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Betacellulin, epidermal growth factor family member

 H2UJG3_TAKRU            Unreviewed;       152 AA.
H2UJG3;
21-MAR-2012, integrated into UniProtKB/TrEMBL.
21-MAR-2012, sequence version 1.
30-AUG-2017, entry version 27.
SubName: Full=Betacellulin, epidermal growth factor family member {ECO:0000313|Ensembl:ENSTRUP00000037084};
Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae;
Takifugu.
NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000037084, ECO:0000313|Proteomes:UP000005226};
[1] {ECO:0000313|Ensembl:ENSTRUP00000037084}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=21551351;
Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A.,
Hosoya S., Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
"Integration of the genetic map and genome assembly of fugu
facilitates insights into distinct features of genome evolution in
teleosts and mammals.";
Genome Biol. Evol. 3:424-442(2011).
[2] {ECO:0000313|Ensembl:ENSTRUP00000037084}
IDENTIFICATION.
Ensembl;
Submitted (FEB-2012) to UniProtKB.
-!- CAUTION: Lacks conserved residue(s) required for the propagation
of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
-!- CAUTION: The sequence shown here is derived from an Ensembl
automatic analysis pipeline and should be considered as
preliminary data. {ECO:0000313|Ensembl:ENSTRUP00000037084}.
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STRING; 31033.ENSTRUP00000037084; -.
Ensembl; ENSTRUT00000037216; ENSTRUP00000037084; ENSTRUG00000014500.
eggNOG; ENOG410IWUI; Eukaryota.
eggNOG; ENOG41126JP; LUCA.
GeneTree; ENSGT00730000110951; -.
InParanoid; H2UJG3; -.
OMA; ILHCVVA; -.
OrthoDB; EOG091G0RK4; -.
TreeFam; TF332938; -.
Proteomes; UP000005226; Unplaced.
GO; GO:0005615; C:extracellular space; IBA:GO_Central.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005154; F:epidermal growth factor receptor binding; IBA:GO_Central.
GO; GO:0008083; F:growth factor activity; IBA:GO_Central.
GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; IBA:GO_Central.
GO; GO:0008284; P:positive regulation of cell proliferation; IBA:GO_Central.
InterPro; IPR013032; EGF-like_CS.
InterPro; IPR000742; EGF-like_dom.
InterPro; IPR015497; EGF_rcpt_ligand.
PANTHER; PTHR10740; PTHR10740; 1.
PROSITE; PS00022; EGF_1; 1.
PROSITE; PS01186; EGF_2; 1.
PROSITE; PS50026; EGF_3; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000005226};
Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00076};
EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
Membrane {ECO:0000256|SAM:Phobius};
Reference proteome {ECO:0000313|Proteomes:UP000005226};
Signal {ECO:0000256|SAM:SignalP};
Transmembrane {ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAM:Phobius}.
SIGNAL 1 22 {ECO:0000256|SAM:SignalP}.
CHAIN 23 152 {ECO:0000256|SAM:SignalP}.
/FTId=PRO_5003575109.
TRANSMEM 114 138 Helical. {ECO:0000256|SAM:Phobius}.
DOMAIN 60 100 EGF-like. {ECO:0000259|PROSITE:PS50026}.
DISULFID 90 99 {ECO:0000256|PROSITE-ProRule:PRU00076}.
SEQUENCE 152 AA; 17650 MW; 12F0F2FE86F28B19 CRC64;
CARVCVCVFL AAALALFKYS LAEWNVTEEL ANRTVSHCHH HSNGNNCTGD SVDNDTWHGH
FSKCPEELTG YCVHGDCRYI EEQKAPSCRC ERGFVGSRCE YLELDWWRGE KQQILIICIV
AGLVLLILLI LFICLCSNRR CRTRWQRRRR RE


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