Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

BAG family molecular chaperone regulator 7 (Bcl-2-associated athanogene 7)

 BAG7_ARATH              Reviewed;         446 AA.
Q9LVA0;
22-FEB-2012, integrated into UniProtKB/Swiss-Prot.
01-OCT-2000, sequence version 1.
25-APR-2018, entry version 97.
RecName: Full=BAG family molecular chaperone regulator 7;
AltName: Full=Bcl-2-associated athanogene 7;
Name=BAG7; OrderedLocusNames=At5g62390; ORFNames=MMI9.22;
Arabidopsis thaliana (Mouse-ear cress).
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
Arabidopsis.
NCBI_TaxID=3702;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
PubMed=10718197; DOI=10.1093/dnares/7.1.31;
Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
Tabata S.;
"Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
features of the regions of 3,076,755 bp covered by sixty P1 and TAC
clones.";
DNA Res. 7:31-63(2000).
[2]
GENOME REANNOTATION.
STRAIN=cv. Columbia;
PubMed=27862469; DOI=10.1111/tpj.13415;
Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
Town C.D.;
"Araport11: a complete reannotation of the Arabidopsis thaliana
reference genome.";
Plant J. 89:789-804(2017).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
PubMed=14593172; DOI=10.1126/science.1088305;
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J.,
Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F.,
Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.,
Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J.,
Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y.,
Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P.,
Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F.,
Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M.,
Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J.,
Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T.,
Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y.,
Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis
genome.";
Science 302:842-846(2003).
[4]
GENE FAMILY, AND NOMENCLATURE.
DOI=10.1016/S0168-9452(03)00121-3;
Juqiang Y., Cixin H., Hong Z.;
"The BAG-family proteins in Arabidopsis thaliana.";
Plant Sci. 165:1-7(2003).
[5]
GENE FAMILY.
PubMed=16636050; DOI=10.1074/jbc.M511794200;
Doukhanina E.V., Chen S., van der Zalm E., Godzik A., Reed J.,
Dickman M.B.;
"Identification and functional characterization of the BAG protein
family in Arabidopsis thaliana.";
J. Biol. Chem. 281:18793-18801(2006).
[6]
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-443, AND IDENTIFICATION
BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
PubMed=19376835; DOI=10.1104/pp.109.138677;
Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
Grossmann J., Gruissem W., Baginsky S.;
"Large-scale Arabidopsis phosphoproteome profiling reveals novel
chloroplast kinase substrates and phosphorylation networks.";
Plant Physiol. 150:889-903(2009).
[7]
FUNCTION, DISRUPTION PHENOTYPE, SUBCELLULAR LOCATION, AND INTERACTION
WITH HSP70-11/BIP2.
PubMed=20231441; DOI=10.1073/pnas.0912670107;
Williams B., Kabbage M., Britt R., Dickman M.B.;
"AtBAG7, an Arabidopsis Bcl-2-associated athanogene, resides in the
endoplasmic reticulum and is involved in the unfolded protein
response.";
Proc. Natl. Acad. Sci. U.S.A. 107:6088-6093(2010).
-!- FUNCTION: Co-chaperone that regulates diverse cellular pathways,
such as programmed cell death and stress responses. Necessary for
the proper maintenance of the unfolded protein response (UPR)
during heat and cold tolerance. {ECO:0000269|PubMed:20231441}.
-!- SUBUNIT: Binds to the ATPase domain of HSP70/HSC70 chaperones (By
similarity). Interacts with HSP70-11/BIP2. {ECO:0000250,
ECO:0000269|PubMed:20231441}.
-!- SUBCELLULAR LOCATION: Endoplasmic reticulum
{ECO:0000269|PubMed:20231441}.
-!- DOMAIN: IQ domain mediates interaction with calmodulin.
{ECO:0000250}.
-!- DISRUPTION PHENOTYPE: Susceptibility to heat and cold stress.
{ECO:0000269|PubMed:20231441}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; AB019235; BAA97203.1; -; Genomic_DNA.
EMBL; CP002688; AED97603.1; -; Genomic_DNA.
EMBL; AY093078; AAM13077.1; -; mRNA.
EMBL; AY128766; AAM91166.1; -; mRNA.
RefSeq; NP_201045.1; NM_125633.5.
UniGene; At.43914; -.
UniGene; At.52535; -.
ProteinModelPortal; Q9LVA0; -.
BioGrid; 21604; 5.
IntAct; Q9LVA0; 1.
STRING; 3702.AT5G62390.1; -.
iPTMnet; Q9LVA0; -.
PaxDb; Q9LVA0; -.
PRIDE; Q9LVA0; -.
EnsemblPlants; AT5G62390.1; AT5G62390.1; AT5G62390.
GeneID; 836360; -.
Gramene; AT5G62390.1; AT5G62390.1; AT5G62390.
KEGG; ath:AT5G62390; -.
Araport; AT5G62390; -.
TAIR; locus:2167943; AT5G62390.
eggNOG; ENOG410IKI1; Eukaryota.
eggNOG; ENOG410YFGU; LUCA.
HOGENOM; HOG000238715; -.
InParanoid; Q9LVA0; -.
OMA; LIDPYTC; -.
OrthoDB; EOG09360FM2; -.
PhylomeDB; Q9LVA0; -.
PRO; PR:Q9LVA0; -.
Proteomes; UP000006548; Chromosome 5.
ExpressionAtlas; Q9LVA0; baseline and differential.
Genevisible; Q9LVA0; AT.
GO; GO:0005783; C:endoplasmic reticulum; IDA:TAIR.
GO; GO:0005886; C:plasma membrane; IDA:TAIR.
GO; GO:0009506; C:plasmodesma; IDA:TAIR.
GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
GO; GO:0070417; P:cellular response to cold; IMP:TAIR.
GO; GO:0034605; P:cellular response to heat; IMP:TAIR.
GO; GO:0034620; P:cellular response to unfolded protein; IMP:TAIR.
GO; GO:0006457; P:protein folding; IMP:TAIR.
GO; GO:0043207; P:response to external biotic stimulus; IBA:GO_Central.
InterPro; IPR000048; IQ_motif_EF-hand-BS.
PROSITE; PS50096; IQ; 1.
1: Evidence at protein level;
Apoptosis; Calmodulin-binding; Chaperone; Complete proteome;
Endoplasmic reticulum; Phosphoprotein; Reference proteome;
Stress response.
CHAIN 1 446 BAG family molecular chaperone regulator
7.
/FTId=PRO_0000415527.
DOMAIN 303 332 IQ. {ECO:0000255|PROSITE-
ProRule:PRU00116}.
DOMAIN 330 407 BAG.
COMPBIAS 164 256 Lys-rich.
COMPBIAS 263 268 Poly-Glu.
MOD_RES 443 443 Phosphothreonine.
{ECO:0000244|PubMed:19376835}.
SEQUENCE 446 AA; 51567 MW; 95E3125F4CCC67F8 CRC64;
MTLFHRLDLI DPYTCTPLIV RETSIVEPSS LFLGFPSFID EDIEDLFEFS SPNPLDLFET
VTDLVKIKKS PSSCKYKVIR RRLEPEYPLK YLCDRVSDLE SKFDRLVSPK SDRKYTLTKE
IKGSGERKYK WEAEIQGPLE RKYKLEAEIE GSGERKYRWT TEIKGGKKDE EGLKLAALKK
EKAKAKAIAA AEAEKKKNKN KKKSYNWTTE VKSERENGEV SHTYIIKATT GGEKKKKHEE
KEKKEKIETK SKKKEKTRVV VIEEEEEEDD ESSEHGAIVL RKAFSRRNGA VRTKKGKNKE
MPPEYAAVMI QRAFKAYLIR RSKSLRALRD LAIAKTKLKE LRASFHNFSY RRLIARDGEE
RQKFSEKIIV LLLTVDAIEG VDVMVRGAKR SMVDELEAML DVVDPQPQGK SLSMRRRTFD
MPDSLIRKEI AEGVTQIVQM LETEEE


Related products :

Catalog number Product name Quantity
18-003-43726 BAG family molecular chaperone regulator 2 - Bcl-2-associated athanogene 2; BAG-2 Polyclonal 0.1 mg Protein A
18-661-15066 BAG family molecular chaperone regulator 4 - BCL2-associated athanogene 4; BAG-4; Silencer of death domains Polyclonal 0.1 mg
CE40 BAG Family Molecular Chaperone Regulator 2 BAG2 500
CE40 BAG Family Molecular Chaperone Regulator 2 BAG2 lmg
CE40 Human BAG Family Molecular Chaperone Regulator 2 BAG2 l0
E14188c Bovine ELISA Kit FOR BAG family molecular chaperone regulator 5 96T
BAG3_HUMAN Human ELISA Kit FOR BAG family molecular chaperone regulator 3 96T
C103 Human BAG Family Molecular Chaperone Regulator 2 BAG2 50
CSB-EL002533RA Rat BAG family molecular chaperone regulator 5(BAG5) ELISA kit 96T
CSB-EL002529RA Rat BAG family molecular chaperone regulator 1(BAG1) ELISA kit 96T
abx109564 Polyclonal Rabbit BAG family molecular chaperone regulator 5 Antibody 100 μg
CSB-EL002529RA Rat BAG family molecular chaperone regulator 1(BAG1) ELISA kit SpeciesRat 96T
CSB-EL002533CH Chicken BAG family molecular chaperone regulator 5(BAG5) ELISA kit 96T
abx108010 Polyclonal Rabbit BAG family molecular chaperone regulator 5 Antibody (HRP) 100 μg
abx109563 Polyclonal Rabbit BAG family molecular chaperone regulator 3 Antibody 100 μg
CE40 Recombinant Human BAG family molecular chaperone regulator 2_BAG2 1mg
CSB-EL002533RA Rat BAG family molecular chaperone regulator 5(BAG5) ELISA kit SpeciesRat 96T
CSB-EL002533MO Mouse BAG family molecular chaperone regulator 5(BAG5) ELISA kit 96T
abx108009 Polyclonal Rabbit BAG family molecular chaperone regulator 3 Antibody (HRP) 100 μg
CSB-EL002530MO Mouse BAG family molecular chaperone regulator 2(BAG2) ELISA kit 96T
CSB-EL002529MO Mouse BAG family molecular chaperone regulator 1(BAG1) ELISA kit 96T
CSB-EL002531MO Mouse BAG family molecular chaperone regulator 3(BAG3) ELISA kit 96T
CE40 Recombinant Human BAG family molecular chaperone regulator 2_BAG2 50ug
CSB-EL002532MO Mouse BAG family molecular chaperone regulator 4(BAG4) ELISA kit 96T
CSB-EL002533BO Bovine BAG family molecular chaperone regulator 5(BAG5) ELISA kit 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur