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CDX2/AS

 A0A076MKN9_HUMAN        Unreviewed;       271 AA.
A0A076MKN9;
29-OCT-2014, integrated into UniProtKB/TrEMBL.
29-OCT-2014, sequence version 1.
30-AUG-2017, entry version 10.
SubName: Full=CDX2/AS {ECO:0000313|EMBL:AIJ19452.1};
Name=CDX2 {ECO:0000313|EMBL:AIJ19452.1};
Homo sapiens (Human).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
NCBI_TaxID=9606 {ECO:0000313|EMBL:AIJ19452.1};
[1] {ECO:0000313|EMBL:AIJ19452.1}
NUCLEOTIDE SEQUENCE.
TISSUE=Colorectal tumor {ECO:0000313|EMBL:AIJ19452.1};
PubMed=25101906;
Witek M.E., Snook A.E., Lin J.E., Blomain E.S., Xiang B., Magee M.,
Waldman S.A.;
"A Novel CDX2 Isoform Regulates Alternative Splicing.";
PLoS ONE 9:E104293-E104293(2014).
-!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-
ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
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EMBL; KJ081251; AIJ19452.1; -; mRNA.
UniGene; Hs.127383; -.
UniGene; Hs.174249; -.
UniGene; Hs.740844; -.
PeptideAtlas; A0A076MKN9; -.
GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO; GO:0007275; P:multicellular organism development; IEA:InterPro.
GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
InterPro; IPR006820; Caudal_activation_dom.
InterPro; IPR009057; Homeobox-like.
InterPro; IPR001356; Homeobox_dom.
Pfam; PF04731; Caudal_act; 1.
Pfam; PF00046; Homeobox; 1.
SMART; SM00389; HOX; 1.
SUPFAM; SSF46689; SSF46689; 1.
PROSITE; PS50071; HOMEOBOX_2; 1.
2: Evidence at transcript level;
DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
ECO:0000256|RuleBase:RU000682};
Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
ECO:0000256|RuleBase:RU000682};
Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
ECO:0000256|RuleBase:RU000682}.
DOMAIN 182 242 Homeobox DNA-binding.
{ECO:0000259|PROSITE:PS50071}.
DNA_BIND 184 243 Homeobox. {ECO:0000256|PROSITE-
ProRule:PRU00108}.
SEQUENCE 271 AA; 29334 MW; C71EF8AC0228CD26 CRC64;
MYVSYLLDKD VSMYPSSVRH SGGLNLAPQN FVSPPQYPDY GGYHVAAAAA AQNLDSAQSP
GPSWPAAYGA PLREDWNGYA PGGAAAANAV AHALNGGSPA AAMGYSSPAD YHPHHHPHHH
PHHPAAAPSC ASGLLQTLNP GPPGPAATAA AEQLSPGGQR RNLCEWMRKP AQQSLGSQVK
TRTKDKYRVV YTDHQRLELE KEFHYSRYIT IRRKAELAAT LGLSERLKSG FRTAEQRRGK
STRRSCSSNS SSSHHSRLRR HHSLPSLSQV L


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