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Auxin-induced protein 22A (Indole-3-acetic acid-induced protein ARG3)

 AX22A_VIGRR             Reviewed;         194 AA.
P32293;
01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
01-OCT-1993, sequence version 1.
07-JUN-2017, entry version 65.
RecName: Full=Auxin-induced protein 22A;
AltName: Full=Indole-3-acetic acid-induced protein ARG3;
Name=AUX22A; Synonyms=ARG3;
Vigna radiata var. radiata (Mung bean) (Phaseolus aureus).
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae;
Phaseoleae; Vigna.
NCBI_TaxID=3916;
[1]
NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Hypocotyl;
Yamamoto K.T., Mori H., Imaseki H.;
"cDNA cloning of indole-3-acetic acid regulated genes: Aux22 and SAUR
from mung bean (Vigna radiata) hypocotyl tissue.";
Plant Cell Physiol. 33:93-97(1992).
-!- FUNCTION: Aux/IAA proteins are short-lived transcriptional factors
that function as repressors of early auxin response genes at low
auxin concentrations. Repression is thought to result from the
interaction with auxin response factors (ARFs), proteins that bind
to the auxin-responsive promoter element (AuxRE). Formation of
heterodimers with ARF proteins may alter their ability to modulate
early auxin response genes expression (By similarity).
{ECO:0000250}.
-!- SUBUNIT: Homodimers and heterodimers. {ECO:0000250}.
-!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
-!- DEVELOPMENTAL STAGE: Found in elongating hypocotyls.
-!- INDUCTION: By auxin and cycloheximide.
-!- DOMAIN: The N-terminal half of the protein contains two conserved
domains I and II. Domain I includes a slightly degenerated ERF-
associated amphiphilic repression (EAR) motif which seems to be
involved in the activity of transcriptional repression. Domain II
is required for the correct degradation of the protein through the
SCF-mediated ubiquitin-proteasome pathway. Interactions between
Aux/IAA proteins and auxin response factors (ARFs) occur through
their C-terminal dimerization domains III and IV (By similarity).
{ECO:0000250}.
-!- SIMILARITY: Belongs to the Aux/IAA family. {ECO:0000305}.
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EMBL; D14412; BAA03308.1; -; mRNA.
PIR; T10939; T10939.
SMR; P32293; -.
Proteomes; UP000087766; Genome assembly.
GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-KW.
GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
InterPro; IPR033389; AUX/IAA_dom.
InterPro; IPR003311; AUX_IAA.
InterPro; IPR000270; PB1_dom.
PANTHER; PTHR31734; PTHR31734; 1.
Pfam; PF02309; AUX_IAA; 1.
PROSITE; PS51745; PB1; 1.
2: Evidence at transcript level;
Auxin signaling pathway; Complete proteome; Nucleus;
Reference proteome; Repressor; Transcription;
Transcription regulation.
CHAIN 1 194 Auxin-induced protein 22A.
/FTId=PRO_0000112863.
DOMAIN 85 173 PB1. {ECO:0000255|PROSITE-
ProRule:PRU01081}.
MOTIF 13 17 EAR-like (transcriptional repression).
SEQUENCE 194 AA; 21514 MW; B8E3BC6D925FC88C CRC64;
MAKEGLGLEI TELRLGLPDA EHVAVANKNG EKKNKRVFSE IDDVGDENSS SGGGGDRKME
NKNQVVGWPP VCSYRKKNSV NEASKMYVKV SMDGAPFLRK MDLGMHKGYS DLAFALEKLF
GCYGMVEALK NVENGEHVPI YEDKDGDWML VGDVPWEMFM ESCKRLRIMK RADAKGFGLQ
PKGSLKGFIE SVGK


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