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Aquaporin 1 (Colton blood group)

 M3X1K6_FELCA            Unreviewed;       271 AA.
M3X1K6;
01-MAY-2013, integrated into UniProtKB/TrEMBL.
01-MAY-2013, sequence version 1.
28-MAR-2018, entry version 41.
SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSFCAP00000020501};
Name=AQP1 {ECO:0000313|Ensembl:ENSFCAP00000020501};
Felis catus (Cat) (Felis silvestris catus).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;
Felinae; Felis.
NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000020501, ECO:0000313|Proteomes:UP000011712};
[1] {ECO:0000313|Ensembl:ENSFCAP00000020501, ECO:0000313|Proteomes:UP000011712}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000020501,
ECO:0000313|Proteomes:UP000011712};
PubMed=17975172; DOI=10.1101/gr.6380007;
Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N.,
Schaffer A.A., Agarwala R., Narfstrom K., Murphy W.J., Giger U.,
Roca A.L., Antunes A., Menotti-Raymond M., Yuhki N.,
Pecon-Slattery J., Johnson W.E., Bourque G., Tesler G., O'Brien S.J.;
"Initial sequence and comparative analysis of the cat genome.";
Genome Res. 17:1675-1689(2007).
[2] {ECO:0000313|Ensembl:ENSFCAP00000020501}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000020501};
Hillier L.W., Warren W., Obrien S., Wilson R.K.;
"Sequence assembly of the Felis catus genome version 6.2.";
Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
[3] {ECO:0000313|Ensembl:ENSFCAP00000020501}
IDENTIFICATION.
STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000020501};
Ensembl;
Submitted (MAR-2013) to UniProtKB.
-!- SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family.
{ECO:0000256|RuleBase:RU000477, ECO:0000256|SAAS:SAAS00692148}.
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EMBL; AANG03322413; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AANG03322414; -; NOT_ANNOTATED_CDS; Genomic_DNA.
RefSeq; XP_003982956.1; XM_003982907.4.
STRING; 9685.ENSFCAP00000020501; -.
Ensembl; ENSFCAT00000028631; ENSFCAP00000020501; ENSFCAG00000027043.
GeneID; 101087725; -.
KEGG; fca:101087725; -.
CTD; 358; -.
eggNOG; KOG0223; Eukaryota.
eggNOG; COG0580; LUCA.
GeneTree; ENSGT00760000119223; -.
InParanoid; M3X1K6; -.
KO; K09864; -.
OMA; ELFGTFW; -.
OrthoDB; EOG091G166T; -.
Proteomes; UP000011712; Chromosome A2.
Bgee; ENSFCAG00000027043; -.
GO; GO:0016323; C:basolateral plasma membrane; IBA:GO_Central.
GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
GO; GO:0008519; F:ammonium transmembrane transporter activity; IBA:GO_Central.
GO; GO:0035379; F:carbon dioxide transmembrane transporter activity; IBA:GO_Central.
GO; GO:0015250; F:water channel activity; IBA:GO_Central.
GO; GO:0072488; P:ammonium transmembrane transport; IBA:GO_Central.
CDD; cd00333; MIP; 1.
Gene3D; 1.20.1080.10; -; 1.
InterPro; IPR023271; Aquaporin-like.
InterPro; IPR023274; Aquaporin_1.
InterPro; IPR034294; Aquaporin_transptr.
InterPro; IPR000425; MIP.
InterPro; IPR022357; MIP_CS.
PANTHER; PTHR19139; PTHR19139; 1.
Pfam; PF00230; MIP; 1.
PRINTS; PR02013; AQUAPORIN1.
PRINTS; PR00783; MINTRINSICP.
SUPFAM; SSF81338; SSF81338; 1.
TIGRFAMs; TIGR00861; MIP; 1.
PROSITE; PS00221; MIP; 1.
3: Inferred from homology;
Complete proteome {ECO:0000313|Proteomes:UP000011712};
Membrane {ECO:0000256|SAAS:SAAS00692112, ECO:0000256|SAM:Phobius};
Reference proteome {ECO:0000313|Proteomes:UP000011712};
Transmembrane {ECO:0000256|SAAS:SAAS00692112,
ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAAS:SAAS00692112,
ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000477}.
TRANSMEM 9 35 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 55 75 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 96 121 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 141 159 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 166 186 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 212 233 Helical. {ECO:0000256|SAM:Phobius}.
SEQUENCE 271 AA; 28784 MW; 39431A8B8EA25608 CRC64;
MASEFKKKLF WRAVVAEFLA MTLFVFISIG SALGFHYPVK NNQTAGASQD NVKVSLAFGL
SIATLAQSVG HISGAHLNPA VTLGLLLSCQ ISILRAIMYI IAQCVGAIVA TAILSGVTSS
LPDNSLGRNE LAPGVNSGQG LGIEIIGTLQ LVLCVLATTD RRRRDLGGSG PLAIGLSVAL
GHLLAIDYTG CGINPARSFG SSVITHNFKD HWIFWVGPFI GGALAVLIYD FILAPRSSDL
TDRVKVWTSG QVEEYDLDGD DINSRVEMKP K


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