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Betacellulin, epidermal growth factor family member

 I3JL47_ORENI            Unreviewed;       185 AA.
I3JL47;
11-JUL-2012, integrated into UniProtKB/TrEMBL.
11-JUL-2012, sequence version 1.
25-OCT-2017, entry version 33.
SubName: Full=Betacellulin, epidermal growth factor family member {ECO:0000313|Ensembl:ENSONIP00000009591};
Name=gng10 {ECO:0000313|Ensembl:ENSONIP00000009591};
Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
Pseudocrenilabrinae; Oreochromini; Oreochromis.
NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000009591, ECO:0000313|Proteomes:UP000005207};
[1] {ECO:0000313|Ensembl:ENSONIP00000009591}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Broad Institute Genome Assembly Team;
Broad Institute Sequencing Platform;
Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
"The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|Ensembl:ENSONIP00000009591}
IDENTIFICATION.
Ensembl;
Submitted (MAY-2012) to UniProtKB.
[3] {ECO:0000313|Proteomes:UP000005207}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=25186727; DOI=10.1038/nature13726;
Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J.,
Johnson J., Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J.,
Amemiya C., Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A.,
Bloomquist R., Carleton K.L., Conte M.A., D'Cotta H., Eshel O.,
Gaffney L., Galibert F., Gante H.F., Gnerre S., Greuter L., Guyon R.,
Haddad N.S., Haerty W., Harris R.M., Hofmann H.A., Hourlier T.,
Hulata G., Jaffe D.B., Lara M., Lee A.P., MacCallum I., Mwaiko S.,
Nikaido M., Nishihara H., Ozouf-Costaz C., Penman D.J., Przybylski D.,
Rakotomanga M., Renn S.C., Ribeiro F.J., Ron M., Salzburger W.,
Sanchez-Pulido L., Santos M.E., Searle S., Sharpe T., Swofford R.,
Tan F.J., Williams L., Young S., Yin S., Okada N., Kocher T.D.,
Miska E.A., Lander E.S., Venkatesh B., Fernald R.D., Meyer A.,
Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
Di Palma F.;
"The genomic substrate for adaptive radiation in African cichlid
fish.";
Nature 513:375-381(2014).
-!- CAUTION: Lacks conserved residue(s) required for the propagation
of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
-!- CAUTION: The sequence shown here is derived from an Ensembl
automatic analysis pipeline and should be considered as
preliminary data. {ECO:0000313|Ensembl:ENSONIP00000009591}.
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EMBL; AERX01026625; -; NOT_ANNOTATED_CDS; Genomic_DNA.
RefSeq; XP_013130690.1; XM_013275236.2.
STRING; 8128.ENSONIP00000009591; -.
Ensembl; ENSONIT00000009597; ENSONIP00000009591; ENSONIG00000007609.
GeneID; 100698239; -.
CTD; 2790; -.
eggNOG; ENOG410IWUI; Eukaryota.
eggNOG; ENOG41126JP; LUCA.
GeneTree; ENSGT00730000110951; -.
InParanoid; I3JL47; -.
OMA; ILHCVVA; -.
OrthoDB; EOG091G0RK4; -.
TreeFam; TF332938; -.
Proteomes; UP000005207; Unplaced.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
Gene3D; 1.20.5.100; -; 1.
InterPro; IPR021157; Cyt_c1_TM_anchor_C.
InterPro; IPR013032; EGF-like_CS.
InterPro; IPR000742; EGF-like_dom.
InterPro; IPR015497; EGF_rcpt_ligand.
PANTHER; PTHR10740; PTHR10740; 1.
PROSITE; PS00022; EGF_1; 1.
PROSITE; PS01186; EGF_2; 1.
PROSITE; PS50026; EGF_3; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000005207};
Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00076};
EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
Membrane {ECO:0000256|SAM:Phobius};
Reference proteome {ECO:0000313|Proteomes:UP000005207};
Signal {ECO:0000256|SAM:SignalP};
Transmembrane {ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAM:Phobius}.
SIGNAL 1 23 {ECO:0000256|SAM:SignalP}.
CHAIN 24 185 {ECO:0000256|SAM:SignalP}.
/FTId=PRO_5003672540.
TRANSMEM 114 137 Helical. {ECO:0000256|SAM:Phobius}.
DOMAIN 60 100 EGF-like. {ECO:0000259|PROSITE:PS50026}.
DISULFID 90 99 {ECO:0000256|PROSITE-ProRule:PRU00076}.
SEQUENCE 185 AA; 20686 MW; EFB013B94FDA8B9B CRC64;
MAKVYRRYVG IVIALALCKY CLAEWNATDV PPTGTVSDCH LHGNRDNCTD TIDTGQSNGH
FSKCPEELEH YCIHGECRYI KDQDAPSCRC QIGFIGSRCE YLNLEGQKQV KQGIIIACAI
AGLVLLILLV VFIFICSRRR RRLQSNRRRE EPRNGTEKLG MMMDSNATGS TLKPDSAEQA
LTNSV


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