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CD30 protein

 Q800I0_CHICK            Unreviewed;       467 AA.
Q800I0;
01-JUN-2003, integrated into UniProtKB/TrEMBL.
01-JUN-2003, sequence version 1.
22-NOV-2017, entry version 100.
SubName: Full=CD30 protein {ECO:0000313|EMBL:CAC79223.1};
Name=CD30 {ECO:0000313|EMBL:CAC79223.1};
Synonyms=TNFRSF8 {ECO:0000313|Ensembl:ENSGALP00000055680};
Gallus gallus (Chicken).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes;
Phasianidae; Phasianinae; Gallus.
NCBI_TaxID=9031;
[1] {ECO:0000313|EMBL:CAC79223.1}
NUCLEOTIDE SEQUENCE.
Burgess S.C.;
Thesis (1998), Bristol University, UK.
[2] {ECO:0000313|Ensembl:ENSGALP00000055680, ECO:0000313|Proteomes:UP000000539}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Red jungle fowl {ECO:0000313|Ensembl:ENSGALP00000055680,
ECO:0000313|Proteomes:UP000000539};
PubMed=15592404; DOI=10.1038/nature03154;
International Chicken Genome Sequencing Consortium;
Hillier L.W., Miller W., Birney E., Warren W., Hardison R.C.,
Ponting C.P., Bork P., Burt D.W., Groenen M.A.M., Delany M.E.,
Dodgson J.B., Chinwalla A.T., Cliften P.F., Clifton S.W.,
Delehaunty K.D., Fronick C., Fulton R.S., Graves T.A., Kremitzki C.,
Layman D., Magrini V., McPherson J.D., Miner T.L., Minx P., Nash W.E.,
Nhan M.N., Nelson J.O., Oddy L.G., Pohl C.S., Randall-Maher J.,
Smith S.M., Wallis J.W., Yang S.-P., Romanov M.N., Rondelli C.M.,
Paton B., Smith J., Morrice D., Daniels L., Tempest H.G.,
Robertson L., Masabanda J.S., Griffin D.K., Vignal A., Fillon V.,
Jacobbson L., Kerje S., Andersson L., Crooijmans R.P., Aerts J.,
van der Poel J.J., Ellegren H., Caldwell R.B., Hubbard S.J.,
Grafham D.V., Kierzek A.M., McLaren S.R., Overton I.M., Arakawa H.,
Beattie K.J., Bezzubov Y., Boardman P.E., Bonfield J.K.,
Croning M.D.R., Davies R.M., Francis M.D., Humphray S.J., Scott C.E.,
Taylor R.G., Tickle C., Brown W.R.A., Rogers J., Buerstedde J.-M.,
Wilson S.A., Stubbs L., Ovcharenko I., Gordon L., Lucas S.,
Miller M.M., Inoko H., Shiina T., Kaufman J., Salomonsen J.,
Skjoedt K., Wong G.K.-S., Wang J., Liu B., Wang J., Yu J., Yang H.,
Nefedov M., Koriabine M., Dejong P.J., Goodstadt L., Webber C.,
Dickens N.J., Letunic I., Suyama M., Torrents D., von Mering C.,
Zdobnov E.M., Makova K., Nekrutenko A., Elnitski L., Eswara P.,
King D.C., Yang S.-P., Tyekucheva S., Radakrishnan A., Harris R.S.,
Chiaromonte F., Taylor J., He J., Rijnkels M., Griffiths-Jones S.,
Ureta-Vidal A., Hoffman M.M., Severin J., Searle S.M.J., Law A.S.,
Speed D., Waddington D., Cheng Z., Tuzun E., Eichler E., Bao Z.,
Flicek P., Shteynberg D.D., Brent M.R., Bye J.M., Huckle E.J.,
Chatterji S., Dewey C., Pachter L., Kouranov A., Mourelatos Z.,
Hatzigeorgiou A.G., Paterson A.H., Ivarie R., Brandstrom M.,
Axelsson E., Backstrom N., Berlin S., Webster M.T., Pourquie O.,
Reymond A., Ucla C., Antonarakis S.E., Long M., Emerson J.J.,
Betran E., Dupanloup I., Kaessmann H., Hinrichs A.S., Bejerano G.,
Furey T.S., Harte R.A., Raney B., Siepel A., Kent W.J., Haussler D.,
Eyras E., Castelo R., Abril J.F., Castellano S., Camara F., Parra G.,
Guigo R., Bourque G., Tesler G., Pevzner P.A., Smit A., Fulton L.A.,
Mardis E.R., Wilson R.K.;
"Sequence and comparative analysis of the chicken genome provide
unique perspectives on vertebrate evolution.";
Nature 432:695-716(2004).
[3] {ECO:0000313|EMBL:CAC79223.1}
NUCLEOTIDE SEQUENCE.
PubMed=15356338; DOI=10.1073/pnas.0305789101;
Burgess S.C., Young J.R., Baaten B.J., Hunt L., Ross L.N.,
Parcells M.S., Kumar P.M., Tregaskes C.A., Lee L.F., Davison T.F.;
"Marek's disease is a natural model for lymphomas overexpressing
Hodgkin's disease antigen (CD30).";
Proc. Natl. Acad. Sci. U.S.A. 101:13879-13884(2004).
[4] {ECO:0000313|Ensembl:ENSGALP00000055680}
IDENTIFICATION.
STRAIN=Red jungle fowl {ECO:0000313|Ensembl:ENSGALP00000055680};
Ensembl;
Submitted (OCT-2016) to UniProtKB.
-!- CAUTION: Lacks conserved residue(s) required for the propagation
of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00206}.
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EMBL; AADN04000181; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AJ276964; CAC79223.1; -; mRNA.
RefSeq; NP_989775.1; NM_204444.2.
RefSeq; XP_015152299.1; XM_015296813.1.
RefSeq; XP_015152300.1; XM_015296814.1.
RefSeq; XP_015152301.1; XM_015296815.1.
RefSeq; XP_015152302.1; XM_015296816.1.
UniGene; Gga.5180; -.
PaxDb; Q800I0; -.
PRIDE; Q800I0; -.
Ensembl; ENSGALT00000067560; ENSGALP00000055680; ENSGALG00000039741.
GeneID; 395090; -.
CTD; 943; -.
eggNOG; ENOG410IZAX; Eukaryota.
eggNOG; ENOG410YM0N; LUCA.
GeneTree; ENSGT00510000049215; -.
HOGENOM; HOG000208163; -.
TreeFam; TF331157; -.
Reactome; R-GGA-5669034; TNFs bind their physiological receptors.
PRO; PR:Q800I0; -.
Proteomes; UP000000539; Chromosome 21.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
CDD; cd13409; TNFRSF8; 1.
InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
InterPro; IPR034002; TNFRSF8_N.
Pfam; PF00020; TNFR_c6; 1.
SMART; SM00208; TNFR; 4.
PROSITE; PS00652; TNFR_NGFR_1; 2.
PROSITE; PS50050; TNFR_NGFR_2; 1.
2: Evidence at transcript level;
Complete proteome {ECO:0000313|Proteomes:UP000000539};
Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00206};
Membrane {ECO:0000256|SAM:Phobius};
Reference proteome {ECO:0000313|Proteomes:UP000000539};
Signal {ECO:0000256|SAM:SignalP};
Transmembrane {ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAM:Phobius}.
SIGNAL 1 21 {ECO:0000256|SAM:SignalP}.
CHAIN 22 467 {ECO:0000256|SAM:SignalP}.
/FTId=PRO_5010145029.
TRANSMEM 273 293 Helical. {ECO:0000256|SAM:Phobius}.
REPEAT 114 156 TNFR-Cys. {ECO:0000256|PROSITE-
ProRule:PRU00206}.
DOMAIN 114 156 TNFR-Cys. {ECO:0000259|PROSITE:PS50050}.
DISULFID 138 156 {ECO:0000256|PROSITE-ProRule:PRU00206}.
SEQUENCE 467 AA; 51350 MW; F9AD4F77DEEC8588 CRC64;
MASCSLRLGL WLLLLLQDIQ GAPQPPFTSS HSCDTLKNWF YDETLGRCCY QCPSGYAKKK
SCPMDPDEDC MRCGPEQYLN QSPKPRCDAC VLCTKEFDLV EKAPCSFNSS RVCECRPGMF
CQTAAKNTCM RCQRHTACKP GFGVKIRGTS ETDVSCEECP PGTFSDQSSS TDVCKPHTDC
AKLNKVAQGK GNATHDQVCT DQLPSYLTPD TSSIRITNET DDSDVLKRNA NPVTLASILS
SATTEIPGST PEEEALAGTS PTLAKGETTT RGLVFWAVVL SVMVLPVGML SFWQWKVCKK
RIFILKQKRS DLVDKYAKIT LTTDKCPEEE ELTDRSLPLE TNNNNLISSA EKAGSPVLSL
TEVTQSNGKA PDGPIDSQVR DHTNNQIGKI FIMNADTVIV GSSKTPGIKS CTARGYETDV
DLQEKMEEEL SMHYPEQETE VFPGNDVMVP VEEEGKEFHH PTTATEK


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