Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

AP-4 complex accessory subunit Tepsin (ENTH domain-containing protein 2) (Tetra-epsin)

 AP4AT_RAT               Reviewed;         569 AA.
G3V8Y7; Q5EB78;
11-JUL-2012, integrated into UniProtKB/Swiss-Prot.
16-NOV-2011, sequence version 1.
18-JUL-2018, entry version 41.
RecName: Full=AP-4 complex accessory subunit Tepsin {ECO:0000305};
AltName: Full=ENTH domain-containing protein 2 {ECO:0000312|RGD:1307410};
AltName: Full=Tetra-epsin {ECO:0000303|PubMed:22472443};
Name=Tepsin {ECO:0000303|PubMed:22472443, ECO:0000312|RGD:1307410};
Synonyms=Enthd2 {ECO:0000312|RGD:1307410};
Rattus norvegicus (Rat).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Rattus.
NCBI_TaxID=10116;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 332-569.
TISSUE=Brain;
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
[3]
SUBCELLULAR LOCATION.
PubMed=22472443; DOI=10.1083/jcb.201111049;
Borner G.H., Antrobus R., Hirst J., Bhumbra G.S., Kozik P.,
Jackson L.P., Sahlender D.A., Robinson M.S.;
"Multivariate proteomic profiling identifies novel accessory proteins
of coated vesicles.";
J. Cell Biol. 197:141-160(2012).
[4]
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-400, AND IDENTIFICATION
BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
PubMed=22673903; DOI=10.1038/ncomms1871;
Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A.,
Lundby C., Olsen J.V.;
"Quantitative maps of protein phosphorylation sites across 14
different rat organs and tissues.";
Nat. Commun. 3:876-876(2012).
-!- FUNCTION: Associates with the adapter-like complex 4 (AP-4) and
may therefore play a role in vesicular trafficking of proteins at
the trans-Golgi network. {ECO:0000250|UniProtKB:Q96N21}.
-!- SUBUNIT: Interacts with AP4B1 and AP4E1; the interaction is direct
and mediates the association of TEPSIN with the adapter-like
complex 4 (AP-4), a heterotetramer composed of AP4B1, AP4E1, AP4M1
and AP4S1. {ECO:0000250|UniProtKB:Q96N21}.
-!- SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network
membrane {ECO:0000269|PubMed:22472443}; Peripheral membrane
protein {ECO:0000250|UniProtKB:Q96N21}. Cytoplasmic vesicle
{ECO:0000269|PubMed:22472443}. Cytoplasm, cytosol
{ECO:0000250|UniProtKB:Q96N21}. Note=Extensively colocalizes with
AP-4 which mediates the recruitment of TEPSIN to the trans-Golgi
network. {ECO:0000269|PubMed:22472443}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; CH473948; EDM06814.1; -; Genomic_DNA.
EMBL; BC089956; AAH89956.1; -; mRNA.
RefSeq; NP_001094199.1; NM_001100729.1.
UniGene; Rn.154667; -.
SMR; G3V8Y7; -.
STRING; 10116.ENSRNOP00000031142; -.
iPTMnet; G3V8Y7; -.
PhosphoSitePlus; G3V8Y7; -.
PaxDb; G3V8Y7; -.
Ensembl; ENSRNOT00000038993; ENSRNOP00000031142; ENSRNOG00000028161.
GeneID; 360673; -.
KEGG; rno:360673; -.
CTD; 146705; -.
RGD; 1307410; Tepsin.
eggNOG; ENOG410IEKN; Eukaryota.
eggNOG; ENOG410ZYSQ; LUCA.
GeneTree; ENSGT00390000015076; -.
HOGENOM; HOG000049246; -.
InParanoid; G3V8Y7; -.
OMA; QHFLKEC; -.
OrthoDB; EOG091G03PK; -.
TreeFam; TF331354; -.
PRO; PR:G3V8Y7; -.
Proteomes; UP000002494; Chromosome 10.
Bgee; ENSRNOG00000028161; -.
Genevisible; G3V8Y7; RN.
GO; GO:0030124; C:AP-4 adaptor complex; IEA:Ensembl.
GO; GO:0030662; C:coated vesicle membrane; IDA:UniProtKB.
GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
GO; GO:0031312; C:extrinsic component of organelle membrane; IEA:Ensembl.
GO; GO:0031965; C:nuclear membrane; IEA:Ensembl.
GO; GO:0016607; C:nuclear speck; IEA:Ensembl.
GO; GO:0032588; C:trans-Golgi network membrane; IEA:Ensembl.
CDD; cd03572; ENTH_epsin_related; 1.
Gene3D; 1.25.40.90; -; 1.
InterPro; IPR013809; ENTH.
InterPro; IPR035802; ENTH/VHS_tepsin.
InterPro; IPR008942; ENTH_VHS.
InterPro; IPR039273; TEPSIN.
PANTHER; PTHR21514; PTHR21514; 1.
Pfam; PF01417; ENTH; 1.
SUPFAM; SSF48464; SSF48464; 1.
1: Evidence at protein level;
Complete proteome; Cytoplasm; Cytoplasmic vesicle; Golgi apparatus;
Membrane; Phosphoprotein; Reference proteome.
CHAIN 1 569 AP-4 complex accessory subunit Tepsin.
/FTId=PRO_0000418126.
DOMAIN 8 141 ENTH.
REGION 525 535 Interaction with AP4B1.
{ECO:0000250|UniProtKB:Q96N21}.
REGION 559 569 Interaction with AP4E1.
{ECO:0000250|UniProtKB:Q96N21}.
COMPBIAS 260 292 Ser-rich.
MOD_RES 400 400 Phosphoserine.
{ECO:0000244|PubMed:22673903}.
SEQUENCE 569 AA; 60281 MW; BCFE523992D97CCA CRC64;
MAAVPPLRDR LSFLHRLPIL LKGTSDDDIP CPGYLFEEIA KISHESLGSS QCLLEYLLNR
LDSSSGHVKL KVLKILLYLC SHGSSSFMLI LRRNSALIQE ATAFAGPPDP LHGNSLYQKV
RAAAQDLGST LFSDALPQPP SQPPQILPPA GMGAQARPHS ALQGFGYTKE SSRTGSAGET
FLSTIQRAAE VVVNAVRPGP DNPCTKGPLP HGDAYQPAVT PSASHTHPNP GNLLPAAIQG
TRAVKHQPGQ AGGGWDEMDS SPSSQNSSCT SNLSRASDSV SRSGSDSHSG ASREPGDLAE
RAEGMAPNDC QQELNLVRTV TQGPRVFLSR EETQHFIKEC GLLNCEAVLE LLLQQLVGTS
ECEQMRALCA IASFGSADLL PQEHILLLCR QQLQELGAGS PGPVTNKATK ILRHLEASCG
QQFPTLRPCA QPNSAAAVVG PADLLTSPVP PPGSQVFLQP LSSTAVVPRS PVPTPSPDTL
PPALQDPGEL RTQLVCSSEP GTGSEQRLEN TDTPKDSSSP CPWSPNSLFA GMELVACTRL
PCPSFQADLQ KVTTEPPVSE PSAFAFLNM


Related products :

Catalog number Product name Quantity
EIAAB13009 ENTH domain-containing protein 1,ENTHD1,Epsin-2B,Homo sapiens,Human
EIAAB13138 Clathrin interactor 1,Clint1,Enth,Enthoprotin,Epn4,Epnr,Epsin-4,EpsinR,Epsin-related protein,Kiaa0171,Mouse,Mus musculus
EIAAB13137 Clathrin interactor 1,Clathrin-interacting protein localized in the trans-Golgi region,Clint,CLINT1,ENTH,Enthoprotin,EPN4,EPNR,Epsin-4,EpsinR,Epsin-related protein,Homo sapiens,Human,KIAA0171
15-288-21448A AP-3 complex subunit beta-2 - Adapter-related protein complex 3 beta-2 subunit; Beta3B-adaptin; Adaptor protein complex AP-3 beta-2 subunit; AP-3 complex beta-2 subunit; Clathrin assembly protein comp 0.1 mg
15-288-21448A AP-3 complex subunit beta-2 - Adapter-related protein complex 3 beta-2 subunit; Beta3B-adaptin; Adaptor protein complex AP-3 beta-2 subunit; AP-3 complex beta-2 subunit; Clathrin assembly protein comp 0.05 mg
EIAAB33312 Complex III subunit 8,Complex III subunit VIII,Cytochrome b-c1 complex subunit 8,Low molecular mass ubiquinone-binding protein,Qpc,Rat,Rattus norvegicus,Ubiquinol-cytochrome c reductase complex 9.5 kD
EIAAB33299 Complex III subunit 10,Complex III subunit XI,Cytochrome b-c1 complex subunit 10,Homo sapiens,Human,Ubiquinol-cytochrome c reductase complex 6.4 kDa protein,UQCR,UQCR11
EIAAB33310 Complex III subunit 7,Complex III subunit VII,Cytochrome b-c1 complex subunit 7,Homo sapiens,Human,QP-C,Ubiquinol-cytochrome c reductase complex 14 kDa protein,UQBP,UQCRB
26-141 NDUFC2 is the accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). It is believed to be not involved in catalysis reaction. Complex I functions in the tran 0.05 mg
EIAAB33300 Bos taurus,Bovine,Complex III subunit 10,Complex III subunit XI,Cytochrome b-c1 complex subunit 10,Ubiquinol-cytochrome c reductase complex 6.4 kDa protein,UQCR,UQCR11
EIAAB33298 Complex III subunit 10,Complex III subunit XI,Cytochrome b-c1 complex subunit 10,Mouse,Mus musculus,Ubiquinol-cytochrome c reductase complex 6.4 kDa protein,Uqcr,Uqcr11
EIAAB33317 Complex III subunit 9,Complex III subunit X,Cytochrome b-c1 complex subunit 9,Cytochrome c1 non-heme 7 kDa protein,Homo sapiens,HSPC119,Human,Ubiquinol-cytochrome c reductase complex 7.2 kDa protein,U
EIAAB45563 32 kDa accessory protein,ATP6D,ATP6V0D1,Homo sapiens,Human,p39,Vacuolar proton pump subunit d 1,V-ATPase 40 kDa accessory protein,V-ATPase AC39 subunit,V-ATPase subunit d 1,VPATPD,V-type proton ATPase
EIAAB45564 32 kDa accessory protein,ATP6D,ATP6V0D1,Bos taurus,Bovine,P39,Vacuolar proton pump subunit d 1,V-ATPase 40 kDa accessory protein,V-ATPase AC39 subunit,V-ATPase subunit d 1,VPATPD,V-type proton ATPase
EIAAB33311 Bos taurus,Bovine,Complex III subunit 7,Complex III subunit VII,Cytochrome b-c1 complex subunit 7,QP-C,Ubiquinol-cytochrome c reductase complex 14 kDa protein,UQCRB
EIAAB33309 Complex III subunit 7,Complex III subunit VII,Cytochrome b-c1 complex subunit 7,Mouse,Mus musculus,Ubiquinol-cytochrome c reductase complex 14 kDa protein,Uqcrb
EIAAB33318 Bos taurus,Bovine,Complex III subunit 9,Complex III subunit X,Cytochrome b-c1 complex subunit 9,Cytochrome c1 non-heme 7 kDa protein,Ubiquinol-cytochrome c reductase complex 7.2 kDa protein,UQCR10
EIAAB33316 Complex III subunit 9,Complex III subunit X,Cytochrome b-c1 complex subunit 9,Cytochrome c1 non-heme 7 kDa protein,Mouse,Mus musculus,Ubiquinol-cytochrome c reductase complex 7.2 kDa protein,Uqcr10
EIAAB12796 ELK4,ETS domain-containing protein Elk-4,Homo sapiens,Human,SAP1,SAP-1,Serum response factor accessory protein 1,SRF accessory protein 1
EIAAB10216 Bos taurus,Bovine,Complex III subunit 4,Complex III subunit IV,CYC1,Cytochrome b-c1 complex subunit 4,Cytochrome c-1,Cytochrome c1, heme protein, mitochondrial,Ubiquinol-cytochrome-c reductase complex
EIAAB12795 Elk4,ETS domain-containing protein Elk-4,Mouse,Mus musculus,Sap1,SAP-1,Serum response factor accessory protein 1,SRF accessory protein 1
EIAAB33305 Complex III subunit 6,Complex III subunit VIII,Cytochrome b-c1 complex subunit 6, mitochondrial,Cytochrome c1 non-heme 11 kDa protein,Homo sapiens,Human,Mitochondrial hinge protein,Ubiquinol-cytochrom
EIAAB33308 Complex III subunit 6,Complex III subunit VIII,Cytochrome b-c1 complex subunit 6, mitochondrial,Cytochrome c1 non-heme 11 kDa protein,Mitochondrial hinge protein,Mouse,Mus musculus,Ubiquinol-cytochrom
EIAAB33306 Complex III subunit 6,Complex III subunit VIII,Cytochrome b-c1 complex subunit 6, mitochondrial,Cytochrome c1 non-heme 11 kDa protein,Mitochondrial hinge protein,Rat,Rattus norvegicus,Ubiquinol-cytoch
CSB-EL007689HU Human ENTH domain-containing protein 1(ENTHD1) ELISA kit 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur