Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Beta-agarase (EC 3.2.1.81) (Glycosyl hydrolase 16 family protein A) (GH16A)

 BAGA_BACPM              Reviewed;         316 AA.
B5CY73;
03-APR-2013, integrated into UniProtKB/Swiss-Prot.
14-OCT-2008, sequence version 1.
07-JUN-2017, entry version 32.
RecName: Full=Beta-agarase;
EC=3.2.1.81;
AltName: Full=Glycosyl hydrolase 16 family protein A;
Short=GH16A;
Flags: Precursor;
ORFNames=BACPLE_01670;
Bacteroides plebeius (strain DSM 17135 / JCM 12973 / M2).
Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
Bacteroides.
NCBI_TaxID=484018;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=DSM 17135 / JCM 12973 / M2;
Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M.,
Liep D., Gordon J.;
"Draft genome sequence of Bacteroides plebeius (DSM 17135).";
Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
[2]
IDENTIFICATION.
STRAIN=DSM 17135 / JCM 12973 / M2;
PubMed=20376150; DOI=10.1038/nature08937;
Hehemann J.H., Correc G., Barbeyron T., Helbert W., Czjzek M.,
Michel G.;
"Transfer of carbohydrate-active enzymes from marine bacteria to
Japanese gut microbiota.";
Nature 464:908-912(2010).
[3]
FUNCTION, AND CATALYTIC ACTIVITY.
STRAIN=DSM 17135 / JCM 12973 / M2;
PubMed=23150581; DOI=10.1073/pnas.1211002109;
Hehemann J.H., Kelly A.G., Pudlo N.A., Martens E.C., Boraston A.B.;
"Bacteria of the human gut microbiome catabolize red seaweed glycans
with carbohydrate-active enzyme updates from extrinsic microbes.";
Proc. Natl. Acad. Sci. U.S.A. 109:19786-19791(2012).
-!- FUNCTION: Cleaves the beta-1,4-linkages between beta-D-galactose
and alpha-L-3,6-anhydro-galactose residues in agarose. Cleaves
agarose in a random manner with retention of the anomeric-bond
configuration, producing beta-anomers that give rise progressively
to alpha-anomers when mutarotation takes place.
{ECO:0000269|PubMed:23150581}.
-!- CATALYTIC ACTIVITY: Hydrolysis of (1->4)-beta-D-galactosidic
linkages in agarose, giving the tetramer as the predominant
product. {ECO:0000269|PubMed:23150581}.
-!- MISCELLANEOUS: Gut bacteria supply the human body with energy from
dietary polysaccharides through glycosidases that are absent in
the human genome. Beta-agarases, which are active on agarose from
marine red algae of the genus Porphyra, are present in marine
bacteria. They are absent from metagenome data of gut bacteria,
except from the genome of the gut bacterium B.plebeius isolated
from Japanese individuals. Seaweeds make an important contribution
to the diet in Japan and Porphyra (nori) is the most important
nutritional seaweed used to prepare sushi, suggesting that
seaweeds with associated marine bacteria have been the route by
which genes coding for beta-agarases have been transferred in
human gut B.plebeius genome (PubMed:20376150 and PubMed:23150581).
-!- SIMILARITY: Belongs to the glycosyl hydrolase 16 family.
{ECO:0000305}.
-!- WEB RESOURCE: Name=Protein Spotlight; Note=A gut's tale - Issue
158 of March 2014;
URL="http://web.expasy.org/spotlight/back_issues/158/";
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; ABQC02000019; EDY95404.1; -; Genomic_DNA.
RefSeq; WP_007560915.1; NZ_DS990130.1.
ProteinModelPortal; B5CY73; -.
SMR; B5CY73; -.
STRING; 484018.BACPLE_01670; -.
CAZy; GH16; Glycoside Hydrolase Family 16.
EnsemblBacteria; EDY95404; EDY95404; BACPLE_01670.
eggNOG; ENOG4108MQB; Bacteria.
eggNOG; ENOG410YZRZ; LUCA.
OrthoDB; POG091H0F6I; -.
Proteomes; UP000003452; Unassembled WGS sequence.
GO; GO:0033916; F:beta-agarase activity; IEA:UniProtKB-EC.
GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
CDD; cd02178; GH16_beta_agarase; 1.
InterPro; IPR016287; Beta_agarase.
InterPro; IPR013320; ConA-like_dom.
InterPro; IPR000757; GH16.
Pfam; PF00722; Glyco_hydro_16; 1.
PIRSF; PIRSF001097; Agarase; 1.
SUPFAM; SSF49899; SSF49899; 1.
PROSITE; PS51762; GH16_2; 1.
1: Evidence at protein level;
Complete proteome; Glycosidase; Hydrolase; Signal.
SIGNAL 1 18 {ECO:0000255}.
CHAIN 19 316 Beta-agarase.
/FTId=PRO_0000422029.
DOMAIN 27 315 GH16. {ECO:0000255|PROSITE-
ProRule:PRU01098}.
REGION 87 97 Substrate binding.
{ECO:0000250|UniProtKB:G0L322}.
REGION 101 103 Substrate binding.
{ECO:0000250|UniProtKB:G0L322}.
ACT_SITE 167 167 Nucleophile.
{ECO:0000250|UniProtKB:G0L322}.
ACT_SITE 172 172 Proton donor.
{ECO:0000250|UniProtKB:G0L322}.
BINDING 78 78 Substrate.
{ECO:0000250|UniProtKB:G0L322}.
BINDING 197 197 Substrate.
{ECO:0000250|UniProtKB:G0L322}.
SEQUENCE 316 AA; 36274 MW; 390E5D966B4018F2 CRC64;
MKRKLFTICL ASLQFACAAE NLNNKSYEWD IYPVPANAGD GMVWKLHPQS DDFNYIADEK
DKGKEFYAKW TDFYHNHWTG PAPTIWQRDH VSVSDGFLKI RASRPEDVPL KKVVSGPNTK
ELPGTYTGCI TSKTRVKYPV YVEAYAKLSN STMASDVWML SPDDTQEIDI IEAYGGDRDG
GGYGADRLHL SHHIFIRQPF KDYQPKDSGS WYKDDKGTLW RDDFHRVGVF WKDPFTLEYY
VDGELVRTIS GKDIIDPNNY TGGTGLVKDM DIIINMEDQS WRAVKGLSPT DEELKNVEDH
TFLVDWIRVY TLVPEE


Related products :

Catalog number Product name Quantity
HEXIM2 HEXDC Gene hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing
25-786 CHIA belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily. It contains 1 chitin-binding type-2 domain. The protein degrades chitin and chitotriose. And it may participate in the d 0.05 mg
31-283 CHIA belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily. It contains 1 chitin-binding type-2 domain. The protein degrades chitin and chitotriose. And it may participate in the d 0.05 mg
26-014 SI belongs to the glycosyl hydrolase 31 family. It plays an important role in the final stage of carbohydrate digestion. 0.05 mg
30-927 LYZL6 belongs to the glycosyl hydrolase 22 family. The exact function of LYZL6 remains unknown. 0.05 mg
CSB-EL010317BO Bovine hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing (HEXDC) ELISA kit, Species Bovine, Sample Type serum, plasma 96T
CSB-EL010317HU Human hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing (HEXDC) ELISA kit, Species Human, Sample Type serum, plasma 96T
CSB-EL010317MO Mouse hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing (HEXDC) ELISA kit, Species Mouse, Sample Type serum, plasma 96T
15-288-21535 Meprin A subunit beta - EC 3.4.24.18; Endopeptidase-2; N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta; PABA peptide hydrolase; PPH beta Polyclonal 0.1 mg
15-288-21535 Meprin A subunit beta - EC 3.4.24.18; Endopeptidase-2; N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta; PABA peptide hydrolase; PPH beta Polyclonal 0.05 mg
29-755 UPB1 is a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via 0.1 mg
GCNT7_HUMAN Human ELISA Kit FOR Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7 96T
GCNT1_HUMAN Human ELISA Kit FOR Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 96T
E1371Rb Bovine ELISA Kit FOR Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 96T
E0946h Human ELISA Kit FOR Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 6 96T
GCNT1_BOVIN Bovine ELISA Kit FOR Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 96T
CSB-EL009329RA Rat Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3(GCNT3) ELISA kit 96T
CSB-EL009329MO Mouse Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3(GCNT3) ELISA kit 96T
CSB-EL009326HU Human Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase(GCNT1) ELISA kit 96T
CSB-EL009329RA Rat Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3(GCNT3) ELISA kit SpeciesRat 96T
CSB-EL009332HU Human Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7(GCNT7) ELISA kit 96T
CSB-EL009330HU Human Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4(GCNT4) ELISA kit 96T
CSB-EL009331HU Human Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 6(GCNT6) ELISA kit 96T
CSB-EL009329HU Human Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3(GCNT3) ELISA kit 96T
CSB-EL009326MO Mouse Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase(GCNT1) ELISA kit 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur