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Baseplate protein gp16 (Exolysin) (Gene product 16) (Gp16) (Tail lysozyme-like) (Tail-associated lysine-like protein)

 GP16_BPLSK              Reviewed;         375 AA.
O21884;
02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
01-JAN-1998, sequence version 1.
10-MAY-2017, entry version 39.
RecName: Full=Baseplate protein gp16 {ECO:0000305};
AltName: Full=Exolysin {ECO:0000305};
AltName: Full=Gene product 16 {ECO:0000305};
Short=Gp16 {ECO:0000305};
AltName: Full=Tail lysozyme-like {ECO:0000250|UniProtKB:D3WAD4};
AltName: Full=Tail-associated lysine-like protein;
Lactococcus phage SK1 (Lactococcus lactis bacteriophage SK1).
Viruses; dsDNA viruses, no RNA stage; Caudovirales; Siphoviridae;
Sk1virus.
NCBI_TaxID=31532;
NCBI_TaxID=1358; Lactococcus lactis.
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=9383189; DOI=10.1046/j.1365-2958.1997.5491926.x;
Chandry P.S., Moore S.C., Boyce J.D., Davidson B.E., Hillier A.J.;
"Analysis of the DNA sequence, gene expression, origin of replication
and modular structure of the Lactococcus lactis lytic bacteriophage
sk1.";
Mol. Microbiol. 26:49-64(1997).
-!- FUNCTION: Forms a dome thereby closing the central channel at the
end of the baseplate. Changes its conformation upon activation by
calcium allowing the channel to open at the bottom of the
baseplate for DNA ejection. {ECO:0000250|UniProtKB:D3WAD4}.
-!- SUBUNIT: Homotrimer. {ECO:0000250|UniProtKB:D3WAD4}.
-!- SUBCELLULAR LOCATION: Virion {ECO:0000250|UniProtKB:D3WAD4}.
Note=Part of the baseplate. {ECO:0000250|UniProtKB:D3WAD4}.
-!- SIMILARITY: Belongs to the skunalikevirus baseplate protein gp16
family. {ECO:0000305}.
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EMBL; AF011378; AAB70055.1; -; Genomic_DNA.
RefSeq; NP_044962.1; NC_001835.1.
SMR; O21884; -.
GeneID; 1261276; -.
KEGG; vg:1261276; -.
OrthoDB; VOG090000B2; -.
Proteomes; UP000000839; Genome.
GO; GO:0098025; C:virus tail, baseplate; IEA:UniProtKB-KW.
GO; GO:0099001; P:viral genome ejection through host cell envelope, long flexible tail mechanism; IEA:UniProtKB-KW.
InterPro; IPR031861; Caudo_ORF16.
Pfam; PF16792; Caudo_bapla16; 1.
3: Inferred from homology;
Complete proteome; Reference proteome; Viral baseplate protein;
Viral genome ejection through host cell envelope;
Viral long flexible tail ejection system;
Viral penetration into host cytoplasm; Viral tail protein; Virion;
Virus entry into host cell.
CHAIN 1 375 Baseplate protein gp16.
/FTId=PRO_0000438266.
SEQUENCE 375 AA; 42738 MW; 5F9616E02A04D34E CRC64;
MLEANVYDNF NPNYYNVSDF SMPNGKKEKR GLPIPKARCQ VINYELWETG YLYTSSATLT
VSVEVGDIVQ ILFPEVVPIE EALGKKKKLN LDMVYLVTDV DESNKATLKN YFWAMIESLD
VPNAITKTTN FAIIDYLIDP SKNNLMSYGY FFNSSIFAGK ATINRKAETS SAHDVAKRIF
SKVQFQPTTT IQHAPSETDP RNLLFINFAS RNWNRKRITT RVDIKQSVTM DTETIVERSA
YNFAVVFVKN KATDDYTDPP KMYIAKNNGD VIDYSTYHGD GTDLPDVRTA KTLFYDRDDH
GNPPALSTIK VEISPSTIVT RLIFNQNELL PLYVNDLVDI WYEGKLYSGY IADRVKTEFN
DRLIFVESGD KPNVI


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