Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

C-X-C motif chemokine 6 (Granulocyte chemotactic protein 2) (GCP-2) (Small-inducible cytokine B6)

 CXCL6_BOVIN             Reviewed;         112 AA.
P80221; A5PJH0; Q9GKP5;
01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
04-MAY-2001, sequence version 2.
05-DEC-2018, entry version 130.
RecName: Full=C-X-C motif chemokine 6;
AltName: Full=Granulocyte chemotactic protein 2;
Short=GCP-2;
AltName: Full=Small-inducible cytokine B6;
Flags: Precursor;
Name=CXCL6; Synonyms=GCP2, SCYB6;
Bos taurus (Bovine).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
Pecora; Bovidae; Bovinae; Bos.
NCBI_TaxID=9913;
[1]
NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Endometrium;
Austin K.J., Perry D.J., Hansen T.R.;
"The bovine granulocyte chemotactic protein-2 cDNA.";
Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases.
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=Hereford; TISSUE=Thymus;
NIH - Mammalian Gene Collection (MGC) project;
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
[3]
PROTEIN SEQUENCE OF 37-111, FUNCTION, AND PROTEOLYTIC PROCESSING OF
N-TERMINAL.
TISSUE=Kidney;
PubMed=8399143; DOI=10.1021/bi00089a037;
Proost P., Wuyts A., Conings R., Lenaerts J.-P., Billiau A.,
Opdenakker G., van Damme J.;
"Human and bovine granulocyte chemotactic protein-2: complete amino
acid sequence and functional characterization as chemokines.";
Biochemistry 32:10170-10177(1993).
-!- FUNCTION: Chemotactic for neutrophil granulocytes. Signals through
binding and activation of its receptors (CXCR1 and CXCR2). In
addition to its chemotactic and angiogenic properties, it has
strong antibacterial activity against Gram-positive and Gram-
negative bacteria (90-fold-higher when compared to CXCL5 and
CXCL7) (By similarity). {ECO:0000250, ECO:0000269|PubMed:8399143}.
-!- SUBCELLULAR LOCATION: Secreted.
-!- DEVELOPMENTAL STAGE: Expressed in high amounts from endometria of
day 18-21 pregnant cows.
-!- INDUCTION: By interferon tau and phorbol ester.
-!- SIMILARITY: Belongs to the intercrine alpha (chemokine CxC)
family. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; AF149249; AAG35212.1; -; mRNA.
EMBL; BC142108; AAI42109.1; -; mRNA.
PIR; B54188; B54188.
RefSeq; NP_776725.1; NM_174300.2.
UniGene; Bt.7165; -.
ProteinModelPortal; P80221; -.
SMR; P80221; -.
STRING; 9913.ENSBTAP00000012939; -.
PaxDb; P80221; -.
PRIDE; P80221; -.
Ensembl; ENSBTAT00000012939; ENSBTAP00000012939; ENSBTAG00000009812.
GeneID; 281735; -.
KEGG; bta:281735; -.
CTD; 6374; -.
eggNOG; ENOG410J4TR; Eukaryota.
eggNOG; ENOG41117DC; LUCA.
GeneTree; ENSGT00940000162749; -.
HOGENOM; HOG000220915; -.
HOVERGEN; HBG107789; -.
InParanoid; P80221; -.
KO; K05506; -.
OMA; LRCVCLQ; -.
OrthoDB; EOG091G132U; -.
TreeFam; TF333433; -.
Reactome; R-BTA-380108; Chemokine receptors bind chemokines.
Reactome; R-BTA-418594; G alpha (i) signalling events.
Proteomes; UP000009136; Chromosome 6.
Bgee; ENSBTAG00000009812; Expressed in 8 organ(s), highest expression level in spleen.
GO; GO:0005615; C:extracellular space; IBA:GO_Central.
GO; GO:0008009; F:chemokine activity; IDA:UniProtKB.
GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
GO; GO:0061844; P:antimicrobial humoral immune response mediated by antimicrobial peptide; IDA:UniProtKB.
GO; GO:0071222; P:cellular response to lipopolysaccharide; IDA:UniProtKB.
GO; GO:0070098; P:chemokine-mediated signaling pathway; IBA:GO_Central.
GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
GO; GO:0006955; P:immune response; IBA:GO_Central.
GO; GO:0006954; P:inflammatory response; IBA:GO_Central.
GO; GO:0030595; P:leukocyte chemotaxis; IBA:GO_Central.
GO; GO:0042119; P:neutrophil activation; IDA:UniProtKB.
GO; GO:0030593; P:neutrophil chemotaxis; IDA:UniProtKB.
CDD; cd00273; Chemokine_CXC; 1.
InterPro; IPR001089; Chemokine_CXC.
InterPro; IPR018048; Chemokine_CXC_CS.
InterPro; IPR001811; Chemokine_IL8-like_dom.
InterPro; IPR033899; CXC_Chemokine_domain.
InterPro; IPR036048; Interleukin_8-like_sf.
PANTHER; PTHR10179; PTHR10179; 1.
Pfam; PF00048; IL8; 1.
PRINTS; PR00437; SMALLCYTKCXC.
SMART; SM00199; SCY; 1.
SUPFAM; SSF54117; SSF54117; 1.
PROSITE; PS00471; SMALL_CYTOKINES_CXC; 1.
1: Evidence at protein level;
Antibiotic; Antimicrobial; Chemotaxis; Complete proteome; Cytokine;
Direct protein sequencing; Disulfide bond; Heparin-binding;
Reference proteome; Secreted; Signal.
SIGNAL 1 36 {ECO:0000269|PubMed:8399143}.
CHAIN 37 112 C-X-C motif chemokine 6.
/FTId=PRO_0000005082.
DISULFID 48 74 {ECO:0000250}.
DISULFID 50 90 {ECO:0000250}.
VARIANT 37 45 Missing (in N-terminal processing
variant).
VARIANT 37 44 Missing (in N-terminal processing
variant).
VARIANT 37 43 Missing (in N-terminal processing
variant).
VARIANT 37 38 Missing (in N-terminal processing
variant).
SEQUENCE 112 AA; 11589 MW; 6ED8148B96A7C082 CRC64;
MRLLSSRAAR VSGPSGSLCA LLALLLLTPP GPLASAGPVA AVVRELRCVC LTTTPGIHPK
TVSDLQVIAA GPQCSKVEVI ATLKNGREVC LDPEAPLIKK IVQKILDSGK NN


Related products :

Catalog number Product name Quantity
E1570h ELISA kit Chemokine alpha 3,CKA-3,C-X-C motif chemokine 6,CXCL6,GCP2,GCP-2,Granulocyte chemotactic protein 2,Homo sapiens,Human,SCYB6,Small-inducible cytokine B6 96T
U1570h CLIA Chemokine alpha 3,CKA-3,C-X-C motif chemokine 6,CXCL6,GCP2,GCP-2,Granulocyte chemotactic protein 2,Homo sapiens,Human,SCYB6,Small-inducible cytokine B6 96T
E1570h ELISA Chemokine alpha 3,CKA-3,C-X-C motif chemokine 6,CXCL6,GCP2,GCP-2,Granulocyte chemotactic protein 2,Homo sapiens,Human,SCYB6,Small-inducible cytokine B6 96T
E1570b ELISA kit Bos taurus,Bovine,C-X-C motif chemokine 6,CXCL6,GCP2,GCP-2,Granulocyte chemotactic protein 2,SCYB6,Small-inducible cytokine B6 96T
U1570b CLIA Bos taurus,Bovine,C-X-C motif chemokine 6,CXCL6,GCP2,GCP-2,Granulocyte chemotactic protein 2,SCYB6,Small-inducible cytokine B6 96T
E1570b ELISA Bos taurus,Bovine,C-X-C motif chemokine 6,CXCL6,GCP2,GCP-2,Granulocyte chemotactic protein 2,SCYB6,Small-inducible cytokine B6 96T
E0091h ELISA A-152E5.1,CC chemokine STCP-1,C-C motif chemokine 22,CCL22,Homo sapiens,Human,Macrophage-derived chemokine,MDC,MDC(1-69),SCYA22,Small-inducible cytokine A22,Stimulated T-cell chemotactic protein 96T
U0091h CLIA A-152E5.1,CC chemokine STCP-1,C-C motif chemokine 22,CCL22,Homo sapiens,Human,Macrophage-derived chemokine,MDC,MDC(1-69),SCYA22,Small-inducible cytokine A22,Stimulated T-cell chemotactic protein 96T
10-783-79182 RECOMBINANT MOUSE EOTAXIN - C-C motif chemokine 11; Small-inducible cytokine A11; Eosinophil chemotactic protein 0.01 mg
E0091h ELISA kit A-152E5.1,CC chemokine STCP-1,C-C motif chemokine 22,CCL22,Homo sapiens,Human,Macrophage-derived chemokine,MDC,MDC(1-69),SCYA22,Small-inducible cytokine A22,Stimulated T-cell chemotactic pr 96T
EIAAB06110 C-C motif chemokine 12,Ccl12,MCP-1-related chemokine,Mcp5,MCP-5,Monocyte chemoattractant protein 5,Monocyte chemotactic protein 5,Mouse,Mus musculus,Scya12,Small-inducible cytokine A12
E0026m ELISA kit C-C motif chemokine 11,Ccl11,Eosinophil chemotactic protein,Eotaxin,Mouse,Mus musculus,Scya11,Small-inducible cytokine A11 96T
U0026m CLIA C-C motif chemokine 11,Ccl11,Eosinophil chemotactic protein,Eotaxin,Mouse,Mus musculus,Scya11,Small-inducible cytokine A11 96T
U0695m CLIA C-C motif chemokine 24,Ccl24,Eosinophil chemotactic protein 2,Eotaxin-2,Mouse,Mus musculus,Scya24,Small-inducible cytokine A24 96T
E0026m ELISA C-C motif chemokine 11,Ccl11,Eosinophil chemotactic protein,Eotaxin,Mouse,Mus musculus,Scya11,Small-inducible cytokine A11 96T
E0026r ELISA C-C motif chemokine 11,Ccl11,Eosinophil chemotactic protein,Eotaxin,Rat,Rattus norvegicus,Scya11,Small-inducible cytokine A11 96T
E0695m ELISA kit C-C motif chemokine 24,Ccl24,Eosinophil chemotactic protein 2,Eotaxin-2,Mouse,Mus musculus,Scya24,Small-inducible cytokine A24 96T
E0695m ELISA C-C motif chemokine 24,Ccl24,Eosinophil chemotactic protein 2,Eotaxin-2,Mouse,Mus musculus,Scya24,Small-inducible cytokine A24 96T
E0026r ELISA kit C-C motif chemokine 11,Ccl11,Eosinophil chemotactic protein,Eotaxin,Rat,Rattus norvegicus,Scya11,Small-inducible cytokine A11 96T
U0026r CLIA C-C motif chemokine 11,Ccl11,Eosinophil chemotactic protein,Eotaxin,Rat,Rattus norvegicus,Scya11,Small-inducible cytokine A11 96T
E0026h ELISA C-C motif chemokine 11,CCL11,Eosinophil chemotactic protein,Eotaxin,Homo sapiens,Human,SCYA11,Small-inducible cytokine A11 96T
E0026h ELISA kit C-C motif chemokine 11,CCL11,Eosinophil chemotactic protein,Eotaxin,Homo sapiens,Human,SCYA11,Small-inducible cytokine A11 96T
U0026h CLIA C-C motif chemokine 11,CCL11,Eosinophil chemotactic protein,Eotaxin,Homo sapiens,Human,SCYA11,Small-inducible cytokine A11 96T
E0087b ELISA kit Acidic seminal fluid protein,Bos taurus,Bovine,C-C motif chemokine 2,CCL2,MCP-1,MCP-1A,Monocyte chemotactic protein 1A,SCYA2,Small-inducible cytokine A2 96T
E0087b ELISA Acidic seminal fluid protein,Bos taurus,Bovine,C-C motif chemokine 2,CCL2,MCP-1,MCP-1A,Monocyte chemotactic protein 1A,SCYA2,Small-inducible cytokine A2 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur | Gentaur





GENTAUR Ltd.
Unicorn House, Station Cl
Hertfordshire, Potters Bar EN6 1TL
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017
RIB 30004 00187 00010092253 10
BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG
IBAN FR76 3000 4001 8700 0100 9225 310
france@gentaur.com | Gentaur | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: +49 0241 40 08 90 86, +49 0241 95 78 94 78, +49 0241 40 08 90 86
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur | Gentaur