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CD47 molecule

 H2QN21_PANTR            Unreviewed;       298 AA.
H2QN21;
21-MAR-2012, integrated into UniProtKB/TrEMBL.
28-FEB-2018, sequence version 2.
07-NOV-2018, entry version 31.
SubName: Full=CD47 molecule {ECO:0000313|Ensembl:ENSPTRP00000026209};
Name=CD47 {ECO:0000313|Ensembl:ENSPTRP00000026209,
ECO:0000313|VGNC:VGNC:11369};
Pan troglodytes (Chimpanzee).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Pan.
NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000026209, ECO:0000313|Proteomes:UP000002277};
[1] {ECO:0000313|Ensembl:ENSPTRP00000026209, ECO:0000313|Proteomes:UP000002277}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=16136131; DOI=10.1038/nature04072;
Chimpanzee sequencing and analysis consortium;
"Initial sequence of the chimpanzee genome and comparison with the
human genome.";
Nature 437:69-87(2005).
[2] {ECO:0000313|Ensembl:ENSPTRP00000026209}
IDENTIFICATION.
Ensembl;
Submitted (FEB-2012) to UniProtKB.
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EMBL; AACZ04048037; -; NOT_ANNOTATED_CDS; Genomic_DNA.
STRING; 9598.ENSPTRP00000026209; -.
PaxDb; H2QN21; -.
Ensembl; ENSPTRT00000028400; ENSPTRP00000026209; ENSPTRG00000015188.
VGNC; VGNC:11369; CD47.
eggNOG; ENOG410IJTS; Eukaryota.
eggNOG; ENOG41113GI; LUCA.
GeneTree; ENSGT00390000007697; -.
InParanoid; H2QN21; -.
OrthoDB; EOG091G0HUR; -.
TreeFam; TF336026; -.
Proteomes; UP000002277; Chromosome 3.
Bgee; ENSPTRG00000015188; Expressed in 6 organ(s), highest expression level in prefrontal cortex.
GO; GO:0070062; C:extracellular exosome; IBA:GO_Central.
GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
GO; GO:0070053; F:thrombospondin receptor activity; IBA:GO_Central.
GO; GO:0022409; P:positive regulation of cell-cell adhesion; IBA:GO_Central.
GO; GO:0050729; P:positive regulation of inflammatory response; IBA:GO_Central.
GO; GO:0050766; P:positive regulation of phagocytosis; IBA:GO_Central.
CDD; cd16090; IgV_CD47; 1.
Gene3D; 2.60.40.10; -; 1.
InterPro; IPR006704; CD47.
InterPro; IPR013147; CD47_TM.
InterPro; IPR013270; CD47_Vset.
InterPro; IPR007110; Ig-like_dom.
InterPro; IPR036179; Ig-like_dom_sf.
InterPro; IPR013783; Ig-like_fold.
InterPro; IPR037805; IgV_CD47.
PANTHER; PTHR10613; PTHR10613; 1.
Pfam; PF04549; CD47; 1.
Pfam; PF08204; V-set_CD47; 1.
SUPFAM; SSF48726; SSF48726; 1.
PROSITE; PS50835; IG_LIKE; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000002277};
Membrane {ECO:0000256|SAM:Phobius};
Reference proteome {ECO:0000313|Proteomes:UP000002277};
Signal {ECO:0000256|SAM:SignalP};
Transmembrane {ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAM:Phobius}.
SIGNAL 1 15 {ECO:0000256|SAM:SignalP}.
CHAIN 16 298 {ECO:0000256|SAM:SignalP}.
/FTId=PRO_5014131381.
TRANSMEM 140 162 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 174 195 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 207 225 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 234 261 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 267 288 Helical. {ECO:0000256|SAM:Phobius}.
DOMAIN 31 124 Ig-like. {ECO:0000259|PROSITE:PS50835}.
SEQUENCE 298 AA; 32551 MW; 20AC9223504BDE51 CRC64;
LSITLALLLV TFVCSQLLFN KTKSVEFTFC NDTVVIPCFV TNMEAQNTTE VYVKWKFKGR
DIYTFDGALN KSTVPTDFSS AKIEVSQLLK GDASLKMDKS DAVSHTGNYT CEVTELTREG
ETIIELKYRV VSWFSPNENI LIVIFPIFAI LLFWGQFGIK TLKYRSGGMD EKTIALLVAG
LMVTVIVIVG AILFVPGEYS LKNATGLGLI VTSTGILILL HYYVFSTAIG LTSFVIAILV
IQVIAYILAV VGLSLCIAAC IPMHGPLLIS GLSILALAQL LGLVYMKFVA MLPPQPPK


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