Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

AP2-like ethylene-responsive transcription factor ANT (Complementing a protein kinase C mutant protein 1) (Protein AINTEGUMENTA) (Protein DRAGON) (Protein OVULE MUTANT)

 ANT_ARATH               Reviewed;         555 AA.
Q38914; Q42462;
22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
22-NOV-2005, sequence version 2.
22-NOV-2017, entry version 119.
RecName: Full=AP2-like ethylene-responsive transcription factor ANT;
AltName: Full=Complementing a protein kinase C mutant protein 1;
AltName: Full=Protein AINTEGUMENTA;
AltName: Full=Protein DRAGON;
AltName: Full=Protein OVULE MUTANT;
Name=ANT; Synonyms=CKC1, DRG, OVM; OrderedLocusNames=At4g37750;
ORFNames=T28I19.30;
Arabidopsis thaliana (Mouse-ear cress).
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
Arabidopsis.
NCBI_TaxID=3702;
[1]
NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY, AND
MUTAGENESIS OF GLY-382.
STRAIN=cv. Landsberg erecta;
PubMed=8742706; DOI=10.1105/tpc.8.2.137;
Klucher K.M., Chow H., Reiser L., Fischer R.L.;
"The AINTEGUMENTA gene of Arabidopsis required for ovule and female
gametophyte development is related to the floral homeotic gene
APETALA2.";
Plant Cell 8:137-153(1996).
[2]
NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY, AND
DEVELOPMENTAL STAGE.
STRAIN=cv. Landsberg erecta; TISSUE=Flower;
PubMed=8742707; DOI=10.1105/tpc.8.2.155;
Elliott R.C., Betzner A.S., Huttner E., Oakes M.P., Tucker W.Q.J.,
Gerentes D., Perez P., Smyth D.R.;
"AINTEGUMENTA, an APETALA2-like gene of Arabidopsis with pleiotropic
roles in ovule development and floral organ growth.";
Plant Cell 8:155-168(1996).
[3]
NUCLEOTIDE SEQUENCE [MRNA], AND FUNCTION.
PubMed=9001406; DOI=10.1016/S0014-5793(96)01399-3;
Vergani P., Morandini P., Soave C.;
"Complementation of a yeast delta pkc1 mutant by the Arabidopsis
protein ANT.";
FEBS Lett. 400:243-246(1997).
[4]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=cv. Wassilewskija;
Fischer R.L., Mizukami Y.;
"Methods for altering mass and fertility in plants.";
Patent number US6559357, 06-MAY-2003.
[5]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
PubMed=10617198; DOI=10.1038/47134;
Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G.,
Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N.,
Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M.,
Weichselgartner M., de Simone V., Obermaier B., Mache R., Mueller M.,
Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T.,
Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I.,
Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P.,
Langham S.-A., McCullagh B., Bilham L., Robben J.,
van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F.,
Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E.,
Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W.,
Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P.,
Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H.,
De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R.,
van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S.,
Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R.,
Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S.,
Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H.,
Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S.,
Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A.,
Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R.,
Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S.,
Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E.,
Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A.,
Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T.,
Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C.,
Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S.,
Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K.,
Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L.,
Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J.,
Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J.,
Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D.,
Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D.,
Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C.,
Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C.,
Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R.,
Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S.,
Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A.,
Chen E., Marra M.A., Martienssen R., McCombie W.R.;
"Sequence and analysis of chromosome 4 of the plant Arabidopsis
thaliana.";
Nature 402:769-777(1999).
[6]
GENOME REANNOTATION.
STRAIN=cv. Columbia;
The Arabidopsis Information Portal (Araport);
Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
[7]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
PubMed=14593172; DOI=10.1126/science.1088305;
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J.,
Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F.,
Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.,
Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J.,
Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y.,
Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P.,
Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F.,
Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M.,
Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J.,
Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T.,
Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y.,
Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis
genome.";
Science 302:842-846(2003).
[8]
FUNCTION, AND REVIEW.
PubMed=12271029; DOI=10.1105/tpc.5.10.1291;
Reiser L., Fischer R.L.;
"The ovule and the embryo sac.";
Plant Cell 5:1291-1301(1993).
[9]
FUNCTION.
PubMed=9118807;
Schneitz K., Huelskamp M., Kopczak S.D., Pruitt R.E.;
"Dissection of sexual organ ontogenesis: a genetic analysis of ovule
development in Arabidopsis thaliana.";
Development 124:1367-1376(1997).
[10]
FUNCTION.
PubMed=9093862;
Baker S.C., Robinson-Beers K., Villanueva J.M., Gaiser J.C.,
Gasser C.S.;
"Interactions among genes regulating ovule development in Arabidopsis
thaliana.";
Genetics 145:1109-1124(1997).
[11]
DEVELOPMENTAL STAGE.
PubMed=9671577;
Long J.A., Barton M.K.;
"The development of apical embryonic pattern in Arabidopsis.";
Development 125:3027-3035(1998).
[12]
FUNCTION, AND MUTAGENESIS OF ALA-422.
PubMed=10528263;
DOI=10.1002/(SICI)1520-6408(1999)25:3<224::AID-DVG5>3.0.CO;2-Y;
Krizek B.A.;
"Ectopic expression of AINTEGUMENTA in Arabidopsis plants results in
increased growth of floral organs.";
Dev. Genet. 25:224-236(1999).
[13]
DEVELOPMENTAL STAGE.
PubMed=10656774; DOI=10.1006/dbio.1999.9572;
Long J., Barton M.K.;
"Initiation of axillary and floral meristems in Arabidopsis.";
Dev. Biol. 218:341-353(2000).
[14]
DNA-BINDING.
PubMed=11058102; DOI=10.1093/nar/28.21.4076;
Nole-Wilson S., Krizek B.A.;
"DNA binding properties of the Arabidopsis floral development protein
AINTEGUMENTA.";
Nucleic Acids Res. 28:4076-4082(2000).
[15]
FUNCTION.
PubMed=10948255; DOI=10.1105/tpc.12.8.1357;
Krizek B.A., Prost V., Macias A.;
"AINTEGUMENTA promotes petal identity and acts as a negative regulator
of AGAMOUS.";
Plant Cell 12:1357-1366(2000).
[16]
FUNCTION.
PubMed=11041883; DOI=10.1105/tpc.12.10.1879;
Liu Z., Franks R.G., Klink V.P.;
"Regulation of gynoecium marginal tissue formation by LEUNIG and
AINTEGUMENTA.";
Plant Cell 12:1879-1891(2000).
[17]
FUNCTION.
PubMed=10639184; DOI=10.1073/pnas.97.2.942;
Mizukami Y., Fischer R.L.;
"Plant organ size control: AINTEGUMENTA regulates growth and cell
numbers during organogenesis.";
Proc. Natl. Acad. Sci. U.S.A. 97:942-947(2000).
[18]
FUNCTION.
PubMed=12183381;
Balasubramanian S., Schneitz K.;
"NOZZLE links proximal-distal and adaxial-abaxial pattern formation
during ovule development in Arabidopsis thaliana.";
Development 129:4291-4300(2002).
[19]
FUNCTION, AND MUTAGENESIS OF ARG-285; VAL-287; THR-288; HIS-290;
TRP-301; ASN-303; GLY-314; VAL-317; TYR-318; LEU-319; TYR-322;
ASP-333; LEU-337; TYR-353; GLU-358; HIS-371; PHE-379; SER-380;
GLY-382; SER-384; TYR-386; ARG-387; VAL-389; HIS-392; HIS-393;
TYR-412; LEU-413; ALA-422; ALA-423; ASP-427; ILE-431; ILE-452;
281-THR--ILE-357; 383-ALA--ARG-451 AND 452-ILE--SER-555.
PubMed=12655002; DOI=10.1093/nar/gkg292;
Krizek B.A.;
"AINTEGUMENTA utilizes a mode of DNA recognition distinct from that
used by proteins containing a single AP2 domain.";
Nucleic Acids Res. 31:1859-1868(2003).
[20]
TISSUE SPECIFICITY.
PubMed=15988559; DOI=10.1007/s11103-005-0955-6;
Nole-Wilson S., Tranby T.L., Krizek B.A.;
"AINTEGUMENTA-like (AIL) genes are expressed in young tissues and may
specify meristematic or division-competent states.";
Plant Mol. Biol. 57:613-628(2005).
[21]
GENE FAMILY, AND NOMENCLATURE.
PubMed=16407444; DOI=10.1104/pp.105.073783;
Nakano T., Suzuki K., Fujimura T., Shinshi H.;
"Genome-wide analysis of the ERF gene family in Arabidopsis and
rice.";
Plant Physiol. 140:411-432(2006).
-!- FUNCTION: Transcription activator that recognizes and binds to the
DNA consensus sequence 5'-CAC[AG]N[AT]TNCCNANG-3'. Required for
the initiation and growth of ovules integumenta, and for the
development of female gametophyte. Plays a critical role in the
development of gynoecium marginal tissues (e.g. stigma, style and
septa), and in the fusion of carpels and of medial ridges leading
to ovule primordia. Also involved in organs initiation and
development, including floral organs. Maintains the meristematic
competence of cells and consequently sustains expression of cell
cycle regulators during organogenesis, thus controlling the final
size of each organ by controlling their cell number. Regulates INO
autoinduction and expression pattern. As ANT promotes petal cell
identity and mediates down-regulation of AG in flower whorl 2, it
functions as a class A homeotic gene.
{ECO:0000269|PubMed:10528263, ECO:0000269|PubMed:10639184,
ECO:0000269|PubMed:10948255, ECO:0000269|PubMed:11041883,
ECO:0000269|PubMed:12183381, ECO:0000269|PubMed:12271029,
ECO:0000269|PubMed:12655002, ECO:0000269|PubMed:8742706,
ECO:0000269|PubMed:8742707, ECO:0000269|PubMed:9001406,
ECO:0000269|PubMed:9093862, ECO:0000269|PubMed:9118807}.
-!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
-!- TISSUE SPECIFICITY: Mostly expressed in developing flowers. Also
present in mature flowers, siliques and seedlings, but not in
mature roots, leaves and stems. Expressed in ovules and in
vegetative and floral primordia. {ECO:0000269|PubMed:15988559,
ECO:0000269|PubMed:8742706, ECO:0000269|PubMed:8742707}.
-!- DEVELOPMENTAL STAGE: Expressed in floral primordia, in STM-
negative region, then in sepal primordia. As sepal develops,
progressively confined to a basal core before disappearing.
Present in stamen primordia, then confined to a central region as
they become stalked and develop locules. Later reduced to
procambial cells as stamen mature. From petal primordia, expressed
on the lateral edges of developing petals and finally confined to
petal epidermis before disappearing. Present in carpel primordia,
then in inner side of carpels especially in the placenta. Strong
levels in ovules primordia and young ovules, then localized in
integuments initiation zone before being confined to inner
integument cells that will differentiate into the endothelium.
Expressed in the distal half of the funiculus throughout ovule
development and later extends into the chalaza. After
fertilization, expression shift to the embryo. First on the apical
part at the globular stage, then in cotyledons primordia, and
later in cotyledons during the torpedo stage. As cotyledons grow
out, expression becomes limited to a plane separating adaxial and
abaxial parts. Excluded from the embryonic central region (ECR).
In seedlings, found in leaf primordia then in central and lateral
actively developing regions of extending leaves.
{ECO:0000269|PubMed:10656774, ECO:0000269|PubMed:8742707,
ECO:0000269|PubMed:9671577}.
-!- SIMILARITY: Belongs to the AP2/ERF transcription factor family.
AP2 subfamily. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; U40256; AAA91040.1; -; mRNA.
EMBL; U41339; AAB17364.1; -; mRNA.
EMBL; U44028; AAA86281.1; -; mRNA.
EMBL; AR316367; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AL035709; CAB38923.1; -; Genomic_DNA.
EMBL; AL161592; CAB80440.1; -; Genomic_DNA.
EMBL; CP002687; AEE86834.1; -; Genomic_DNA.
EMBL; AY080706; AAL85024.1; -; mRNA.
EMBL; AY117207; AAM51282.1; -; mRNA.
PIR; S71365; S71365.
RefSeq; NP_195489.1; NM_119937.3.
UniGene; At.1556; -.
ProteinModelPortal; Q38914; -.
SMR; Q38914; -.
STRING; 3702.AT4G37750.1; -.
PaxDb; Q38914; -.
EnsemblPlants; AT4G37750.1; AT4G37750.1; AT4G37750.
GeneID; 829931; -.
Gramene; AT4G37750.1; AT4G37750.1; AT4G37750.
KEGG; ath:AT4G37750; -.
Araport; AT4G37750; -.
TAIR; locus:2137559; AT4G37750.
eggNOG; ENOG410IEVJ; Eukaryota.
eggNOG; ENOG410Y9X6; LUCA.
HOGENOM; HOG000239258; -.
InParanoid; Q38914; -.
KO; K09285; -.
OMA; MTNSNNG; -.
OrthoDB; EOG09360BG2; -.
PhylomeDB; Q38914; -.
PRO; PR:Q38914; -.
Proteomes; UP000006548; Chromosome 4.
Genevisible; Q38914; AT.
GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO; GO:0003677; F:DNA binding; IDA:TAIR.
GO; GO:0043565; F:sequence-specific DNA binding; IPI:TAIR.
GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; ISS:TAIR.
GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
GO; GO:0009908; P:flower development; IEA:UniProtKB-KW.
GO; GO:0019760; P:glucosinolate metabolic process; IMP:TAIR.
GO; GO:0010492; P:maintenance of shoot apical meristem identity; IGI:TAIR.
GO; GO:0042127; P:regulation of cell proliferation; IMP:TAIR.
GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
CDD; cd00018; AP2; 2.
Gene3D; 3.30.730.10; -; 2.
InterPro; IPR031112; AP2-like_transcript_factor.
InterPro; IPR001471; AP2/ERF_dom.
InterPro; IPR036955; AP2/ERF_dom_sf.
InterPro; IPR016177; DNA-bd_dom_sf.
PANTHER; PTHR32467; PTHR32467; 1.
Pfam; PF00847; AP2; 2.
PRINTS; PR00367; ETHRSPELEMNT.
SMART; SM00380; AP2; 2.
SUPFAM; SSF54171; SSF54171; 2.
PROSITE; PS51032; AP2_ERF; 2.
1: Evidence at protein level;
Activator; Complete proteome; Developmental protein; Differentiation;
DNA-binding; Flowering; Nucleus; Reference proteome; Repeat;
Transcription; Transcription regulation.
CHAIN 1 555 AP2-like ethylene-responsive
transcription factor ANT.
/FTId=PRO_0000112524.
DNA_BIND 283 349 AP2/ERF 1. {ECO:0000255|PROSITE-
ProRule:PRU00366}.
DNA_BIND 385 443 AP2/ERF 2. {ECO:0000255|PROSITE-
ProRule:PRU00366}.
COMPBIAS 41 53 Ser-rich.
COMPBIAS 217 231 Gln-rich.
MUTAGEN 281 357 Missing: Loss of activation of
transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 285 285 R->G: Reduced activation of
transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 287 287 V->A: Loss of activation of
transcription; when associated with D-
303. {ECO:0000269|PubMed:12655002}.
MUTAGEN 287 287 V->D: Loss of activation of
transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 288 288 T->A: Reduced activation of
transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 290 290 H->A: Reduced activation of
transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 301 301 W->R: Reduced DNA-binding and loss of
activation of transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 303 303 N->D: Loss of activation of
transcription; when associated with A-
287. {ECO:0000269|PubMed:12655002}.
MUTAGEN 314 314 G->R: Loss of activation of
transcription; when associated with C-
353. {ECO:0000269|PubMed:12655002}.
MUTAGEN 317 317 V->D: No effect on DNA-binding but
reduced activation of transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 318 318 Y->C: Reduced DNA-binding and loss of
activation of transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 319 319 L->P: Loss of activation of
transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 319 319 L->Q: Reduced DNA-binding and loss of
activation of transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 322 322 Y->F: Loss of activation of
transcription; when associated with D-
386. {ECO:0000269|PubMed:12655002}.
MUTAGEN 333 333 D->E: Loss of activation of
transcription; when associated with T-
452. {ECO:0000269|PubMed:12655002}.
MUTAGEN 333 333 D->G: Reduced DNA-binding and loss of
activation of transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 337 337 L->P: Reduced DNA-binding and loss of
activation of transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 353 353 Y->C: Loss of activation of
transcription; when associated with R-
314. {ECO:0000269|PubMed:12655002}.
MUTAGEN 358 358 E->G: Loss of activation of
transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 371 371 H->P: Loss of activation of
transcription; when associated with A-
389. {ECO:0000269|PubMed:12655002}.
MUTAGEN 379 379 F->S: Loss of activation of
transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 380 380 S->P: Reduced DNA-binding and reduced
activation of transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 382 382 G->D: In ant-2; female-sterile, loss of
ovule integuments initiation, impaired
female gametophyte development, abnormal
floral organs, and loss of activation of
transcription.
{ECO:0000269|PubMed:12655002,
ECO:0000269|PubMed:8742706}.
MUTAGEN 383 451 Missing: Loss of activation of
transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 384 384 S->P: Loss of activation of
transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 386 386 Y->D: Loss of activation of
transcription; when associated with F-
322. {ECO:0000269|PubMed:12655002}.
MUTAGEN 387 387 R->G: Reduced DNA-binding and loss of
activation of transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 389 389 V->A: Loss of activation of
transcription; when associated with P-
371. {ECO:0000269|PubMed:12655002}.
MUTAGEN 389 389 V->D: Reduced activation of
transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 392 392 H->A: Reduced activation of
transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 393 393 H->A: Reduced activation of
transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 412 412 Y->C: Reduced activation of
transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 413 413 L->Q: Reduced activation of
transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 422 422 A->T: In ant-8; abnormal floral organs
and ovule development.
{ECO:0000269|PubMed:10528263,
ECO:0000269|PubMed:12655002}.
MUTAGEN 423 423 A->T: Reduced DNA-binding and loss of
activation of transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 427 427 D->G: Reduced DNA-binding and loss of
activation of transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 431 431 I->S: Reduced DNA-binding and reduced
activation of transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 452 555 Missing: No effect on activation of
transcription.
{ECO:0000269|PubMed:12655002}.
MUTAGEN 452 452 I->T: Loss of activation of
transcription; when associated with E-
333. {ECO:0000269|PubMed:12655002}.
CONFLICT 45 45 S -> C (in Ref. 3; AAA86281).
{ECO:0000305}.
SEQUENCE 555 AA; 61725 MW; BD275D2F082B519B CRC64;
MKSFCDNDDN NHSNTTNLLG FSLSSNMMKM GGRGGREAIY SSSTSSAATS SSSVPPQLVV
GDNTSNFGVC YGSNPNGGIY SHMSVMPLRS DGSLCLMEAL NRSSHSNHHQ DSSPKVEDFF
GTHHNNTSHK EAMDLSLDSL FYNTTHEPNT TTNFQEFFSF PQTRNHEEET RNYGNDPSLT
HGGSFNVGVY GEFQQSLSLS MSPGSQSSCI TGSHHHQQNQ NQNHQSQNHQ QISEALVETS
VGFETTTMAA AKKKRGQEDV VVVGQKQIVH RKSIDTFGQR TSQYRGVTRH RWTGRYEAHL
WDNSFKKEGH SRKGRQVYLG GYDMEEKAAR AYDLAALKYW GPSTHTNFSA ENYQKEIEDM
KNMTRQEYVA HLRRKSSGFS RGASIYRGVT RHHQHGRWQA RIGRVAGNKD LYLGTFGTQE
EAAEAYDVAA IKFRGTNAVT NFDITRYDVD RIMSSNTLLS GELARRNNNS IVVRNTEDQT
ALNAVVEGGS NKEVSTPERL LSFPAIFALP QVNQKMFGSN MGGNMSPWTS NPNAELKTVA
LTLPQMPVFA AWADS


Related products :

Catalog number Product name Quantity
orb81252 Human p53 Mutant protein p53 Mutant Human Recombinant full length protein (a.a 135) expressed in E.coli, shows 81 kDa band on SDS-PAGE.The p53 Mutant is purified by proprietary chromatographic techniq 2
orb80846 Human Phosphoinositide 3-kinase p110g inactive mutant protein The PI3KdD946A protein is catalytically inactive mutant of PI3Kd with D946A mutation in the ATP binding site. This recombinant catalytical 1
EIAAB09243 cAMP-responsive element-binding protein 3-like protein 3,CREB3L3,CREBH,Cyclic AMP-responsive element-binding protein 3-like protein 3,Homo sapiens,Human,HYST1481,Transcription factor CREB-H
EIAAB09244 cAMP-responsive element-binding protein 3-like protein 3,Creb3l3,Crebh,Cyclic AMP-responsive element-binding protein 3-like protein 3,Mouse,Mus musculus,Transcription factor CREB-H
EIAAB09242 cAMP-responsive element-binding protein 3-like protein 3,Creb3l3,Cyclic AMP-responsive element-binding protein 3-like protein 3,Rat,Rattus norvegicus,Transcription factor CREB-H
18-003-43089 Oligodendrocyte transcription factor 2 - Oligo2; Basic helix-loop-helix protein class B 1; Protein kinase C-binding protein RACK17; Protein kinase C-binding protein 2 Polyclonal 0.05 mg Aff Pur
EIAAB32247 ADP-ribosylation factor-like protein 6-interacting protein 5,Aip-5,ARL-6-interacting protein 5,ARL6IP5,Cytoskeleton-related vitamin A-responsive protein,Dermal papilla-derived protein 11,DERP11,Glutam
EIAAB41697 Homo sapiens,Human,KIAA0292,Nuclear factor SPBP,Protein AR1,SPBP,SPRE-binding protein,Stromelysin-1 PDGF-responsive element-binding protein,TCF20,TCF-20,Transcription factor 20
EIAAB47842 Ccdc16,Coiled-coil domain-containing protein 16,Mouse,Mus musculus,Omcg1,Ovus mutant candidate gene 1 protein,Zfp830,Zinc finger protein 830,Znf830
LEP26-QM-20 Ovine Recombinant Purified Leptin Quadruple mutant mutant Antagonist Protein 20 ug
LEP26-QM-100 Ovine Recombinant Purified Leptin Quadruple mutant mutant Antagonist Protein 100 ug
18-003-43828 Cyclic AMP-responsive element-binding protein 3 - Luman protein; Transcription factor LZIP-alpha Polyclonal 0.05 mg Aff Pur
18-003-42165 Early growth response protein 1 - EGR-1; Krox-24 protein; Transcription factor Zif268; Nerve growth factor-induced protein A; NGFI-A; Transcription factor ETR103; Zinc finger protein 225; AT225 Polycl 0.05 mg Aff Pur
18-003-42110 General transcription factor II-I - GTFII-I; TFII-I; Bruton tyrosine kinase-associated protein 135; BTK-associated protein 135; BAP-135; SRF-Phox1-interacting protein; SPIN; Williams-Beuren syndrome c 0.05 mg Aff Pur
18-003-42110 General transcription factor II-I - GTFII-I; TFII-I; Bruton tyrosine kinase-associated protein 135; BTK-associated protein 135; BAP-135; SRF-Phox1-interacting protein; SPIN; Williams-Beuren syndrome c 0.1 mg Protein A
27-699 CREB3 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts 0.05 mg
28-016 ATF2 encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein 0.1 mg
EIAAB09320 cAMP-responsive element-binding protein 3,CREB3,CREB-3,Cyclic AMP-responsive element-binding protein 3,Homo sapiens,Human,Luman,LZIP,Transcription factor LZIP-alpha
EIAAB09319 cAMP-responsive element-binding protein 3,Creb3,CREB-3,Cyclic AMP-responsive element-binding protein 3,Lzip,Mouse,Mus musculus,Transcription factor LZIP
18-003-42425 Mortality factor 4-like protein 2 - MORF-related gene X protein; Transcription factor-like protein MRGX; MSL3-2 protein Polyclonal 0.1 mg Protein A
18-003-42297 Mortality factor 4-like protein 1 - MORF-related gene 15 protein; Transcription factor-like protein MRG15; MSL3-1 protein Polyclonal 0.1 mg Protein A
EIAAB31334 Bos taurus,Bovine,PKN,PKN1,PRK1,PRKCL1,Protein kinase C-like 1,Protein kinase C-like PKN,Protein kinase PKN-alpha,Protein-kinase C-related kinase 1,Serine_threonine-protein kinase N1,Serine-threonine
18-003-42889 Cell division protein kinase 7 - EC 2.7.11.22; EC 2.7.11.23; CDK-activating kinase; CAK; TFIIH basal transcription factor complex kinase subunit; 39 kDa protein kinase; P39 Mo15; STK1; CAK1 Polyclonal 0.1 mg Protein A
EIAAB09247 AIbZIP,Aibzip,Androgen-induced basic leucine zipper protein,cAMP-responsive element-binding protein 3-like protein 4,Creb3l4,Cyclic AMP-responsive element-binding protein 3-like protein 4,Rat,Rattus n
EIAAB31332 Mouse,Mus musculus,Pkn,Pkn1,Prk1,Prkcl1,Protein kinase C-like 1,Protein kinase C-like PKN,Protein-kinase C-related kinase 1,Serine_threonine-protein kinase N1,Serine-threonine protein kinase N


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur