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CD38 molecule

 G1L452_AILME            Unreviewed;       303 AA.
G1L452;
19-OCT-2011, integrated into UniProtKB/TrEMBL.
19-OCT-2011, sequence version 1.
05-DEC-2018, entry version 47.
SubName: Full=CD38 molecule {ECO:0000313|Ensembl:ENSAMEP00000001662};
Name=CD38 {ECO:0000313|Ensembl:ENSAMEP00000001662};
Ailuropoda melanoleuca (Giant panda).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae;
Ailuropoda.
NCBI_TaxID=9646 {ECO:0000313|Ensembl:ENSAMEP00000001662, ECO:0000313|Proteomes:UP000008912};
[1] {ECO:0000313|Ensembl:ENSAMEP00000001662}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=20010809; DOI=10.1038/nature08696;
Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q.,
Li B., Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H.,
Jian M., Li J., Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z.,
Ryder O.A., Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X.,
Guo X., Wang B., Hou R., Shen F., Mu B., Ni P., Lin R., Qian W.,
Wang G., Yu C., Nie W., Wang J., Wu Z., Liang H., Min J., Wu Q.,
Cheng S., Ruan J., Wang M., Shi Z., Wen M., Liu B., Ren X., Zheng H.,
Dong D., Cook K., Shan G., Zhang H., Kosiol C., Xie X., Lu Z.,
Zheng H., Li Y., Steiner C.C., Lam T.T., Lin S., Zhang Q., Li G.,
Tian J., Gong T., Liu H., Zhang D., Fang L., Ye C., Zhang J., Hu W.,
Xu A., Ren Y., Zhang G., Bruford M.W., Li Q., Ma L., Guo Y., An N.,
Hu Y., Zheng Y., Shi Y., Li Z., Liu Q., Chen Y., Zhao J., Qu N.,
Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X., Vinar T., Wang Y.,
Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y., Wang X.,
Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H.,
Wang J., Wang J.;
"The sequence and de novo assembly of the giant panda genome.";
Nature 463:311-317(2010).
[2] {ECO:0000313|Ensembl:ENSAMEP00000001662}
IDENTIFICATION.
Ensembl;
Submitted (SEP-2011) to UniProtKB.
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EMBL; ACTA01065827; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; ACTA01073827; -; NOT_ANNOTATED_CDS; Genomic_DNA.
RefSeq; XP_002916293.1; XM_002916247.3.
STRING; 9646.ENSAMEP00000001662; -.
Ensembl; ENSAMET00000001725; ENSAMEP00000001662; ENSAMEG00000001557.
GeneID; 100481326; -.
KEGG; aml:100481326; -.
CTD; 952; -.
eggNOG; ENOG410IH8E; Eukaryota.
eggNOG; ENOG4111W33; LUCA.
GeneTree; ENSGT00390000017291; -.
InParanoid; G1L452; -.
KO; K01242; -.
OMA; CVKNPEH; -.
OrthoDB; EOG091G0GI3; -.
TreeFam; TF332530; -.
Proteomes; UP000008912; Unassembled WGS sequence.
GO; GO:0009986; C:cell surface; IEA:Ensembl.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
GO; GO:0050135; F:NAD(P)+ nucleosidase activity; IEA:InterPro.
GO; GO:0003953; F:NAD+ nucleosidase activity; IEA:InterPro.
GO; GO:0016849; F:phosphorus-oxygen lyase activity; IEA:Ensembl.
GO; GO:0050853; P:B cell receptor signaling pathway; IEA:Ensembl.
GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
GO; GO:0030890; P:positive regulation of B cell proliferation; IEA:Ensembl.
GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
GO; GO:0042493; P:response to drug; IEA:Ensembl.
CDD; cd04759; Rib_hydrolase; 1.
InterPro; IPR003193; ADP-ribosyl_cyclase.
InterPro; IPR033567; CD38.
PANTHER; PTHR10912; PTHR10912; 1.
PANTHER; PTHR10912:SF5; PTHR10912:SF5; 1.
Pfam; PF02267; Rib_hydrolayse; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000008912};
Membrane {ECO:0000256|SAM:Phobius};
Reference proteome {ECO:0000313|Proteomes:UP000008912};
Transmembrane {ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAM:Phobius}.
TRANSMEM 24 47 Helical. {ECO:0000256|SAM:Phobius}.
SEQUENCE 303 AA; 34406 MW; 8773DB374759950E CRC64;
MASHRFSSVS EEEPCCDISR KTKICLCVFF GLLIVVVIAV PVGILMWPRP HKEWKGEGTT
AHFYEILMGR CYTYTQIVRP ELGHKDCQKI GKAFTSAFLS KDPCSSTEQD YEPLMELTNQ
AVPCNKTLFW SKSSQLAHDY TRVRQNMFTL EDTLLGYMAD GLRWCGDSGS SDMNYKSCPN
WREDCSNNSF SVFWNTVSKR FAEDACGVVH VVLNGSISNP FDERSTFGRV EVFNLRPEKV
HRLQAWVMHD IGSAGSDSCS SSSINVLKWI LKERSIAFSC ENNYGPIRLL QCVKNPEHPS
CRF


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