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CC chemokine receptor CCR5X2

 A5HEE1_HORSE            Unreviewed;       354 AA.
A5HEE1;
12-JUN-2007, integrated into UniProtKB/TrEMBL.
12-JUN-2007, sequence version 1.
05-JUL-2017, entry version 66.
SubName: Full=CC chemokine receptor CCR5X2 {ECO:0000313|EMBL:ABQ01192.1};
Name=CCR5X2 {ECO:0000313|EMBL:ABQ01192.1};
Equus caballus (Horse).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
NCBI_TaxID=9796 {ECO:0000313|EMBL:ABQ01192.1};
[1] {ECO:0000313|EMBL:ABQ01192.1}
NUCLEOTIDE SEQUENCE.
STRAIN=Galeota_X {ECO:0000313|EMBL:ABQ01192.1}, and
Galeota_Y {ECO:0000313|EMBL:ABQ01193.1};
van der Loo W., Abrantes J., Carmo C.R., Esteves P.J.;
"Innovative change at the CCR2 gene and the birth of a supplementary
chemokine receptor-like gene by recombination of CCR2 and CCR5 genes
in the equid lineage.";
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
-!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
{ECO:0000256|RuleBase:RU000688, ECO:0000256|SAAS:SAAS00594957}.
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EMBL; EF515813; ABQ01192.1; -; Genomic_DNA.
EMBL; EF515814; ABQ01193.1; -; Genomic_DNA.
eggNOG; KOG3656; Eukaryota.
eggNOG; ENOG410XRW9; LUCA.
HOGENOM; HOG000234122; -.
HOVERGEN; HBG106917; -.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0016493; F:C-C chemokine receptor activity; IEA:InterPro.
GO; GO:0006935; P:chemotaxis; IEA:InterPro.
GO; GO:0006955; P:immune response; IEA:InterPro.
GO; GO:0006954; P:inflammatory response; IEA:InterPro.
InterPro; IPR002240; Chemokine_CCR5.
InterPro; IPR000355; Chemokine_rcpt.
InterPro; IPR000276; GPCR_Rhodpsn.
InterPro; IPR017452; GPCR_Rhodpsn_7TM.
Pfam; PF00001; 7tm_1; 1.
PRINTS; PR00657; CCCHEMOKINER.
PRINTS; PR01110; CHEMOKINER5.
PRINTS; PR00237; GPCRRHODOPSN.
PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
3: Inferred from homology;
G-protein coupled receptor {ECO:0000256|RuleBase:RU000688,
ECO:0000256|SAAS:SAAS00522141};
Membrane {ECO:0000256|SAAS:SAAS00522140, ECO:0000256|SAM:Phobius};
Receptor {ECO:0000256|RuleBase:RU000688,
ECO:0000256|SAAS:SAAS00522141};
Transducer {ECO:0000256|RuleBase:RU000688,
ECO:0000256|SAAS:SAAS00522141};
Transmembrane {ECO:0000256|SAAS:SAAS00522140,
ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAAS:SAAS00522140,
ECO:0000256|SAM:Phobius}.
TRANSMEM 36 56 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 68 87 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 107 129 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 141 165 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 196 217 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 238 262 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 282 302 Helical. {ECO:0000256|SAM:Phobius}.
DOMAIN 47 299 G_PROTEIN_RECEP_F1_2.
{ECO:0000259|PROSITE:PS50262}.
SEQUENCE 354 AA; 40400 MW; B1CFD36F8D1058C8 CRC64;
MGYQTTSPFY DIDYSTSEPC QKTDVRQIAA RLLPPLYSLV FICGSLGNML VILVLIKYVK
LKRVADIYLL NLAISDLLFV LTLPLWAHYA AHSWVFGNRM CQLSIGLYFI GFFSGIFFII
LLTIDRYLAI VHRVIPLKVS TVAFGVVSSG VTWLVAVFAS LPGIIFTKSQ KEDFLESEKE
SVYSCGPYFP PQWRNFHIIM ITILSLVLPL LVMIICYSAI LKTLLQCLPR KKHKAVRLIF
VIMIVYFLFW APYNIVLLLS TFQEIFGLSD FETSSRLDQD MQVTETLGMT HCCINPIIYA
FVGEKFRRYL SMFFRKHVAK HLCKPRCPVF CGKTVERVSS RNTPSAGEQE LSIA


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