Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

CD3 antigen, epsilon polypeptide (Predicted) (CD3e molecule)

 D4A5M2_RAT              Unreviewed;       188 AA.
D4A5M2;
20-APR-2010, integrated into UniProtKB/TrEMBL.
20-APR-2010, sequence version 1.
23-MAY-2018, entry version 77.
SubName: Full=CD3 antigen, epsilon polypeptide (Predicted) {ECO:0000313|EMBL:EDL95346.1};
SubName: Full=CD3e molecule {ECO:0000313|Ensembl:ENSRNOP00000047591};
Name=Cd3e {ECO:0000313|Ensembl:ENSRNOP00000047591,
ECO:0000313|RGD:1309222};
Synonyms=Cd3e_predicted {ECO:0000313|EMBL:EDL95346.1};
ORFNames=rCG_58471 {ECO:0000313|EMBL:EDL95346.1};
Rattus norvegicus (Rat).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Rattus.
NCBI_TaxID=10116 {ECO:0000313|Ensembl:ENSRNOP00000047591, ECO:0000313|Proteomes:UP000002494};
[1] {ECO:0000313|Ensembl:ENSRNOP00000047591, ECO:0000313|Proteomes:UP000002494}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000047591,
ECO:0000313|Proteomes:UP000002494};
PubMed=15057822; DOI=10.1038/nature02426;
Rat Genome Sequencing Project Consortium;
Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J.,
Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G.,
Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G.,
Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G.,
Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S.,
Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T.,
Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T.,
Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A.,
Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M.,
Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K.,
Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S.,
Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J.,
Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y.,
Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A.,
Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J.,
D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R.,
Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A.,
Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E.,
Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E.,
Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J.,
Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D.,
Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M.,
Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O.,
Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O.,
Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H.,
Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S.,
Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J.,
Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M.,
Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E.,
Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F.,
Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K.,
Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S.,
Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M.,
Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M.,
Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A.,
Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S.,
Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G.,
Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H.,
Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R.,
Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M.,
Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H.,
Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S.,
Collins F.S.;
"Genome sequence of the Brown Norway rat yields insights into
mammalian evolution.";
Nature 428:493-521(2004).
[2] {ECO:0000313|EMBL:EDL95346.1}
NUCLEOTIDE SEQUENCE.
STRAIN=BN {ECO:0000313|EMBL:EDL95346.1};
PubMed=15632090; DOI=10.1101/gr.2889405;
Florea L., Di Francesco V., Miller J., Turner R., Yao A., Harris M.,
Walenz B., Mobarry C., Merkulov G.V., Charlab R., Dew I., Deng Z.,
Istrail S., Li P., Sutton G.;
"Gene and alternative splicing annotation with AIR.";
Genome Res. 15:54-66(2005).
[3] {ECO:0000313|EMBL:EDL95346.1}
NUCLEOTIDE SEQUENCE.
STRAIN=BN {ECO:0000313|EMBL:EDL95346.1};
Mural R.J., Li P.W., Adams M.D., Amanatides P.G., Baden-Tillson H.,
Barnstead M., Chin S.H., Dew I., Evans C.A., Ferriera S., Flanigan M.,
Fosler C., Glodek A., Gu Z., Holt R.A., Jennings D., Kraft C.L.,
Lu F., Nguyen T., Nusskern D.R., Pfannkoch C.M., Sitter C.,
Sutton G.G., Venter J.C., Wang Z., Woodage T., Zheng X.H., Zhong F.;
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
[4] {ECO:0000313|Ensembl:ENSRNOP00000047591}
IDENTIFICATION.
STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000047591};
Ensembl;
Submitted (JUL-2011) to UniProtKB.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AC136866; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; CH473975; EDL95346.1; -; Genomic_DNA.
RefSeq; NP_001101610.1; NM_001108140.1.
UniGene; Rn.96221; -.
STRING; 10116.ENSRNOP00000047591; -.
PRIDE; D4A5M2; -.
Ensembl; ENSRNOT00000047291; ENSRNOP00000047591; ENSRNOG00000016069.
GeneID; 315609; -.
KEGG; rno:315609; -.
UCSC; RGD:1309222; rat.
CTD; 916; -.
RGD; 1309222; Cd3e.
eggNOG; ENOG410IYD1; Eukaryota.
eggNOG; ENOG41123JN; LUCA.
GeneTree; ENSGT00510000048592; -.
KO; K06451; -.
OMA; QRGQNKE; -.
OrthoDB; EOG091G0PKE; -.
TreeFam; TF335892; -.
Reactome; R-RNO-198933; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell.
Reactome; R-RNO-202424; Downstream TCR signaling.
Reactome; R-RNO-202427; Phosphorylation of CD3 and TCR zeta chains.
Reactome; R-RNO-202430; Translocation of ZAP-70 to Immunological synapse.
Reactome; R-RNO-202433; Generation of second messenger molecules.
Reactome; R-RNO-389948; PD-1 signaling.
Proteomes; UP000002494; Chromosome 8.
Bgee; ENSRNOG00000016069; -.
ExpressionAtlas; D4A5M2; baseline and differential.
GO; GO:0042105; C:alpha-beta T cell receptor complex; IEA:Ensembl.
GO; GO:0044297; C:cell body; IEA:Ensembl.
GO; GO:0005911; C:cell-cell junction; IEA:Ensembl.
GO; GO:0043197; C:dendritic spine; IEA:Ensembl.
GO; GO:0009897; C:external side of plasma membrane; IEA:Ensembl.
GO; GO:0001772; C:immunological synapse; IEA:Ensembl.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0046982; F:protein heterodimerization activity; IEA:Ensembl.
GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
GO; GO:0017124; F:SH3 domain binding; IEA:Ensembl.
GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
GO; GO:0097190; P:apoptotic signaling pathway; IEA:Ensembl.
GO; GO:0021549; P:cerebellum development; IEA:Ensembl.
GO; GO:0016358; P:dendrite development; IEA:Ensembl.
GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
GO; GO:0045879; P:negative regulation of smoothened signaling pathway; IEA:Ensembl.
GO; GO:0045060; P:negative thymic T cell selection; IEA:Ensembl.
GO; GO:0046641; P:positive regulation of alpha-beta T cell proliferation; IEA:Ensembl.
GO; GO:0050850; P:positive regulation of calcium-mediated signaling; IEA:Ensembl.
GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
GO; GO:0032729; P:positive regulation of interferon-gamma production; IEA:Ensembl.
GO; GO:0045086; P:positive regulation of interleukin-2 biosynthetic process; IEA:Ensembl.
GO; GO:0032753; P:positive regulation of interleukin-4 production; IEA:Ensembl.
GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
GO; GO:0002669; P:positive regulation of T cell anergy; IEA:Ensembl.
GO; GO:0042102; P:positive regulation of T cell proliferation; IDA:RGD.
GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
GO; GO:0007584; P:response to nutrient; IDA:RGD.
GO; GO:0031295; P:T cell costimulation; IEA:Ensembl.
GO; GO:0033077; P:T cell differentiation in thymus; IEP:RGD.
GO; GO:0050852; P:T cell receptor signaling pathway; IEA:Ensembl.
Gene3D; 2.60.40.10; -; 1.
InterPro; IPR015484; CD3_esu/gsu/dsu.
InterPro; IPR007110; Ig-like_dom.
InterPro; IPR036179; Ig-like_dom_sf.
InterPro; IPR013783; Ig-like_fold.
InterPro; IPR003598; Ig_sub2.
InterPro; IPR003110; Phos_immunorcpt_sig_ITAM.
PANTHER; PTHR10570; PTHR10570; 1.
Pfam; PF02189; ITAM; 1.
SMART; SM00408; IGc2; 1.
SMART; SM00077; ITAM; 1.
SUPFAM; SSF48726; SSF48726; 1.
PROSITE; PS50835; IG_LIKE; 1.
PROSITE; PS51055; ITAM_1; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000002494};
Membrane {ECO:0000256|SAM:Phobius};
Reference proteome {ECO:0000313|Proteomes:UP000002494};
Signal {ECO:0000256|SAM:SignalP};
Transmembrane {ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAM:Phobius}.
SIGNAL 1 20 {ECO:0000256|SAM:SignalP}.
CHAIN 21 188 {ECO:0000256|SAM:SignalP}.
/FTId=PRO_5014087846.
TRANSMEM 104 128 Helical. {ECO:0000256|SAM:Phobius}.
DOMAIN 30 88 Ig-like. {ECO:0000259|PROSITE:PS50835}.
SEQUENCE 188 AA; 21312 MW; B1CF3214AB4A0ABC CRC64;
MQWNAFWSIL GLSLLAVGTC QEEYEVSISG TSVELTCPLE NEDNLKWEKN DKVLPDKNEK
HLVLEDFSEV KDSGYYVCYT ESSRKNTYLY LKARVCENCM EVDLTAVSII IIVDICITLG
LLMVVYYWSK KRKAKAKPVT RGTGTGGRPR GKAQGQNKER PPPVPNPDYE PIRKGQRDLY
SGLNQRAV


Related products :

Catalog number Product name Quantity
LF-PA40230 anti-CD3E Antigen, Epsilon Polypeptide, Rabbit polyclonal to CD3E Antigen, Epsilon Polypeptide, Isotype IgG, Host Rabbit 50 ug
GWB-EADFBF CD3E Antigen Epsilon Polypeptide (TiT3 Complex) (CD3E) Rabbit anti-Human Polyclonal (C-Terminus) Antibody
E1386092 Sheep CD3e Molecule, epsilon (CD3-TCR Complex) (CD3E) ELISA Kit 1
201-20-0930 CD3E{CD3e molecule, epsilon (CD3-TCR complex)}rabbit.pAb 0.1ml
CD3G CD3E Gene CD3e molecule, epsilon (CD3-TCR complex)
CSB-EL004931PI Pig CD3e molecule, epsilon (CD3-TCR complex) (CD3E) ELISA kit, Species Pig, Sample Type serum, plasma 96T
CSB-EL004931DO Dog CD3e molecule, epsilon (CD3-TCR complex) (CD3E) ELISA kit, Species Dog, Sample Type serum, plasma 96T
CSB-EL004931CA Cat CD3e molecule, epsilon (CD3-TCR complex) (CD3E) ELISA kit, Species Cat, Sample Type serum, plasma 96T
CSB-EL004931BO Bovine CD3e molecule, epsilon (CD3-TCR complex) (CD3E) ELISA kit, Species Bovine, Sample Type serum, plasma 96T
CSB-EL004931RB Rabbit CD3e molecule, epsilon (CD3-TCR complex) (CD3E) ELISA kit, Species Rabbit, Sample Type serum, plasma 96T
CSB-EL004931CH Chicken CD3e molecule, epsilon (CD3-TCR complex) (CD3E) ELISA kit, Species Chicken, Sample Type serum, plasma 96T
CSB-EL004931SH Sheep CD3e molecule, epsilon (CD3-TCR complex) (CD3E) ELISA kit, Species Sheep, Sample Type serum, plasma 96T
CSB-EL004931HU Human CD3e molecule, epsilon (CD3-TCR complex) (CD3E) ELISA kit, Species Human, Sample Type serum, plasma 96T
CD3E-2194H Recombinant Human CD3e Molecule, Epsilon (CD3-TCR Complex), His-tagged species: Human 50
CD3W CD3EAP Gene CD3e molecule, epsilon associated protein
GS-0327a CD3e molecule, epsilon (CD3-TCR complex) primary antibody, Host: Rabbit 200ul
CSB-EL004932HU Human CD3e molecule, epsilon associated protein (CD3EAP) ELISA kit, Species Human, Sample Type serum, plasma 96T
CSB-EL004932MO Mouse CD3e molecule, epsilon associated protein (CD3EAP) ELISA kit, Species Mouse, Sample Type serum, plasma 96T
E1872h ELISA CD3E,Homo sapiens,Human,T3E,T-cell surface antigen T3_Leu-4 epsilon chain,T-cell surface glycoprotein CD3 epsilon chain 96T
E1872h ELISA kit CD3E,Homo sapiens,Human,T3E,T-cell surface antigen T3_Leu-4 epsilon chain,T-cell surface glycoprotein CD3 epsilon chain 96T
U1872h CLIA kit CD3E,Homo sapiens,Human,T3E,T-cell surface antigen T3_Leu-4 epsilon chain,T-cell surface glycoprotein CD3 epsilon chain 96T
U1872h CLIA CD3E,Homo sapiens,Human,T3E,T-cell surface antigen T3_Leu-4 epsilon chain,T-cell surface glycoprotein CD3 epsilon chain 96T
U1872m CLIA Cd3e,Mouse,Mus musculus,T-cell surface antigen T3_Leu-4 epsilon chain,T-cell surface glycoprotein CD3 epsilon chain 96T
E1872m ELISA kit Cd3e,Mouse,Mus musculus,T-cell surface antigen T3_Leu-4 epsilon chain,T-cell surface glycoprotein CD3 epsilon chain 96T
U1872m CLIA kit Cd3e,Mouse,Mus musculus,T-cell surface antigen T3_Leu-4 epsilon chain,T-cell surface glycoprotein CD3 epsilon chain 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur