Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Alpha-barbatene synthase (AtBS) (EC 4.2.3.69) (Beta-chamigrene synthase) (EC 4.2.3.78) (Terpeneoid synthase 11) (AtTPS11) (Thujopsene synthase) (EC 4.2.3.79)

 BARS_ARATH              Reviewed;         557 AA.
Q4KSH9; A3KPF7; Q9LU03;
28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
28-JUL-2009, sequence version 2.
25-OCT-2017, entry version 80.
RecName: Full=Alpha-barbatene synthase;
Short=AtBS;
EC=4.2.3.69;
AltName: Full=Beta-chamigrene synthase;
EC=4.2.3.78;
AltName: Full=Terpeneoid synthase 11;
Short=AtTPS11;
AltName: Full=Thujopsene synthase;
EC=4.2.3.79;
Name=BS; Synonyms=TPS11; OrderedLocusNames=At5g44630;
ORFNames=K15C23.7;
Arabidopsis thaliana (Mouse-ear cress).
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
Arabidopsis.
NCBI_TaxID=3702;
[1]
NUCLEOTIDE SEQUENCE [MRNA], AND FUNCTION.
PubMed=15965019; DOI=10.1104/pp.105.059386;
Wu S., Schoenbeck M.A., Greenhagen B.T., Takahashi S., Lee S.,
Coates R.M., Chappell J.;
"Surrogate splicing for functional analysis of sesquiterpene synthase
genes.";
Plant Physiol. 138:1322-1333(2005).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H.,
Tabata S.;
"Structural analysis of Arabidopsis thaliana chromosome 5. XI.";
Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.
[3]
GENOME REANNOTATION.
STRAIN=cv. Columbia;
The Arabidopsis Information Portal (Araport);
Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
Bautista V.R., Kim C.J., Chen H., Wu S.Y., De Los Reyes C.,
Ecker J.R.;
"Arabidopsis ORF clones.";
Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
[5]
GENE FAMILY, AND NOMENCLATURE.
PubMed=12207221; DOI=10.1007/s00438-002-0709-y;
Aubourg S., Lecharny A., Bohlmann J.;
"Genomic analysis of the terpenoid synthase (AtTPS) gene family of
Arabidopsis thaliana.";
Mol. Genet. Genomics 267:730-745(2002).
[6]
TISSUE SPECIFICITY.
PubMed=12566586; DOI=10.1105/tpc.007989;
Chen F., Tholl D., D'Auria J.C., Farooq A., Pichersky E.,
Gershenzon J.;
"Biosynthesis and emission of terpenoid volatiles from Arabidopsis
flowers.";
Plant Cell 15:481-494(2003).
[7]
GENE FAMILY.
PubMed=12777052; DOI=10.1023/A:1023005504702;
Lange B.M., Ghassemian M.;
"Genome organization in Arabidopsis thaliana: a survey for genes
involved in isoprenoid and chlorophyll metabolism.";
Plant Mol. Biol. 51:925-948(2003).
[8]
FUNCTION, CATALYTIC ACTIVITY, BIOPHYSICOCHEMICAL PROPERTIES,
DISRUPTION PHENOTYPE, AND TISSUE SPECIFICITY.
PubMed=15918888; DOI=10.1111/j.1365-313X.2005.02417.x;
Tholl D., Chen F., Petri J., Gershenzon J., Pichersky E.;
"Two sesquiterpene synthases are responsible for the complex mixture
of sesquiterpenes emitted from Arabidopsis flowers.";
Plant J. 42:757-771(2005).
-!- FUNCTION: Involved in the biosynthesis of over 15 sesquiterpenes
(C15). The major products are (+)-alpha-barbatene (27.3%), (+)-
thujopsene (17.8%) and (+)-beta-chamigrene (9.9%). Can use
farnesyl diphosphate or geranyl diphosphate as substrates, but not
geranylgeranyl diphosphate. {ECO:0000269|PubMed:15918888,
ECO:0000269|PubMed:15965019}.
-!- CATALYTIC ACTIVITY: (2E,6E)-farnesyl diphosphate = (+)-alpha-
barbatene + diphosphate. {ECO:0000269|PubMed:15918888}.
-!- CATALYTIC ACTIVITY: (2E,6E)-farnesyl diphosphate = (+)-thujopsene
+ diphosphate. {ECO:0000269|PubMed:15918888}.
-!- CATALYTIC ACTIVITY: (2E,6E)-farnesyl diphosphate = (+)-beta-
chamigrene + diphosphate. {ECO:0000269|PubMed:15918888}.
-!- COFACTOR:
Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250};
Note=Binds 3 Mg(2+) or Mn(2+) ions per subunit. {ECO:0000250};
-!- BIOPHYSICOCHEMICAL PROPERTIES:
Kinetic parameters:
KM=1.2 uM for farnesyl diphosphate
{ECO:0000269|PubMed:15918888};
KM=0.21 uM for geranyl diphosphate
{ECO:0000269|PubMed:15918888};
Note=The formation of monoterpene products from geranyl
diphosphate (GPP) is unlikely, as the protein is not expected to
be present in plastids, where GPP is thought to be produced.;
-!- PATHWAY: Secondary metabolite biosynthesis; terpenoid
biosynthesis.
-!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
-!- TISSUE SPECIFICITY: Expressed exclusively in flowers. Expressed in
intrafloral nectaries and in the funiculus within the ovules.
{ECO:0000269|PubMed:12566586, ECO:0000269|PubMed:15918888}.
-!- DOMAIN: The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important
for the catalytic activity, presumably through binding to Mg(2+).
-!- DISRUPTION PHENOTYPE: Does not emit any sesquiterpene volatiles
except (E)-beta-caryophyllene, alpha-copaene and alpha-humulene.
{ECO:0000269|PubMed:15918888}.
-!- SIMILARITY: Belongs to the terpene synthase family. Tpsa
subfamily. {ECO:0000305}.
-!- SEQUENCE CAUTION:
Sequence=BAA98116.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AY876386; AAX59990.1; -; mRNA.
EMBL; AB024024; BAA98116.1; ALT_SEQ; Genomic_DNA.
EMBL; CP002688; AED95140.1; -; Genomic_DNA.
EMBL; BT030324; ABO09887.1; -; mRNA.
RefSeq; NP_199276.1; NM_123830.3.
UniGene; At.22345; -.
ProteinModelPortal; Q4KSH9; -.
SMR; Q4KSH9; -.
STRING; 3702.AT5G44630.1; -.
iPTMnet; Q4KSH9; -.
PaxDb; Q4KSH9; -.
EnsemblPlants; AT5G44630.1; AT5G44630.1; AT5G44630.
GeneID; 834491; -.
Gramene; AT5G44630.1; AT5G44630.1; AT5G44630.
KEGG; ath:AT5G44630; -.
Araport; AT5G44630; -.
TAIR; locus:2152155; AT5G44630.
eggNOG; ENOG410JVXX; Eukaryota.
eggNOG; ENOG41105GB; LUCA.
HOGENOM; HOG000232971; -.
InParanoid; Q4KSH9; -.
KO; K15799; -.
OMA; DACDTYG; -.
OrthoDB; EOG093607G1; -.
PhylomeDB; Q4KSH9; -.
BioCyc; ARA:AT5G44630-MONOMER; -.
BioCyc; MetaCyc:AT5G44630-MONOMER; -.
BRENDA; 4.2.3.69; 399.
BRENDA; 4.2.3.78; 399.
BRENDA; 4.2.3.79; 399.
SABIO-RK; Q4KSH9; -.
UniPathway; UPA00213; -.
PRO; PR:Q4KSH9; -.
Proteomes; UP000006548; Chromosome 5.
Genevisible; Q4KSH9; AT.
GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO; GO:0009506; C:plasmodesma; IDA:TAIR.
GO; GO:0102878; F:(+)-alpha-barbatene synthase activity; IEA:UniProtKB-EC.
GO; GO:0102883; F:(+)-beta-chamigrene synthase activity; IEA:UniProtKB-EC.
GO; GO:0102879; F:(+)-thujopsene synthase activity; IEA:UniProtKB-EC.
GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO; GO:0010333; F:terpene synthase activity; IEA:InterPro.
GO; GO:0051762; P:sesquiterpene biosynthetic process; IDA:TAIR.
GO; GO:0016106; P:sesquiterpenoid biosynthetic process; IDA:TAIR.
Gene3D; 1.10.600.10; -; 1.
Gene3D; 1.50.10.130; -; 1.
InterPro; IPR008949; Isoprenoid_synthase_dom.
InterPro; IPR034741; Terpene_cyclase_like_1_C.
InterPro; IPR001906; Terpene_synth_N.
InterPro; IPR036965; Terpene_synth_N_sf.
InterPro; IPR005630; Terpene_synthase_metal-bd.
InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
Pfam; PF01397; Terpene_synth; 1.
Pfam; PF03936; Terpene_synth_C; 1.
SFLD; SFLDG01019; Terpene_Cyclase_Like_1_C_Termi; 1.
SUPFAM; SSF48239; SSF48239; 1.
SUPFAM; SSF48576; SSF48576; 1.
1: Evidence at protein level;
Complete proteome; Cytoplasm; Lyase; Magnesium; Manganese;
Metal-binding; Reference proteome.
CHAIN 1 557 Alpha-barbatene synthase.
/FTId=PRO_0000380673.
MOTIF 310 314 DDXXD motif.
METAL 310 310 Magnesium or manganese 1. {ECO:0000250}.
METAL 310 310 Magnesium or manganese 2. {ECO:0000250}.
METAL 314 314 Magnesium or manganese 1. {ECO:0000250}.
METAL 314 314 Magnesium or manganese 2. {ECO:0000250}.
METAL 454 454 Magnesium or manganese 3. {ECO:0000250}.
METAL 462 462 Magnesium or manganese 3. {ECO:0000250}.
CONFLICT 162 162 F -> Y (in Ref. 1; AAX59990).
{ECO:0000305}.
SEQUENCE 557 AA; 64909 MW; 05439A5144A37240 CRC64;
MEALGNFDYE SYTNFTKLPS SQWGDQFLKF SIADSDFDVL EREIEVLKPK VRENIFVSSS
TDKDAMKKTI LSIHFLDSLG LSYHFEKEIE ESLKHAFEKI EDLIADENKL HTISTIFRVF
RTYGYYMSSD VFKIFKGDDG KFKESLIEDV KGMLSFYEAV HFGTTTDHIL DEALSFTLNH
LESLATGRRA SPPHISKLIQ NALHIPQHRN IQALVAREYI SFYEHEEDHD ETLLKLAKLN
FKFLQLHYFQ ELKTITMWWT KLDHTSNLPP NFRERTVETW FAALMMYFEP QFSLGRIMSA
KLYLVITFLD DACDTYGSIS EVESLADCLE RWDPDYMENL QGHMKTAFKF VMYLFKEYEE
ILRSQGRSFV LEKMIEEFKI IARKNLELVK WARGGHVPSF DEYIESGGAE IGTYATIACS
IMGLGEIGKK EAFEWLISRP KLVRILGAKT RLMDDIADFE EDMEKGYTAN ALNYYMNEHG
VTKEEASREL EKMNGDMNKI VNEECLKITT MPRRILMQSV NYARSLDVLY TADDVYNHRE
GKLKEYMRLL LVDPILL


Related products :

Catalog number Product name Quantity
E0167h ELISA kit Beta-trace protein,Cerebrin-28,Glutathione-independent PGD synthase,Homo sapiens,Human,Lipocalin-type prostaglandin-D synthase,PDS,PGD2 synthase,PGDS,PGDS2,Prostaglandin-D2 synthase,Prostag 96T
E0167h ELISA Beta-trace protein,Cerebrin-28,Glutathione-independent PGD synthase,Homo sapiens,Human,Lipocalin-type prostaglandin-D synthase,PDS,PGD2 synthase,PGDS,PGDS2,Prostaglandin-D2 synthase,Prostaglandi 96T
U0167h CLIA Beta-trace protein,Cerebrin-28,Glutathione-independent PGD synthase,Homo sapiens,Human,Lipocalin-type prostaglandin-D synthase,PDS,PGD2 synthase,PGDS,PGDS2,Prostaglandin-D2 synthase,Prostaglandin 96T
EIAAB06601 CDP-DAG synthase 2,CDP-DG synthase 2,CDP-diacylglycerol synthase 2,CDP-diglyceride pyrophosphorylase 2,CDP-diglyceride synthase 2,CDS 2,CDS2,CTP phosphatidate cytidylyltransferase 2,Homo sapiens,Human
EIAAB06600 Bos taurus,Bovine,CDP-DAG synthase 2,CDP-DG synthase 2,CDP-diacylglycerol synthase 2,CDP-diglyceride pyrophosphorylase 2,CDP-diglyceride synthase 2,CDS 2,CDS2,CTP phosphatidate cytidylyltransferase 2,
EIAAB06597 CDP-DAG synthase 1,CDP-DG synthase 1,CDP-diacylglycerol synthase 1,CDP-diglyceride pyrophosphorylase 1,CDP-diglyceride synthase 1,CDS,CDS 1,CDS1,CTP phosphatidate cytidylyltransferase 1,Homo sapiens,H
EIAAB06599 CDP-DAG synthase 1,CDP-DG synthase 1,CDP-diacylglycerol synthase 1,CDP-diglyceride pyrophosphorylase 1,CDP-diglyceride synthase 1,Cds,CDS 1,Cds1,CTP phosphatidate cytidylyltransferase 1,Mouse,Mus musc
EIAAB06603 CDP-DAG synthase 2,CDP-DG synthase 2,CDP-diacylglycerol synthase 2,CDP-diglyceride pyrophosphorylase 2,CDP-diglyceride synthase 2,CDS 2,Cds2,CTP phosphatidate cytidylyltransferase 2,Mouse,Mus musculus
EIAAB28570 (2-5')oligo(A) synthase 1B,2-5A synthase 1B,2'-5'-oligoadenylate synthase 1B,2'-5'-oligoadenylate synthase-like protein 1,Mouse,Mus musculus,Oas1b,Oias2
E0167m ELISA Glutathione-independent PGD synthase,Lipocalin-type prostaglandin-D synthase,L-PGDS,Mouse,Mus musculus,PGD2 synthase,PGDS2,Prostaglandin-D2 synthase,Prostaglandin-H2 D-isomerase,Ptgds 96T
E0167b ELISA Bos taurus,Bovine,Glutathione-independent PGD synthase,Lipocalin-type prostaglandin-D synthase,PGD2 synthase,PGDS,PGDS2,Prostaglandin-D2 synthase,Prostaglandin-H2 D-isomerase,PTGDS 96T
E0167r ELISA kit Glutathione-independent PGD synthase,Lipocalin-type prostaglandin-D synthase,PGD2 synthase,PGDS,PGDS2,Prostaglandin-D2 synthase,Prostaglandin-H2 D-isomerase,Ptgds,Rat,Rattus norvegicus 96T
U0167r CLIA Glutathione-independent PGD synthase,Lipocalin-type prostaglandin-D synthase,PGD2 synthase,PGDS,PGDS2,Prostaglandin-D2 synthase,Prostaglandin-H2 D-isomerase,Ptgds,Rat,Rattus norvegicus 96T
E0167r ELISA Glutathione-independent PGD synthase,Lipocalin-type prostaglandin-D synthase,PGD2 synthase,PGDS,PGDS2,Prostaglandin-D2 synthase,Prostaglandin-H2 D-isomerase,Ptgds,Rat,Rattus norvegicus 96T
U0167m CLIA Glutathione-independent PGD synthase,Lipocalin-type prostaglandin-D synthase,L-PGDS,Mouse,Mus musculus,PGD2 synthase,PGDS2,Prostaglandin-D2 synthase,Prostaglandin-H2 D-isomerase,Ptgds 96T
E0167b ELISA kit Bos taurus,Bovine,Glutathione-independent PGD synthase,Lipocalin-type prostaglandin-D synthase,PGD2 synthase,PGDS,PGDS2,Prostaglandin-D2 synthase,Prostaglandin-H2 D-isomerase,PTGDS 96T
E0167m ELISA kit Glutathione-independent PGD synthase,Lipocalin-type prostaglandin-D synthase,L-PGDS,Mouse,Mus musculus,PGD2 synthase,PGDS2,Prostaglandin-D2 synthase,Prostaglandin-H2 D-isomerase,Ptgds 96T
U0167b CLIA Bos taurus,Bovine,Glutathione-independent PGD synthase,Lipocalin-type prostaglandin-D synthase,PGD2 synthase,PGDS,PGDS2,Prostaglandin-D2 synthase,Prostaglandin-H2 D-isomerase,PTGDS 96T
E0167p ELISA Glutathione-independent PGD synthase,Lipocalin-type prostaglandin-D synthase,PGD2 synthase,PGDS,PGDS2,Pig,Prostaglandin-D2 synthase,Prostaglandin-H2 D-isomerase,PTGDS,Sus scrofa 96T
U0167p CLIA Glutathione-independent PGD synthase,Lipocalin-type prostaglandin-D synthase,PGD2 synthase,PGDS,PGDS2,Pig,Prostaglandin-D2 synthase,Prostaglandin-H2 D-isomerase,PTGDS,Sus scrofa 96T
E0167p ELISA kit Glutathione-independent PGD synthase,Lipocalin-type prostaglandin-D synthase,PGD2 synthase,PGDS,PGDS2,Pig,Prostaglandin-D2 synthase,Prostaglandin-H2 D-isomerase,PTGDS,Sus scrofa 96T
U0122Rb CLIA COX1,COX-1,Cyclooxygenase-1,Oryctolagus cuniculus,PGH synthase 1,PGHS-1,PHS 1,Prostaglandin G_H synthase 1,Prostaglandin H2 synthase 1,Prostaglandin-endoperoxide synthase 1,PTGS1,Rabbit 96T
E0122h ELISA COX1,COX-1,Cyclooxygenase-1,Homo sapiens,Human,PGH synthase 1,PGHS-1,PHS 1,Prostaglandin G_H synthase 1,Prostaglandin H2 synthase 1,Prostaglandin-endoperoxide synthase 1,PTGS1 96T
E0122Rb ELISA COX1,COX-1,Cyclooxygenase-1,Oryctolagus cuniculus,PGH synthase 1,PGHS-1,PHS 1,Prostaglandin G_H synthase 1,Prostaglandin H2 synthase 1,Prostaglandin-endoperoxide synthase 1,PTGS1,Rabbit 96T
E0699h ELISA kit COX2,COX-2,Cyclooxygenase-2,Homo sapiens,Human,PGH synthase 2,PGHS-2,PHS II,Prostaglandin G_H synthase 2,Prostaglandin H2 synthase 2,Prostaglandin-endoperoxide synthase 2,PTGS2 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur