Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Arabinose operon regulatory protein

 ARAC_ECOLI              Reviewed;         292 AA.
P0A9E0; P03021; Q47056;
21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
21-JUL-1986, sequence version 1.
12-SEP-2018, entry version 114.
RecName: Full=Arabinose operon regulatory protein;
Name=araC; OrderedLocusNames=b0064, JW0063;
Escherichia coli (strain K12).
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
Enterobacteriaceae; Escherichia.
NCBI_TaxID=83333;
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=B/R;
PubMed=7019009; DOI=10.1016/0378-1119(80)90100-6;
Wallace R.G., Lee N., Fowler A.V.;
"The araC gene of Escherichia coli: transcriptional and translational
start-points and complete nucleotide sequence.";
Gene 12:179-190(1980).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=B/R;
PubMed=7008027; DOI=10.1093/nar/8.22.5267;
Miyada C.G., Horwitz A.H., Cass L.G., Timko J., Wilcox G.;
"DNA sequence of the araC regulatory gene from Escherichia coli B/r.";
Nucleic Acids Res. 8:5267-5274(1980).
[3]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=K12;
PubMed=6283093; DOI=10.1016/S0022-2836(82)80020-X;
Stoner C.M., Schleif R.;
"Is the amino acid but not the nucleotide sequence of the Escherichia
coli araC gene conserved?";
J. Mol. Biol. 154:649-652(1982).
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=K12;
PubMed=1630901; DOI=10.1093/nar/20.13.3305;
Yura T., Mori H., Nagai H., Nagata T., Ishihama A., Fujita N.,
Isono K., Mizobuchi K., Nakata A.;
"Systematic sequencing of the Escherichia coli genome: analysis of the
0-2.4 min region.";
Nucleic Acids Res. 20:3305-3308(1992).
[5]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=K12 / MG1655 / ATCC 47076;
PubMed=9278503; DOI=10.1126/science.277.5331.1453;
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J.,
Mau B., Shao Y.;
"The complete genome sequence of Escherichia coli K-12.";
Science 277:1453-1462(1997).
[6]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
PubMed=16738553; DOI=10.1038/msb4100049;
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
"Highly accurate genome sequences of Escherichia coli K-12 strains
MG1655 and W3110.";
Mol. Syst. Biol. 2:E1-E5(2006).
[7]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-61.
STRAIN=B/R;
PubMed=6160371; DOI=10.1007/BF00267373;
Cass L.G., Horwitz A.H., Miyada C.G., Greenfield L., Wilcox G.;
"The araC regulatory gene mRNA contains a leader sequence.";
Mol. Gen. Genet. 180:219-226(1980).
[8]
IDENTIFICATION BY 2D-GEL.
PubMed=9298644; DOI=10.1002/elps.1150180805;
VanBogelen R.A., Abshire K.Z., Moldover B., Olson E.R.,
Neidhardt F.C.;
"Escherichia coli proteome analysis using the gene-protein database.";
Electrophoresis 18:1243-1251(1997).
[9]
X-RAY CRYSTALLOGRAPHY (1.6 ANGSTROMS) OF 1-178.
PubMed=9367758; DOI=10.1006/jmbi.1997.1314;
Soisson S.M., Macdougall-Shackleton B., Schleif R., Wolberger C.;
"The 1.6 A crystal structure of the AraC sugar-binding and
dimerization domain complexed with D-fucose.";
J. Mol. Biol. 273:226-237(1997).
[10]
X-RAY CRYSTALLOGRAPHY (1.5 AND 2.8 ANGSTROMS).
PubMed=9103202; DOI=10.1126/science.276.5311.421;
Soisson S.M., Macdougall-Shackleton B., Schleif R., Wolberger C.;
"Structural basis for ligand-regulated oligomerization of AraC.";
Science 276:421-425(1997).
-!- FUNCTION: This protein controls the expression of at least six
genes that are involved in the transport and catabolism of L-
arabinose. It regulates initiation of transcription of the araBAD
operon and it also controls its own synthesis. The L-arabinose
operon displays both positive and negative regulation through
AraC.
-!- SUBUNIT: Homodimer.
-!- INTERACTION:
Self; NbExp=3; IntAct=EBI-1113479, EBI-1113479;
P0A8P6:xerC; NbExp=3; IntAct=EBI-1113479, EBI-1133806;
-!- SUBCELLULAR LOCATION: Cytoplasm.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; V00256; CAA23507.1; -; Genomic_DNA.
EMBL; V00259; CAA23508.1; -; Genomic_DNA.
EMBL; J01641; AAA23466.1; -; Genomic_DNA.
EMBL; U00096; AAC73175.1; -; Genomic_DNA.
EMBL; AP009048; BAB96633.1; -; Genomic_DNA.
EMBL; K01303; AAA23468.1; -; Genomic_DNA.
PIR; A91473; RGECA.
RefSeq; NP_414606.1; NC_000913.3.
RefSeq; WP_001300811.1; NZ_LN832404.1.
PDB; 1XJA; X-ray; 2.40 A; A/B/C/D/E=1-178.
PDB; 2AAC; X-ray; 1.60 A; A/B=2-178.
PDB; 2ARA; X-ray; 2.80 A; A=19-167.
PDB; 2ARC; X-ray; 1.50 A; A/B=7-170.
PDB; 2K9S; NMR; -; A=175-281.
PDBsum; 1XJA; -.
PDBsum; 2AAC; -.
PDBsum; 2ARA; -.
PDBsum; 2ARC; -.
PDBsum; 2K9S; -.
ProteinModelPortal; P0A9E0; -.
SMR; P0A9E0; -.
BioGrid; 4260828; 116.
DIP; DIP-9125N; -.
IntAct; P0A9E0; 12.
STRING; 316407.21321946; -.
DrugBank; DB03142; Alpha-L-Arabinose.
DrugBank; DB04062; Beta-D-Fucose.
PaxDb; P0A9E0; -.
PRIDE; P0A9E0; -.
EnsemblBacteria; AAC73175; AAC73175; b0064.
EnsemblBacteria; BAB96633; BAB96633; BAB96633.
GeneID; 944780; -.
KEGG; ecj:JW0063; -.
KEGG; eco:b0064; -.
PATRIC; fig|511145.12.peg.66; -.
EchoBASE; EB0052; -.
EcoGene; EG10054; araC.
eggNOG; ENOG41063TF; Bacteria.
eggNOG; ENOG4111G16; LUCA.
HOGENOM; HOG000276603; -.
InParanoid; P0A9E0; -.
KO; K02099; -.
OMA; GFEDQLY; -.
PhylomeDB; P0A9E0; -.
BioCyc; EcoCyc:PD00242; -.
EvolutionaryTrace; P0A9E0; -.
PRO; PR:P0A9E0; -.
Proteomes; UP000000318; Chromosome.
Proteomes; UP000000625; Chromosome.
CollecTF; EXPREG_000007d0; -.
GO; GO:0005829; C:cytosol; IDA:EcoCyc.
GO; GO:0032993; C:protein-DNA complex; IDA:CollecTF.
GO; GO:0001216; F:bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding; IDA:CollecTF.
GO; GO:0001217; F:bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding; IDA:CollecTF.
GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
GO; GO:0042802; F:identical protein binding; IPI:IntAct.
GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IDA:CollecTF.
GO; GO:0019568; P:arabinose catabolic process; IMP:EcoliWiki.
GO; GO:0019249; P:lactate biosynthetic process; IEA:GOC.
GO; GO:0061727; P:methylglyoxal catabolic process to lactate; IEA:GOC.
GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
InterPro; IPR003313; AraC-bd.
InterPro; IPR009057; Homeobox-like_sf.
InterPro; IPR037923; HTH-like.
InterPro; IPR018060; HTH_AraC.
InterPro; IPR018062; HTH_AraC-typ_CS.
InterPro; IPR020449; Tscrpt_reg_HTH_AraC-type.
Pfam; PF02311; AraC_binding; 1.
Pfam; PF12833; HTH_18; 1.
PRINTS; PR00032; HTHARAC.
SMART; SM00342; HTH_ARAC; 1.
SUPFAM; SSF46689; SSF46689; 2.
SUPFAM; SSF51215; SSF51215; 1.
PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
1: Evidence at protein level;
3D-structure; Activator; Arabinose catabolism;
Carbohydrate metabolism; Complete proteome; Cytoplasm; DNA-binding;
Reference proteome; Repressor; Transcription;
Transcription regulation.
CHAIN 1 292 Arabinose operon regulatory protein.
/FTId=PRO_0000194499.
DNA_BIND 197 216 H-T-H motif. {ECO:0000255|PROSITE-
ProRule:PRU00593}.
REGION 1 ? Dimerization.
CONFLICT 7 7 D -> E (in Ref. 7; AAA23468).
{ECO:0000305}.
TURN 11 13 {ECO:0000244|PDB:1XJA}.
STRAND 16 18 {ECO:0000244|PDB:2ARC}.
STRAND 20 27 {ECO:0000244|PDB:2ARC}.
STRAND 36 38 {ECO:0000244|PDB:2ARC}.
STRAND 43 53 {ECO:0000244|PDB:2ARC}.
STRAND 55 59 {ECO:0000244|PDB:2ARC}.
STRAND 62 66 {ECO:0000244|PDB:2ARC}.
STRAND 71 74 {ECO:0000244|PDB:2ARC}.
STRAND 80 84 {ECO:0000244|PDB:2ARC}.
STRAND 88 98 {ECO:0000244|PDB:2ARC}.
HELIX 102 107 {ECO:0000244|PDB:2ARC}.
STRAND 112 114 {ECO:0000244|PDB:2ARC}.
STRAND 117 120 {ECO:0000244|PDB:2ARC}.
TURN 124 126 {ECO:0000244|PDB:2ARC}.
HELIX 127 142 {ECO:0000244|PDB:2ARC}.
STRAND 145 147 {ECO:0000244|PDB:2ARC}.
HELIX 148 166 {ECO:0000244|PDB:2ARC}.
HELIX 177 188 {ECO:0000244|PDB:2K9S}.
HELIX 197 203 {ECO:0000244|PDB:2K9S}.
HELIX 208 219 {ECO:0000244|PDB:2K9S}.
HELIX 223 241 {ECO:0000244|PDB:2K9S}.
HELIX 246 252 {ECO:0000244|PDB:2K9S}.
HELIX 258 269 {ECO:0000244|PDB:2K9S}.
HELIX 273 278 {ECO:0000244|PDB:2K9S}.
SEQUENCE 292 AA; 33384 MW; C5A737E285A4ECC6 CRC64;
MAEAQNDPLL PGYSFNAHLV AGLTPIEANG YLDFFIDRPL GMKGYILNLT IRGQGVVKNQ
GREFVCRPGD ILLFPPGEIH HYGRHPEARE WYHQWVYFRP RAYWHEWLNW PSIFANTGFF
RPDEAHQPHF SDLFGQIINA GQGEGRYSEL LAINLLEQLL LRRMEAINES LHPPMDNRVR
EACQYISDHL ADSNFDIASV AQHVCLSPSR LSHLFRQQLG ISVLSWREDQ RISQAKLLLS
TTRMPIATVG RNVGFDDQLY FSRVFKKCTG ASPSEFRAGC EEKVNDVAVK LS


Related products :

Catalog number Product name Quantity
A023706 Rabbit Anti-F1 operon positive regulatory protein(NT) Ab 100ul
A023707 Rabbit Anti-F1 operon positive regulatory protein(CT) Ab 100ul
bs-0950P Peptides: F1 operon positive regulatory protein(CT) Protein Length:12-25 amino acids. 200ug lyophilized
bs-0949P Peptides: F1 operon positive regulatory protein(NT) Protein Length:12-25 amino acids. 200ug lyophilized
orb86121 F1 operon positive regulatory protein (NT) protein Proteins 0.5 mg
orb86120 F1 operon positive regulatory protein (CT) protein Proteins 0.5 mg
bs-0950R Rabbit Anti-F1 operon positive regulatory protein Polyclonal Antibody 100ul
bs-0950R Rabbit Anti-F1 operon positive regulatory protein Polyclonal Antibody 100ug Lyophilized
bs-0949R Rabbit Anti-F1 operon positive regulatory protein(NT) Polyclonal Antibody 100ug Lyophilized
bs-0949R-PE Rabbit Anti-F1 operon positive regulatory protein(NT) Polyclonal Antibody, PE Conjugated 100ug
bs-0949R-Cy3 Rabbit Anti-F1 operon positive regulatory protein(NT) Polyclonal Antibody, Cy3 Conjugated 100ug
bs-0949R-PE-Cy3 Rabbit Anti-F1 operon positive regulatory protein(NT) Polyclonal Antibody, PE-Cy3 Conjugated 100ug
bs-0950R-PE-Cy3 Rabbit Anti-F1 operon positive regulatory protein(CT) Polyclonal Antibody, PE-Cy3 Conjugated 100ug
bs-0950R-A594 F1 operon positive regulatory protein Antibody, ALEXA FLUOR 594 Conjugated 100ul
bs-0949R-PE-Cy5 Rabbit Anti-F1 operon positive regulatory protein(NT) Polyclonal Antibody, PE-Cy5 Conjugated 100ug
bs-0950R-PE-Cy5 Rabbit Anti-F1 operon positive regulatory protein(CT) Polyclonal Antibody, PE-Cy5 Conjugated 100ug
bs-0949R Rabbit Anti-F1 operon positive regulatory protein(NT) Polyclonal Antibody, Unconjugated 100ug
bs-0950R-PE Rabbit Anti-F1 operon positive regulatory protein(CT) Polyclonal Antibody, PE Conjugated 100ug
bs-0950R Rabbit Anti-F1 operon positive regulatory protein(CT) Polyclonal Antibody, Unconjugated 100ug
bs-0949R-Cy5 Rabbit Anti-F1 operon positive regulatory protein(NT) Polyclonal Antibody, Cy5 Conjugated 100ug
bs-0950R-HRP Rabbit Anti-F1 operon positive regulatory protein Polyclonal Antibody, HRP Conjugated 100ul
bs-0950R-Cy3 Rabbit Anti-F1 operon positive regulatory protein(CT) Polyclonal Antibody, Cy3 Conjugated 100ug
bs-0950R-Cy5 Rabbit Anti-F1 operon positive regulatory protein Polyclonal Antibody, Cy5 Conjugated 100ul
bs-0950R-Cy3 Rabbit Anti-F1 operon positive regulatory protein Polyclonal Antibody, Cy3 Conjugated 100ul
bs-0949R-Cy7 Rabbit Anti-F1 operon positive regulatory protein(NT) Polyclonal Antibody, Cy7 Conjugated 100ug


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur