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CD59 molecule, complement regulatory protein

 H2Q3D9_PANTR            Unreviewed;       130 AA.
H2Q3D9;
21-MAR-2012, integrated into UniProtKB/TrEMBL.
28-FEB-2018, sequence version 2.
25-APR-2018, entry version 40.
SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPTRP00000006057};
Name=CD59 {ECO:0000313|VGNC:VGNC:11287};
Synonyms=C11H11orf91 {ECO:0000313|Ensembl:ENSPTRP00000006057};
Pan troglodytes (Chimpanzee).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Pan.
NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000006057, ECO:0000313|Proteomes:UP000002277};
[1] {ECO:0000313|Ensembl:ENSPTRP00000006057, ECO:0000313|Proteomes:UP000002277}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=16136131; DOI=10.1038/nature04072;
Chimpanzee sequencing and analysis consortium;
"Initial sequence of the chimpanzee genome and comparison with the
human genome.";
Nature 437:69-87(2005).
[2] {ECO:0000313|Ensembl:ENSPTRP00000006057}
IDENTIFICATION.
Ensembl;
Submitted (FEB-2012) to UniProtKB.
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EMBL; AACZ04016457; -; NOT_ANNOTATED_CDS; Genomic_DNA.
STRING; 9598.ENSPTRP00000006057; -.
Ensembl; ENSPTRT00000006570; ENSPTRP00000006057; ENSPTRG00000003489.
VGNC; VGNC:11287; CD59.
eggNOG; ENOG410J39P; Eukaryota.
eggNOG; ENOG410ZEQP; LUCA.
GeneTree; ENSGT00390000002169; -.
OMA; NSDLCNS; -.
OrthoDB; EOG091G11NF; -.
TreeFam; TF338524; -.
Proteomes; UP000002277; Chromosome 11.
Bgee; ENSPTRG00000003489; -.
GO; GO:0009986; C:cell surface; IBA:GO_Central.
GO; GO:0005576; C:extracellular region; IBA:GO_Central.
GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
GO; GO:0001848; F:complement binding; IBA:GO_Central.
GO; GO:0001775; P:cell activation; IBA:GO_Central.
GO; GO:0007166; P:cell surface receptor signaling pathway; IBA:GO_Central.
GO; GO:0001971; P:negative regulation of activation of membrane attack complex; IEA:InterPro.
GO; GO:0030449; P:regulation of complement activation; IBA:GO_Central.
InterPro; IPR018363; CD59_antigen_CS.
InterPro; IPR027101; CD59_glyco.
InterPro; IPR016054; LY6_UPA_recep-like.
PANTHER; PTHR10036:SF9; PTHR10036:SF9; 1.
Pfam; PF00021; UPAR_LY6; 1.
SMART; SM00134; LU; 1.
PROSITE; PS00983; LY6_UPAR; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000002277};
Reference proteome {ECO:0000313|Proteomes:UP000002277};
Signal {ECO:0000256|SAM:SignalP}.
SIGNAL 1 25 {ECO:0000256|SAM:SignalP}.
CHAIN 26 130 {ECO:0000256|SAM:SignalP}.
/FTId=PRO_5014149363.
SEQUENCE 130 AA; 14554 MW; 0BF2D02B0FD9B9F2 CRC64;
MGIQGGSVLF GLLLVLAVFC HSGHSLQCYN CPNPTADCKT AVNCSSDFDA CLITKAGLQV
YNKCWKLEHC NFKDLTTRLR ENELTYYCCK KDLCNFNEQL ENGGNEQLEN EKTVLLRVTP
FLAAAWSLHP


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