Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Allergin-1 (Allergy inhibitory receptor 1) (Mast cell antigen 32) (MCA-32) (Mast cell Ag-32) (Mast cell immunoglobulin-like receptor 1)

 MILR1_RAT               Reviewed;         248 AA.
Q62875;
23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
23-OCT-2007, sequence version 2.
23-MAY-2018, entry version 83.
RecName: Full=Allergin-1;
AltName: Full=Allergy inhibitory receptor 1;
AltName: Full=Mast cell antigen 32;
Short=MCA-32;
Short=Mast cell Ag-32;
AltName: Full=Mast cell immunoglobulin-like receptor 1;
Flags: Precursor;
Name=Milr1; Synonyms=Mca32;
Rattus norvegicus (Rat).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Rattus.
NCBI_TaxID=10116;
[1]
NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, INDUCTION, AND
TISSUE SPECIFICITY.
PubMed=7499870;
Pirozzi G., Terry R.W., Epstein D., Labow M.A.;
"Identification and characterization of a novel surface antigen gene
induced in mast cells activated through the high affinity IgE
receptor.";
J. Immunol. 155:5811-5818(1995).
-!- FUNCTION: Immunoglobulin-like receptor which plays an inhibitory
role in degranulation of mast cells. Negatively regulates IgE-
mediated mast cell activation and suppresses the type I immediate
hypersensitivity reaction (By similarity). {ECO:0000250}.
-!- SUBUNIT: Monomer. Interacts (tyrosine-phosphorylated) with PTPN6,
PTPN11 and INPP5D. {ECO:0000250}.
-!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:7499870};
Single-pass type I membrane protein {ECO:0000269|PubMed:7499870}.
-!- TISSUE SPECIFICITY: Mast cell-specific. Expressed in primary and
transformed mast cells. {ECO:0000269|PubMed:7499870}.
-!- INDUCTION: Up-regulated in response to mast cell activation.
{ECO:0000269|PubMed:7499870}.
-!- PTM: N-glycosylated. {ECO:0000250}.
-!- SEQUENCE CAUTION:
Sequence=AAC52339.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; U39546; AAC52339.1; ALT_INIT; mRNA.
RefSeq; NP_067596.1; NM_021585.1.
UniGene; Rn.40569; -.
ProteinModelPortal; Q62875; -.
SMR; Q62875; -.
iPTMnet; Q62875; -.
PhosphoSitePlus; Q62875; -.
PaxDb; Q62875; -.
PRIDE; Q62875; -.
GeneID; 59105; -.
KEGG; rno:59105; -.
UCSC; RGD:620488; rat.
CTD; 284021; -.
RGD; 620488; Milr1.
HOVERGEN; HBG108121; -.
InParanoid; Q62875; -.
PhylomeDB; Q62875; -.
PRO; PR:Q62875; -.
Proteomes; UP000002494; Unplaced.
GO; GO:0005887; C:integral component of plasma membrane; ISS:UniProtKB.
GO; GO:0042629; C:mast cell granule; IEA:GOC.
GO; GO:0043303; P:mast cell degranulation; ISS:UniProtKB.
GO; GO:0033004; P:negative regulation of mast cell activation; ISS:UniProtKB.
Gene3D; 2.60.40.10; -; 1.
InterPro; IPR029626; Allergin-1.
InterPro; IPR007110; Ig-like_dom.
InterPro; IPR036179; Ig-like_dom_sf.
InterPro; IPR013783; Ig-like_fold.
InterPro; IPR003599; Ig_sub.
PANTHER; PTHR11481:SF58; PTHR11481:SF58; 2.
Pfam; PF13895; Ig_2; 1.
SMART; SM00409; IG; 1.
SUPFAM; SSF48726; SSF48726; 1.
PROSITE; PS50835; IG_LIKE; 1.
2: Evidence at transcript level;
Cell membrane; Complete proteome; Disulfide bond; Glycoprotein;
Immunoglobulin domain; Membrane; Phosphoprotein; Reference proteome;
Signal; Transmembrane; Transmembrane helix.
SIGNAL 1 33 {ECO:0000255}.
CHAIN 34 248 Allergin-1.
/FTId=PRO_0000307366.
TOPO_DOM 34 150 Extracellular. {ECO:0000255}.
TRANSMEM 151 171 Helical. {ECO:0000255}.
TOPO_DOM 172 248 Cytoplasmic. {ECO:0000255}.
DOMAIN 54 137 Ig-like C2-type.
MOTIF 216 221 ITIM motif. {ECO:0000250}.
MOTIF 241 246 ITIM motif. {ECO:0000250}.
MOD_RES 218 218 Phosphotyrosine.
{ECO:0000250|UniProtKB:Q3TB92}.
MOD_RES 243 243 Phosphotyrosine.
{ECO:0000250|UniProtKB:Q3TB92}.
CARBOHYD 68 68 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 135 135 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
DISULFID 73 120 {ECO:0000255|PROSITE-ProRule:PRU00114}.
SEQUENCE 248 AA; 27459 MW; 47F1BC8906F51116 CRC64;
MGDDDTPVCL SVASCKGVSC WLDKLLLWAL TLSITLRNTA VDCRRVDRNG LLSPNLNSSM
SVVRMGQNVS LSCSSKNTSI DITYSLFLGK RYLESKRRRG GAVDFHLRIS NANESGPYKC
KVNDSNSSKY SQNFNFTIIQ DESCSSCLLS LLLPGVLLGL ILPGLAFLIY LKYKKGCTGK
TLKENESKGS GDAPTQGELY ANICETQKGS EQLQEIHYTT PVFKEVAPTE QEGLEDRKDD
YIYSELTY


Related products :

Catalog number Product name Quantity
EIAAB24768 Allergin-1,Allergy inhibitory receptor 1,Gm885,Mast cell Ag-32,Mast cell antigen 32,Mast cell immunoglobulin-like receptor 1,Mca32,MCA-32,Milr1,Mouse,Mus musculus
EIAAB24767 Allergin-1,Allergy inhibitory receptor 1,Mast cell Ag-32,Mast cell antigen 32,Mast cell immunoglobulin-like receptor 1,Mca32,MCA-32,Milr1,Rat,Rattus norvegicus
EIAAB24766 Allergin-1,Allergy inhibitory receptor 1,C17orf60,Homo sapiens,Human,Mast cell antigen 32,Mast cell immunoglobulin-like receptor 1,MCA32,MCA-32,MILR1
U2059m CLIA kit Alpha-chymase,Chymase,Cma1,Mast cell chymase 1,Mast cell protease 5,Mast cell protease I,Mcpt5,mMCP-5,Mouse,Mus musculus 96T
E2059m ELISA kit Alpha-chymase,Chymase,Cma1,Mast cell chymase 1,Mast cell protease 5,Mast cell protease I,Mcpt5,mMCP-5,Mouse,Mus musculus 96T
U2059m CLIA Alpha-chymase,Chymase,Cma1,Mast cell chymase 1,Mast cell protease 5,Mast cell protease I,Mcpt5,mMCP-5,Mouse,Mus musculus 96T
E2059m ELISA Alpha-chymase,Chymase,Cma1,Mast cell chymase 1,Mast cell protease 5,Mast cell protease I,Mcpt5,mMCP-5,Mouse,Mus musculus 96T
E2059r ELISA kit Alpha-chymase,Chymase,Cma1,Mast cell protease 3,Mast cell protease 5,Mast cell protease III,Mcpt3,Rat,Rattus norvegicus,rMCP-3,rMCP-5,rMCP-III 96T
E2059r ELISA Alpha-chymase,Chymase,Cma1,Mast cell protease 3,Mast cell protease 5,Mast cell protease III,Mcpt3,Rat,Rattus norvegicus,rMCP-3,rMCP-5,rMCP-III 96T
U2059r CLIA kit Alpha-chymase,Chymase,Cma1,Mast cell protease 3,Mast cell protease 5,Mast cell protease III,Mcpt3,Rat,Rattus norvegicus,rMCP-3,rMCP-5,rMCP-III 96T
U2059r CLIA Alpha-chymase,Chymase,Cma1,Mast cell protease 3,Mast cell protease 5,Mast cell protease III,Mcpt3,Rat,Rattus norvegicus,rMCP-3,rMCP-5,rMCP-III 96T
LF-MA41502 anti-Mast Cell Tryptase (3H2643), Mouse monoclonal to Mast Cell Tryptase, Isotype IgG1 50 ug
LF-MA41487 anti-Mast Cell Tryptase (AA1), Mouse monoclonal to Mast Cell Tryptase, Isotype IgG1 50 ug
EIAAB07943 CD300 antigen-like family member A,Cd300a,Clm8,CLM-8,CMRF35-like molecule 8,Leukocyte mono-Ig-like receptor 1,Lmir1,MAIR-1,MAIR-I,Mast cell-derived paired immunoglobulin-like receptor 1,Mcpir1,Mouse,M
MCA1438 MOUSE ANTI HUMAN MAST CELL TRYPTASE, Product Type Monoclonal Antibody, Specificity MAST CELL TRYPTASE, Target Species Human, Host Mouse, Format Purified, Isotypes IgG1, Applications C, E, P*, W 0.2 mg
SCH-MCA1930 MOUSE ANTI HUMAN MAST CELL CHYMASE, Product Type Monoclonal Antibody, Specificity MAST CELL CHYMASE, Target Species Human, Host Mouse, Format Purified, Isotypes IgG1, Applications E, P, WB, Clo 0.1 mg
SCH-MCA1438 MOUSE ANTI HUMAN MAST CELL TRYPTASE, Product Type Monoclonal Antibody, Specificity MAST CELL TRYPTASE, Target Species Human, Host Mouse, Format Purified, Isotypes IgG1, Applications C, E, P*, W 0.2 mg
MCA1930 MOUSE ANTI HUMAN MAST CELL CHYMASE, Product Type Monoclonal Antibody, Specificity MAST CELL CHYMASE, Target Species Human, Host Mouse, Format Purified, Isotypes IgG1, Applications E, P, WB, Clo 0.1 mg
MCA1930T MOUSE ANTI HUMAN MAST CELL CHYMASE, Product Type Monoclonal Antibody, Specificity MAST CELL CHYMASE, Target Species Human, Host Mouse, Format Purified, Isotypes IgG1, Applications P, Clone CC1 10 µg
MCA1438T MOUSE ANTI HUMAN MAST CELL TRYPTASE, Product Type Monoclonal Antibody, Specificity MAST CELL TRYPTASE, Target Species Human, Host Mouse, Format Purified, Isotypes IgG1, Applications C, P*, Clon 20 µg
SCH-MCA1930T MOUSE ANTI HUMAN MAST CELL CHYMASE, Product Type Monoclonal Antibody, Specificity MAST CELL CHYMASE, Target Species Human, Host Mouse, Format Purified, Isotypes IgG1, Applications P, Clone CC1 10 µg
SCH-MCA1438T MOUSE ANTI HUMAN MAST CELL TRYPTASE, Product Type Monoclonal Antibody, Specificity MAST CELL TRYPTASE, Target Species Human, Host Mouse, Format Purified, Isotypes IgG1, Applications C, P*, Clon 20 µg
CS-MAST Toluidine Blue (Mast Cell) Control Slides Paraffin Sections, 5 slides pack
X2189P Human Mast per stem cell growth factor receptor per SCRF per KIT Antigen Immunoaffinity Purified Polyclonal 50
X2188P Human Mast per stem cell growth factor receptor per SCRF per KIT Antigen Immunoaffinity Purified Polyclonal 50


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur