beta,IL2RB,IL-2RB,Interleukin-2 receptor subunit beta,p70-75,p75 96T
10-288-22423F Platelet-activating factor acetylhydrolase IB subunit beta - EC 3.1.1.47; PAF acetylhydrolase 30 kDa subunit; PAF-AH 30 kDa subunit; PAF-AH subunit beta; PAFAH subunit beta 0.05 mg
10-288-22423F Platelet-activating factor acetylhydrolase IB subunit beta - EC 3.1.1.47; PAF acetylhydrolase 30 kDa subunit; PAF-AH 30 kDa subunit; PAF-AH subunit beta; PAFAH subunit beta 0.1 mg
EIAAB27267 Bos taurus,Bovine,Na(+)_K(+)-transporting ATPase subunit beta-1-interacting protein 2,NKAIN2,Sodium_potassium-transporting ATPase subunit beta-1-interacting protein 2


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur