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Arsenical resistance operon repressor

 ARSR_STAXY              Reviewed;         104 AA.
Q01256;
01-APR-1993, integrated into UniProtKB/Swiss-Prot.
01-APR-1993, sequence version 1.
05-DEC-2018, entry version 77.
RecName: Full=Arsenical resistance operon repressor;
Name=arsR;
Staphylococcus xylosus.
Plasmid pSX267.
Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
Staphylococcus.
NCBI_TaxID=1288;
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=DSM 20267 / Isolate C2A;
PubMed=1534327; DOI=10.1128/jb.174.11.3676-3683.1992;
Rosenstein R., Peschel A., Wieland B., Goetz F.;
"Expression and regulation of the antimonite, arsenite, and arsenate
resistance operon of Staphylococcus xylosus plasmid pSX267.";
J. Bacteriol. 174:3676-3683(1992).
-!- FUNCTION: Transcriptional repressor for the ars operon. ArsR is a
trans-acting regulatory protein which controls its own expression.
The repressive effect of ArsR is alleviated by oxyions of +III
oxidation state of arsenic, antimony, and bismuth, as well as
arsenate (As(V)).
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EMBL; M80565; AAA27587.1; -; Genomic_DNA.
PIR; A41902; A41902.
ProteinModelPortal; Q01256; -.
SMR; Q01256; -.
GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
GO; GO:0046685; P:response to arsenic-containing substance; IEA:UniProtKB-KW.
CDD; cd00090; HTH_ARSR; 1.
Gene3D; 1.10.10.10; -; 1.
InterPro; IPR011991; ArsR-like_HTH.
InterPro; IPR018334; ArsR_HTH.
InterPro; IPR001845; HTH_ArsR_DNA-bd_dom.
InterPro; IPR036388; WH-like_DNA-bd_sf.
InterPro; IPR036390; WH_DNA-bd_sf.
Pfam; PF01022; HTH_5; 1.
PRINTS; PR00778; HTHARSR.
SMART; SM00418; HTH_ARSR; 1.
SUPFAM; SSF46785; SSF46785; 1.
PROSITE; PS00846; HTH_ARSR_1; 1.
PROSITE; PS50987; HTH_ARSR_2; 1.
4: Predicted;
Arsenical resistance; DNA-binding; Plasmid; Repressor; Transcription;
Transcription regulation.
CHAIN 1 104 Arsenical resistance operon repressor.
/FTId=PRO_0000160615.
DOMAIN 1 92 HTH arsR-type. {ECO:0000255|PROSITE-
ProRule:PRU00340}.
DNA_BIND 32 51 H-T-H motif. {ECO:0000255|PROSITE-
ProRule:PRU00340}.
SEQUENCE 104 AA; 11866 MW; 17B68444B7B344A7 CRC64;
MSYKELSTIL KVLSDPSRLE ILDLLSCGEL CACDLLEHFQ FSQPTLSHHM KSLVDNELVT
TRKNGNKHMY QLNHEFLDYI NQNLDIINTS DQGCACKNMK SGEC


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