Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

BCL2 associated X, apoptosis regulator

 G1TWS2_RABIT            Unreviewed;       192 AA.
G1TWS2;
19-OCT-2011, integrated into UniProtKB/TrEMBL.
19-OCT-2011, sequence version 1.
30-AUG-2017, entry version 41.
SubName: Full=BCL2 associated X, apoptosis regulator {ECO:0000313|Ensembl:ENSOCUP00000021520};
Name=BAX {ECO:0000313|Ensembl:ENSOCUP00000021520};
Oryctolagus cuniculus (Rabbit).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae;
Oryctolagus.
NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000021520, ECO:0000313|Proteomes:UP000001811};
[1] {ECO:0000313|Proteomes:UP000001811}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Thorbecke inbred {ECO:0000313|Proteomes:UP000001811};
The Genome Sequencing Platform;
The Genome Assembly Team;
Lindblad-Toh K., Chang J.L., Gnerre S., Clamp M., Lander E.S.;
Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|Proteomes:UP000001811}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Thorbecke inbred {ECO:0000313|Proteomes:UP000001811};
The Genome Sequencing Platform;
The Assembly Computation and Development Core Team;
Di Palma F., Heiman D., Young S., Gnerre S., Johnson J., Lander E.S.,
Lindblad-Toh K.;
"Version 2 of The Genome Sequence of Oryctolagus cuniculus (European
rabbit).";
Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
[3] {ECO:0000313|Ensembl:ENSOCUP00000021520}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Thorbecke inbred {ECO:0000313|Ensembl:ENSOCUP00000021520};
PubMed=21993624; DOI=10.1038/nature10530;
Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J.,
Washietl S., Kheradpour P., Ernst J., Jordan G., Mauceli E.,
Ward L.D., Lowe C.B., Holloway A.K., Clamp M., Gnerre S., Alfoldi J.,
Beal K., Chang J., Clawson H., Cuff J., Di Palma F., Fitzgerald S.,
Flicek P., Guttman M., Hubisz M.J., Jaffe D.B., Jungreis I.,
Kent W.J., Kostka D., Lara M., Martins A.L., Massingham T., Moltke I.,
Raney B.J., Rasmussen M.D., Robinson J., Stark A., Vilella A.J.,
Wen J., Xie X., Zody M.C., Baldwin J., Bloom T., Chin C.W., Heiman D.,
Nicol R., Nusbaum C., Young S., Wilkinson J., Worley K.C., Kovar C.L.,
Muzny D.M., Gibbs R.A., Cree A., Dihn H.H., Fowler G., Jhangiani S.,
Joshi V., Lee S., Lewis L.R., Nazareth L.V., Okwuonu G.,
Santibanez J., Warren W.C., Mardis E.R., Weinstock G.M., Wilson R.K.,
Delehaunty K., Dooling D., Fronik C., Fulton L., Fulton B., Graves T.,
Minx P., Sodergren E., Birney E., Margulies E.H., Herrero J.,
Green E.D., Haussler D., Siepel A., Goldman N., Pollard K.S.,
Pedersen J.S., Lander E.S., Kellis M.;
"A high-resolution map of human evolutionary constraint using 29
mammals.";
Nature 478:476-482(2011).
[4] {ECO:0000313|Ensembl:ENSOCUP00000021520}
IDENTIFICATION.
STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000021520};
Ensembl;
Submitted (SEP-2011) to UniProtKB.
-!- CAUTION: The sequence shown here is derived from an Ensembl
automatic analysis pipeline and should be considered as
preliminary data. {ECO:0000313|Ensembl:ENSOCUP00000021520}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
ProteinModelPortal; G1TWS2; -.
STRING; 9986.ENSOCUP00000021520; -.
Ensembl; ENSOCUT00000024642; ENSOCUP00000021520; ENSOCUG00000006423.
eggNOG; ENOG410IWQJ; Eukaryota.
eggNOG; ENOG4112738; LUCA.
GeneTree; ENSGT00730000111112; -.
InParanoid; G1TWS2; -.
OMA; VINWIRE; -.
OrthoDB; EOG091G0YWR; -.
TreeFam; TF315834; -.
Proteomes; UP000001811; Unplaced.
Bgee; ENSOCUG00000006423; -.
GO; GO:0097144; C:BAX complex; IEA:Ensembl.
GO; GO:0071944; C:cell periphery; IEA:Ensembl.
GO; GO:0005829; C:cytosol; IEA:Ensembl.
GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:Ensembl.
GO; GO:0070062; C:extracellular exosome; IEA:Ensembl.
GO; GO:0005741; C:mitochondrial outer membrane; IEA:Ensembl.
GO; GO:0005757; C:mitochondrial permeability transition pore complex; IEA:Ensembl.
GO; GO:0005635; C:nuclear envelope; IEA:Ensembl.
GO; GO:0051434; F:BH3 domain binding; IEA:Ensembl.
GO; GO:0015267; F:channel activity; IEA:Ensembl.
GO; GO:0051087; F:chaperone binding; IEA:Ensembl.
GO; GO:0030544; F:Hsp70 protein binding; IEA:Ensembl.
GO; GO:0008289; F:lipid binding; IEA:Ensembl.
GO; GO:0046982; F:protein heterodimerization activity; IEA:Ensembl.
GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
GO; GO:0008635; P:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; IEA:Ensembl.
GO; GO:0097296; P:activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway; IEA:Ensembl.
GO; GO:1902262; P:apoptotic process involved in blood vessel morphogenesis; IEA:Ensembl.
GO; GO:1902263; P:apoptotic process involved in embryonic digit morphogenesis; IEA:Ensembl.
GO; GO:0001782; P:B cell homeostasis; IEA:Ensembl.
GO; GO:0002358; P:B cell homeostatic proliferation; IEA:Ensembl.
GO; GO:0002352; P:B cell negative selection; IEA:Ensembl.
GO; GO:1990117; P:B cell receptor apoptotic signaling pathway; IEA:Ensembl.
GO; GO:0001974; P:blood vessel remodeling; IEA:Ensembl.
GO; GO:0071310; P:cellular response to organic substance; IEA:Ensembl.
GO; GO:0034644; P:cellular response to UV; IEA:Ensembl.
GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
GO; GO:0045136; P:development of secondary sexual characteristics; IEA:Ensembl.
GO; GO:0035234; P:ectopic germ cell programmed cell death; IEA:Ensembl.
GO; GO:0010248; P:establishment or maintenance of transmembrane electrochemical gradient; IEA:Ensembl.
GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
GO; GO:0009566; P:fertilization; IEA:Ensembl.
GO; GO:0007281; P:germ cell development; IEA:Ensembl.
GO; GO:0006687; P:glycosphingolipid metabolic process; IEA:Ensembl.
GO; GO:0048873; P:homeostasis of number of cells within a tissue; IEA:Ensembl.
GO; GO:0021854; P:hypothalamus development; IEA:Ensembl.
GO; GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; IEA:Ensembl.
GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
GO; GO:0070059; P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; IEA:Ensembl.
GO; GO:0001822; P:kidney development; IEA:Ensembl.
GO; GO:0043653; P:mitochondrial fragmentation involved in apoptotic process; IEA:Ensembl.
GO; GO:0008053; P:mitochondrial fusion; IEA:Ensembl.
GO; GO:0070584; P:mitochondrion morphogenesis; IEA:Ensembl.
GO; GO:0002262; P:myeloid cell homeostasis; IEA:Ensembl.
GO; GO:2001234; P:negative regulation of apoptotic signaling pathway; IEA:Ensembl.
GO; GO:0032471; P:negative regulation of endoplasmic reticulum calcium ion concentration; IEA:Ensembl.
GO; GO:0048147; P:negative regulation of fibroblast proliferation; IEA:Ensembl.
GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
GO; GO:0033137; P:negative regulation of peptidyl-serine phosphorylation; IEA:Ensembl.
GO; GO:0032091; P:negative regulation of protein binding; IEA:Ensembl.
GO; GO:0051402; P:neuron apoptotic process; IEA:Ensembl.
GO; GO:0001764; P:neuron migration; IEA:Ensembl.
GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
GO; GO:1902512; P:positive regulation of apoptotic DNA fragmentation; IEA:Ensembl.
GO; GO:0060058; P:positive regulation of apoptotic process involved in mammary gland involution; IEA:Ensembl.
GO; GO:0002904; P:positive regulation of B cell apoptotic process; IEA:Ensembl.
GO; GO:0048087; P:positive regulation of developmental pigmentation; IEA:Ensembl.
GO; GO:1900103; P:positive regulation of endoplasmic reticulum unfolded protein response; IEA:Ensembl.
GO; GO:2001241; P:positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IEA:Ensembl.
GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
GO; GO:0032461; P:positive regulation of protein oligomerization; IEA:Ensembl.
GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IEA:Ensembl.
GO; GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; IEA:Ensembl.
GO; GO:0048597; P:post-embryonic camera-type eye morphogenesis; IEA:Ensembl.
GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
GO; GO:0001844; P:protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; IEA:Ensembl.
GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
GO; GO:0033599; P:regulation of mammary gland epithelial cell proliferation; IEA:Ensembl.
GO; GO:1902445; P:regulation of mitochondrial membrane permeability involved in programmed necrotic cell death; IEA:Ensembl.
GO; GO:0051881; P:regulation of mitochondrial membrane potential; IEA:Ensembl.
GO; GO:0006808; P:regulation of nitrogen utilization; IEA:Ensembl.
GO; GO:0043497; P:regulation of protein heterodimerization activity; IEA:Ensembl.
GO; GO:0043496; P:regulation of protein homodimerization activity; IEA:Ensembl.
GO; GO:0001836; P:release of cytochrome c from mitochondria; IEA:Ensembl.
GO; GO:0032976; P:release of matrix enzymes from mitochondria; IEA:Ensembl.
GO; GO:0048678; P:response to axon injury; IEA:Ensembl.
GO; GO:0010332; P:response to gamma radiation; IEA:Ensembl.
GO; GO:0009651; P:response to salt stress; IEA:Ensembl.
GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
GO; GO:0046666; P:retinal cell programmed cell death; IEA:Ensembl.
GO; GO:0060011; P:Sertoli cell proliferation; IEA:Ensembl.
GO; GO:0048515; P:spermatid differentiation; IEA:Ensembl.
GO; GO:0001777; P:T cell homeostatic proliferation; IEA:Ensembl.
GO; GO:0070242; P:thymocyte apoptotic process; IEA:Ensembl.
GO; GO:0060068; P:vagina development; IEA:Ensembl.
InterPro; IPR026304; BAX.
InterPro; IPR002475; Bcl2-like.
InterPro; IPR020726; Bcl2_BH2_motif_CS.
InterPro; IPR020728; Bcl2_BH3_motif_CS.
InterPro; IPR026298; Blc2_fam.
PANTHER; PTHR11256; PTHR11256; 1.
PANTHER; PTHR11256:SF52; PTHR11256:SF52; 1.
Pfam; PF00452; Bcl-2; 1.
PRINTS; PR01862; BCL2FAMILY.
SUPFAM; SSF56854; SSF56854; 1.
PROSITE; PS50062; BCL2_FAMILY; 1.
PROSITE; PS01258; BH2; 1.
PROSITE; PS01259; BH3; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000001811};
Reference proteome {ECO:0000313|Proteomes:UP000001811}.
SEQUENCE 192 AA; 21106 MW; FA80A5119512A023 CRC64;
SPGASSLLSP LGPTSSEQIM KTGALLLQGF IQDRASRMGG QTPELAVAQG PQDESTKKLS
ECLKRIGDEL DSNMELQRMI AAVDTDSPRE VFFRVAADMF ADGNFNWGRV VALFYFATKL
VLKALCTKVP ELIRTIMGWT LDFLRERLLG WIQDQGGWDG LLSYFGTPTW QTLTILGAGV
LTASLTIWKK MG


Related products :

Catalog number Product name Quantity
CSB-EL002611CH Chicken Apoptosis regulator Bcl-2(BCL2) ELISA kit 96T
CSB-EL002611BO Bovine Apoptosis regulator Bcl-2(BCL2) ELISA kit 96T
E0778m ELISA kit Apoptosis regulator Bcl-2,Bcl2,Bcl-2,Mouse,Mus musculus 96T
E0778r ELISA kit Apoptosis regulator Bcl-2,Bcl2,Bcl-2,Rat,Rattus norvegicus 96T
CSB-EL002611CH Chicken Apoptosis regulator Bcl-2(BCL2) ELISA kit SpeciesChicken 96T
E0778m ELISA Apoptosis regulator Bcl-2,Bcl2,Bcl-2,Mouse,Mus musculus 96T
E0778b ELISA Apoptosis regulator Bcl-2,BCL2,Bos taurus,Bovine 96T
E0778b ELISA kit Apoptosis regulator Bcl-2,BCL2,Bos taurus,Bovine 96T
U0778b CLIA Apoptosis regulator Bcl-2,BCL2,Bos taurus,Bovine 96T
U0778r CLIA Apoptosis regulator Bcl-2,Bcl2,Bcl-2,Rat,Rattus norvegicus 96T
E0778r ELISA Apoptosis regulator Bcl-2,Bcl2,Bcl-2,Rat,Rattus norvegicus 96T
CSB-EL002611BO Bovine Apoptosis regulator Bcl-2(BCL2) ELISA kit SpeciesBovine 96T
U0778m CLIA Apoptosis regulator Bcl-2,Bcl2,Bcl-2,Mouse,Mus musculus 96T
E0778b ELISA Kit FOR Apoptosis regulator Bcl-2; organism: Bovine; gene name: BCL2 96T
U0778h CLIA Apoptosis regulator Bcl-2,BCL2,Homo sapiens,Human 96T
E0778h ELISA kit Apoptosis regulator Bcl-2,BCL2,Homo sapiens,Human 96T
E0778h ELISA Apoptosis regulator Bcl-2,BCL2,Homo sapiens,Human 96T
E1343h ELISA kit Apoptosis regulator BAX,BAX,BCL2L4,Bcl2-L-4,Bcl-2-like protein 4,Homo sapiens,Human 96T
GWB-47C732 Apoptosis Regulator Bcl-2 (BCL2) Rabbit anti-Human Polyclonal (Ser70) Antibody
U1343h CLIA Apoptosis regulator BAX,BAX,BCL2L4,Bcl2-L-4,Bcl-2-like protein 4,Homo sapiens,Human 96T
GWB-E2C8B2 Apoptosis Regulator Bcl-2 (BCL2) Rabbit anti-Human Polyclonal (Thr56) Antibody
E1343h ELISA Apoptosis regulator BAX,BAX,BCL2L4,Bcl2-L-4,Bcl-2-like protein 4,Homo sapiens,Human 96T
U0778c CLIA Apoptosis regulator Bcl-2,BCL2,BCL-2,Chicken,Gallus gallus 96T
E0778c ELISA kit Apoptosis regulator Bcl-2,BCL2,BCL-2,Chicken,Gallus gallus 96T
E0778c ELISA Apoptosis regulator Bcl-2,BCL2,BCL-2,Chicken,Gallus gallus 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur