Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Basigin (CD antigen CD147) (Fragment)

 BASI_CRIGR              Reviewed;         249 AA.
Q99PA3;
31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
01-JUN-2001, sequence version 1.
25-OCT-2017, entry version 80.
RecName: Full=Basigin;
AltName: CD_antigen=CD147;
Flags: Fragment;
Name=BSG;
Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Cricetidae; Cricetinae; Cricetulus.
NCBI_TaxID=10029;
[1]
NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Ovary;
PubMed=11353871; DOI=10.1073/pnas.111583198;
Pushkarsky T., Zybarth G., Dubrovsky L., Yurchenko V., Tang H.,
Guo H., Toole B., Sherry B., Bukrinsky M.;
"CD147 facilitates HIV-1 infection by interacting with virus-
associated cyclophilin A.";
Proc. Natl. Acad. Sci. U.S.A. 98:6360-6365(2001).
-!- FUNCTION: Plays an important role in targeting the monocarboxylate
transporters SLC16A1, SLC16A3, SLC16A8 and SLC16A11 to the plasma
membrane. Plays pivotal roles in spermatogenesis, embryo
implantation, neural network formation and tumor progression.
Stimulates adjacent fibroblasts to produce matrix
metalloproteinases (MMPS). Seems to be a receptor for
oligomannosidic glycans. In vitro, promotes outgrowth of
astrocytic processes. {ECO:0000250|UniProtKB:P35613}.
-!- SUBUNIT: Forms homooligomers in a cis-dependent manner on the
plasma membrane. Forms a complex with MMP1 at the tumor cell
surface (By similarity). Interacts with AJAP1, ATP1B2, MAG and
L1CAM (By similarity). Interacts with SLC16A1, SLC16A7 and SLC1A3;
probably a BSG dimer is associated with a monocarboxylate
transporter dimer. Interacts with PPIL2; regulates BSG transport
to the cell membrane. Interacts with SLC16A11 (By similarity).
{ECO:0000250|UniProtKB:P18572, ECO:0000250|UniProtKB:P26453,
ECO:0000250|UniProtKB:P35613}.
-!- SUBCELLULAR LOCATION: Cell membrane
{ECO:0000250|UniProtKB:P35613}; Single-pass type I membrane
protein {ECO:0000250|UniProtKB:P35613}. Melanosome
{ECO:0000250|UniProtKB:P35613}. Note=Identified by mass
spectrometry in melanosome fractions from stage I to stage IV (By
similarity). In spermatozoa, localized on the principal piece of
caput and in the middle piece during transit in the corpus and
cauda epididymides (By similarity). {ECO:0000250|UniProtKB:P18572,
ECO:0000250|UniProtKB:P35613}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AF320819; AAK09323.1; -; mRNA.
ProteinModelPortal; Q99PA3; -.
SMR; Q99PA3; -.
HOVERGEN; HBG008120; -.
GO; GO:0005887; C:integral component of plasma membrane; ISS:UniProtKB.
GO; GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO; GO:0005537; F:mannose binding; IEA:UniProtKB-KW.
GO; GO:0072659; P:protein localization to plasma membrane; ISS:UniProtKB.
Gene3D; 2.60.40.10; -; 2.
InterPro; IPR009151; Basigin.
InterPro; IPR007110; Ig-like_dom.
InterPro; IPR036179; Ig-like_dom_sf.
InterPro; IPR013783; Ig-like_fold.
InterPro; IPR003599; Ig_sub.
InterPro; IPR003598; Ig_sub2.
PANTHER; PTHR10075:SF12; PTHR10075:SF12; 1.
SMART; SM00409; IG; 1.
SMART; SM00408; IGc2; 1.
SUPFAM; SSF48726; SSF48726; 1.
PROSITE; PS50835; IG_LIKE; 2.
2: Evidence at transcript level;
Cell membrane; Disulfide bond; Glycoprotein; Immunoglobulin domain;
Lectin; Mannose-binding; Membrane; Phosphoprotein; Transmembrane;
Transmembrane helix.
CHAIN <1 249 Basigin.
/FTId=PRO_0000014517.
TOPO_DOM <1 187 Extracellular. {ECO:0000255}.
TRANSMEM 188 208 Helical. {ECO:0000255}.
TOPO_DOM 209 249 Cytoplasmic. {ECO:0000255}.
DOMAIN 1 82 Ig-like C2-type.
DOMAIN 84 179 Ig-like V-type.
MOD_RES 218 218 Phosphothreonine.
{ECO:0000250|UniProtKB:P18572}.
MOD_RES 232 232 Phosphoserine.
{ECO:0000250|UniProtKB:P35613}.
CARBOHYD 23 23 N-linked (GlcNAc...) asparagine.
{ECO:0000250}.
CARBOHYD 132 132 N-linked (GlcNAc...) asparagine.
{ECO:0000250}.
CARBOHYD 166 166 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
DISULFID 20 66 {ECO:0000255|PROSITE-ProRule:PRU00114}.
DISULFID 105 165 {ECO:0000255|PROSITE-ProRule:PRU00114}.
NON_TER 1 1
SEQUENCE 249 AA; 27414 MW; A92CDA0154A4C0CE CRC64;
AAGTIQTSVN DVGSKTHLTC SLNSSGVDII GHRWMRGGKI LQEDTLPDLQ TQYTVDIDDR
SGDYACIFLP EPVGRSNIVV EGPPRIKVGK KSEHSSEGEN VRLICKSESS HPPVTEWSWF
KTSDSGDQLI TNSSESKYVV ISTADRSELT ISNLDINSDP GTYMCNATNT QGSVQEIMTL
RVRSRLAALW PFLGIVAEVL VLVTIIFIYE KRRKPDQTLD EDDPGAAPLK GSGHHMNDKD
KNVRQRNAT


Related products :

Catalog number Product name Quantity
A7-274-T025 Mouse Monoclonal to CD147 _ Basigin _ Neurothelin Antigen CD147 Isotype IgG1 Antigen CD147 Isotype IgG1 25 tests
11-454-C100 Mouse Monoclonal to CD147 _ Basigin _ Neurothelin Antigen CD147 Isotype IgG2b Antigen CD147 Isotype IgG2b 0.1 mg
1A-274-T100 Mouse Monoclonal to CD147 _ Basigin _ Neurothelin Antigen CD147 Isotype IgG1 Antigen CD147 Isotype IgG1 100 tests
1A-274-T025 Mouse Monoclonal to CD147 _ Basigin _ Neurothelin Antigen CD147 Isotype IgG1 Antigen CD147 Isotype IgG1 25 tests
11-274-C025 Mouse Monoclonal to CD147 _ Basigin _ Neurothelin Antigen CD147 Isotype IgG1 Antigen CD147 Isotype IgG1 0.025 mg
A4-274-T025 Mouse Monoclonal to CD147 _ Basigin _ Neurothelin Antigen CD147 Isotype IgG1 Antigen CD147 Isotype IgG1 25 tests
A4-274-T100 Mouse Monoclonal to CD147 _ Basigin _ Neurothelin Antigen CD147 Isotype IgG1 Antigen CD147 Isotype IgG1 100 tests
11-454-C025 Mouse Monoclonal to CD147 _ Basigin _ Neurothelin Antigen CD147 Isotype IgG2b Antigen CD147 Isotype IgG2b 0.025 mg
A7-274-T100 Mouse Monoclonal to CD147 _ Basigin _ Neurothelin Antigen CD147 Isotype IgG1 Antigen CD147 Isotype IgG1 100 tests
11-274-C100 Mouse Monoclonal to CD147 _ Basigin _ Neurothelin Antigen CD147 Isotype IgG1 Antigen CD147 Isotype IgG1 0.1 mg
A6-274-T100 Mouse Monoclonal to CD147 _ Basigin _ Neurothelin Antigen CD147 Isotype IgG1 Antigen CD147 Isotype IgG1 100 tests
A6-274-T025 Mouse Monoclonal to CD147 _ Basigin _ Neurothelin Antigen CD147 Isotype IgG1 Antigen CD147 Isotype IgG1 25 tests
10-507-C025 Mouse Monoclonal to CD147 _ Basigin _ Neurothelin Antigen CD147 Isotype IgG1 Antigen CD147 Isotype IgG1 0.025 mg
1F-274-T100 Mouse Monoclonal to CD147 _ Basigin _ Neurothelin Antigen CD147 Isotype IgG1 Antigen CD147 Isotype IgG1 100 tests
1F-274-T025 Mouse Monoclonal to CD147 _ Basigin _ Neurothelin Antigen CD147 Isotype IgG1 Antigen CD147 Isotype IgG1 25 tests
10-507-C100 Mouse Monoclonal to CD147 _ Basigin _ Neurothelin Antigen CD147 Isotype IgG1 Antigen CD147 Isotype IgG1 0.1 mg
1B-274-C100 Mouse Monoclonal to CD147 _ Basigin _ Neurothelin Antigen CD147 Isotype IgG1 Antigen CD147 Isotype IgG1 0.1 mg
1B-274-C025 Mouse Monoclonal to CD147 _ Basigin _ Neurothelin Antigen CD147 Isotype IgG1 Antigen CD147 Isotype IgG1 0.025 mg
1P-274-T025 Mouse Monoclonal to CD147 _ Basigin _ Neurothelin Antigen CD147 Isotype IgG1 Antigen CD147 Isotype IgG1 25 tests
1P-274-T100 Mouse Monoclonal to CD147 _ Basigin _ Neurothelin Antigen CD147 Isotype IgG1 Antigen CD147 Isotype IgG1 100 tests
1P-589-T100 Mouse Monoclonal to CD147 _ Basigin _ Neurothelin Antigen CD147 Species Reactivity Human Negative Species Clone 16A1 Isotype IgG1 Application FC, ICC Immunogen CD140a_transfected NIH 3T3 cells 100 tests
1A-589-T100 Mouse Monoclonal to CD147 _ Basigin _ Neurothelin Antigen CD147 Species Reactivity Human Negative Species Clone 16A1 Isotype IgG1 Application FC, ICC Immunogen CD140a_transfected NIH 3T3 cells 100 tests
1A-589-T025 Mouse Monoclonal to CD147 _ Basigin _ Neurothelin Antigen CD147 Species Reactivity Human Negative Species Clone 16A1 Isotype IgG1 Application FC, ICC Immunogen CD140a_transfected NIH 3T3 cells 25 tests
A6-274-T100 Mouse Monoclonal to CD147 _ Basigin _ Neurothelin Antigen CD147 Species Reactivity Human, Porcine Negative Species Clone MEM_M6_1 Isotype IgG1 Application FC, IP, WB, IHC(P) Immunogen Protein 100 tests
1B-589-C025 Mouse Monoclonal to CD147 _ Basigin _ Neurothelin Antigen CD147 Species Reactivity Human Negative Species Clone 16A1 Isotype IgG1 Application FC, ICC Immunogen CD140a_transfected NIH 3T3 cells 0.025 mg


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur