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Agouti related protein (Fragment)

 Q9QXJ3_RAT              Unreviewed;        78 AA.
Q9QXJ3;
01-MAY-2000, integrated into UniProtKB/TrEMBL.
01-MAY-2000, sequence version 1.
23-MAY-2018, entry version 90.
SubName: Full=Agouti related protein {ECO:0000313|EMBL:AAF20203.1};
Flags: Fragment;
Name=AGRP {ECO:0000313|EMBL:AAF20203.1};
Rattus norvegicus (Rat).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Rattus.
NCBI_TaxID=10116 {ECO:0000313|EMBL:AAF20203.1};
[1] {ECO:0000313|EMBL:AAF20203.1}
NUCLEOTIDE SEQUENCE.
STRAIN=LA/N {ECO:0000313|EMBL:AAF20203.1};
TISSUE=Hypothalamus {ECO:0000313|EMBL:AAF20203.1};
PubMed=10875247; DOI=10.1210/en.141.7.2465;
Korner J., Wardlaw S.L., Liu S.M., Conwell I.M., Leibel R.L.,
Chua S.C. Jr;
"Effects of leptin receptor mutation on Agrp gene expression in fed
and fasted lean and obese (LA/N-faf) rats.";
Endocrinology 141:2465-2471(2000).
-!- CAUTION: Lacks conserved residue(s) required for the propagation
of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00494}.
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EMBL; AF206017; AAF20203.1; -; mRNA.
UniGene; Rn.137597; -.
ProteinModelPortal; Q9QXJ3; -.
UCSC; RGD:2068; rat.
eggNOG; ENOG410J14P; Eukaryota.
eggNOG; ENOG410Z66T; LUCA.
HOGENOM; HOG000033861; -.
PhylomeDB; Q9QXJ3; -.
GO; GO:0005576; C:extracellular region; IEA:InterPro.
GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
GO; GO:0009755; P:hormone-mediated signaling pathway; IEA:InterPro.
Gene3D; 4.10.760.10; -; 1.
InterPro; IPR007733; Agouti.
InterPro; IPR027300; Agouti_dom.
InterPro; IPR036836; Agouti_dom_sf.
PANTHER; PTHR16551; PTHR16551; 1.
Pfam; PF05039; Agouti; 1.
SMART; SM00792; Agouti; 1.
SUPFAM; SSF57055; SSF57055; 1.
PROSITE; PS51150; AGOUTI_2; 1.
2: Evidence at transcript level;
Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00494}.
DOMAIN 46 78 Agouti. {ECO:0000259|PROSITE:PS51150}.
DISULFID 46 61 {ECO:0000256|PROSITE-ProRule:PRU00494}.
DISULFID 53 67 {ECO:0000256|PROSITE-ProRule:PRU00494}.
NON_TER 1 1 {ECO:0000313|EMBL:AAF20203.1}.
NON_TER 78 78 {ECO:0000313|EMBL:AAF20203.1}.
SEQUENCE 78 AA; 8889 MW; DF9A7131E0C11DF7 CRC64;
LFPEFSGLSL KKTAADRAED VLLQKAEALA EVLDPQNRES RSPRRCVRLH ESCLGQQVPC
CDLCATCYCR FFKTCYCR


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