Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Amino acid permease 6 (Amino acid transporter AAP6)

 AAP6_ARATH              Reviewed;         481 AA.
P92934;
03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
01-MAY-1997, sequence version 1.
07-JUN-2017, entry version 101.
RecName: Full=Amino acid permease 6;
AltName: Full=Amino acid transporter AAP6;
Name=AAP6; OrderedLocusNames=At5g49630; ORFNames=MNI5.1;
Arabidopsis thaliana (Mouse-ear cress).
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
Arabidopsis.
NCBI_TaxID=3702;
[1]
NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, INDUCTION, AND TISSUE
SPECIFICITY.
STRAIN=cv. Landsberg erecta;
PubMed=8776904; DOI=10.1105/tpc.8.8.1437;
Rentsch D., Hirner B., Schmelzer E., Frommer W.B.;
"Salt stress-induced proline transporters and salt stress-repressed
broad specificity amino acid permeases identified by suppression of a
yeast amino acid permease-targeting mutant.";
Plant Cell 8:1437-1446(1996).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
PubMed=10718197; DOI=10.1093/dnares/7.1.31;
Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
Tabata S.;
"Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
features of the regions of 3,076,755 bp covered by sixty P1 and TAC
clones.";
DNA Res. 7:31-63(2000).
[3]
GENOME REANNOTATION.
STRAIN=cv. Columbia;
The Arabidopsis Information Portal (Araport);
Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J.,
Hayashizaki Y., Shinozaki K.;
"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
[5]
TISSUE SPECIFICITY, AND BIOPHYSICOCHEMICAL PROPERTIES.
PubMed=12244056; DOI=10.1074/jbc.M207730200;
Okumoto S., Schmidt R., Tegeder M., Fischer W.-N., Rentsch D.,
Frommer W.B., Koch W.;
"High affinity amino acid transporters specifically expressed in xylem
parenchyma and developing seeds of Arabidopsis.";
J. Biol. Chem. 277:45338-45346(2002).
[6]
CHARACTERIZATION.
PubMed=12148530; DOI=10.1046/j.1365-313X.2002.01248.x;
Fischer W.-N., Loo D.D.F., Koch W., Ludewig U., Boorer K.J.,
Tegeder M., Rentsch D., Wright E.M., Frommer W.B.;
"Low and high affinity amino acid H+-cotransporters for cellular
import of neutral and charged amino acids.";
Plant J. 29:717-731(2002).
[7]
DISRUPTION PHENOTYPE.
PubMed=19755569; DOI=10.1093/jxb/erp274;
Hunt E., Gattolin S., Newbury H.J., Bale J.S., Tseng H.-M.,
Barrett D.A., Pritchard J.;
"A mutation in amino acid permease AAP6 reduces the amino acid content
of the Arabidopsis sieve elements but leaves aphid herbivores
unaffected.";
J. Exp. Bot. 61:55-64(2010).
-!- FUNCTION: Amino acid-proton symporter. Stereospecific transporter
with a broad specificity for tryptophan, proline, and neutral and
acidic amino acids. Have an affinity for aspartate in a
physiological range. Involved in the uptake of amino acids
diffusing out of the xylem tracheids into the xylem parenchyma.
{ECO:0000269|PubMed:8776904}.
-!- BIOPHYSICOCHEMICAL PROPERTIES:
Kinetic parameters:
KM=248 uM for aspartate {ECO:0000269|PubMed:12244056};
Vmax=0.342 nmol/min/mg enzyme toward aspartate
{ECO:0000269|PubMed:12244056};
-!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass
membrane protein {ECO:0000305}.
-!- TISSUE SPECIFICITY: Expressed in roots and leaves, and at lower
levels in stems and flowers. Found in the xylem parenchyma.
{ECO:0000269|PubMed:12244056, ECO:0000269|PubMed:8776904}.
-!- DEVELOPMENTAL STAGE: Expressed at higher levels in sink as
compared with source leaves.
-!- INDUCTION: Down-regulated by drought and salt stress.
{ECO:0000269|PubMed:8776904}.
-!- DISRUPTION PHENOTYPE: Larger seeds and rosette leaves and
increased number of cauline leaves at flowering. Decreased
concentration of lysine, phenylalanine, leucine and aspartic acid
in the sieve element sap, but no significant effect on aphid
feeding behavior or reproduction. {ECO:0000269|PubMed:19755569}.
-!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2
family. Amino acid/auxin permease (AAAP) (TC 2.A.18.2) subfamily.
{ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; X95736; CAA65051.1; -; mRNA.
EMBL; AB025627; BAA97227.1; -; Genomic_DNA.
EMBL; CP002688; AED95838.1; -; Genomic_DNA.
EMBL; AK229102; BAF00980.1; -; mRNA.
PIR; T50691; T50691.
RefSeq; NP_199774.1; NM_124341.4.
UniGene; At.163; -.
ProteinModelPortal; P92934; -.
BioGrid; 20271; 3.
STRING; 3702.AT5G49630.1; -.
TCDB; 2.A.18.2.4; the amino acid/auxin permease (aaap) family.
SwissPalm; P92934; -.
PaxDb; P92934; -.
PRIDE; P92934; -.
EnsemblPlants; AT5G49630.1; AT5G49630.1; AT5G49630.
GeneID; 835025; -.
Gramene; AT5G49630.1; AT5G49630.1; AT5G49630.
KEGG; ath:AT5G49630; -.
Araport; AT5G49630; -.
TAIR; locus:2168912; AT5G49630.
eggNOG; KOG1303; Eukaryota.
eggNOG; COG0814; LUCA.
HOGENOM; HOG000238530; -.
InParanoid; P92934; -.
OMA; SMGAIKR; -.
OrthoDB; EOG09360984; -.
PhylomeDB; P92934; -.
SABIO-RK; P92934; -.
PRO; PR:P92934; -.
Proteomes; UP000006548; Chromosome 5.
ExpressionAtlas; P92934; baseline and differential.
Genevisible; P92934; AT.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005886; C:plasma membrane; IDA:TAIR.
GO; GO:0015172; F:acidic amino acid transmembrane transporter activity; IDA:TAIR.
GO; GO:0015175; F:neutral amino acid transmembrane transporter activity; IDA:TAIR.
GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
GO; GO:0015810; P:aspartate transport; IDA:TAIR.
GO; GO:0015827; P:tryptophan transport; IDA:TAIR.
InterPro; IPR013057; AA_transpt_TM.
Pfam; PF01490; Aa_trans; 1.
1: Evidence at protein level;
Amino-acid transport; Cell membrane; Complete proteome; Membrane;
Reference proteome; Symport; Transmembrane; Transmembrane helix;
Transport.
CHAIN 1 481 Amino acid permease 6.
/FTId=PRO_0000387504.
TOPO_DOM 1 36 Cytoplasmic. {ECO:0000255}.
TRANSMEM 37 57 Helical. {ECO:0000255}.
TRANSMEM 58 78 Helical. {ECO:0000255}.
TOPO_DOM 79 125 Cytoplasmic. {ECO:0000255}.
TRANSMEM 126 146 Helical. {ECO:0000255}.
TOPO_DOM 147 167 Extracellular. {ECO:0000255}.
TRANSMEM 168 188 Helical. {ECO:0000255}.
TOPO_DOM 189 190 Cytoplasmic. {ECO:0000255}.
TRANSMEM 191 211 Helical. {ECO:0000255}.
TOPO_DOM 212 242 Extracellular. {ECO:0000255}.
TRANSMEM 243 263 Helical. {ECO:0000255}.
TOPO_DOM 264 283 Cytoplasmic. {ECO:0000255}.
TRANSMEM 284 304 Helical. {ECO:0000255}.
TOPO_DOM 305 321 Extracellular. {ECO:0000255}.
TRANSMEM 322 342 Helical. {ECO:0000255}.
TOPO_DOM 343 385 Cytoplasmic. {ECO:0000255}.
TRANSMEM 386 405 Helical. {ECO:0000255}.
TOPO_DOM 406 408 Extracellular. {ECO:0000255}.
TRANSMEM 409 427 Helical. {ECO:0000255}.
TOPO_DOM 428 447 Cytoplasmic. {ECO:0000255}.
TRANSMEM 448 468 Helical. {ECO:0000255}.
TOPO_DOM 469 481 Extracellular. {ECO:0000255}.
SEQUENCE 481 AA; 53021 MW; DEB1CA7348760AD1 CRC64;
MEKKKSMFVE QSFPEHEIGD TNKNFDEDGR DKRTGTWMTG SAHIITAVIG SGVLSLAWAI
AQLGWVAGPA VLMAFSFITY FTSTMLADCY RSPDPVTGKR NYTYMEVVRS YLGGRKVQLC
GLAQYGNLIG ITIGYTITAS ISMVAVKRSN CFHKNGHNVK CATSNTPFMI IFAIIQIILS
QIPNFHNLSW LSILAAVMSF CYASIGVGLS IAKAAGGGEH VRTTLTGVTV GIDVSGAEKI
WRTFQAIGDI AFAYAYSTVL IEIQDTLKAG PPSENKAMKR ASLVGVSTTT FFYMLCGCVG
YAAFGNDAPG NFLTGFGFYE PFWLIDFANV CIAVHLIGAY QVFCQPIFQF VESQSAKRWP
DNKFITGEYK IHVPCCGDFS INFLRLVWRT SYVVVTAVVA MIFPFFNDFL GLIGAASFWP
LTVYFPIEMH IAQKKIPKFS FTWTWLKILS WTCFIVSLVA AAGSVQGLIQ SLKDFKPFQA
P


Related products :

Catalog number Product name Quantity
EIAAB46684 Homo sapiens,Human,Monocyte amino acid permease 2,MOP-2,SLC7A7,Solute carrier family 7 member 7,y(+)L-type amino acid transporter 1,Y+L amino acid transporter 1,Y+LAT1,y+LAT-1
EIAAB36967 Amino acid transporter A1,Ata1,Glnt,Glutamine transporter,N-system amino acid transporter 2,Rat,rATA1,Rattus norvegicus,Sa2,Sat1,Slc38a1,Snat1,Sodium-coupled neutral amino acid transporter 1,Solute ca
EIAAB36968 Amino acid transporter A1,MNat2,Mouse,Mus musculus,Nat2,N-system amino acid transporter 2,Slc38a1,Snat1,Sodium-coupled neutral amino acid transporter 1,Solute carrier family 38 member 1,System A amino
EIAAB46686 Cationic amino acid transporter, y+ system,Homo sapiens,Human,KIAA0245,SLC7A6,Solute carrier family 7 member 6,y(+)L-type amino acid transporter 2,Y+L amino acid transporter 2,Y+LAT2,y+LAT-2
EIAAB37135 Amino acid transporter ATB0+,Colonic system B0+ amino acid transporter CATB0+,Mouse,Mus musculus,Slc6a14,Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+),Solute carrier fa
EIAAB36958 Lyaat1,LYAAT-1,Lysosomal amino acid transporter 1,Neutral amino acid_proton symporter,Pat1,Proton_amino acid transporter 1,Proton-coupled amino acid transporter 1,Rat,Rattus norvegicus,Slc36a1,Solute
EIAAB36970 Amino acid transporter A2,Ata2,Kiaa1382,Mouse,Mus musculus,Sat2,Slc38a2,Snat2,Sodium-coupled neutral amino acid transporter 2,Solute carrier family 38 member 2,System A amino acid transporter 2,System
EIAAB36974 Amino acid transporter A2,Ata2,Rat,Rattus norvegicus,Sa1,Sat2,Slc38a2,Snat2,Sodium-coupled neutral amino acid transporter 2,Solute carrier family 38 member 2,System A amino acid transporter 2,System A
EIAAB36969 Amino acid transporter A1,ATA1,Homo sapiens,Human,NAT2,N-system amino acid transporter 2,SAT1,SLC38A1,SNAT1,Sodium-coupled neutral amino acid transporter 1,Solute carrier family 38 member 1,System A a
EIAAB36972 Amino acid transporter A2,Bos taurus,Bovine,Protein 40-9-1,SLC38A2,SNAT2,Sodium-coupled neutral amino acid transporter 2,Solute carrier family 38 member 2,System A amino acid transporter 2,System A tr
EIAAB36973 Amino acid transporter A2,ATA2,Homo sapiens,Human,KIAA1382,Protein 40-9-1,SAT2,SLC38A2,SNAT2,Sodium-coupled neutral amino acid transporter 2,Solute carrier family 38 member 2,System A amino acid trans
EIAAB36978 Amino acid transporter A3,ATA3,Homo sapiens,Human,Na(+)-coupled neutral amino acid transporter 4,NAT3,SLC38A4,SNAT4,Sodium-coupled neutral amino acid transporter 4,Solute carrier family 38 member 4,Sy
EIAAB36986 Homo sapiens,Human,Na(+)-coupled neutral amino acid transporter 6,NAT1,NAT-1,N-system amino acid transporter 1,Probable sodium-coupled neutral amino acid transporter 6,SLC38A6,SNAT6,Solute carrier fam
EIAAB36977 G17,Homo sapiens,Human,Na(+)-coupled neutral amino acid transporter 3,NAT1,N-system amino acid transporter 1,SLC38A3,SN1,SNAT3,Sodium-coupled neutral amino acid transporter 3,Solute carrier family 38
EIAAB36971 Amino acid transporter A2,Chicken,Gallus gallus,RCJMB04_2k20,SLC38A2,SNAT2,Sodium-coupled neutral amino acid transporter 2,Solute carrier family 38 member 2,System A amino acid transporter 2,System A
EIAAB36976 mNAT,Mouse,Mus musculus,Na(+)-coupled neutral amino acid transporter 3,N-system amino acid transporter 1,Slc38a3,Sn1,Snat3,Sodium-coupled neutral amino acid transporter 3,Solute carrier family 38 memb
EIAAB36979 Amino acid transporter A3,Ata3,Na(+)-coupled neutral amino acid transporter 4,Rat,Rattus norvegicus,Slc38a4,Snat4,Sodium-coupled neutral amino acid transporter 4,Solute carrier family 38 member 4,Syst
EIAAB36980 Amino acid transporter A3,Ata3,Mouse,Mus musculus,Na(+)-coupled neutral amino acid transporter 4,Nat3,Slc38a4,Snat4,Sodium-coupled neutral amino acid transporter 4,Solute carrier family 38 member 4,Sy
EIAAB36975 Na(+)-coupled neutral amino acid transporter 3,N-system amino acid transporter 1,Rat,Rattus norvegicus,Slc38a3,Snat3,Sodium-coupled neutral amino acid transporter 3,Solute carrier family 38 member 3,S
EIAAB36985 Na(+)-coupled neutral amino acid transporter 6,Nat1,NAT-1,N-system amino acid transporter 1,Probable sodium-coupled neutral amino acid transporter 6,Rat,Rattus norvegicus,Slc38a6,Snat6,Solute carrier
18-003-43741 Sodium-coupled neutral amino acid transporter 4 - Na(+)-coupled neutral amino acid transporter 4; Amino acid transporter A3; System A amino acid transporter 3; System N amino acid transporter 3; Solut 0.1 mg Protein A
EIAAB25184 Aromatic amino acid transporter 1,MCT 10,Mct10,Monocarboxylate transporter 10,Rat,Rattus norvegicus,Slc16a10,Solute carrier family 16 member 10,Tat1,T-type amino acid transporter 1
EIAAB25183 Aromatic amino acid transporter 1,MCT 10,Mct10,Monocarboxylate transporter 10,Mouse,Mus musculus,Slc16a10,Solute carrier family 16 member 10,Tat1,T-type amino acid transporter 1
EIAAB25185 Aromatic amino acid transporter 1,Homo sapiens,Human,MCT 10,MCT10,Monocarboxylate transporter 10,SLC16A10,Solute carrier family 16 member 10,TAT1,T-type amino acid transporter 1
EIAAB46683 Rat,Rattus norvegicus,Slc7a7,Solute carrier family 7 member 7,y(+)L-type amino acid transporter 1,Y+L amino acid transporter 1,Y+LAT1,y+LAT-1


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur