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Alpha-amylase/trypsin inhibitor CM2 (Chloroform/methanol-soluble protein CM2)

 IAAC2_WHEAT             Reviewed;         145 AA.
P16851;
01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
01-MAR-1992, sequence version 2.
10-MAY-2017, entry version 81.
RecName: Full=Alpha-amylase/trypsin inhibitor CM2;
AltName: Full=Chloroform/methanol-soluble protein CM2;
Flags: Precursor;
Triticum aestivum (Wheat).
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BOP clade;
Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
NCBI_TaxID=4565;
[1]
NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=cv. Agathe; TISSUE=Seed;
PubMed=1893104; DOI=10.1007/BF00020564;
Gautier M.-F., Alary R., Lullien V., Joudrier P.;
"Nucleotide sequence of a cDNA clone encoding the wheat (Triticum
durum Desf.) CM2 protein.";
Plant Mol. Biol. 16:333-334(1991).
[2]
PROTEIN SEQUENCE OF 26-53.
Barber D., Sanchez-Monge R., Garcia-Olmedo F., Salcedo G., Mendez E.;
"Evolutionary implications of sequential homologies among members of
the trypsin / alpha-amylase inhibitor family (CM-proteins) in wheat
and barley.";
Biochim. Biophys. Acta 873:147-151(1986).
-!- FUNCTION: Alpha-amylase/trypsin inhibitor. It could be involved in
insect defense mechanisms.
-!- SUBCELLULAR LOCATION: Secreted.
-!- TISSUE SPECIFICITY: Developing endosperm.
-!- MISCELLANEOUS: CM proteins would be involved in the cooking
quality of pasta.
-!- SIMILARITY: Belongs to the protease inhibitor I6 (cereal
trypsin/alpha-amylase inhibitor) family. {ECO:0000305}.
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EMBL; X55454; CAA39099.1; -; mRNA.
PIR; B25310; B25310.
ProteinModelPortal; P16851; -.
SMR; P16851; -.
Allergome; 8188; Tri a 29.
MEROPS; I06.004; -.
Proteomes; UP000019116; Unplaced.
GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO; GO:0015066; F:alpha-amylase inhibitor activity; IEA:UniProtKB-KW.
GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
InterPro; IPR006106; Allergen/soft/tryp_amyl_inhib.
InterPro; IPR006105; Allergen/tryp_amyl_inhib_CS.
InterPro; IPR016140; Bifunc_inhib/LTP/seed_store.
Pfam; PF00234; Tryp_alpha_amyl; 1.
PRINTS; PR00808; AMLASEINHBTR.
SMART; SM00499; AAI; 1.
SUPFAM; SSF47699; SSF47699; 1.
PROSITE; PS00426; CEREAL_TRYP_AMYL_INH; 1.
1: Evidence at protein level;
Alpha-amylase inhibitor; Complete proteome; Direct protein sequencing;
Protease inhibitor; Reference proteome; Secreted;
Serine protease inhibitor; Signal.
SIGNAL 1 25 {ECO:0000269|Ref.2}.
CHAIN 26 145 Alpha-amylase/trypsin inhibitor CM2.
/FTId=PRO_0000014345.
SEQUENCE 145 AA; 15460 MW; 8A6C95C1DF88940C CRC64;
MASKSSITHL LLAAVLVSVF AAAAATGPYC YPGMGLPSNP LEGCREYVAQ QTCGVGIVGS
PVSTEPGNTP RDRCCKELYD ASQHCRCEAV RYFIGRTSDP NSGVLKDLPG CPREPQRDFA
KVLVTPGHCN VMTVHNTPYC LGLDI


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