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CD36 antigen (Collagen type I receptor, thrombospondin receptor) (CD36 antigen (Collagen type I receptor, thrombospondin receptor), isoform CRA_a) (CD36 molecule isoform 1) (cDNA, FLJ93369, highly similar to Homo sapiens CD36 antigen (collagen type I receptor, thrombospondinreceptor) (CD36), mRNA)

 A4D1B1_HUMAN            Unreviewed;       472 AA.
A4D1B1;
03-APR-2007, integrated into UniProtKB/TrEMBL.
03-APR-2007, sequence version 1.
05-DEC-2018, entry version 105.
SubName: Full=CD36 antigen (Collagen type I receptor, thrombospondin receptor) {ECO:0000313|EMBL:EAL24191.1};
SubName: Full=CD36 antigen (Collagen type I receptor, thrombospondin receptor), isoform CRA_a {ECO:0000313|EMBL:EAW76996.1};
SubName: Full=CD36 molecule isoform 1 {ECO:0000313|EMBL:ALQ33419.1};
SubName: Full=cDNA, FLJ93369, highly similar to Homo sapiens CD36 antigen (collagen type I receptor, thrombospondinreceptor) (CD36), mRNA {ECO:0000313|EMBL:BAG35765.1};
Name=CD36 {ECO:0000313|EMBL:EAL24191.1};
ORFNames=hCG_17062 {ECO:0000313|EMBL:EAW76996.1},
tcag7.257 {ECO:0000313|EMBL:EAL24191.1};
Homo sapiens (Human).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
NCBI_TaxID=9606 {ECO:0000313|EMBL:EAL24191.1};
[1] {ECO:0000313|EMBL:EAW76996.1}
NUCLEOTIDE SEQUENCE.
PubMed=11181995; DOI=10.1126/science.1058040;
Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G.,
Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D.,
Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q.,
Kodira C.D., Zheng X.H., Chen L., Skupski M., Subramanian G.,
Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S.,
Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J.,
Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R.,
Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A.,
Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K.,
Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V.,
Brandon R., Cargill M., Chandramouliswaran I., Charlab R.,
Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K.,
Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z.,
Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A.,
Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V.,
Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B.,
Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J.,
Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C.,
Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L.,
Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S.,
Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A.,
Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D.,
Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L.,
Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N.,
Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S.,
Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F.,
Kline L., Koduru S., Love A., Mann F., May D., McCawley S.,
McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K.,
Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M.,
Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C.,
Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N.,
Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M.,
Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F.,
Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A.,
Mi H., Lazareva B., Hatton T., Narechania A., Diemer K.,
Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R.,
Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J.,
Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H.,
Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D.,
Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A.,
Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S.,
Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L.,
Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W.,
McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M.,
Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J.,
Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E.,
Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.;
"The sequence of the human genome.";
Science 291:1304-1351(2001).
[2] {ECO:0000313|EMBL:EAL24191.1}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=12690205; DOI=10.1126/science.1083423;
Scherer S.W., Cheung J., MacDonald J.R., Osborne L.R., Nakabayashi K.,
Herbrick J.A., Carson A.R., Parker-Katiraee L., Skaug J., Khaja R.,
Zhang J., Hudek A.K., Li M., Haddad M., Duggan G.E., Fernandez B.A.,
Kanematsu E., Gentles S., Christopoulos C.C., Choufani S.,
Kwasnicka D., Zheng X.H., Lai Z., Nusskern D., Zhang Q., Gu Z., Lu F.,
Zeesman S., Nowaczyk M.J., Teshima I., Chitayat D., Shuman C.,
Weksberg R., Zackai E.H., Grebe T.A., Cox S.R., Kirkpatrick S.J.,
Rahman N., Friedman J.M., Heng H.H., Pelicci P.G., Lo-Coco F.,
Belloni E., Shaffer L.G., Pober B., Morton C.C., Gusella J.F.,
Bruns G.A., Korf B.R., Quade B.J., Ligon A.H., Ferguson H.,
Higgins A.W., Leach N.T., Herrick S.R., Lemyre E., Farra C.G.,
Kim H.G., Summers A.M., Gripp K.W., Roberts W., Szatmari P.,
Winsor E.J., Grzeschik K.H., Teebi A., Minassian B.A., Kere J.,
Armengol L., Pujana M.A., Estivill X., Wilson M.D., Koop B.F.,
Tosi S., Moore G.E., Boright A.P., Zlotorynski E., Kerem B.,
Kroisel P.M., Petek E., Oscier D.G., Mould S.J., Dohner H., Dohner K.,
Rommens J.M., Vincent J.B., Venter J.C., Li P.W., Mural R.J.,
Adams M.D., Tsui L.C.;
"Human chromosome 7: DNA sequence and biology.";
Science 300:767-772(2003).
[3] {ECO:0000313|EMBL:EAL24191.1}
NUCLEOTIDE SEQUENCE.
Scherer S.W., Cheung J., MacDonald J.R., Osborne L.R., Nakabayashi K.,
Herbrick J.-A., Carson A.R., Parker-Katiraee L., Skaug J., Khaja R.,
Zhang J., Hudek A.K., Li M., Haddad M., Duggan G.E., Fernandez B.A.,
Kanematsu E., Gentles S., Christopoulos C.C., Choufani S.,
Kwasnicka D., Zheng X.H., Nusskern D., Zhang Q., Gu Z., Lu F.,
Zeesman S., Teshima I., Chitayat D., Shuman C., Weksberg R.,
Zackai E.H., Grebe T.A., Cox S.R., Kirkpatrick S.J., Rahman N.,
Friedman J.M., Heng H.H.Q., Pelicci P., Lococo F., Belloni E.,
Shaffer L.G., Morton C.C., Pober B., Gusella J., Bruns G., Korf B.R.,
Quade B.J., Ligon A.H., Ferguson H., Higgins A.W., Leach N.T.,
Herrick S.R., Lemyre E., Farra C.G., Kim H.-G., Summers A.M.,
Gripp K.W., Roberts W., Szatmari P., Winsor E.J.T., Grzeschik K.-H.,
Teebi A., Minassian B.A., Kere J., Armengol L., Pujana M.Angel.,
Estivill X., Wilson M.D., Koop B.F., Tosi S., Moore G.E.,
Boright A.P., Zlotorynski E., Kerem B., Kroisel P.M., Petek E.,
Oscier D.G., Mould S.J., Doehner H., Doehner K., Rommens J.M.,
Vincent J.B., Venter J.C., Li P.W., Mural R.J., Adams M.D.,
Tsui L.-C.;
Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
[4] {ECO:0000313|EMBL:EAW76996.1}
NUCLEOTIDE SEQUENCE.
Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L.,
Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
Venter J.C.;
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
[5] {ECO:0000313|EMBL:BAG35765.1}
NUCLEOTIDE SEQUENCE.
TISSUE=Mammary gland {ECO:0000313|EMBL:BAG35765.1};
Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y.,
Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R.,
Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N.,
Isogai T.;
"NEDO functional analysis of protein and research application
project.";
Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases.
[6] {ECO:0000313|EMBL:ALQ33419.1}
NUCLEOTIDE SEQUENCE.
PubMed=26871637; DOI=10.1016/j.cell.2016.01.029;
Yang X., Coulombe-Huntington J., Kang S., Sheynkman G.M., Hao T.,
Richardson A., Sun S., Yang F., Shen Y.A., Murray R., Spirohn K.,
Begg B.E., Duran-Frigola M., MacWilliams A., Pevzner S.J., Zhong Q.,
Trigg S.A., Tam S., Ghamsari L., Sahni N., Yi S., Rodriguez M.D.,
Balcha D., Tan G., Costanzo M., Andrews B., Boone C., Zhou X.J.,
Salehi-Ashtiani K., Charloteaux B., Chen A., Calderwood M.A., Aloy P.,
Roth F.P., Hill D.E., Iakoucheva L.M., Xia Y., Vidal M.;
"Widespread Expansion of Protein Interaction Capabilities by
Alternative Splicing.";
Cell 164:805-817(2016).
-!- SIMILARITY: Belongs to the CD36 family.
{ECO:0000256|SAAS:SAAS00579224}.
-----------------------------------------------------------------------
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Distributed under the Creative Commons Attribution (CC BY 4.0) License
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EMBL; KU177961; ALQ33419.1; -; mRNA.
EMBL; AK312920; BAG35765.1; -; mRNA.
EMBL; CH236949; EAL24191.1; -; Genomic_DNA.
EMBL; CH471091; EAW76996.1; -; Genomic_DNA.
EMBL; CH471091; EAW76997.1; -; Genomic_DNA.
EMBL; CH471091; EAW76998.1; -; Genomic_DNA.
EMBL; CH471091; EAW76999.1; -; Genomic_DNA.
EMBL; CH471091; EAW77000.1; -; Genomic_DNA.
EMBL; CH471091; EAW77001.1; -; Genomic_DNA.
EMBL; CH471091; EAW77002.1; -; Genomic_DNA.
EMBL; CH471091; EAW77003.1; -; Genomic_DNA.
EMBL; CH471091; EAW77004.1; -; Genomic_DNA.
EMBL; CH471091; EAW77005.1; -; Genomic_DNA.
RefSeq; NP_000063.2; NM_000072.3.
RefSeq; NP_001001547.1; NM_001001547.2.
RefSeq; NP_001001548.1; NM_001001548.2.
RefSeq; NP_001120915.1; NM_001127443.1.
RefSeq; NP_001120916.1; NM_001127444.1.
RefSeq; NP_001276840.1; NM_001289911.1.
RefSeq; XP_005250770.1; XM_005250713.1.
RefSeq; XP_005250771.1; XM_005250714.1.
RefSeq; XP_005250772.1; XM_005250715.4.
UniGene; Hs.120949; -.
SMR; A4D1B1; -.
DNASU; 948; -.
GeneID; 948; -.
KEGG; hsa:948; -.
CTD; 948; -.
EuPathDB; HostDB:ENSG00000135218.17; -.
PharmGKB; PA26212; -.
eggNOG; KOG3776; Eukaryota.
eggNOG; ENOG410XS17; LUCA.
HOVERGEN; HBG002754; -.
KO; K06259; -.
OMA; PNAFVQV; -.
OrthoDB; EOG091G0CH9; -.
ChiTaRS; CD36; human.
GenomeRNAi; 948; -.
Bgee; ENSG00000135218; Expressed in 198 organ(s), highest expression level in adipose tissue.
GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
GO; GO:0005794; C:Golgi apparatus; IDA:HPA.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
GO; GO:0006955; P:immune response; IEA:InterPro.
InterPro; IPR005428; CD36/SCARB1/SNMP1.
InterPro; IPR033076; CD36_chordates.
InterPro; IPR002159; CD36_fam.
PANTHER; PTHR11923; PTHR11923; 1.
PANTHER; PTHR11923:SF12; PTHR11923:SF12; 1.
Pfam; PF01130; CD36; 1.
PRINTS; PR01610; CD36ANTIGEN.
PRINTS; PR01609; CD36FAMILY.
2: Evidence at transcript level;
Collagen {ECO:0000313|EMBL:EAL24191.1};
Membrane {ECO:0000256|SAAS:SAAS00106193, ECO:0000256|SAM:Phobius};
Receptor {ECO:0000313|EMBL:EAL24191.1};
Transmembrane {ECO:0000256|SAAS:SAAS00106193,
ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAAS:SAAS00106193,
ECO:0000256|SAM:Phobius}.
TRANSMEM 7 29 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 440 466 Helical. {ECO:0000256|SAM:Phobius}.
NON_TER 472 472 {ECO:0000313|EMBL:ALQ33419.1}.
SEQUENCE 472 AA; 53053 MW; 543E748259A094FA CRC64;
MGCDRNCGLI AGAVIGAVLA VFGGILMPVG DLLIQKTIKK QVVLEEGTIA FKNWVKTGTE
VYRQFWIFDV QNPQEVMMNS SNIQVKQRGP YTYRVRFLAK ENVTQDAEDN TVSFLQPNGA
IFEPSLSVGT EADNFTVLNL AVAAASHIYQ NQFVQMILNS LINKSKSSMF QVRTLRELLW
GYRDPFLSLV PYPVTTTVGL FYPYNNTADG VYKVFNGKDN ISKVAIIDTY KGKRNLSYWE
SHCDMINGTD AASFPPFVEK SQVLQFFSSD ICRSIYAVFE SDVNLKGIPV YRFVLPSKAF
ASPVENPDNY CFCTEKIISK NCTSYGVLDI SKCKEGRPVY ISLPHFLYAS PDVSEPIDGL
NPNEEEHRTY LDIEPITGFT LQFAKRLQVN LLVKPSEKIQ VLKNLKRNYI VPILWLNETG
TIGDEKANMF RSQVTGKINL LGLIEMILLS VGVVMFVAFM ISYCACRSKT IK


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