Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Aminoglycoside 3'-phosphotransferase (EC 2.7.1.95) (APH(3')V) (Kanamycin kinase, type V) (Neomycin-kanamycin phosphotransferase type V)

 KKA5_STRFR              Reviewed;         268 AA.
P00555;
21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
21-JUL-1986, sequence version 1.
23-MAY-2018, entry version 68.
RecName: Full=Aminoglycoside 3'-phosphotransferase;
EC=2.7.1.95;
AltName: Full=APH(3')V;
AltName: Full=Kanamycin kinase, type V;
AltName: Full=Neomycin-kanamycin phosphotransferase type V;
Name=aph;
Streptomyces fradiae (Streptomyces roseoflavus).
Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
Streptomyces.
NCBI_TaxID=1906;
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=ATCC 10745 / CBS 498.68 / DSM 40063 / JCM 4133 / NBRC 12773 /
NCIMB 8233 / NRRL B-1195 / VKM Ac-150;
PubMed=6310563; DOI=10.1073/pnas.80.17.5190;
Thompson C.J., Gray G.S.;
"Nucleotide sequence of a streptomycete aminoglycoside
phosphotransferase gene and its relationship to phosphotransferases
encoded by resistance plasmids.";
Proc. Natl. Acad. Sci. U.S.A. 80:5190-5194(1983).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-71.
PubMed=2987648; DOI=10.1007/BF00327505;
Bibb M.J., Bibb M.J., Ward J.M., Cohen S.N.;
"Nucleotide sequences encoding and promoting expression of three
antibiotic resistance genes indigenous to Streptomyces.";
Mol. Gen. Genet. 199:26-36(1985).
-!- FUNCTION: Resistance to kanamycin and structurally-related
aminoglycosides, including amikacin.
-!- CATALYTIC ACTIVITY: ATP + kanamycin = ADP + kanamycin 3'-
phosphate.
-!- SIMILARITY: Belongs to the aminoglycoside phosphotransferase
family. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; K00432; AAA26699.1; -; Genomic_DNA.
EMBL; X02394; CAA26236.1; -; Genomic_DNA.
EMBL; A04924; CAA00404.1; -; Unassigned_DNA.
PIR; A00666; PKSMR.
RefSeq; WP_063842176.1; NG_047450.1.
ProteinModelPortal; P00555; -.
SMR; P00555; -.
PRIDE; P00555; -.
KEGG; ag:AAA26699; -.
KO; K00897; -.
GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO; GO:0008910; F:kanamycin kinase activity; IEA:UniProtKB-EC.
GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
CDD; cd05150; APH; 1.
InterPro; IPR002575; Aminoglycoside_PTrfase.
InterPro; IPR024165; Kan/Strep_kinase.
InterPro; IPR011009; Kinase-like_dom_sf.
Pfam; PF01636; APH; 1.
PIRSF; PIRSF000706; Kanamycin_kin; 1.
SUPFAM; SSF56112; SSF56112; 1.
3: Inferred from homology;
Antibiotic resistance; ATP-binding; Kinase; Nucleotide-binding;
Transferase.
CHAIN 1 268 Aminoglycoside 3'-phosphotransferase.
/FTId=PRO_0000204808.
ACT_SITE 188 188 Proton acceptor. {ECO:0000250}.
SEQUENCE 268 AA; 29986 MW; 868C622038FE1C14 CRC64;
MDDSTLRRKY PHHEWHAVNE GDSGAFVYQL TGGPEPQPEL YAKIAPRAPE NSAFDLSGEA
DRLEWLHRHG IPVPRVVERG ADDTAAWLVT EAVPGVAAAE EWPEHQRFAV VEAMAELARA
LHELPVEDCP SDRRLDAAVA EARRNVAEGL VDLDDLQEER AGWTGDQLLA ELDRTRPEKE
DLVVCHGDLC PNNVLLDPGT CRVTGVIDVG RLGVADRHAD IALAARELEI DEDPWFGPAY
AERFLERYGA HRVDKEKLAF YQLLDEFF


Related products :

Catalog number Product name Quantity
E7969h Human Aminoglycoside Phosphotransferase Domain Con 96T
AGR2 AGPHD1 Gene aminoglycoside phosphotransferase domain containing 1
AGPD1_BOVIN Bovine ELISA Kit FOR Aminoglycoside phosphotransferase domain-containing protein 1 96T
AGPD1_HUMAN Human ELISA Kit FOR Aminoglycoside phosphotransferase domain-containing protein 1 96T
Y104285 Neomycin Phosphotransferase II (NPT II) 500ul
AGPD1_BOVIN ELISA Kit FOR Aminoglycoside phosphotransferase domain-containing protein 1; organism: Bovine; gene name: AGPHD1 96T
Y104285 Neomycin Phosphotransferase II (NPT II) Antibody 500ul
GWB-69FD13 Anti- Neomycin Phosphotransferase II (NPT II) Antibody
MA-20057 Mouse Monoclonal Anti-Human Neomycin phosphotransferase II (NPT II) 100 ul
AM19000PU-N Kanamycin kinase type II Mouse IgG2a antibody Ab Purified 0.1 mg
'AM19000PU-N Kanamycin kinase type II IgG2a antibody Ab host: Mouse 0.1 mg
M1709 pCAMBIA2300 Vector (No Reporter Gene Kanamycin per Kanamycin Resistant Plant Expression Vector), pUC18 poly-linker, genes for bacterial and plant selection with kanamycin, no reporter gene allowing co
'AM19000PU-N Kanamycin kinase type II Clone '4B4D1 antibody Isotype IgG2a Host Mouse 0.1 mg
32-199 Neomycin phosphotransferase II (nptII) gene is used in selection of transformed organisms. It was initially isolated from the transposon Tn5 that was present in the bacterium strain Escherichia coli K 0.1 mg
PAS9531 Polyclonal antibody, Anti-Inflammatory Drugs: Aminoglycoside, KANAMYCIN, Host animal: Sheep, Format: Ig Fraction - Liquid, Ig concentration: >5 1ml
PAS9803 Polyclonal antibody, Anti-Inflammatory Drugs: Aminoglycoside, KANAMYCIN, Host animal: Sheep, Format: Ig Fraction - Liquid, Ig concentration: >5 100
MA-20057 Mouse Monoclonal Anti-Human Neomycin phosphotransferase II (NPT II) Species Reactivity: Human 100 ul Product tipe: Antibodies
CSB-EL005374RA Rat choline phosphotransferase 1 (CHPT1) ELISA kit, Species Rat, Sample Type serum, plasma 96T
CSB-EL005253RA Rat choline_ethanolamine phosphotransferase 1 (CEPT1) ELISA kit, Species Rat, Sample Type serum, plasma 96T
M1708 pCAMBIA2200 Vector (No Reporter Gene Kanamycin per Chloramphenicol Resistant Plant Expression Vector), Restriction sites for modular plasmid modifications, pUC18 poly-linker, kanamycin and chloramphen
M1592 pCAMBIA1301 Vector (gusA Hygromycin B per Kanamycin Resistant Plant Expression Vector), Restriction sites for modular plasmid modifications, pUC18 poly-linker, kanamycin and hygromycin B resistance ge
M1596 pCAMBIA1305.1 Vector (GusPlus™ Hygromycin B per Kanamycin Resistant Plant Expression Vector), Restriction sites for modular plasmid modifications, pUC18 poly-linker, kanamycin and hygromycin B resista
M1597 pCAMBIA1305.2 Vector (Secretory GusPlus™ Hygromycin B per Kanamycin Resistant Plant Expression Vector), Restriction sites for modular plasmid modifications, pUC18 poly-linker, kanamycin and hygromycin
M1593 pCAMBIA1302 Vector (mgfp5 Hygromycin B per Kanamycin Resistant Plant Expression Vector), Restriction sites for modular plasmid modifications, pUC18 poly-linker, kanamycin and hygromycin B resistance,
M1591 pCAMBIA1300 Vector (No Reporter Gene Hygromycin B per Kanamycin Resistant Plant Expression Vector), Restriction sites for modular plasmid modifications, pUC18 poly-linker, kanamycin and hygromycin B r


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur