Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

CD99 antigen (Paired immunoglobin-like type 2 receptor-ligand) (PILR-L) (CD antigen CD99)

 CD99_MOUSE              Reviewed;         175 AA.
Q8VCN6; Q4L299; Q4L2A4; Q8BLN1;
07-MAR-2006, integrated into UniProtKB/Swiss-Prot.
01-MAR-2002, sequence version 1.
23-MAY-2018, entry version 73.
RecName: Full=CD99 antigen;
AltName: Full=Paired immunoglobin-like type 2 receptor-ligand;
Short=PILR-L;
AltName: CD_antigen=CD99;
Flags: Precursor;
Name=Cd99; Synonyms=Pilrl;
Mus musculus (Mouse).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
NCBI_TaxID=10090;
[1]
NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, AND INTERACTION WITH
PILRB.
PubMed=14970179; DOI=10.1084/jem.20031885;
Shiratori I., Ogasawara K., Saito T., Lanier L.L., Arase H.;
"Activation of natural killer cells and dendritic cells upon
recognition of a novel CD99-like ligand by paired immunoglobulin-like
type 2 receptor.";
J. Exp. Med. 199:525-533(2004).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], AND SUBUNIT.
TISSUE=Testis;
PubMed=15978751; DOI=10.1016/j.gene.2005.04.023;
Park S.H., Shin Y.K., Suh Y.H., Park W.S., Ban Y.L., Choi H.S.,
Park H.J., Jung K.C.;
"Rapid divergency of rodent CD99 orthologs: implications for the
evolution of the pseudoautosomal region.";
Gene 353:177-188(2005).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=C57BL/6J; TISSUE=Brain cortex;
PubMed=16141072; DOI=10.1126/science.1112014;
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M.,
Davis M.J., Wilming L.G., Aidinis V., Allen J.E.,
Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L.,
Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M.,
Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R.,
Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G.,
di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G.,
Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M.,
Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N.,
Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T.,
Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H.,
Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K.,
Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J.,
Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L.,
Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K.,
Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P.,
Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O.,
Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G.,
Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M.,
Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B.,
Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K.,
Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A.,
Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K.,
Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C.,
Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J.,
Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y.,
Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T.,
Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N.,
Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N.,
Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S.,
Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J.,
Hayashizaki Y.;
"The transcriptional landscape of the mammalian genome.";
Science 309:1559-1563(2005).
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=FVB/N; TISSUE=Colon;
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
[5]
FUNCTION, AND TISSUE SPECIFICITY.
PubMed=15280198; DOI=10.1182/blood-2004-03-1184;
Bixel G., Kloep S., Butz S., Petri B., Engelhardt B., Vestweber D.;
"Mouse CD99 participates in T-cell recruitment into inflamed skin.";
Blood 104:3205-3213(2004).
[6]
FUNCTION.
PubMed=20479283; DOI=10.1182/blood-2009-12-256388;
Bixel M.G., Li H., Petri B., Khandoga A.G., Khandoga A., Zarbock A.,
Wolburg-Buchholz K., Wolburg H., Sorokin L., Zeuschner D., Maerz S.,
Butz S., Krombach F., Vestweber D.;
"CD99 and CD99L2 act at the same site as, but independently of, PECAM-
1 during leukocyte diapedesis.";
Blood 116:1172-1184(2010).
-!- FUNCTION: Involved in T-cell adhesion processes. Plays a role in a
late step of leukocyte extravasation helping leukocytes to
overcome the endothelial basement membrane. Acts at the same site
as, but independently of, PECAM1. {ECO:0000269|PubMed:15280198,
ECO:0000269|PubMed:20479283}.
-!- SUBUNIT: Homodimer. Interacts with PILRB.
{ECO:0000269|PubMed:14970179, ECO:0000269|PubMed:15978751}.
-!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
membrane protein {ECO:0000305}.
-!- TISSUE SPECIFICITY: Widely expressed with high levels in lung,
spleen, thymus, liver and spinal chord. Expressed on leukocytes
and endothelial cell contacts. Detected in a wide range of T-
cells, including CD4-/CD8- and CD4+/CD8+ thymocytes. Expression is
much lower in peripheral T-cells than in thymocytes.
{ECO:0000269|PubMed:14970179, ECO:0000269|PubMed:15280198}.
-!- SIMILARITY: Belongs to the CD99 family. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; AY262359; AAP91691.1; -; Genomic_DNA.
EMBL; AY262355; AAP91687.1; -; mRNA.
EMBL; AK044051; BAC31754.1; -; mRNA.
EMBL; BC019482; AAH19482.1; -; mRNA.
RefSeq; NP_079860.2; NM_025584.2.
UniGene; Mm.423040; -.
SMR; Q8VCN6; -.
IntAct; Q8VCN6; 2.
PhosphoSitePlus; Q8VCN6; -.
MaxQB; Q8VCN6; -.
PRIDE; Q8VCN6; -.
GeneID; 673094; -.
KEGG; mmu:673094; -.
CTD; 4267; -.
MGI; MGI:1913728; Cd99.
InParanoid; Q8VCN6; -.
KO; K06520; -.
PRO; PR:Q8VCN6; -.
Proteomes; UP000000589; Unplaced.
CleanEx; MM_CD99; -.
GO; GO:0009986; C:cell surface; IDA:MGI.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005886; C:plasma membrane; TAS:Reactome.
GO; GO:0034109; P:homotypic cell-cell adhesion; IDA:MGI.
GO; GO:0001773; P:myeloid dendritic cell activation; IDA:MGI.
GO; GO:2000391; P:positive regulation of neutrophil extravasation; IMP:MGI.
GO; GO:0072683; P:T cell extravasation; IMP:MGI.
InterPro; IPR022078; CD99L2.
PANTHER; PTHR15076; PTHR15076; 1.
Pfam; PF12301; CD99L2; 1.
1: Evidence at protein level;
Complete proteome; Membrane; Reference proteome; Signal;
Transmembrane; Transmembrane helix.
SIGNAL 1 28 {ECO:0000255}.
CHAIN 29 175 CD99 antigen.
/FTId=PRO_0000226820.
TOPO_DOM 29 137 Extracellular. {ECO:0000255}.
TRANSMEM 138 158 Helical. {ECO:0000255}.
TOPO_DOM 159 175 Cytoplasmic. {ECO:0000255}.
CONFLICT 100 100 D -> G (in Ref. 3; BAC31754).
{ECO:0000305}.
CONFLICT 111 111 Missing (in Ref. 2; AAP91687/AAP91691 and
3; BAC31754). {ECO:0000305}.
CONFLICT 114 114 R -> P (in Ref. 2; AAP91687/AAP91691).
{ECO:0000305}.
CONFLICT 128 128 G -> R (in Ref. 2; AAP91687).
{ECO:0000305}.
CONFLICT 148 149 AA -> PP (in Ref. 3; BAC31754).
{ECO:0000305}.
SEQUENCE 175 AA; 16783 MW; A309E6E2494FBFE1 CRC64;
MARAAMEAAA TVVLALALLG AAARGAASDD FNLGDALEDP NMKPTPKAPT PKKPSGGFDL
EDALPGGGGG GAGEKPGNRP QPDPKPPRPH GDSGGISDSD LADAAGQGGG GAGRRGSGDE
GGHGGAGGAE PEGTPQGLVP GVVAAVVAAV AGAVSSFVAY QRRRLCFREG GSAPV


Related products :

Catalog number Product name Quantity
EIAAB06411 Cd99,CD99 antigen,Mouse,Mus musculus,Paired immunoglobin-like type 2 receptor-ligand,Pilrl,PILR-L
CD99-101AP CD99 Antigen , CD99-1 Antigenic peptide: P-CD99-100 Host: Rabbit Affinity purifed 100ul
CD99-112AP CD99 Antigen , CD99-2 Antigenic peptide: P-CD99-110 Host: Rabbit Affinity purifed 100ul
CD99-101AP CD99 Antigen , CD99-1 WB control: PC-CD99 Host: Rabbit Affinity purifed 100-150ul
CD99-112AP CD99 Antigen , CD99-2 WB control: PC-CD99 Host: Rabbit Affinity purifed 100-150ul
CD99-112AP CD99 Antigen , CD99-2 Biotin Conjugates: CD99-110-Biotin Host: Rabbit Affinity purifed 200ul
CD99-101AP CD99 Antigen , CD99-1 FITC-conjugates: CD99-100-FITC Host: Rabbit Affinity purifed 200ul
CD99-101AP CD99 Antigen , CD99-1 Biotin Conjugates: CD99-100-Biotin Host: Rabbit Affinity purifed 200ul
CD99-112AP CD99 Antigen , CD99-2 FITC-conjugates: CD99-110-FITC Host: Rabbit Affinity purifed 200ul
CD99-101AP CD99 Antigen , CD99-1 Polyclonal anbtibody Host: Rabbit Affinity purifed 200ul
CD99-112AP CD99 Antigen , CD99-2 Polyclonal anbtibody Host: Rabbit Affinity purifed 200ul
EIAAB06412 12E7,CD99,CD99 antigen,E2 antigen,Homo sapiens,Human,MIC2,MIC2X,MIC2Y,Protein MIC2,T-cell surface glycoprotein E2
CD99_HUMAN ELISA Kit FOR CD99 antigen; organism: Human; gene name: CD99 96T
CD99_MOUSE ELISA Kit FOR CD99 antigen; organism: Mouse; gene name: Cd99 96T
20-783-71192 MOUSE ANTI HUMAN CD99 - MIC2; CD99 antigen. isoform CRA_a Monoclonal 0.1 ml
20-783-71191 MOUSE ANTI HUMAN CD99 - MIC2; CD99 antigen. isoform CRA_a Monoclonal 6 ml
20-783-71190 MOUSE ANTI HUMAN CD99 - MIC2; CD99 antigen. isoform CRA_a Monoclonal 1 ml
20-783-71058 MOUSE ANTI HUMAN CD99 - MIC2; CD99 antigen. isoform CRA_a Monoclonal 0.2 mg
CSB-EL004973HU Human CD99 antigen(CD99) ELISA kit SpeciesHuman 96T
CSB-EL004973MO Mouse CD99 antigen(CD99) ELISA kit SpeciesMouse 96T
20-783-71059 MOUSE ANTI HUMAN CD99 FITC - MIC2; CD99 antigen. isoform CRA_a Monoclonal 0.1 mg
CSB-EL004973MO Mouse CD99 antigen(CD99) ELISA kit 96T
CSB-EL004973HU Human CD99 antigen(CD99) ELISA kit 96T
Cd99-3262M Recombinant Mouse CD99 Antigen, Fc Chimera species: Mouse 100
LF-PA40236 anti-CD99 Molecule (CD99) , Rabbit polyclonal to CD99 Molecule (CD99) , Isotype IgG, Host Rabbit 50 ug


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur