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CD47 molecule
M3YET2_MUSPF Unreviewed; 306 AA.
M3YET2;
01-MAY-2013, integrated into UniProtKB/TrEMBL.
01-MAY-2013, sequence version 1.
28-MAR-2018, entry version 25.
SubName: Full=CD47 molecule {ECO:0000313|Ensembl:ENSMPUP00000009839};
Name=CD47 {ECO:0000313|Ensembl:ENSMPUP00000009839};
Mustela putorius furo (European domestic ferret) (Mustela furo).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Mustelidae;
Mustelinae; Mustela.
NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000009839, ECO:0000313|Proteomes:UP000000715};
[1] {ECO:0000313|Ensembl:ENSMPUP00000009839}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ID#1420 {ECO:0000313|Ensembl:ENSMPUP00000009839};
Di Palma F., Alfoldi J., Johnson J., Jaffe D., Berlin A., Gnerre S.,
Grabherr M., Hall G., Lara M., MacCallum I., Mauceli E.,
Przyblyski D., Ribeiro F., Russell P., Sharpe T., Turner-Maier J.,
Walker B.J., Young S., Birren B., Lindblad-Toh K.;
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|Ensembl:ENSMPUP00000009839}
IDENTIFICATION.
Ensembl;
Submitted (MAR-2013) to UniProtKB.
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EMBL; AEYP01071944; -; NOT_ANNOTATED_CDS; Genomic_DNA.
STRING; 9669.ENSMPUP00000009839; -.
Ensembl; ENSMPUT00000009999; ENSMPUP00000009839; ENSMPUG00000009914.
eggNOG; ENOG410IJTS; Eukaryota.
eggNOG; ENOG41113GI; LUCA.
GeneTree; ENSGT00390000007697; -.
InParanoid; M3YET2; -.
OMA; VYMKFVA; -.
OrthoDB; EOG091G0HUR; -.
Proteomes; UP000000715; Unassembled WGS sequence.
GO; GO:0070062; C:extracellular exosome; IEA:Ensembl.
GO; GO:0005887; C:integral component of plasma membrane; IEA:Ensembl.
GO; GO:0070053; F:thrombospondin receptor activity; IEA:Ensembl.
GO; GO:0008228; P:opsonization; IEA:Ensembl.
GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
GO; GO:0050729; P:positive regulation of inflammatory response; IEA:Ensembl.
GO; GO:0050766; P:positive regulation of phagocytosis; IEA:Ensembl.
GO; GO:0050870; P:positive regulation of T cell activation; IEA:Ensembl.
GO; GO:0009617; P:response to bacterium; IEA:Ensembl.
CDD; cd16090; IgV_CD47; 1.
Gene3D; 2.60.40.10; -; 1.
InterPro; IPR006704; CD47.
InterPro; IPR013147; CD47_TM.
InterPro; IPR013270; CD47_Vset.
InterPro; IPR007110; Ig-like_dom.
InterPro; IPR013783; Ig-like_fold.
InterPro; IPR037805; IgV_CD47.
PANTHER; PTHR10613; PTHR10613; 1.
Pfam; PF04549; CD47; 1.
Pfam; PF08204; V-set_CD47; 1.
PROSITE; PS50835; IG_LIKE; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000000715};
Membrane {ECO:0000256|SAM:Phobius};
Reference proteome {ECO:0000313|Proteomes:UP000000715};
Transmembrane {ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAM:Phobius}.
TRANSMEM 126 148 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 160 181 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 193 213 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 220 241 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 253 272 Helical. {ECO:0000256|SAM:Phobius}.
DOMAIN 19 110 Ig-like. {ECO:0000259|PROSITE:PS50835}.
SEQUENCE 306 AA; 33574 MW; B3F600A89FC0AAF4 CRC64;
GSAQLIFNIT KSVEYTACNE SVIIPCFVNN VEATNINEMY VKWKLKGKDI FTFNGALQKT
THGDKFKSTK IIPQKLLTGI ASLEMDKEEA VVGNYTCEVT ELSREGETII ELKYRIVSWF
SPNENILIVI FPILAVLLSW GQFGIVTIKY KSSLVKEKTI LLFVGGLVLT IVVIVGAILF
VPGEYSTKNS CGLGLIVIPT VILILLQYCV FIIGVWISPF TIAILILQVL GYVLSVVGLS
LCVSECNPVH GPLLISGLGI IALAELLGLV YMKLVASNQK TIQPPRKAVE EPLNAFKESK
GMMNDE
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Pathways :
WP1932: Transmembrane transport of small molecules
WP1937: Transport of vitamins, nucleosides, and related molecules
WP1963: The effect of Glucocorticoids on target gene expression
WP2328: Allograft rejection
WP2431: Spinal Cord Injury
WP2432: Spinal Cord Injury
WP2433: Spinal Cord Injury
Related Genes :
[Cd47] Leukocyte surface antigen CD47 (Integrin-associated protein) (IAP) (CD antigen CD47)
[CD47 MER6] Leukocyte surface antigen CD47 (Antigenic surface determinant protein OA3) (Integrin-associated protein) (IAP) (Protein MER6) (CD antigen CD47)
[Cd47] Leukocyte surface antigen CD47 (Integrin-associated protein) (IAP) (CD antigen CD47)
[CD47] Leukocyte surface antigen CD47 (Integrin-associated protein) (IAP) (CD antigen CD47)
[CD47] Leukocyte surface antigen CD47 (Integrin-associated protein) (IAP) (CD antigen CD47)
[CD47] Leukocyte surface antigen CD47 (Integrin-associated protein) (IAP) (CD antigen CD47)
[SIRPG SIRPB2] Signal-regulatory protein gamma (SIRP-gamma) (CD172 antigen-like family member B) (Signal-regulatory protein beta-2) (SIRP-b2) (SIRP-beta-2) (CD antigen CD172g)
[SIRPA BIT MFR MYD1 PTPNS1 SHPS1 SIRP] Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (Macrophage fusion receptor) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (Signal-regulatory protein alpha-2) (Sirp-alpha-2) (Signal-regulatory protein alpha-3) (Sirp-alpha-3) (p84) (CD antigen CD172a)
[CD47] CD47 glycoprotein isoform A (CD47 molecule)
[CD47] CD47 molecule (Leukocyte surface antigen CD47)
[CD47] CD47 molecule (Leukocyte surface antigen CD47 isoform 1)
[CD47] CD47 molecule (Leukocyte surface antigen CD47 isoform 1)
[Sirpa Bit Myd1 Ptpns1 Shps1 Sirp] Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (mSIRP-alpha1) (p84) (CD antigen CD172a)
[Ubqln1 Plic1] Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1)
[Ubqln2 Plic2] Ubiquilin-2 (Chap1) (DSK2 homolog) (Protein linking IAP with cytoskeleton 2) (PLIC-2) (Ubiquitin-like product Chap1/Dsk2)
[CD47] CD47 molecule
[CD47] CD47 molecule
[CD47] CD47 molecule
[CD47] CD47 molecule
[CD47] Leukocyte surface antigen CD47
[CD47] CD47 molecule
[CD47] CD47 molecule
[CD47] CD47 molecule
[CD47] CD47 molecule
[SIRPA MYD1 PTPNS1 SHPS1 SIRP] Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (CD antigen CD172a)
[Sirpa Bit Mfr Ptpns1 Shps1 Sirp] Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (Macrophage fusion receptor) (Macrophage membrane protein MFP150) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (CD antigen CD172a)
[CD47] CD47 molecule
[Cd47] Leukocyte surface antigen CD47
[CD47] CD47 molecule
[CD47] CD47 molecule
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