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BAG6 isoform 1 (BAG6 isoform 10) (BAG6 isoform 11) (BAG6 isoform 4)

 A0A2J8R4R3_PONAB        Unreviewed;      1126 AA.
A0A2J8R4R3;
25-APR-2018, integrated into UniProtKB/TrEMBL.
25-APR-2018, sequence version 1.
25-APR-2018, entry version 1.
SubName: Full=BAG6 isoform 1 {ECO:0000313|EMBL:PNJ03512.1};
SubName: Full=BAG6 isoform 10 {ECO:0000313|EMBL:PNJ03521.1};
SubName: Full=BAG6 isoform 11 {ECO:0000313|EMBL:PNJ03522.1};
SubName: Full=BAG6 isoform 4 {ECO:0000313|EMBL:PNJ03515.1};
ORFNames=CR201_G0054051 {ECO:0000313|EMBL:PNJ03522.1};
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Pongo.
NCBI_TaxID=9601 {ECO:0000313|EMBL:PNJ03522.1, ECO:0000313|Proteomes:UP000236516};
[1] {ECO:0000313|EMBL:PNJ03522.1, ECO:0000313|Proteomes:UP000236516}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Susie {ECO:0000313|EMBL:PNJ03522.1};
Pollen A., Hastie A., Hormozdiari F., Dougherty M., Liu R.,
Chaisson M., Hoppe E., Hill C., Pang A., Hillier L., Baker C.,
Armstrong J., Shendure J., Paten B., Wilson R., Chao H., Schneider V.,
Ventura M., Kronenberg Z., Murali S., Gordon D., Cantsilieris S.,
Munson K., Nelson B., Raja A., Underwood J., Diekhans M., Fiddes I.,
Haussler D., Eichler E.;
"High-resolution comparative analysis of great ape genomes.";
Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
-!- CAUTION: The sequence shown here is derived from an
EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
preliminary data. {ECO:0000313|EMBL:PNJ03522.1}.
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EMBL; NDHI03003761; PNJ03512.1; -; Genomic_DNA.
EMBL; NDHI03003761; PNJ03515.1; -; Genomic_DNA.
EMBL; NDHI03003761; PNJ03521.1; -; Genomic_DNA.
EMBL; NDHI03003761; PNJ03522.1; -; Genomic_DNA.
CTD; 7917; -.
GeneTree; ENSGT00390000016199; -.
Proteomes; UP000236516; Unassembled WGS sequence.
GO; GO:0071818; C:BAT3 complex; IEA:Ensembl.
GO; GO:0070062; C:extracellular exosome; IEA:Ensembl.
GO; GO:0016020; C:membrane; IEA:Ensembl.
GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
GO; GO:0030544; F:Hsp70 protein binding; IEA:Ensembl.
GO; GO:0051787; F:misfolded protein binding; IEA:Ensembl.
GO; GO:0031593; F:polyubiquitin modification-dependent protein binding; IEA:Ensembl.
GO; GO:0070628; F:proteasome binding; IEA:Ensembl.
GO; GO:0005102; F:receptor binding; IEA:Ensembl.
GO; GO:0043022; F:ribosome binding; IEA:Ensembl.
GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:Ensembl.
GO; GO:1990381; F:ubiquitin-specific protease binding; IEA:Ensembl.
GO; GO:0007420; P:brain development; IEA:Ensembl.
GO; GO:0009790; P:embryo development; IEA:Ensembl.
GO; GO:0061857; P:endoplasmic reticulum stress-induced pre-emptive quality control; IEA:Ensembl.
GO; GO:0071712; P:ER-associated misfolded protein catabolic process; IEA:Ensembl.
GO; GO:0002429; P:immune response-activating cell surface receptor signaling pathway; IEA:Ensembl.
GO; GO:0018393; P:internal peptidyl-lysine acetylation; IEA:Ensembl.
GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IEA:Ensembl.
GO; GO:0070059; P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; IEA:Ensembl.
GO; GO:0001822; P:kidney development; IEA:Ensembl.
GO; GO:0030324; P:lung development; IEA:Ensembl.
GO; GO:1904378; P:maintenance of unfolded protein involved in ERAD pathway; IEA:Ensembl.
GO; GO:0030101; P:natural killer cell activation; IEA:Ensembl.
GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
GO; GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; IEA:Ensembl.
GO; GO:1904294; P:positive regulation of ERAD pathway; IEA:Ensembl.
GO; GO:0050821; P:protein stabilization; IEA:Ensembl.
GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
GO; GO:0007130; P:synaptonemal complex assembly; IEA:Ensembl.
GO; GO:0071816; P:tail-anchored membrane protein insertion into ER membrane; IEA:Ensembl.
GO; GO:0030433; P:ubiquitin-dependent ERAD pathway; IEA:Ensembl.
InterPro; IPR021925; BAG6.
InterPro; IPR029071; Ubiquitin-like_domsf.
InterPro; IPR019954; Ubiquitin_CS.
InterPro; IPR000626; Ubiquitin_dom.
Pfam; PF12057; DUF3538; 1.
Pfam; PF00240; ubiquitin; 1.
SMART; SM00213; UBQ; 1.
SUPFAM; SSF54236; SSF54236; 1.
PROSITE; PS00299; UBIQUITIN_1; 1.
PROSITE; PS50053; UBIQUITIN_2; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000236516}.
SEQUENCE 1126 AA; 118587 MW; FB06DF9005148794 CRC64;
MEPSDSTSTA VEEPDSLEVL VKTLDSQTRT FIVGAQMNVK EFKEHIAASV SIPSEKQRLI
YQGRVLQDDK KLQEYNVGGK VIHLVERAPP QTQLPSGASS GTGSASATHG GGPPPGTRGP
GASVHDRNAN SYVMVGTFNL PSDGSAVDVH INMEQAPIQS EPRVRLVMAQ HMIRDIQTLL
SRMECRGGPQ PQHSQPPPQP PAVTPEPVAL SSQTSEPVES ETPPREPMEA EEVEERAPAQ
NPELTPGPAP AGPTPAAETN APNHPSPAEY VEVLQELQRL ESRLQPFLQR YYEVLGVAAT
TDYNNNHEGR EEDQRLINLV GESLRLLGNT FVALSDLRCN LACAPPRHLH VVRPMSHYTT
PMVLQQAAIP IQINVGTTVT MTGNGTRPPP TPNAEAPPPG PGQASSVAPS STNVESSAEG
APPPGPAPPP ATSHPRVIRI SHQSVEPVVM MHMNIQDSGT QPGGVPSAPT GPLGPPGHGQ
TLGQQVPGFP TAPTRVVIAR PTPPQARPSH PGGPPVSGTL QGAGLGTNAS LAQMVSGLVG
QLLMQPVLVA QGTPGMAPPP APATASASAG TTNTATTAGP APGGPAQPPP APQPSTADLQ
FSQLLGNLLG PAGPGAGGPG VASPTITVAM PGVPAFLQGV TDFLQATQTA PPPPPPPPPP
PPAPEQQTMP PPGSPSGGAG SPGGLGLESL SPEFFTSVVQ GVLSSLLGSL GARAGSSESI
AAFIQRLSGS SNIFEPGADG ALGFFGALLS LLCQNFSMVD VVMLLHGHFQ PLQRLQPQLR
SFFHQHYLGG QEPTPSNIRM ATHTLITGLE EYVRESFSLV QVQPGVDIIR TNLEFLQEQF
NSIAAHVLHC TDSGFGARLL ELCNQGLFEC LALNLHCLGG QQMELAAVIN GRIRRMSRGV
NPSLVSWLTT MMGLRLQVVL EHMPVGPDAI LRYVRRVGDP PQPLPEEPME VQGAERASPE
PQRENASPAP GTTAEEAMSR GPPPAPEGGS RDEQDGASAE TEPWAAAVPP EWVPIIQQDI
QSQRKVKPQP PLSDAYLSGM PAKRRKTMQG EGPQLLLSEA VSRAAKAAGA RPLTSPESLS
RDLEAPEVQE SYRQQLRSDI QKRLQEDPNY SPQRFPNAQR AFADDP


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