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Beta-lactoglobulin-1 (Beta-LG-1) (Beta-lactoglobulin I, major monomeric)

 LACB1_EQUAS             Reviewed;         162 AA.
P13613;
01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
01-JAN-1990, sequence version 1.
31-JAN-2018, entry version 80.
RecName: Full=Beta-lactoglobulin-1;
Short=Beta-LG-1;
AltName: Full=Beta-lactoglobulin I, major monomeric;
Name=LGB1;
Equus asinus (Donkey) (Equus africanus asinus).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
NCBI_TaxID=9793;
[1]
PROTEIN SEQUENCE.
TISSUE=Milk;
PubMed=3370127;
Godovac-Zimmermann J., Conti A., James L., Napolitano L.;
"Microanalysis of the amino-acid sequence of monomeric beta-
lactoglobulin I from donkey (Equus asinus) milk. The primary structure
and its homology with a superfamily of hydrophobic molecule
transporters.";
Biol. Chem. Hoppe-Seyler 369:171-179(1988).
-!- FUNCTION: Primary component of whey, it binds retinol and is
probably involved in the transport of that molecule.
-!- SUBUNIT: Monomer.
-!- SUBCELLULAR LOCATION: Secreted.
-!- TISSUE SPECIFICITY: Synthesized in mammary gland and secreted in
milk.
-!- SIMILARITY: Belongs to the calycin superfamily. Lipocalin family.
{ECO:0000305}.
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PIR; S00372; LGHOD.
ProteinModelPortal; P13613; -.
SMR; P13613; -.
HOVERGEN; HBG104361; -.
GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO; GO:0019841; F:retinol binding; IEA:UniProtKB-KW.
Gene3D; 2.40.128.20; -; 1.
InterPro; IPR002447; Blactoglobulin.
InterPro; IPR012674; Calycin.
InterPro; IPR002345; Lipocalin.
InterPro; IPR022272; Lipocalin_CS.
InterPro; IPR000566; Lipocln_cytosolic_FA-bd_dom.
PANTHER; PTHR11430; PTHR11430; 1.
Pfam; PF00061; Lipocalin; 1.
PRINTS; PR01172; BLCTOGLOBULN.
SUPFAM; SSF50814; SSF50814; 1.
PROSITE; PS00213; LIPOCALIN; 1.
1: Evidence at protein level;
Direct protein sequencing; Disulfide bond; Milk protein;
Retinol-binding; Secreted; Transport.
CHAIN 1 162 Beta-lactoglobulin-1.
/FTId=PRO_0000201015.
DISULFID 66 160
DISULFID 106 119
SEQUENCE 162 AA; 18528 MW; AA369B362D306C7C CRC64;
TNIPQTMQDL DLQEVAGKWH SVAMAASDIS LLDSEEAPLR VYIEKLRPTP EDNLEIILRE
GENKGCAEKK IFAEKTESPA EFKINYLDED TVFALDSDYK NYLFLCMKNA ATPGQSLVCQ
YLARTQMVDE EIMEKFRRAL QPLPGRVQIV PDLTRMAERC RI


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