Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Axin 1 (Axin-1-like isoform 2)

 E1B714_BOVIN            Unreviewed;       830 AA.
E1B714;
02-NOV-2010, integrated into UniProtKB/TrEMBL.
16-NOV-2011, sequence version 2.
20-JUN-2018, entry version 64.
SubName: Full=Axin 1 {ECO:0000313|Ensembl:ENSBTAP00000022053};
SubName: Full=Axin-1-like isoform 2 {ECO:0000313|EMBL:DAA15676.1};
Name=AXIN1 {ECO:0000313|EMBL:DAA15676.1,
ECO:0000313|Ensembl:ENSBTAP00000022053, ECO:0000313|VGNC:VGNC:26364};
ORFNames=BOS_22580 {ECO:0000313|EMBL:DAA15676.1};
Bos taurus (Bovine).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
Pecora; Bovidae; Bovinae; Bos.
NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000022053, ECO:0000313|Proteomes:UP000009136};
[1] {ECO:0000313|EMBL:DAA15676.1, ECO:0000313|Ensembl:ENSBTAP00000022053, ECO:0000313|Proteomes:UP000009136}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000022053,
ECO:0000313|Proteomes:UP000009136};
PubMed=19393038; DOI=10.1186/gb-2009-10-4-r42;
Zimin A.V., Delcher A.L., Florea L., Kelley D.R., Schatz M.C.,
Puiu D., Hanrahan F., Pertea G., Van Tassell C.P., Sonstegard T.S.,
Marcais G., Roberts M., Subramanian P., Yorke J.A., Salzberg S.L.;
"A whole-genome assembly of the domestic cow, Bos taurus.";
Genome Biol. 10:R42.01-R42.10(2009).
[2] {ECO:0000313|Ensembl:ENSBTAP00000022053}
IDENTIFICATION.
STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000022053};
Ensembl;
Submitted (MAR-2016) to UniProtKB.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; DAAA02057275; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; GJ062847; DAA15676.1; -; Genomic_DNA.
RefSeq; NP_001178327.1; NM_001191398.1.
UniGene; Bt.21602; -.
STRING; 9913.ENSBTAP00000022053; -.
Ensembl; ENSBTAT00000022053; ENSBTAP00000022053; ENSBTAG00000016577.
GeneID; 504357; -.
KEGG; bta:504357; -.
CTD; 8312; -.
VGNC; VGNC:26364; AXIN1.
eggNOG; KOG3589; Eukaryota.
eggNOG; ENOG410YMJD; LUCA.
GeneTree; ENSGT00390000010011; -.
KO; K02157; -.
OMA; IMQWIIE; -.
OrthoDB; EOG091G0ABG; -.
TreeFam; TF315454; -.
Reactome; R-BTA-195253; Degradation of beta-catenin by the destruction complex.
Reactome; R-BTA-196299; Beta-catenin phosphorylation cascade.
Reactome; R-BTA-201681; TCF dependent signaling in response to WNT.
Reactome; R-BTA-4641257; Degradation of AXIN.
Reactome; R-BTA-4641262; Disassembly of the destruction complex and recruitment of AXIN to the membrane.
Reactome; R-BTA-5689880; Ub-specific processing proteases.
Proteomes; UP000009136; Chromosome 25.
Bgee; ENSBTAG00000016577; -.
GO; GO:0030877; C:beta-catenin destruction complex; IEA:Ensembl.
GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
GO; GO:0016328; C:lateral plasma membrane; IEA:Ensembl.
GO; GO:0005634; C:nucleus; IEA:Ensembl.
GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl.
GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
GO; GO:0008013; F:beta-catenin binding; IEA:Ensembl.
GO; GO:0005096; F:GTPase activator activity; IBA:GO_Central.
GO; GO:0070411; F:I-SMAD binding; IEA:Ensembl.
GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
GO; GO:0030159; F:receptor signaling complex scaffold activity; IEA:InterPro.
GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:Ensembl.
GO; GO:0007257; P:activation of JUN kinase activity; IBA:GO_Central.
GO; GO:0048320; P:axial mesoderm formation; IBA:GO_Central.
GO; GO:0060823; P:canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation; IBA:GO_Central.
GO; GO:0034622; P:cellular protein-containing complex assembly; IEA:Ensembl.
GO; GO:0031122; P:cytoplasmic microtubule organization; IBA:GO_Central.
GO; GO:0007368; P:determination of left/right symmetry; IBA:GO_Central.
GO; GO:0048048; P:embryonic eye morphogenesis; IBA:GO_Central.
GO; GO:0060272; P:embryonic skeletal joint morphogenesis; IBA:GO_Central.
GO; GO:0021797; P:forebrain anterior/posterior pattern specification; IBA:GO_Central.
GO; GO:0055001; P:muscle cell development; IBA:GO_Central.
GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:Ensembl.
GO; GO:0045599; P:negative regulation of fat cell differentiation; IBA:GO_Central.
GO; GO:0034244; P:negative regulation of transcription elongation from RNA polymerase II promoter; IBA:GO_Central.
GO; GO:0030910; P:olfactory placode formation; IBA:GO_Central.
GO; GO:0001743; P:optic placode formation; IBA:GO_Central.
GO; GO:0045732; P:positive regulation of protein catabolic process; IEA:Ensembl.
GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
GO; GO:0051443; P:positive regulation of ubiquitin-protein transferase activity; IEA:Ensembl.
GO; GO:0021881; P:Wnt-activated signaling pathway involved in forebrain neuron fate commitment; IBA:GO_Central.
CDD; cd11582; Axin_TNKS_binding; 1.
Gene3D; 1.10.196.10; -; 2.
Gene3D; 3.10.20.380; -; 1.
InterPro; IPR029797; AXIN1.
InterPro; IPR014936; Axin_b-cat-bd.
InterPro; IPR032101; Axin_TNKS-bd.
InterPro; IPR001158; DIX.
InterPro; IPR038207; DIX_dom_sf.
InterPro; IPR016137; RGS.
InterPro; IPR036305; RGS_sf.
InterPro; IPR024066; RGS_subdom1/3.
InterPro; IPR029071; Ubiquitin-like_domsf.
PANTHER; PTHR10845:SF11; PTHR10845:SF11; 1.
Pfam; PF16646; AXIN1_TNKS_BD; 1.
Pfam; PF08833; Axin_b-cat_bind; 1.
Pfam; PF00778; DIX; 1.
Pfam; PF00615; RGS; 1.
PRINTS; PR01301; RGSPROTEIN.
SMART; SM00021; DAX; 1.
SMART; SM00315; RGS; 1.
SUPFAM; SSF48097; SSF48097; 1.
SUPFAM; SSF54236; SSF54236; 1.
PROSITE; PS50841; DIX; 1.
PROSITE; PS50132; RGS; 1.
4: Predicted;
Coiled coil {ECO:0000256|SAM:Coils};
Complete proteome {ECO:0000313|Proteomes:UP000009136};
Reference proteome {ECO:0000313|Proteomes:UP000009136};
Wnt signaling pathway {ECO:0000256|PROSITE-ProRule:PRU00069}.
DOMAIN 88 211 RGS. {ECO:0000259|PROSITE:PS50132}.
DOMAIN 748 830 DIX. {ECO:0000259|PROSITE:PS50841}.
COILED 389 419 {ECO:0000256|SAM:Coils}.
COILED 708 731 {ECO:0000256|SAM:Coils}.
SEQUENCE 830 AA; 91634 MW; D0225280F000C5B4 CRC64;
MNIQEQGFPL DLGASFTEDA PRPPVPGEEG ELVSTDPRPV SHSFCSGKGA GIKGETSTAT
PRRSDLDLGY EPEGSASPTP PYLKWAESLH SLLDDQDGIN LFRTFLKQED CADLLDFWFA
CSGFRKLEPC DSNEEKRLKL ARAIYRKYIL DNNGIVSRQT KPATKSFIKD CISKQQIDPA
MFDQAQTEVQ STMEENTYPS FLKSDIYLEY TRTGSESPKL CSDQSSGSGT GKGVPGYLPT
LNEDEEWKCD REVDEDSGRD PAPPGRLTQK LLLETAAPRA SSSRRYSEGR ELRCGSWREP
VNPYYVNSGY ALAPATSAND SEQQSLSSDA DSLSLTDSSV DGVPPYRTRR QHRREMQESV
QANGRVPLPH IPRTYRMPKE VRVEPQKFAA ELIHRLEAVQ RTREAEEELE ERLKRVRMEE
EGEDSDMPSG PQGASHKLPS APAWHHFPSR YADVGCTGLR DAHEENPESI LDEHVQRVMR
TPGCQSPGPG HRSPDSAHVP KIGVLGGAMP GHGKHAPKLG AKLDPTGLHL HRHGHHHGHH
GAARPKEPAE AEAARRVPGS FAWGPELHGH AAKPRSHVES TGAPPAGGDG LAYGGKVGTT
SKRNSKKAEL GKSSSTEAPG PSEDAEKNQK IMQWIIEGEK EISRHRKAGH GSSGAKKQQA
HESSRPLSIE RPGAVHPWVS AQLRSSVQPS HLFIQDPTMP PNPAPNPLTQ LEEARRRLEE
EEKRASKAPS KQRTKSQRKA GGGSTQPCDS IVVAYYFCGE PIPYRTLVRG RAVTLGQFKE
LLTKKGNYRF YFKKVSDEFE CGVVFEEVRE DTAVLPVFEE KIIGKVEKVD


Related products :

Catalog number Product name Quantity
LF-PA41733 anti-Axin 1, Goat polyclonal to Axin 1, Isotype IgG, Host Goat 100 ul
AB3E122 Polyclonal Antibodies: Anti-AXIN Polyclonal Antibody; Specificity: Anti-AXIN Polyclonal Antibody ; Application: IHC 0.1mg
6005 AXIN 0.1 mg
6005 AXIN 0.5 mg
orb41087 Axin 1 antibody 100 ul
'H00008313-Q02 Axin-2 antigen 10
'H00008312-Q02-25 Axin-1 antigen 25
orb101437 Axin 2 antibody 200 ug
EH2497 Axin-1 Elisa Kit 96T
EH2487 Axin-2 Elisa Kit 96T
'H00008312-Q02-10 Axin-1 antigen 10
AXL AXIN1 Gene axin 1
'H00008313-Q01-25 Axin-2 antigen 25
orb101437 Axin 2 antibody 100 ug
orb73986 Axin 1 antibody 100 ul
orb88423 AXIN antibody 50 ug
orb95542 AXIN antibody 50 ug
'H00008313-Q01-10 Axin-2 antigen 10
'H00008313-Q02-10 Axin-2 antigen 10
'H00008313-P01 Axin-2 antigen 2
'H00008313-Q02-25 Axin-2 antigen 25
NBL1-07868 Axin 2 Lysate 0.1 mg
201-20-0556 AXIN2{axin 2}rabbit.pAb 0.1ml
ant-021 Mouse Anti Human Axin-1 100
201-20-0555 AXIN1{axin 1}rabbit.pAb 0.1ml


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur