Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Apolipoprotein A-II (Apo-AII) (ApoA-II) (Apolipoprotein A2) [Cleaved into: Proapolipoprotein A-II (ProapoA-II); Truncated apolipoprotein A-II (Apolipoprotein A-II(1-76))]

 APOA2_CANLF             Reviewed;         100 AA.
E2RAK7;
19-MAR-2014, integrated into UniProtKB/Swiss-Prot.
31-OCT-2012, sequence version 2.
23-MAY-2018, entry version 61.
RecName: Full=Apolipoprotein A-II;
Short=Apo-AII;
Short=ApoA-II;
AltName: Full=Apolipoprotein A2;
Contains:
RecName: Full=Proapolipoprotein A-II;
Short=ProapoA-II;
Contains:
RecName: Full=Truncated apolipoprotein A-II;
AltName: Full=Apolipoprotein A-II(1-76);
Flags: Precursor;
Name=APOA2;
Canis lupus familiaris (Dog) (Canis familiaris).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;
Canis.
NCBI_TaxID=9615;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Boxer;
PubMed=16341006; DOI=10.1038/nature04338;
Lindblad-Toh K., Wade C.M., Mikkelsen T.S., Karlsson E.K., Jaffe D.B.,
Kamal M., Clamp M., Chang J.L., Kulbokas E.J. III, Zody M.C.,
Mauceli E., Xie X., Breen M., Wayne R.K., Ostrander E.A.,
Ponting C.P., Galibert F., Smith D.R., deJong P.J., Kirkness E.F.,
Alvarez P., Biagi T., Brockman W., Butler J., Chin C.-W., Cook A.,
Cuff J., Daly M.J., DeCaprio D., Gnerre S., Grabherr M., Kellis M.,
Kleber M., Bardeleben C., Goodstadt L., Heger A., Hitte C., Kim L.,
Koepfli K.-P., Parker H.G., Pollinger J.P., Searle S.M.J.,
Sutter N.B., Thomas R., Webber C., Baldwin J., Abebe A.,
Abouelleil A., Aftuck L., Ait-Zahra M., Aldredge T., Allen N., An P.,
Anderson S., Antoine C., Arachchi H., Aslam A., Ayotte L.,
Bachantsang P., Barry A., Bayul T., Benamara M., Berlin A.,
Bessette D., Blitshteyn B., Bloom T., Blye J., Boguslavskiy L.,
Bonnet C., Boukhgalter B., Brown A., Cahill P., Calixte N.,
Camarata J., Cheshatsang Y., Chu J., Citroen M., Collymore A.,
Cooke P., Dawoe T., Daza R., Decktor K., DeGray S., Dhargay N.,
Dooley K., Dooley K., Dorje P., Dorjee K., Dorris L., Duffey N.,
Dupes A., Egbiremolen O., Elong R., Falk J., Farina A., Faro S.,
Ferguson D., Ferreira P., Fisher S., FitzGerald M., Foley K.,
Foley C., Franke A., Friedrich D., Gage D., Garber M., Gearin G.,
Giannoukos G., Goode T., Goyette A., Graham J., Grandbois E.,
Gyaltsen K., Hafez N., Hagopian D., Hagos B., Hall J., Healy C.,
Hegarty R., Honan T., Horn A., Houde N., Hughes L., Hunnicutt L.,
Husby M., Jester B., Jones C., Kamat A., Kanga B., Kells C.,
Khazanovich D., Kieu A.C., Kisner P., Kumar M., Lance K., Landers T.,
Lara M., Lee W., Leger J.-P., Lennon N., Leuper L., LeVine S., Liu J.,
Liu X., Lokyitsang Y., Lokyitsang T., Lui A., Macdonald J., Major J.,
Marabella R., Maru K., Matthews C., McDonough S., Mehta T.,
Meldrim J., Melnikov A., Meneus L., Mihalev A., Mihova T., Miller K.,
Mittelman R., Mlenga V., Mulrain L., Munson G., Navidi A., Naylor J.,
Nguyen T., Nguyen N., Nguyen C., Nguyen T., Nicol R., Norbu N.,
Norbu C., Novod N., Nyima T., Olandt P., O'Neill B., O'Neill K.,
Osman S., Oyono L., Patti C., Perrin D., Phunkhang P., Pierre F.,
Priest M., Rachupka A., Raghuraman S., Rameau R., Ray V., Raymond C.,
Rege F., Rise C., Rogers J., Rogov P., Sahalie J., Settipalli S.,
Sharpe T., Shea T., Sheehan M., Sherpa N., Shi J., Shih D., Sloan J.,
Smith C., Sparrow T., Stalker J., Stange-Thomann N., Stavropoulos S.,
Stone C., Stone S., Sykes S., Tchuinga P., Tenzing P., Tesfaye S.,
Thoulutsang D., Thoulutsang Y., Topham K., Topping I., Tsamla T.,
Vassiliev H., Venkataraman V., Vo A., Wangchuk T., Wangdi T.,
Weiand M., Wilkinson J., Wilson A., Yadav S., Yang S., Yang X.,
Young G., Yu Q., Zainoun J., Zembek L., Zimmer A., Lander E.S.;
"Genome sequence, comparative analysis and haplotype structure of the
domestic dog.";
Nature 438:803-819(2005).
[2]
PROTEIN SEQUENCE OF 79-94, AND MASS SPECTROMETRY.
TISSUE=Plasma;
PubMed=20483223; DOI=10.1016/j.cbd.2008.08.002;
Puppione D.L., Bassilian S., Souda P., MacDonald M.H., Halgand F.,
Hagland F., Whitelegge J.P.;
"Mass spectral analysis of the apolipoproteins on dog (Canis lupus
familiaris) high density lipoproteins. Detection of apolipoprotein A-
II.";
Comp. Biochem. Physiol. 3:290-296(2008).
-!- FUNCTION: May stabilize HDL (high density lipoprotein) structure
by its association with lipids, and affect the HDL metabolism.
-!- SUBUNIT: Monomer. Interacts with APOA1BP and NDRG1 (By
similarity). {ECO:0000250|UniProtKB:P02652}.
-!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P02652}.
-!- TISSUE SPECIFICITY: Plasma.
-!- MASS SPECTROMETRY: Mass=8681.5; Mass_error=0.354;
Method=Electrospray; Range=24-100;
Evidence={ECO:0000269|PubMed:20483223};
-!- SIMILARITY: Belongs to the apolipoprotein A2 family.
{ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; AAEX03018445; -; NOT_ANNOTATED_CDS; Genomic_DNA.
RefSeq; NP_001300728.1; NM_001313799.1.
ProteinModelPortal; E2RAK7; -.
STRING; 9615.ENSCAFP00000018988; -.
PaxDb; E2RAK7; -.
PRIDE; E2RAK7; -.
Ensembl; ENSCAFT00000020461; ENSCAFP00000018988; ENSCAFG00000012886.
GeneID; 478982; -.
KEGG; cfa:478982; -.
CTD; 336; -.
VGNC; VGNC:37992; APOA2.
eggNOG; ENOG410J3V8; Eukaryota.
eggNOG; ENOG4111552; LUCA.
GeneTree; ENSGT00390000003306; -.
InParanoid; E2RAK7; -.
KO; K08758; -.
OMA; AYFEKTQ; -.
OrthoDB; EOG091G0Z27; -.
TreeFam; TF338165; -.
Reactome; R-CFA-381426; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs).
Reactome; R-CFA-8957275; Post-translational protein phosphorylation.
Reactome; R-CFA-8963888; Chylomicron assembly.
Reactome; R-CFA-8963901; Chylomicron remodeling.
Reactome; R-CFA-975634; Retinoid metabolism and transport.
Proteomes; UP000002254; Chromosome 38.
Bgee; ENSCAFG00000012886; -.
GO; GO:0072562; C:blood microparticle; IBA:GO_Central.
GO; GO:0042627; C:chylomicron; IBA:GO_Central.
GO; GO:0034366; C:spherical high-density lipoprotein particle; IBA:GO_Central.
GO; GO:0034361; C:very-low-density lipoprotein particle; IBA:GO_Central.
GO; GO:0034190; F:apolipoprotein receptor binding; IBA:GO_Central.
GO; GO:0015485; F:cholesterol binding; IBA:GO_Central.
GO; GO:0017127; F:cholesterol transporter activity; IEA:Ensembl.
GO; GO:0031072; F:heat shock protein binding; IEA:Ensembl.
GO; GO:0008035; F:high-density lipoprotein particle binding; IBA:GO_Central.
GO; GO:0070653; F:high-density lipoprotein particle receptor binding; IBA:GO_Central.
GO; GO:0055102; F:lipase inhibitor activity; IBA:GO_Central.
GO; GO:0031210; F:phosphatidylcholine binding; IBA:GO_Central.
GO; GO:0060228; F:phosphatidylcholine-sterol O-acyltransferase activator activity; IEA:Ensembl.
GO; GO:0046982; F:protein heterodimerization activity; IEA:Ensembl.
GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
GO; GO:0033344; P:cholesterol efflux; IEA:Ensembl.
GO; GO:0042632; P:cholesterol homeostasis; IBA:GO_Central.
GO; GO:0008203; P:cholesterol metabolic process; IBA:GO_Central.
GO; GO:0046340; P:diacylglycerol catabolic process; IEA:Ensembl.
GO; GO:0034380; P:high-density lipoprotein particle assembly; IBA:GO_Central.
GO; GO:0034384; P:high-density lipoprotein particle clearance; IEA:Ensembl.
GO; GO:0034375; P:high-density lipoprotein particle remodeling; IBA:GO_Central.
GO; GO:0042157; P:lipoprotein metabolic process; IBA:GO_Central.
GO; GO:0034374; P:low-density lipoprotein particle remodeling; IBA:GO_Central.
GO; GO:0060621; P:negative regulation of cholesterol import; IEA:Ensembl.
GO; GO:0060695; P:negative regulation of cholesterol transporter activity; IEA:Ensembl.
GO; GO:0002740; P:negative regulation of cytokine secretion involved in immune response; IEA:Ensembl.
GO; GO:0060192; P:negative regulation of lipase activity; IBA:GO_Central.
GO; GO:0050995; P:negative regulation of lipid catabolic process; IEA:Ensembl.
GO; GO:0010903; P:negative regulation of very-low-density lipoprotein particle remodeling; IEA:Ensembl.
GO; GO:0018206; P:peptidyl-methionine modification; IEA:Ensembl.
GO; GO:0006656; P:phosphatidylcholine biosynthetic process; IEA:Ensembl.
GO; GO:0009395; P:phospholipid catabolic process; IEA:Ensembl.
GO; GO:0033700; P:phospholipid efflux; IEA:Ensembl.
GO; GO:0010873; P:positive regulation of cholesterol esterification; IEA:Ensembl.
GO; GO:0045416; P:positive regulation of interleukin-8 biosynthetic process; IEA:Ensembl.
GO; GO:0050996; P:positive regulation of lipid catabolic process; IEA:Ensembl.
GO; GO:0018158; P:protein oxidation; IEA:Ensembl.
GO; GO:0030300; P:regulation of intestinal cholesterol absorption; IEA:Ensembl.
GO; GO:0031647; P:regulation of protein stability; IEA:Ensembl.
GO; GO:0009749; P:response to glucose; IEA:Ensembl.
GO; GO:0043691; P:reverse cholesterol transport; IEA:Ensembl.
GO; GO:0034370; P:triglyceride-rich lipoprotein particle remodeling; IBA:GO_Central.
InterPro; IPR006801; ApoA-II.
InterPro; IPR036172; ApoA-II_sf.
PANTHER; PTHR11027; PTHR11027; 1.
Pfam; PF04711; ApoA-II; 1.
ProDom; PD010397; ApoA-II; 1.
SUPFAM; SSF82936; SSF82936; 1.
1: Evidence at protein level;
Cleavage on pair of basic residues; Complete proteome;
Direct protein sequencing; HDL; Lipid transport; Oxidation;
Reference proteome; Secreted; Signal; Transport.
SIGNAL 1 18 {ECO:0000255}.
CHAIN 19 100 Proapolipoprotein A-II.
/FTId=PRO_0000425726.
CHAIN 24 100 Apolipoprotein A-II.
{ECO:0000305|PubMed:20483223}.
/FTId=PRO_0000425727.
CHAIN 24 99 Truncated apolipoprotein A-II.
{ECO:0000250|UniProtKB:P02652}.
/FTId=PRO_0000425728.
MOD_RES 49 49 Methionine sulfoxide.
{ECO:0000250|UniProtKB:P02652}.
SEQUENCE 100 AA; 11225 MW; DBA661E8FDFAE188 CRC64;
MKLLAVTVLL LVICSLEGAF VRRQAEEPNL QSLVSQYFQT VTDYGKDLME KAKGPELQAQ
AKAYFEKTQE QLTPLVKKAG TDLLNFLSNF MDLKTQPATQ


Related products :

Catalog number Product name Quantity
E0604Rb ELISA APOA1,Apo-AI,ApoA-I,Apolipoprotein A1,Apolipoprotein A-I,Oryctolagus cuniculus,Rabbit 96T
E0604h ELISA APOA1,Apo-AI,ApoA-I,Apolipoprotein A1,Apolipoprotein A-I,Homo sapiens,Human 96T
U0604h CLIA APOA1,Apo-AI,ApoA-I,Apolipoprotein A1,Apolipoprotein A-I,Homo sapiens,Human 96T
E0604h ELISA kit APOA1,Apo-AI,ApoA-I,Apolipoprotein A1,Apolipoprotein A-I,Homo sapiens,Human 96T
U0604Rb CLIA APOA1,Apo-AI,ApoA-I,Apolipoprotein A1,Apolipoprotein A-I,Oryctolagus cuniculus,Rabbit 96T
E0604Rb ELISA kit APOA1,Apo-AI,ApoA-I,Apolipoprotein A1,Apolipoprotein A-I,Oryctolagus cuniculus,Rabbit 96T
E0604m ELISA kit Apoa1,Apo-AI,ApoA-I,Apolipoprotein A1,Apolipoprotein A-I,Mouse,Mus musculus 96T
E0604b ELISA kit APOA1,Apo-AI,ApoA-I,Apolipoprotein A1,Apolipoprotein A-I,Bos taurus,Bovine 96T
U0604b CLIA APOA1,Apo-AI,ApoA-I,Apolipoprotein A1,Apolipoprotein A-I,Bos taurus,Bovine 96T
E0604r ELISA Apoa1,Apo-AI,ApoA-I,Apolipoprotein A1,Apolipoprotein A-I,Rat,Rattus norvegicus 96T
E0604r ELISA kit Apoa1,Apo-AI,ApoA-I,Apolipoprotein A1,Apolipoprotein A-I,Rat,Rattus norvegicus 96T
U0604r CLIA Apoa1,Apo-AI,ApoA-I,Apolipoprotein A1,Apolipoprotein A-I,Rat,Rattus norvegicus 96T
E0604m ELISA Apoa1,Apo-AI,ApoA-I,Apolipoprotein A1,Apolipoprotein A-I,Mouse,Mus musculus 96T
U0604m CLIA Apoa1,Apo-AI,ApoA-I,Apolipoprotein A1,Apolipoprotein A-I,Mouse,Mus musculus 96T
E0604b ELISA APOA1,Apo-AI,ApoA-I,Apolipoprotein A1,Apolipoprotein A-I,Bos taurus,Bovine 96T
E0604p ELISA APOA1,Apo-AI,ApoA-I,Apolipoprotein A1,Apolipoprotein A-I,Pig,Sus scrofa 96T
E0604p ELISA kit APOA1,Apo-AI,ApoA-I,Apolipoprotein A1,Apolipoprotein A-I,Pig,Sus scrofa 96T
U0604p CLIA APOA1,Apo-AI,ApoA-I,Apolipoprotein A1,Apolipoprotein A-I,Pig,Sus scrofa 96T
E0604c ELISA APOA1,Apo-AI,ApoA-I,Apolipoprotein A1,Apolipoprotein A-I,Chicken,Gallus gallus 96T
U0604c CLIA APOA1,Apo-AI,ApoA-I,Apolipoprotein A1,Apolipoprotein A-I,Chicken,Gallus gallus 96T
E0604c ELISA kit APOA1,Apo-AI,ApoA-I,Apolipoprotein A1,Apolipoprotein A-I,Chicken,Gallus gallus 96T
20-272-192023 Apolipoprotein J - Mouse monoclonal [Hs - 3] to Apolipoprotein J; Complement-associated protein SP-40.40; Complement cytolysis inhibitor; CLI; NA1_NA2; Apolipoprotein J; Apo-J; Testosterone-repressed 0.05 mg
E0604c ELISA APOA1,Apo-AI,ApoA-I,Apolipoprotein A1,Apolipoprotein A-I,Canis familiaris,Canis lupus familiaris,Dog 96T
E0604c ELISA kit APOA1,Apo-AI,ApoA-I,Apolipoprotein A1,Apolipoprotein A-I,Canis familiaris,Canis lupus familiaris,Dog 96T
U0604c CLIA APOA1,Apo-AI,ApoA-I,Apolipoprotein A1,Apolipoprotein A-I,Canis familiaris,Canis lupus familiaris,Dog 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur