Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

ATP-dependent zinc metalloprotease FtsH (EC 3.4.24.-)

 R5LKE6_9MOLU            Unreviewed;       655 AA.
R5LKE6;
24-JUL-2013, integrated into UniProtKB/TrEMBL.
24-JUL-2013, sequence version 1.
27-SEP-2017, entry version 21.
RecName: Full=ATP-dependent zinc metalloprotease FtsH {ECO:0000256|HAMAP-Rule:MF_01458};
EC=3.4.24.- {ECO:0000256|HAMAP-Rule:MF_01458};
Name=ftsH {ECO:0000256|HAMAP-Rule:MF_01458};
ORFNames=BN801_00924 {ECO:0000313|EMBL:CCY79645.1};
Mycoplasma sp. CAG:877.
Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma;
environmental samples.
NCBI_TaxID=1262907 {ECO:0000313|EMBL:CCY79645.1, ECO:0000313|Proteomes:UP000018280};
[1] {ECO:0000313|EMBL:CCY79645.1, ECO:0000313|Proteomes:UP000018280}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=MGS:877 {ECO:0000313|Proteomes:UP000018280};
Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J.,
Sunagawa S., Plichta D., Gautier L., Le Chatelier E., Peletier E.,
Bonde I., Nielsen T., Manichanh C., Arumugam M., Batto J.,
Santos M.B.Q.D., Blom N., Borruel N., Burgdorf K.S., Boumezbeur F.,
Casellas F., Dore J., Guarner F., Hansen T., Hildebrand F., Kaas R.S.,
Kennedy S., Kristiansen K., Kultima J.R., Leonard P., Levenez F.,
Lund O., Moumen B., Le Paslier D., Pons N., Pedersen O., Prifti E.,
Qin J., Raes J., Tap J., Tims S., Ussery D.W., Yamada T.,
MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P., Wang J.,
Brunak S., Ehrlich S.D.;
"Dependencies among metagenomic species, viruses, plasmids and units
of genetic variation.";
Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
-!- FUNCTION: Acts as a processive, ATP-dependent zinc
metallopeptidase for both cytoplasmic and membrane proteins. Plays
a role in the quality control of integral membrane proteins.
{ECO:0000256|HAMAP-Rule:MF_01458}.
-!- COFACTOR:
Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
Evidence={ECO:0000256|HAMAP-Rule:MF_01458};
Note=Binds 1 zinc ion per subunit. {ECO:0000256|HAMAP-
Rule:MF_01458};
-!- SUBUNIT: Homohexamer. {ECO:0000256|HAMAP-Rule:MF_01458}.
-!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-
Rule:MF_01458}; Multi-pass membrane protein {ECO:0000256|HAMAP-
Rule:MF_01458}; Cytoplasmic side {ECO:0000256|HAMAP-
Rule:MF_01458}.
-!- SIMILARITY: Belongs to the AAA ATPase family.
{ECO:0000256|RuleBase:RU003651}.
-!- SIMILARITY: In the C-terminal section; belongs to the peptidase
M41 family. {ECO:0000256|HAMAP-Rule:MF_01458}.
-!- SIMILARITY: In the central section; belongs to the AAA ATPase
family. {ECO:0000256|HAMAP-Rule:MF_01458}.
-!- CAUTION: The sequence shown here is derived from an
EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
preliminary data. {ECO:0000313|EMBL:CCY79645.1}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; CAYV010000043; CCY79645.1; -; Genomic_DNA.
Proteomes; UP000018280; Unassembled WGS sequence.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
GO; GO:0016887; F:ATPase activity; IEA:UniProtKB-UniRule.
GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
GO; GO:0006353; P:DNA-templated transcription, termination; IEA:InterPro.
GO; GO:0030163; P:protein catabolic process; IEA:UniProtKB-UniRule.
HAMAP; MF_01458; FtsH; 1.
InterPro; IPR003593; AAA+_ATPase.
InterPro; IPR003959; ATPase_AAA_core.
InterPro; IPR003960; ATPase_AAA_CS.
InterPro; IPR005936; FtsH.
InterPro; IPR027417; P-loop_NTPase.
InterPro; IPR011546; Pept_M41_FtsH_extracell.
InterPro; IPR000642; Peptidase_M41.
InterPro; IPR011112; Rho_N.
Pfam; PF00004; AAA; 1.
Pfam; PF06480; FtsH_ext; 1.
Pfam; PF01434; Peptidase_M41; 1.
Pfam; PF07498; Rho_N; 1.
SMART; SM00382; AAA; 1.
SUPFAM; SSF52540; SSF52540; 1.
TIGRFAMs; TIGR01241; FtsH_fam; 1.
PROSITE; PS00674; AAA; 1.
3: Inferred from homology;
ATP-binding {ECO:0000256|HAMAP-Rule:MF_01458,
ECO:0000256|RuleBase:RU003651};
Cell membrane {ECO:0000256|HAMAP-Rule:MF_01458};
Complete proteome {ECO:0000313|Proteomes:UP000018280};
Hydrolase {ECO:0000256|HAMAP-Rule:MF_01458,
ECO:0000313|EMBL:CCY79645.1};
Membrane {ECO:0000256|HAMAP-Rule:MF_01458};
Metal-binding {ECO:0000256|HAMAP-Rule:MF_01458};
Metalloprotease {ECO:0000256|HAMAP-Rule:MF_01458,
ECO:0000313|EMBL:CCY79645.1};
Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01458,
ECO:0000256|RuleBase:RU003651};
Protease {ECO:0000256|HAMAP-Rule:MF_01458,
ECO:0000313|EMBL:CCY79645.1};
Reference proteome {ECO:0000313|Proteomes:UP000018280};
Transmembrane {ECO:0000256|HAMAP-Rule:MF_01458};
Transmembrane helix {ECO:0000256|HAMAP-Rule:MF_01458};
Zinc {ECO:0000256|HAMAP-Rule:MF_01458}.
TRANSMEM 12 32 Helical. {ECO:0000256|HAMAP-
Rule:MF_01458}.
TRANSMEM 118 139 Helical. {ECO:0000256|HAMAP-
Rule:MF_01458}.
DOMAIN 201 340 AAA. {ECO:0000259|SMART:SM00382}.
NP_BIND 209 216 ATP. {ECO:0000256|HAMAP-Rule:MF_01458}.
ACT_SITE 432 432 {ECO:0000256|HAMAP-Rule:MF_01458}.
METAL 431 431 Zinc; catalytic. {ECO:0000256|HAMAP-
Rule:MF_01458}.
METAL 435 435 Zinc; catalytic. {ECO:0000256|HAMAP-
Rule:MF_01458}.
METAL 507 507 Zinc; catalytic. {ECO:0000256|HAMAP-
Rule:MF_01458}.
SEQUENCE 655 AA; 72741 MW; 91D3708C691F7202 CRC64;
MNIDKKTVKR GLLPYLFLFI AMLGIFYFFN IANKKVNVIS YNEFVEKLDS GEIEELNLVA
RASGYTYEAR GKLDGYKENE TFFARLPLSD EVMKKIVAAS DNQEFKLEVE PDPDSSTLLL
VVVNVLPLVL LVGVAFWFLN RQLAGNKSSL DFGKSKARLS SDNNKVTFKD VAGLKEEKEE
VKEIIDFLKN PKKFQSLGAR IPKGILLFGP PGTGKTLLAK AVAGEANVPF YFISGSDFVE
LFVGVGASRV RDMFQQAKRN APCLIFIDEI DAVGRQRGTG LGGGHDEREQ TLNQLLTEMD
GFGANEGIII MAATNRPDVL DPALLRPGRF DRQVTVNLPD VREREEILAV HAKNKTLAEG
VTLENLAKRT PGFSGADLEN LLNEAALLAV RRNKTKITMS EIDEATDRVL MGPAKTSHKY
SESDRKLVAY HEAGHAVVGL KLANANDVQK VTIIPRGSAG GYNMMVPSVE KLCSTKTDLL
EEITGLLGGR TAEEVVFGEI TTGAHNDFEK ATKIARAMVT EYGMSDLGPL QFEQQEGSVF
LGRDYNKMQH FSNEVANEID MEMRKIIDNC HKKATEIIKQ NKDLLKLIAE ALLEYETLTK
EQIDYLVANG KMPEEDEETS YEAMSITKLR EIAKEKGIKN YSKLTKAELL KELDS


Related products :

Catalog number Product name Quantity
EIAAB46691 ATP-dependent metalloprotease FtsH1,ATP-dependent zinc metalloprotease YME1L1,FTSH1,Homo sapiens,Human,Meg-4,PAMP,Presenilin-associated metalloprotease,UNQ1868_PRO4304,YME1L,YME1L1,YME1-like protein 1
EIAAB46692 ATP-dependent metalloprotease FtsH1,ATP-dependent zinc metalloprotease YME1L1,Mouse,Mus musculus,Yme1l1,YME1-like protein 1
EIAAB46693 ATP-dependent metalloprotease FtsH1,ATP-dependent zinc metalloprotease YME1L1,Meg-4,Rat,Rattus norvegicus,Yme1l1,YME1-like protein 1
AS11 1789 Antibody: FtsH1, 3,5,10 | plant ftsh metallo-protease H1+H3 + H5+ H10, Immunogen: KLH-conjugated peptide dereived from sequences of all known FtsH isoforms of Arabidopsis thaliana including FtsH3 and 500
CSB-EL026267MO Mouse ATP-dependent zinc metalloprotease YME1L1(YME1L1) ELISA kit SpeciesMouse 96T
CSB-EL026267HU Human ATP-dependent zinc metalloprotease YME1L1(YME1L1) ELISA kit SpeciesHuman 96T
CSB-EL026267HU Human ATP-dependent zinc metalloprotease YME1L1(YME1L1) ELISA kit 96T
CSB-EL026267MO Mouse ATP-dependent zinc metalloprotease YME1L1(YME1L1) ELISA kit 96T
CSB-EL026267RA Rat ATP-dependent zinc metalloprotease YME1L1(YME1L1) ELISA kit SpeciesRat 96T
CSB-EL026267RA Rat ATP-dependent zinc metalloprotease YME1L1(YME1L1) ELISA kit 96T
AS101592 sll0528 putative zinc metalloprotease sII0528 100 µl
AS08356 FtsH2 | plant ftsh metallo_protease H2
AS10 1623 rabbit polyclonal sll0528 | putative zinc metalloprotease sII0528 300 ul
AS10 1592 rabbit polyclonal sll0528 | putative zinc metalloprotease sII0528 100 ul
AS11 1789 rabbit polyclonal FtsH1,2,3,4,5,6,7,8,9,10,11 | ftsh metallo-protease H1+H2+H3+H4+H5+H6+H7+H8+H9+H10+H11 500
Zmpste24-101AP Zinc Metalloprotease Ste24 homolog Polyclonal anbtibody Host: Rabbit Affinity purifed 200ul
Zmpste24-101AP Zinc Metalloprotease Ste24 homolog WB control: PC-Zmpt24 Host: Rabbit Affinity purifed 100-150ul
Zmpste24-112AP Zinc Metalloprotease Ste24 homolog Antigenic peptide: P-Zmpt24-2 Host: Rabbit Affinity purifed 100ul
Zmpste24-101AP Zinc Metalloprotease Ste24 homolog Antigenic peptide: P-Zmpt24-1 Host: Rabbit Affinity purifed 100ul
AS10 1621 rabbit polyclonal slr1821 | putative zinc metalloprotease slr1821 300 ul
AS10 1596 rabbit polyclonal slr1821 | putative zinc metalloprotease slr1821 100 ul
AS08 356 Antibody: FtsH2 | plant ftsh metallo-protease H2, Host: rabbit, polyclonal, Confirmed reactivity: Arabidopsis thaliana
AS101596 slr1821 | putative zinc metalloprotease slr1821 100 µl
Zmpste24-112AP Zinc Metalloprotease Ste24 homolog Biotin Conjugates: Zmpt24-2-Biotin Host: Rabbit Affinity purifed 200ul
Zmpste24-101AP Zinc Metalloprotease Ste24 homolog FITC-conjugates: Zmpt24-1-FITC Host: Rabbit Affinity purifed 200ul


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur