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CTP synthase (EC 6.3.4.2) (Cytidine 5'-triphosphate synthase) (Cytidine triphosphate synthetase) (CTP synthetase) (CTPS) (UTP--ammonia ligase)

 C3SX67_ECOLX            Unreviewed;       545 AA.
C3SX67; A0A0J3VST7;
16-JUN-2009, integrated into UniProtKB/TrEMBL.
16-JUN-2009, sequence version 1.
22-NOV-2017, entry version 80.
RecName: Full=CTP synthase {ECO:0000256|HAMAP-Rule:MF_01227};
EC=6.3.4.2 {ECO:0000256|HAMAP-Rule:MF_01227};
AltName: Full=Cytidine 5'-triphosphate synthase {ECO:0000256|HAMAP-Rule:MF_01227};
AltName: Full=Cytidine triphosphate synthetase {ECO:0000256|HAMAP-Rule:MF_01227};
Short=CTP synthetase {ECO:0000256|HAMAP-Rule:MF_01227};
Short=CTPS {ECO:0000256|HAMAP-Rule:MF_01227};
AltName: Full=UTP--ammonia ligase {ECO:0000256|HAMAP-Rule:MF_01227};
Name=pyrG {ECO:0000256|HAMAP-Rule:MF_01227,
ECO:0000313|EMBL:AIX64615.1};
ORFNames=A4T40_19125 {ECO:0000313|EMBL:ORD26430.1},
A8M42_16405 {ECO:0000313|EMBL:OWE30460.1},
A8M44_05675 {ECO:0000313|EMBL:OWD95226.1},
A8M71_18575 {ECO:0000313|EMBL:OWF13778.1},
A8M72_17825 {ECO:0000313|EMBL:OWE90906.1},
A8M81_05290 {ECO:0000313|EMBL:OWC08691.1},
A9R57_06965 {ECO:0000313|EMBL:OEI65690.1},
A9X62_00570 {ECO:0000313|EMBL:OWF28898.1},
AA102_05735 {ECO:0000313|EMBL:AKH23448.1},
AC067_22330 {ECO:0000313|EMBL:KOA27540.1},
AC789_1c31020 {ECO:0000313|EMBL:AJE57317.1},
ACN002_2797 {ECO:0000313|EMBL:ALY14255.1},
ACN77_07080 {ECO:0000313|EMBL:OKU14394.1},
ACN81_20385 {ECO:0000313|EMBL:OKU18502.1},
ACU57_24415 {ECO:0000313|EMBL:KPO04853.1},
ACU90_23015 {ECO:0000313|EMBL:KPO46814.1},
AKG99_03555 {ECO:0000313|EMBL:KOA00539.1},
AKN40_1033 {ECO:0000313|EMBL:ASO77854.1},
AM266_20155 {ECO:0000313|EMBL:KQJ12937.1},
AM270_00945 {ECO:0000313|EMBL:KQJ46203.1},
AM375_08825 {ECO:0000313|EMBL:ARX55331.1},
AML07_12460 {ECO:0000313|EMBL:KYR52215.1},
AML35_05300 {ECO:0000313|EMBL:KYS97943.1},
APT94_17890 {ECO:0000313|EMBL:KSY01530.1},
APU18_18535 {ECO:0000313|EMBL:KSZ14044.1},
APZ14_09290 {ECO:0000313|EMBL:KST32189.1},
ARC77_10140 {ECO:0000313|EMBL:AMW42571.1},
AU473_08010 {ECO:0000313|EMBL:APA40841.1},
AUQ13_17535 {ECO:0000313|EMBL:KXR89032.1},
AUS26_15660 {ECO:0000313|EMBL:KXL60459.1},
AW059_10675 {ECO:0000313|EMBL:OTB39597.1},
AW106_00665 {ECO:0000313|EMBL:OTE03079.1},
AWP75_20610 {ECO:0000313|EMBL:OKW14748.1},
AZZ83_003241 {ECO:0000313|EMBL:OUG25243.1},
B1K96_20050 {ECO:0000313|EMBL:OTE91503.1},
B7C53_10055 {ECO:0000313|EMBL:OWS85717.1},
BE932_11855 {ECO:0000313|EMBL:AQV73106.1},
BE957_08855 {ECO:0000313|EMBL:AQV19272.1},
BE963_03670 {ECO:0000313|EMBL:AQV28759.1},
BET08_07180 {ECO:0000313|EMBL:ONK53673.1},
BHF46_05050 {ECO:0000313|EMBL:OEN36434.1},
BHS80_15395 {ECO:0000313|EMBL:OWX90458.1},
BHS81_16640 {ECO:0000313|EMBL:ORJ75828.1},
BHS87_15735 {ECO:0000313|EMBL:ORT01698.1},
BIQ87_15835 {ECO:0000313|EMBL:OWX81492.1},
BJJ90_05265 {ECO:0000313|EMBL:APT01472.1},
BK248_12970 {ECO:0000313|EMBL:OJK74940.1},
BK292_23205 {ECO:0000313|EMBL:OJM88468.1},
BK334_11935 {ECO:0000313|EMBL:OJP14027.1},
BK373_15870 {ECO:0000313|EMBL:OJR03376.1},
BK375_10085 {ECO:0000313|EMBL:OJR16488.1},
BK383_11680 {ECO:0000313|EMBL:OJR54730.1},
BK400_05820 {ECO:0000313|EMBL:OJS90484.1},
BMT49_17330 {ECO:0000313|EMBL:OKB79943.1},
BMT53_21250 {ECO:0000313|EMBL:OKB91852.1},
BMT91_11105 {ECO:0000313|EMBL:OOK28426.1},
BMT94_18550 {ECO:0000313|EMBL:OOJ04544.1},
BMT97_03125 {ECO:0000313|EMBL:OOJ23562.1},
BN17_26661 {ECO:0000313|EMBL:CCJ45363.1},
BUE81_06975 {ECO:0000313|EMBL:OLR88165.1},
BUE82_04385 {ECO:0000313|EMBL:APT61250.1},
BW690_04975 {ECO:0000313|EMBL:ONG31077.1},
BWP17_05185 {ECO:0000313|EMBL:OOC83858.1},
BXT93_24405 {ECO:0000313|EMBL:ONG29123.1},
BZL31_00820 {ECO:0000313|EMBL:OUK55296.1},
BZL33_15640 {ECO:0000313|EMBL:OUK51179.1},
BZL69_02125 {ECO:0000313|EMBL:OUL00379.1},
CA268_23715 {ECO:0000313|EMBL:ARR62155.1},
CA270_09940 {ECO:0000313|EMBL:ARR65179.1},
CA593_12975 {ECO:0000313|EMBL:ARR33953.1},
CA947_03565 {ECO:0000313|EMBL:OWY56979.1},
CCL28_05770 {ECO:0000313|EMBL:ASA41638.1},
CDL37_13440 {ECO:0000313|EMBL:OXK51756.1},
CDL44_17565 {ECO:0000313|EMBL:OXK10256.1},
CDL49_13530 {ECO:0000313|EMBL:OXJ81029.1},
CDL57_20625 {ECO:0000313|EMBL:OXV13648.1},
CES94_05830 {ECO:0000313|EMBL:ASG48521.1},
CI718_20755 {ECO:0000313|EMBL:OYK37181.1},
EC3234A_48c00890 {ECO:0000313|EMBL:OAC43282.1},
ECONIH1_15890 {ECO:0000313|EMBL:AIX64615.1},
ECs3640 {ECO:0000313|EMBL:ACI79056.1},
EL75_0914 {ECO:0000313|EMBL:KGM71258.1},
EL79_0915 {ECO:0000313|EMBL:KGM84781.1},
EL80_0918 {ECO:0000313|EMBL:KGM83222.1},
ERS085365_02427 {ECO:0000313|EMBL:CTS74713.1},
ERS085366_03042 {ECO:0000313|EMBL:CTT27611.1},
ERS085374_03279 {ECO:0000313|EMBL:CTS03443.1},
ERS085386_03410 {ECO:0000313|EMBL:CTU02464.1},
ERS085416_02898 {ECO:0000313|EMBL:CTW24677.1},
ERS139211_02072 {ECO:0000313|EMBL:CTV91638.1},
ERS150873_02003 {ECO:0000313|EMBL:CTZ37548.1},
ERS150876_01467 {ECO:0000313|EMBL:CTZ62786.1},
FORC28_1110 {ECO:0000313|EMBL:AOM44101.1},
GJ11_18025 {ECO:0000313|EMBL:ANO90585.1},
GJ12_17995 {ECO:0000313|EMBL:ANP19578.1},
HMPREF3040_01161 {ECO:0000313|EMBL:KXH01378.1},
HW42_18535 {ECO:0000313|EMBL:AIZ83819.1},
JD73_16335 {ECO:0000313|EMBL:KFD75255.1},
MJ49_17095 {ECO:0000313|EMBL:ALL89202.1},
MS6198_30910 {ECO:0000313|EMBL:AOM71148.1},
PGD_04325 {ECO:0000313|EMBL:CDU41322.1},
PU06_02080 {ECO:0000313|EMBL:KHJ23402.1},
RG28_07675 {ECO:0000313|EMBL:APJ76174.1},
SK85_03024 {ECO:0000313|EMBL:KLX95482.1},
SM09_02917 {ECO:0000313|EMBL:KME68389.1},
SY51_15605 {ECO:0000313|EMBL:AJO84759.1},
UC41_20365 {ECO:0000313|EMBL:KJH05916.1},
UN91_03645 {ECO:0000313|EMBL:KJW53122.1},
WM48_14990 {ECO:0000313|EMBL:ANK33519.1},
WQ89_10170 {ECO:0000313|EMBL:KNF80526.1},
WR15_06090 {ECO:0000313|EMBL:KNF70809.1};
Escherichia coli.
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
Enterobacteriaceae; Escherichia.
NCBI_TaxID=562 {ECO:0000313|EMBL:ACI79056.1};
[1] {ECO:0000313|EMBL:ACI79056.1}
NUCLEOTIDE SEQUENCE.
STRAIN=493/89 {ECO:0000313|EMBL:ACI79056.1},
86-24 {ECO:0000313|EMBL:ACI79057.1},
87-14 {ECO:0000313|EMBL:ACI79058.1}, and
TW14359 {ECO:0000313|EMBL:ACI79060.1};
PubMed=19439656; DOI=10.1073/pnas.0812949106;
Leopold S.R., Magrini V., Holt N.J., Shaikh N., Mardis E.R., Cagno J.,
Ogura Y., Iguchi A., Hayashi T., Mellmann A., Karch H., Besser T.E.,
Sawyer S.A., Whittam T.S., Tarr P.I.;
"A precise reconstruction of the emergence and constrained radiations
of Escherichia coli O157 portrayed by backbone concatenomic
analysis.";
Proc. Natl. Acad. Sci. U.S.A. 106:8713-8718(2009).
[2] {ECO:0000313|EMBL:CCJ45363.1}
NUCLEOTIDE SEQUENCE.
STRAIN=IMT2125 {ECO:0000313|EMBL:CCJ45363.1};
Lim C.-J.;
Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
[3] {ECO:0000313|EMBL:CCJ45363.1, ECO:0000313|Proteomes:UP000094022}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=IMT2125 {ECO:0000313|EMBL:CCJ45363.1,
ECO:0000313|Proteomes:UP000094022};
PubMed=23275093; DOI=10.1128/IAI.00585-12;
Dziva F., Hauser H., Connor T.R., van Diemen P.M., Prescott G.,
Langridge G.C., Eckert S., Chaudhuri R.R., Ewers C., Mellata M.,
Mukhopadhyay S., Curtiss R., Dougan G., Wieler L.H., Thomson N.R.,
Pickard D.J., Stevens M.P.;
"Sequencing and functional annotation of avian pathogenic Escherichia
coli serogroup O78 strains reveal the evolution of E. coli lineages
pathogenic for poultry via distinct mechanisms.";
Infect. Immun. 81:838-849(2013).
[4] {ECO:0000313|EMBL:AIX64615.1, ECO:0000313|Proteomes:UP000030317}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ECONIH1 {ECO:0000313|EMBL:AIX64615.1,
ECO:0000313|Proteomes:UP000030317};
PubMed=25232178;
NISC Comparative Sequencing Program;
Conlan S., Thomas P.J., Deming C., Park M., Lau A.F., Dekker J.P.,
Snitkin E.S., Clark T.A., Luong K., Song Y., Tsai Y.C., Boitano M.,
Dayal J., Brooks S.Y., Schmidt B., Young A.C., Thomas J.W.,
Bouffard G.G., Blakesley R.W., Mullikin J.C., Korlach J.,
Henderson D.K., Frank K.M., Palmore T.N., Segre J.A.;
"Single-molecule sequencing to track plasmid diversity of hospital-
associated carbapenemase-producing Enterobacteriaceae.";
Sci. Transl. Med. 6:254RA126-254RA126(2014).
[5] {ECO:0000313|EMBL:ALY14255.1, ECO:0000313|Proteomes:UP000066343}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ACN002 {ECO:0000313|EMBL:ALY14255.1,
ECO:0000313|Proteomes:UP000066343};
Wei L., Wang X., Wang B.;
"Complete genome sequence of Avian pathogenic Escherichia coli strain
ACN002.";
Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
[6] {ECO:0000313|EMBL:CDU41322.1}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=D6-117_07.11 {ECO:0000313|EMBL:CDU41322.1};
Kempf F., Loux V., Germon P.;
"Genome sequence of four bovine mastitis-causing Escherichia coli
strains.";
Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
[7] {ECO:0000313|EMBL:KGM83222.1, ECO:0000313|Proteomes:UP000030018}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=G8 {ECO:0000313|EMBL:KGM83222.1,
ECO:0000313|Proteomes:UP000030018};
Zschuettig A., Auerbach C., Meltke S., Eichhorn C., Brandt M.,
Blom J., Goesmann A., Jarek M., Scharfe M., Zimmermann K.,
Wassenaar T.M., Gunzer F.;
"Complete sequence of probiotic Symbioflor2 E. coli G3/10 and draft
sequences of Symbioflor2 strains G1/2, G4/9, G5, G6/7 and G8.";
Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
[8] {ECO:0000313|EMBL:KGM71258.1, ECO:0000313|Proteomes:UP000029988, ECO:0000313|Proteomes:UP000030000}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=G1/2 {ECO:0000313|EMBL:KGM71258.1,
ECO:0000313|Proteomes:UP000030000}, and
G6/7 {ECO:0000313|EMBL:KGM84781.1, ECO:0000313|Proteomes:UP000029988};
Zschuettig A., Auerbach C., Meltke S., Eichhorn C., Brandt M.,
Blom J., Goesmann A., Jarek M., Scharfe M., Zimmermann K.,
Wassenaar T.M., Gunzer F.;
"Complete sequence of probiotic Symbioflor2 E. coli strain G3/10 and
draft sequences of Symbioflor2 strains G1/2, G4/9, G5, G6/7 and G8.";
Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
[9] {ECO:0000313|EMBL:KFD75255.1, ECO:0000313|Proteomes:UP000028651}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=48 {ECO:0000313|EMBL:KFD75255.1,
ECO:0000313|Proteomes:UP000028651};
Nuesch-Inderbinen M.T., Funk J., Cernela N., Tasara T., Klumpp J.,
Schmidt H., Stephan R.;
"Prevalence of subtilase cytotoxin-encoding subAB variants among Shiga
toxin-producing Escherichia coli strains isolated from wild ruminants
and sheep differs from that of cattle and pigs and is predominated by
the new allelic variant subAB2-2.";
Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
[10] {ECO:0000313|EMBL:APJ76174.1, ECO:0000313|Proteomes:UP000184379}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=C5 {ECO:0000313|EMBL:APJ76174.1,
ECO:0000313|Proteomes:UP000184379};
Jiang J., Xu Z., Zhou Y., Zhao H., Leung F.C.C.;
"Vertical and Horizontal Evolutionary Story implied from E. coli
complete genomes.";
Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
[11] {ECO:0000313|EMBL:KHJ23402.1, ECO:0000313|Proteomes:UP000030834}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CVM N33561PS {ECO:0000313|EMBL:KHJ23402.1,
ECO:0000313|Proteomes:UP000030834};
Tyson G.H., McDermott P.F., Li C., Tadesse D.A., Mukherjee S.,
Bodeis-Jones S., Kabera C., Gaines S.A., Loneragan G.H.,
Edrington T.S., Torrence M., Harhay D.M., Zhao S.;
"Whole-genome sequencing effectively predicts antimicrobial resistance
phenotypes of E. coli.";
Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
[12] {ECO:0000313|EMBL:AJO84759.1}
NUCLEOTIDE SEQUENCE.
STRAIN=MNCRE44 {ECO:0000313|EMBL:AJO84759.1};
PubMed=26438492; DOI=10.1128/AAC.01291-15;
Hargreaves M.L., Shaw K.M., Dobbins G., Snippes Vagnone P.M.,
Harper J.E., Boxrud D., Lynfield R., Aziz M., Price L.B.,
Silverstein K.A., Danzeisen J.L., Youmans B., Case K., Sreevatsan S.,
Johnson T.J.;
"Clonal Dissemination of Enterobacter cloacae Harboring blaKPC-3 in
the Upper Midwestern United States.";
Antimicrob. Agents Chemother. 59:7723-7734(2015).
[13] {ECO:0000313|EMBL:AIZ83819.1, ECO:0000313|Proteomes:UP000030790}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=RM9387 {ECO:0000313|EMBL:AIZ83819.1,
ECO:0000313|Proteomes:UP000030790};
PubMed=25887577; DOI=10.1186/s12866-015-0413-9;
Yan X., Fratamico P.M., Bono J.L., Baranzoni G.M., Chen C.Y.;
"Genome sequencing and comparative genomics provides insights on the
evolutionary dynamics and pathogenic potential of different H-
serotypes of Shiga toxin-producing Escherichia coli O104.";
BMC Microbiol. 15:83-83(2015).
[14] {ECO:0000313|EMBL:KPO04853.1, ECO:0000313|Proteomes:UP000050307, ECO:0000313|Proteomes:UP000050556}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=09-0523 {ECO:0000313|EMBL:KPO46814.1,
ECO:0000313|Proteomes:UP000050307}, and
AW1.3 {ECO:0000313|EMBL:KPO04853.1,
ECO:0000313|Proteomes:UP000050556};
PubMed=26441869; DOI=10.3389/fmicb.2015.00932;
Mercer R.G., Zheng J., Garcia-Hernandez R., Ruan L., Ganzle M.G.,
McMullen L.M.;
"Genetic determinants of heat resistance in Escherichia coli.";
Front. Microbiol. 6:932-932(2015).
[15] {ECO:0000313|EMBL:AKH23448.1}
NUCLEOTIDE SEQUENCE.
STRAIN=CFSAN029787 {ECO:0000313|EMBL:AKH23448.1};
PubMed=26251502;
Pettengill E.A., Hoffmann M., Binet R., Roberts R.J., Payne J.,
Allard M., Michelacci V., Minelli F., Morabito S.;
"Complete Genome Sequence of Enteroinvasive Escherichia coli O96:H19
Associated with a Severe Foodborne Outbreak.";
Genome Announc. 3:e00883-15(2015).
[16] {ECO:0000313|EMBL:ALL89202.1, ECO:0000313|Proteomes:UP000065978}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=2009C-3133 {ECO:0000313|EMBL:ALL89202.1,
ECO:0000313|Proteomes:UP000065978};
PubMed=26679598;
Lindsey R.L., Knipe K., Rowe L., Garcia-Toledo L., Loparev V.,
Juieng P., Trees E., Strockbine N., Stripling D., Gerner-Smidt P.;
"Complete Genome Sequences of Two Shiga Toxin-Producing Escherichia
coli Strains from Serotypes O119:H4 and O165:H25.";
Genome Announc. 3:e01496-15(2015).
[17] {ECO:0000313|EMBL:AJO84759.1, ECO:0000313|Proteomes:UP000032290}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=MNCRE44 {ECO:0000313|EMBL:AJO84759.1,
ECO:0000313|Proteomes:UP000032290};
PubMed=25858844;
Johnson T.J., Hargreaves M., Shaw K., Snippes P., Lynfield R.,
Aziz M., Price L.B.;
"Complete Genome Sequence of a Carbapenem-Resistant Extraintestinal
Pathogenic Escherichia coli Strain Belonging to the Sequence Type 131
H30R Subclade.";
Genome Announc. 3:0-0(2015).
[18] {ECO:0000313|Proteomes:UP000031522}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=789 {ECO:0000313|Proteomes:UP000031522};
Huja S., Oren Y., Trost E., Brzuszkiewicz E., Biran D., Blom J.,
Goesmann A., Gottschalk G., Hacker J., Ron E.Z., Dobrindt U.;
"Genomic Avenue to Avian Colisepticemia.";
MBio 6:e01681-14(2015).
[19] {ECO:0000313|EMBL:AJE57317.1}
NUCLEOTIDE SEQUENCE.
STRAIN=789 {ECO:0000313|EMBL:AJE57317.1};
PubMed=25587010;
Huja S., Oren Y., Trost E., Brzuszkiewicz E., Biran D., Blom J.,
Goesmann A., Gottschalk G., Hacker J., Ron E.Z., Dobrindt U.;
"Genomic avenue to avian colisepticemia.";
MBio 6:0-0(2015).
[20] {ECO:0000313|EMBL:OAC43282.1, ECO:0000313|Proteomes:UP000077380}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=3234/A {ECO:0000313|EMBL:OAC43282.1,
ECO:0000313|Proteomes:UP000077380};
Leimbach A., Poehlein A., Daniel R., Dobrindt U.;
"Comparative genomics of E. coli bovine mastitis and fecal commensal
isolates.";
Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
[21] {ECO:0000313|EMBL:KJH05916.1, ECO:0000313|Proteomes:UP000032456}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=D2-2 {ECO:0000313|EMBL:KJH05916.1,
ECO:0000313|Proteomes:UP000032456};
Olsen R.H., Bisgaard M., Christensen J.P., Christensen H., Thofner I.,
Pors S.E.;
"Genome sequence of Escherichia coli strain D2-2.";
Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
[22] {ECO:0000313|EMBL:KJW53122.1, ECO:0000313|Proteomes:UP000033371}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=St. Olav173 {ECO:0000313|EMBL:KJW53122.1,
ECO:0000313|Proteomes:UP000033371};
Gabrielsen C., Drablos F., Afset J.E.;
"Genome sequences of 11 non-O157 Shiga Toxin-Producing Escherichia
coli strains.";
Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
[23] {ECO:0000313|Proteomes:UP000034530}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CFSAN029787 {ECO:0000313|Proteomes:UP000034530};
Timme R., Allard M.W., Strain E., Evans P.S., Brown E.;
"Whole genome shotgun sequencing of cultured foodborne pathogen.";
Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
[24] {ECO:0000313|EMBL:AKH23448.1}
NUCLEOTIDE SEQUENCE.
STRAIN=CFSAN029787 {ECO:0000313|EMBL:AKH23448.1};
Wang D.B., Wang M.;
Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
[25] {ECO:0000313|EMBL:KOA27540.1, ECO:0000313|Proteomes:UP000037153}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=FE95160 {ECO:0000313|EMBL:KOA27540.1,
ECO:0000313|Proteomes:UP000037153};
Nyholm O., Halkilahti J., Wiklund G., Okeke U., Paulin L., Auvinen P.,
Haukka K., Siitonen A.;
"Comparative genomics and characterization of hybrid Shigatoxigenic
and enterotoxigenic Escherichia coli (STEC/ETEC) strains.";
Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
[26] {ECO:0000313|EMBL:KLX95482.1, ECO:0000313|Proteomes:UP000036012, ECO:0000313|Proteomes:UP000036405}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=BIDMC112 {ECO:0000313|EMBL:KLX95482.1,
ECO:0000313|Proteomes:UP000036012}, and
CHS199 {ECO:0000313|EMBL:KME68389.1,
ECO:0000313|Proteomes:UP000036405};
The Broad Institute Genomics Platform;
The Broad Institute Genome Sequencing Center for Infectious Disease;
Earl A.M., Onderdonk A.B., Kirby J., Ferraro M.J., Huang S.,
Spencer M., Fodor A., Hooper D., Dekker J., O'Brien T., Quan V.,
Gombosev A., Delaney M., DuBois A., Ernst C., Kim D.S., Rossman W.,
Gohs F., Petruso H., Nozar T., Mougeot F., Manson-McGuire A.,
Young S., Abouelleil A., Cao P., Chapman S.B., Griggs A., Priest M.,
Shea T., Wortman I., Wortman J.R., Nusbaum C., Birren B.;
"The Genome Sequence of None.";
Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
[27] {ECO:0000313|EMBL:KOA00539.1, ECO:0000313|Proteomes:UP000036728}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=INSLA289 {ECO:0000313|EMBL:KOA00539.1,
ECO:0000313|Proteomes:UP000036728};
Jones-Dias D., Manageiro V., Sampaio D.A., Vieira L., Canica M.;
"Draft genome sequence of a pathogenic ST57 Escherichia coli from
poultry carrying twelve acquired antibiotic resistance genes.";
Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
[28] {ECO:0000313|EMBL:KNF70809.1, ECO:0000313|Proteomes:UP000036812, ECO:0000313|Proteomes:UP000037564}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CFSAN026817 {ECO:0000313|EMBL:KNF80526.1,
ECO:0000313|Proteomes:UP000036812}, and
CFSAN026843 {ECO:0000313|EMBL:KNF70809.1,
ECO:0000313|Proteomes:UP000037564};
Gonzalez-Escalona N., Toro M., Timme R., Payne J.;
"Genome sequences of 64 non-O157:H7 Shiga toxin-producing Escherichia
coli strains.";
Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
[29] {ECO:0000313|EMBL:KQJ12937.1, ECO:0000313|Proteomes:UP000051846, ECO:0000313|Proteomes:UP000051850}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=221 {ECO:0000313|EMBL:KQJ12937.1,
ECO:0000313|Proteomes:UP000051850}, and
304 {ECO:0000313|EMBL:KQJ46203.1, ECO:0000313|Proteomes:UP000051846};
Kudirkiene E., Olsen J.E.;
"Characterization of Escherichia coli strains isolated from cattle and
human in Tanzania.";
Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
[30] {ECO:0000313|EMBL:CTS03443.1}
NUCLEOTIDE SEQUENCE.
STRAIN=201589_aEPEC {ECO:0000313|EMBL:CTW24677.1},
400654_aEPEC {ECO:0000313|EMBL:CTU02464.1},
403728 {ECO:0000313|EMBL:CTV91638.1},
503028_aEPEC {ECO:0000313|EMBL:CTS74713.1},
503225_aEPEC {ECO:0000313|EMBL:CTT27611.1},
504888_aEPEC {ECO:0000313|EMBL:CTS03443.1},
G100788-1A {ECO:0000313|EMBL:CTZ62786.1}, and
G500830 {ECO:0000313|EMBL:CTZ37548.1};
Rikkerink E.H.A., Fineran P.C.;
"Complete DNA Sequence of Pseudomonas syringae pv. actinidiae, the
Causal Agent of Kiwifruit Canker Disease.";
Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
[31] {ECO:0000313|EMBL:ASO77854.1, ECO:0000313|Proteomes:UP000203621}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=MEM {ECO:0000313|EMBL:ASO77854.1,
ECO:0000313|Proteomes:UP000203621};
Liu B.;
"Domestication mutations in four distinct E. coli isolates are strain-
specific and environment dependent.";
Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
[32] {ECO:0000313|Proteomes:UP000038112, ECO:0000313|Proteomes:UP000040934, ECO:0000313|Proteomes:UP000041959}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=201589_aEPEC {ECO:0000313|Proteomes:UP000040934},
400654_aEPEC {ECO:0000313|Proteomes:UP000042887},
403728 {ECO:0000313|Proteomes:UP000044893},
503028_aEPEC {ECO:0000313|Proteomes:UP000041959},
503225_aEPEC {ECO:0000313|Proteomes:UP000045242},
504888_aEPEC {ECO:0000313|Proteomes:UP000038112},
G100788-1A {ECO:0000313|Proteomes:UP000044469}, and
G500830 {ECO:0000313|Proteomes:UP000042305};
Pathogen Informatics;
Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
[33] {ECO:0000313|EMBL:AOM44101.1, ECO:0000313|Proteomes:UP000094451}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=FORC_028 {ECO:0000313|EMBL:AOM44101.1,
ECO:0000313|Proteomes:UP000094451};
Jackson K.R., Lunt B.L., Fisher J.N.B., Gardner A.V., Bailey M.E.,
Deus L.M., Earl A.S., Gibby P.D., Hartmann K.A., Liu J.E., Manci A.M.,
Nielsen D.A., Solomon M.B., Breakwell D.P., Burnett S.H., Grose J.H.;
Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
[34] {ECO:0000313|Proteomes:UP000054864}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=22593 {ECO:0000313|Proteomes:UP000054864};
Valat C., Goldstone R.J., Hirchaud E., Haenni M., Smith D.G.,
Madec J.-Y.;
"Shiga toxin-producing Escherichia coli (STEC) encoding Extended-
Spectrum Beta-Lactamases (ESBLs) recovered from diarrheic cattle.";
Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
[35] {ECO:0000313|EMBL:KSY01530.1, ECO:0000313|Proteomes:UP000053450, ECO:0000313|Proteomes:UP000054277}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=50640492 {ECO:0000313|EMBL:KSY01530.1,
ECO:0000313|Proteomes:UP000054277}, and
50870281 {ECO:0000313|EMBL:KSZ14044.1,
ECO:0000313|Proteomes:UP000053450};
Millard Andrew;
Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
[36] {ECO:0000313|EMBL:KST32189.1}
NUCLEOTIDE SEQUENCE.
STRAIN=22593 {ECO:0000313|EMBL:KST32189.1};
Madec J.-Y., Haenni M.;
"Complete sequence of IncHI2 plasmid encoding blaCTX-M- and mcr-1.";
Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
[37] {ECO:0000313|Proteomes:UP000070045, ECO:0000313|Proteomes:UP000070338, ECO:0000313|Proteomes:UP000076106}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CFSAN025094 {ECO:0000313|EMBL:KXL60459.1,
ECO:0000313|Proteomes:UP000070338}, G28 {ECO:0000313|EMBL:KXR89032.1,
ECO:0000313|Proteomes:UP000070045},
STEC 1686 {ECO:0000313|EMBL:KYS97943.1,
ECO:0000313|Proteomes:UP000076106}, and
STEC 931 {ECO:0000313|EMBL:KYR52215.1,
ECO:0000313|Proteomes:UP000076262};
Shamseldin A., Moawad H., Abd El-Rahim W.M., Sadowsky M.J.;
Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
[38] {ECO:0000313|EMBL:ARR62155.1, ECO:0000313|Proteomes:UP000194311, ECO:0000313|Proteomes:UP000194331}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Strain Z247 {ECO:0000313|EMBL:ARR65179.1}, and
Z1002 {ECO:0000313|EMBL:ARR62155.1};
PubMed=27506685; DOI=.1093/cid/ciw553;
Zheng B., Dong H., Xu H., Lv J., Zhang J., Jiang X., Du Y., Xiao Y.,
Li L.;
"Coexistence of MCR-1 and NDM-1 in Clinical Escherichia coli
Isolates.";
Clin. Infect. Dis. 63:1393-1395(2016).
[39] {ECO:0000313|EMBL:OEI65690.1, ECO:0000313|Proteomes:UP000095183}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=EPEC 2827 {ECO:0000313|EMBL:OEI65690.1,
ECO:0000313|Proteomes:UP000095183};
Ferdous M., Kooistra-Smid A.M., Rossen J.W., Friedrich A.W.;
"Virulence, Antimicrobial resistance properties and Phylogenetic
background of E. coli O157 isolates that do not carry the H7 flagellar
antigen.";
Front. Microbiol. 0:0-0(2016).
[40] {ECO:0000313|EMBL:KST32189.1}
NUCLEOTIDE SEQUENCE.
STRAIN=22593 {ECO:0000313|EMBL:KST32189.1};
PubMed=26868385;
Valat C., Goldstone R.J., Hirchaud E., Haenni M., Smith D.G.,
Madec J.Y.;
"Draft Genome Sequences of Enterohemorrhagic Escherichia coli Encoding
Extended-Spectrum Beta-Lactamases.";
Genome Announc. 4:e01633-15(2016).
[41] {ECO:0000313|EMBL:KXH01378.1, ECO:0000313|Proteomes:UP000070450}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=JPH493 {ECO:0000313|EMBL:KXH01378.1,
ECO:0000313|Proteomes:UP000070450};
Wen L., He K., Yang H.;
Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
[42] {ECO:0000313|EMBL:AMW42571.1, ECO:0000313|Proteomes:UP000076266}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=28RC1 {ECO:0000313|EMBL:AMW42571.1,
ECO:0000313|Proteomes:UP000076266};
Baranzoni G.M., Fratamico P., Reichenberger E., Kim G.-H., Breidt F.,
Kay K.;
"Complete Genome Sequences of Escherichia coli O157:H7 strains SRCC
1675 and 28RC.";
Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
[43] {ECO:0000313|EMBL:ANK33519.1, ECO:0000313|Proteomes:UP000078545}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ECONIH2 {ECO:0000313|EMBL:ANK33519.1,
ECO:0000313|Proteomes:UP000078545};
Conlan S., Thomas P.J., Mullikin J., Palmore T.N., Frank K.M.,
Segre J.A.;
"Whole genome sequencing of Escherichia coli strain ECONIH2.";
Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
[44] {ECO:0000313|EMBL:ANO90585.1, ECO:0000313|Proteomes:UP000092566, ECO:0000313|Proteomes:UP000092652}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=06-00048 {ECO:0000313|EMBL:ANO90585.1,
ECO:0000313|Proteomes:UP000092566}, and
09-00049 {ECO:0000313|EMBL:ANP19578.1,
ECO:0000313|Proteomes:UP000092652};
Timme R., Allard M.W., Strain E., Evans P.S., Lorenz S., Brown E.;
"Whole genome shotgun sequencing of cultured foodborne pathogen.";
Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
[45] {ECO:0000313|EMBL:AOM71148.1, ECO:0000313|Proteomes:UP000094504}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=MS6198 {ECO:0000313|EMBL:AOM71148.1,
ECO:0000313|Proteomes:UP000094504};
Hancock S.J., Phan M.-D., Peters K.M., Forde B.M., Chan K.G.,
Beatson S.A., Schembri M.A.;
"Identification of Essential IncA/C Plasmid Genes and Development of a
Plasmid Multi-Locus Sequence-Type Scheme.";
Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
[46] {ECO:0000313|Proteomes:UP000196647, ECO:0000313|Proteomes:UP000196664, ECO:0000313|Proteomes:UP000196745}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ECOR39 {ECO:0000313|EMBL:OWE30460.1,
ECO:0000313|Proteomes:UP000196664},
ECOR47 {ECO:0000313|EMBL:OWD95226.1,
ECO:0000313|Proteomes:UP000196647},
ECOR62 {ECO:0000313|EMBL:OWC08691.1,
ECO:0000313|Proteomes:UP000198087},
ECOR65 {ECO:0000313|EMBL:OWE90906.1,
ECO:0000313|Proteomes:UP000196745}, and
ECOR70 {ECO:0000313|EMBL:OWF13778.1,
ECO:0000313|Proteomes:UP000196823};
Fischer W., Schubert S., Messerer M.;
"Investigation of Horizontal Gene Transfer of Pathogenicity Islands in
Escherichia coli using Next-Generation Sequencing.";
Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
[47] {ECO:0000313|EMBL:OWF28898.1, ECO:0000313|Proteomes:UP000196866}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ECOR51 {ECO:0000313|EMBL:OWF28898.1,
ECO:0000313|Proteomes:UP000196866};
Fischer W., Schubert S., Messerer M.;
"Investigation of Horizontal Gene Transfer of Pathogenicity Islands in
Escherichia coli using Next-Generation Sequencing.";
Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
[48] {ECO:0000313|EMBL:ONK53673.1, ECO:0000313|Proteomes:UP000188465}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=EC160090 {ECO:0000313|EMBL:ONK53673.1,
ECO:0000313|Proteomes:UP000188465};
Seilhamer J.J.;
Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
[49] {ECO:0000313|EMBL:OEN36434.1, ECO:0000313|Proteomes:UP000095493}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=VL119 {ECO:0000313|EMBL:OEN36434.1,
ECO:0000313|Proteomes:UP000095493};
Blum S.E., Goldstone R.J., Harris S., Leitner G., Smith D.G.;
"Genomic analysis of mastitis and farm-associated E. coli.";
Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
[50] {ECO:0000313|EMBL:APT01472.1, ECO:0000313|Proteomes:UP000185422}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=SLK172 {ECO:0000313|EMBL:APT01472.1,
ECO:0000313|Proteomes:UP000185422};
Bai L., Wang J., Hurley D., Yu Z., Wang L., Chen Q., Li J., Li F.,
Fanning S.;
"Characterisation of two large plasmids containing ESBL genes; a novel
disrupted mcr-1 gene and a lysogenized phage P-1 like sequence,
cultured from a human atypical enteropathogenic Escherichia coli
(aEPEC) recovered in China.";
Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
[51] {ECO:0000313|Proteomes:UP000184168, ECO:0000313|Proteomes:UP000184178, ECO:0000313|Proteomes:UP000184277}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=452 {ECO:0000313|EMBL:OJK74940.1,
ECO:0000313|Proteomes:UP000184168}, 559 {ECO:0000313|EMBL:OJP14027.1,
ECO:0000313|Proteomes:UP000184459}, 570 {ECO:0000313|EMBL:OJR54730.1,
ECO:0000313|Proteomes:UP000184277}, 634 {ECO:0000313|EMBL:OJM88468.1,
ECO:0000313|Proteomes:UP000184369}, 675 {ECO:0000313|EMBL:OJR16488.1,
ECO:0000313|Proteomes:UP000184355}, 708 {ECO:0000313|EMBL:OJR03376.1,
ECO:0000313|Proteomes:UP000184178}, and
726 {ECO:0000313|EMBL:OJS90484.1, ECO:0000313|Proteomes:UP000184336};
Wang Y., Zhang R., Li J., Wu Z., Wenjuan Y., Schwarz S., Tyrrell J.,
Zheng Y., Wang S., Shen Z., Liu Z., Lei L., Li M., Zhang Q., Wu C.,
Zhang Q., Wu Y., Walsh T., Shen J.;
"Comprehensive resistome analysis reveals the prevalence of NDM and
MCR-1 in Chinese poultry production.";
Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
[52] {ECO:0000313|EMBL:APA40841.1, ECO:0000313|Proteomes:UP000177471}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=PA20 {ECO:0000313|EMBL:APA40841.1,
ECO:0000313|Proteomes:UP000177471};
Uhlich G.A., Chen C.-Y., Paoli G.;
"E. coli O157:H7 PA20.";
Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
[53] {ECO:0000313|Proteomes:UP000188758, ECO:0000313|Proteomes:UP000188855, ECO:0000313|Proteomes:UP000189070}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=11.4-R4 {ECO:0000313|EMBL:OOJ23562.1,
ECO:0000313|Proteomes:UP000189070},
2.3-R4 {ECO:0000313|EMBL:OOK28426.1,
ECO:0000313|Proteomes:UP000188855}, and
4-R1 {ECO:0000313|EMBL:OOJ04544.1, ECO:0000313|Proteomes:UP000188758};
Moran R.A., Anantham S., Nigro S.J., Holt K.E., Hall R.M.;
"Whole genome sequences of antibiotic resistant commensal Escherichia
coli from healthy Australian adults.";
Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
[54] {ECO:0000313|EMBL:OKB79943.1, ECO:0000313|Proteomes:UP000185961, ECO:0000313|Proteomes:UP000186715}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=256 {ECO:0000313|EMBL:OKB91852.1,
ECO:0000313|Proteomes:UP000185961}, and
N11-1317 {ECO:0000313|EMBL:OKB79943.1,
ECO:0000313|Proteomes:UP000186715};
Tasara T., Fierz L., Klumpp J., Schmidt H., Stephan R.;
"Draft genome sequences of five Shigatoxin-producing Escherichia coli
isolates harboring the new recently described Subtilase cytotoxin
allelic variant subAB2-3.";
Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
[55] {ECO:0000313|EMBL:OLR88165.1, ECO:0000313|Proteomes:UP000186204}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=204965 {ECO:0000313|EMBL:OLR88165.1,
ECO:0000313|Proteomes:UP000186204};
Hartl R., Kerschner H., Lepuschitz S., Ruppitsch W., Allerberger F.,
Apfalter P.;
"First detection of the mcr-1 gene in a multidrug-resistant
Escherichia coli isolate from an Austrian patient.";
Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
[56] {ECO:0000313|EMBL:APT61250.1, ECO:0000313|Proteomes:UP000185501}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=2016C-3936C1 {ECO:0000313|EMBL:APT61250.1,
ECO:0000313|Proteomes:UP000185501};
Lindsey R.L., Batra D., Rowe L., Loparev V.N., Stripling D.,
Garcia-Toledo L., Knipe K., Juieng P., Sheth M., Martin H.,
Laufer Halpin A.;
"High Quality Genome Sequence of an Escherichia coli O157 carrying a
mcr-1 Resistance Gene Isolated from a Patient in the United States.";
Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
[57] {ECO:0000313|Proteomes:UP000189626, ECO:0000313|Proteomes:UP000189664, ECO:0000313|Proteomes:UP000189671}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Ecol_224 {ECO:0000313|EMBL:AQV19272.1,
ECO:0000313|Proteomes:UP000189671},
Ecol_316 {ECO:0000313|EMBL:AQV28759.1,
ECO:0000313|Proteomes:UP000189664}, and
Ecol_AZ146 {ECO:0000313|EMBL:AQV73106.1,
ECO:0000313|Proteomes:UP000189626};
Song W.-J., Kurnit D.M.;
Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
[58] {ECO:0000313|Proteomes:UP000185913, ECO:0000313|Proteomes:UP000186169, ECO:0000313|Proteomes:UP000186275}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=102928 {ECO:0000313|EMBL:OKW14748.1,
ECO:0000313|Proteomes:UP000185913},
602687 {ECO:0000313|EMBL:OKU14394.1,
ECO:0000313|Proteomes:UP000186169}, and
703098 {ECO:0000313|EMBL:OKU18502.1,
ECO:0000313|Proteomes:UP000186275};
Del Canto F., Vidal R., Stine O.C., Pop M.;
"Chaperone-usher pili loci of human colonization factor-negative
enterotoxigenic Escherichia coli.";
Front. Cell. Infect. Microbiol. 0:0-0(2017).
[59] {ECO:0000313|Proteomes:UP000214591, ECO:0000313|Proteomes:UP000214661, ECO:0000313|Proteomes:UP000214667}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=FC10225 {ECO:0000313|EMBL:OXK51756.1,
ECO:0000313|Proteomes:UP000214591},
FC10255 {ECO:0000313|EMBL:OXK10256.1,
ECO:0000313|Proteomes:UP000214667}, and
FC10274 {ECO:0000313|EMBL:OXJ81029.1,
ECO:0000313|Proteomes:UP000214661};
PubMed=28686503;
Luo Y., Luo R., Ding H., Ren X., Luo H., Zhang Y., Ye L., Cui S.;
"Characterization of Carbapenem-Resistant Escherichia coli Isolates
Through the Whole-Genome Sequencing Analysis.";
Microb. Drug Resist. 0:0-0(2017).
[60] {ECO:0000313|EMBL:ONG29123.1, ECO:0000313|Proteomes:UP000188967}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ICBEcBL-II-13 {ECO:0000313|EMBL:ONG29123.1,
ECO:0000313|Proteomes:UP000188967};
Moura Q., Fernandes M.R., Cerdeira L., Vianello M., Souza T.A.,
Ienne S., Lincopan N.;
"Draft genome sequence of an E. coli strain isolated from human, in
Amazon, Brazil.";
Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
[61] {ECO:0000313|EMBL:ONG31077.1, ECO:0000313|Proteomes:UP000188724}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ICBEC13AM {ECO:0000313|EMBL:ONG31077.1,
ECO:0000313|Proteomes:UP000188724};
Fernandes M.R., Sellera F.P., Esposito F., Cerdeira L., Lincopan N.;
"Draft genome sequence of Escherichia coli (ICBEC13AM) encoding mcr-1
gene in marine environment.";
Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
[62] {ECO:0000313|EMBL:OUK55296.1, ECO:0000313|Proteomes:UP000194908}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=SJRP/Ec42664 {ECO:0000313|EMBL:OUK55296.1};
Casella T., Cerdeira L., Lincopan N., Nogueira M.C.;
"Draft genome sequence of Escherichia coli strain SJRP/Ec42664.";
Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
[63] {ECO:0000313|EMBL:OUK51179.1, ECO:0000313|Proteomes:UP000195107}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=SJRP/Ec42687 {ECO:0000313|EMBL:OUK51179.1};
Casella T., Cerdeira L., Lincopan N., Nogueira M.C.;
"Draft genome sequence of Escherichia coli strain SJRP/Ec42687.";
Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
[64] {ECO:0000313|EMBL:OUL00379.1, ECO:0000313|Proteomes:UP000195177}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=SJRP/Ec42695 {ECO:0000313|EMBL:OUL00379.1};
Casella T., Cerdeira L., Lincopan N., Nogueira M.C.;
"Draft genome sequence of Escherichia coli strain SJRP/Ec42695.";
Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
[65] {ECO:0000313|EMBL:OOC83858.1, ECO:0000313|Proteomes:UP000188999}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=EDL 933 {ECO:0000313|EMBL:OOC83858.1,
ECO:0000313|Proteomes:UP000188999};
Kozyreva V.K., Truong C.-L., Greninger A.L., Mukhopadhyay R.,
Crandall J., Chaturvedi V.;
"Validation and Implementation of CLIA-Compliant Whole Genome
Sequencing (WGS) in Public Health Laboratory.";
Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
[66] {ECO:0000313|EMBL:OTB39597.1, ECO:0000313|Proteomes:UP000194247, ECO:0000313|Proteomes:UP000194319}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=OLC1000 {ECO:0000313|EMBL:OTB39597.1,
ECO:0000313|Proteomes:UP000194247}, and
OLC1257 {ECO:0000313|EMBL:OTE03079.1,
ECO:0000313|Proteomes:UP000194319};
Carrillo C.D., Koziol A.G., Mathews A., Goji N., Lambert D.,
Huszczynski G., Deschenes M., Gauthier M., Amoako K., Blais B.;
"Application of genomics in the determination of verotoxigenic
Escherichia coli toxin subtypes.";
Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
[67] {ECO:0000313|EMBL:OWS85717.1, ECO:0000313|Proteomes:UP000197917}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Ec39590 {ECO:0000313|EMBL:OWS85717.1,
ECO:0000313|Proteomes:UP000197917};
Melo L.C., Boisson M.N., Cerdeira L., Saras E., Medaille C.,
Boulois H.-J., Madec J.-Y., Haenni M., Lincopan N.;
"Draft Genome Sequence of Escherichia coli Isolated from Cat Harboring
blaTEM-52b.";
Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
[68] {ECO:0000313|EMBL:OTE91503.1, ECO:0000313|Proteomes:UP000194285}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=34VL {ECO:0000313|EMBL:OTE91503.1,
ECO:0000313|Proteomes:UP000194285};
Sartori L., Cerdeira L., Lincopan N.;
"Escherichia coli sequence carrying blaCTX-M-15 recovered from dairy
cow.";
Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
[69] {ECO:0000313|EMBL:ORD26430.1, ECO:0000313|Proteomes:UP000192295}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=OS_01_020_10 {ECO:0000313|EMBL:ORD26430.1,
ECO:0000313|Proteomes:UP000192295};
The Broad Institute Genomics Platform;
The Broad Institute Genomic Center for Infectious Diseases;
Earl A., Manson-Mcguire A., Hultgren S., Schreiber H., Chapman S.,
Conover M., Hibbing M., Stapleton A., Roberts P., Hooton T., Young S.,
Abouelleil A., Cao P., Cusick C., Shea T., Nusbaum C., Birren B.;
"The Genome Sequence of Escherichia coli OS_01_020_10.";
Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
[70] {ECO:0000313|Proteomes:UP000193168, ECO:0000313|Proteomes:UP000193530, ECO:0000313|Proteomes:UP000197281}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=KCJK1770 {ECO:0000313|EMBL:OWX81492.1,
ECO:0000313|Proteomes:UP000197281},
KCJK1866 {ECO:0000313|EMBL:ORJ75828.1,
ECO:0000313|Proteomes:UP000193168},
KCJK1886 {ECO:0000313|EMBL:OWX90458.1,
ECO:0000313|Proteomes:UP000197700}, and
KCJK2140 {ECO:0000313|EMBL:ORT01698.1,
ECO:0000313|Proteomes:UP000193530};
Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
Dimitrov K.M., Suarez D.L., Swayne D.E.;
Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
[71] {ECO:0000313|EMBL:ARR33953.1, ECO:0000313|Proteomes:UP000194199}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=5CRE51 {ECO:0000313|EMBL:ARR33953.1,
ECO:0000313|Proteomes:UP000194199};
Mu J.-J., Lin Y.-C.;
"Coexistence of MCR-1 and NDM-9 in Escherichia coli clinical isolate
in Taiwan.";
Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
[72] {ECO:0000313|EMBL:ASA41638.1, ECO:0000313|Proteomes:UP000196470}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=H105 {ECO:0000313|EMBL:ASA41638.1,
ECO:0000313|Proteomes:UP000196470};
Ghosh H., Doijad S., Chakraborty T.;
"Complete Genome Sequence of a CTX-M-27 encoding C1/H30R/C1-M27
Escherichia coli ST131 H105.";
Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
[73] {ECO:0000313|EMBL:OWY56979.1, ECO:0000313|Proteomes:UP000197325}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=30934 {ECO:0000313|EMBL:OWY56979.1,
ECO:0000313|Proteomes:UP000197325};
Valat C.;
"Effects of subinhibitory concentration of ciprofloxacin on resistance
and virulence of Escherichia coli.";
Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
[74] {ECO:0000313|EMBL:OUG25243.1, ECO:0000313|Proteomes:UP000194954}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=UCI121 {ECO:0000313|EMBL:OUG25243.1};
The Broad Institute Genomics Platform;
The Broad Institute Genomic Center for Infectious Diseases;
Earl A., Cerqueira G., Kirby J., Ferraro M., Onderdonk A., Delaney M.,
Kim D., Gussin G., Young S., Abouelleil A., Cao P., Chapman S.,
Cusick C., Shea T., Neafsey D., Nusbaum C., Birren B.;
"The Genome Sequence of Escherichia coli UCI121.";
Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
[75] {ECO:0000313|EMBL:ARR62155.1}
NUCLEOTIDE SEQUENCE.
STRAIN=Strain Z247 {ECO:0000313|EMBL:ARR65179.1}, and
Z1002 {ECO:0000313|EMBL:ARR62155.1};
Song R., Chenine A.L., Ruprecht R.M.;
Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
[76] {ECO:0000313|EMBL:OXV13648.1, ECO:0000313|Proteomes:UP000214921}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ICBEcBL-II-11 {ECO:0000313|EMBL:OXV13648.1}, and
ICBEcBL-II-11(1) {ECO:0000313|Proteomes:UP000214921};
Moura Q., Fernandes M.R., Cerdeira L., Vianello M., Souza T.A.,
Ienne S., Lincopan N.;
"Draft genome of a CTX-M-15-producing Escherichia coli, ST 648,
isolated from human, in Amazon, Brazil.";
Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
[77] {ECO:0000313|EMBL:ASG48521.1, ECO:0000313|Proteomes:UP000197584}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ABWA45 {ECO:0000313|EMBL:ASG48521.1,
ECO:0000313|Proteomes:UP000197584};
Zurfluh K., Stephan R., Klumpp J., Hummerjohann J., Bagutti C.,
Marti R.;
"Genome of Escherichia coli isolate ABWA45, an rmtB encoding
wastewater isolate.";
Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
[78] {ECO:0000313|EMBL:ARX55331.1, ECO:0000313|Proteomes:UP000196389}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=AR_0128 {ECO:0000313|EMBL:ARX55331.1,
ECO:0000313|Proteomes:UP000196389};
Conlan S., Thomas P.J., Mullikin J., Frank K.M., Segre J.A.;
"Whole genome sequencing of Escherichia coli AR_0128.";
Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
[79] {ECO:0000313|EMBL:OYK37181.1, ECO:0000313|Proteomes:UP000215519}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ECPUTH02 {ECO:0000313|EMBL:OYK37181.1,
ECO:0000313|Proteomes:UP000215519};
de Groot N.N.;
Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
-!- FUNCTION: Catalyzes the ATP-dependent amination of UTP to CTP with
either L-glutamine or ammonia as the source of nitrogen. Regulates
intracellular CTP levels through interactions with the four
ribonucleotide triphosphates. {ECO:0000256|HAMAP-Rule:MF_01227}.
-!- CATALYTIC ACTIVITY: ATP + UTP + L-glutamine = ADP + phosphate +
CTP + L-glutamate. {ECO:0000256|HAMAP-Rule:MF_01227,
ECO:0000256|SAAS:SAAS00710710}.
-!- ENZYME REGULATION: Allosterically activated by GTP, when glutamine
is the substrate; GTP has no effect on the reaction when ammonia
is the substrate. The allosteric effector GTP functions by
stabilizing the protein conformation that binds the tetrahedral
intermediate(s) formed during glutamine hydrolysis. Inhibited by
the product CTP, via allosteric rather than competitive
inhibition. {ECO:0000256|HAMAP-Rule:MF_01227}.
-!- PATHWAY: Pyrimidine metabolism; CTP biosynthesis via de novo
pathway; CTP from UDP: step 2/2. {ECO:0000256|HAMAP-Rule:MF_01227,
ECO:0000256|SAAS:SAAS00710815}.
-!- SUBUNIT: Homotetramer. {ECO:0000256|HAMAP-Rule:MF_01227,
ECO:0000256|SAAS:SAAS00710816}.
-!- MISCELLANEOUS: CTPSs have evolved a hybrid strategy for
distinguishing between UTP and CTP. The overlapping regions of the
product feedback inhibitory and substrate sites recognize a common
feature in both compounds, the triphosphate moiety. To
differentiate isosteric substrate and product pyrimidine rings, an
additional pocket far from the expected kinase/ligase catalytic
site, specifically recognizes the cytosine and ribose portions of
the product inhibitor. {ECO:0000256|HAMAP-Rule:MF_01227}.
-!- SIMILARITY: Belongs to the CTP synthase family.
{ECO:0000256|HAMAP-Rule:MF_01227, ECO:0000256|SAAS:SAAS00710794}.
-!- CAUTION: Lacks conserved residue(s) required for the propagation
of feature annotation. {ECO:0000256|HAMAP-Rule:MF_01227}.
-----------------------------------------------------------------------
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EMBL; EU896500; ACI79056.1; -; Genomic_DNA.
EMBL; EU896501; ACI79057.1; -; Genomic_DNA.
EMBL; EU896502; ACI79058.1; -; Genomic_DNA.
EMBL; EU896504; ACI79060.1; -; Genomic_DNA.
EMBL; CP009859; AIX64615.1; -; Genomic_DNA.
EMBL; CP009104; AIZ83819.1; -; Genomic_DNA.
EMBL; CP010315; AJE57317.1; -; Genomic_DNA.
EMBL; CP010876; AJO84759.1; -; Genomic_DNA.
EMBL; CP011416; AKH23448.1; -; Genomic_DNA.
EMBL; CP013025; ALL89202.1; -; Genomic_DNA.
EMBL; CP007491; ALY14255.1; -; Genomic_DNA.
EMBL; CP015020; AMW42571.1; -; Genomic_DNA.
EMBL; CP014667; ANK33519.1; -; Genomic_DNA.
EMBL; CP015229; ANO90585.1; -; Genomic_DNA.
EMBL; CP015228; ANP19578.1; -; Genomic_DNA.
EMBL; CP012693; AOM44101.1; -; Genomic_DNA.
EMBL; CP015834; AOM71148.1; -; Genomic_DNA.
EMBL; CP017669; APA40841.1; -; Genomic_DNA.
EMBL; CP010122; APJ76174.1; -; Genomic_DNA.
EMBL; CP017631; APT01472.1; -; Genomic_DNA.
EMBL; CP018770; APT61250.1; -; Genomic_DNA.
EMBL; CP018948; AQV19272.1; -; Genomic_DNA.
EMBL; CP018957; AQV28759.1; -; Genomic_DNA.
EMBL; CP018991; AQV73106.1; -; Genomic_DNA.
EMBL; CP021175; ARR33953.1; -; Genomic_DNA.
EMBL; CP021202; ARR62155.1; -; Genomic_DNA.
EMBL; CP021207; ARR65179.1; -; Genomic_DNA.
EMBL; CP021722; ARX55331.1; -; Genomic_DNA.
EMBL; CP021454; ASA41638.1; -; Genomic_DNA.
EMBL; CP022154; ASG48521.1; -; Genomic_DNA.
EMBL; CP012378; ASO77854.1; -; Genomic_DNA.
EMBL; HE964769; CCJ45363.1; -; Genomic_DNA.
EMBL; HG976963; CDU41322.1; -; Genomic_DNA.
EMBL; CXZU01000021; CTS03443.1; -; Genomic_DNA.
EMBL; CYAQ01000019; CTS74713.1; -; Genomic_DNA.
EMBL; CYAV01000035; CTT27611.1; -; Genomic_DNA.
EMBL; CYBM01000018; CTU02464.1; -; Genomic_DNA.
EMBL; CYDH01000018; CTV91638.1; -; Genomic_DNA.
EMBL; CYCX01000022; CTW24677.1; -; Genomic_DNA.
EMBL; CYFX01000010; CTZ37548.1; -; Genomic_DNA.
EMBL; CYGC01000007; CTZ62786.1; -; Genomic_DNA.
EMBL; JPQG01000003; KFD75255.1; -; Genomic_DNA.
EMBL; JPKH01000006; KGM71258.1; -; Genomic_DNA.
EMBL; JPKL01000016; KGM83222.1; -; Genomic_DNA.
EMBL; JPMZ01000005; KGM84781.1; -; Genomic_DNA.
EMBL; JUDN01000004; KHJ23402.1; -; Genomic_DNA.
EMBL; JYEF01000094; KJH05916.1; -; Genomic_DNA.
EMBL; JZDZ01000048; KJW53122.1; -; Genomic_DNA.
EMBL; LEUM01000018; KLX95482.1; -; Genomic_DNA.
EMBL; LEYN01000023; KME68389.1; -; Genomic_DNA.
EMBL; LGZN01000018; KNF70809.1; -; Genomic_DNA.
EMBL; LGZP01000017; KNF80526.1; -; Genomic_DNA.
EMBL; LHAT01000009; KOA00539.1; -; Genomic_DNA.
EMBL; LFZI01000030; KOA27540.1; -; Genomic_DNA.
EMBL; LDYI01000161; KPO04853.1; -; Genomic_DNA.
EMBL; LECN01000160; KPO46814.1; -; Genomic_DNA.
EMBL; LIVE01000042; KQJ12937.1; -; Genomic_DNA.
EMBL; LIVI01000001; KQJ46203.1; -; Genomic_DNA.
EMBL; LMBK01000235; KST32189.1; -; Genomic_DNA.
EMBL; LNHR01000017; KSY01530.1; -; Genomic_DNA.
EMBL; LNIP01000040; KSZ14044.1; -; Genomic_DNA.
EMBL; LSNZ01000048; KXH01378.1; -; Genomic_DNA.
EMBL; LPXZ01000187; KXL60459.1; -; Genomic_DNA.
EMBL; LOOZ01000024; KXR89032.1; -; Genomic_DNA.
EMBL; LOFS01000143; KYR52215.1; -; Genomic_DNA.
EMBL; LOGT01000057; KYS97943.1; -; Genomic_DNA.
EMBL; LCVH01000048; OAC43282.1; -; Genomic_DNA.
EMBL; LZEH01000101; OEI65690.1; -; Genomic_DNA.
EMBL; MIWY01000005; OEN36434.1; -; Genomic_DNA.
EMBL; MOFD01000023; OJK74940.1; -; Genomic_DNA.
EMBL; MOGU01000039; OJM88468.1; -; Genomic_DNA.
EMBL; MOIL01000010; OJP14027.1; -; Genomic_DNA.
EMBL; MOJX01000028; OJR03376.1; -; Genomic_DNA.
EMBL; MOKA01000015; OJR16488.1; -; Genomic_DNA.
EMBL; MOKI01000024; OJR54730.1; -; Genomic_DNA.
EMBL; MOKZ01000005; OJS90484.1; -; Genomic_DNA.
EMBL; MPGQ01000001; OKB79943.1; -; Genomic_DNA.
EMBL; MPGT01000001; OKB91852.1; -; Genomic_DNA.
EMBL; LGMU01000100; OKU14394.1; -; Genomic_DNA.
EMBL; LGMY01000210; OKU18502.1; -; Genomic_DNA.
EMBL; LRLE01000077; OKW14748.1; -; Genomic_DNA.
EMBL; MSEK01000046; OLR88165.1; -; Genomic_DNA.
EMBL; MTPS01000486; ONG29123.1; -; Genomic_DNA.
EMBL; MTKH01000027; ONG31077.1; -; Genomic_DNA.
EMBL; MCNL01000631; ONK53673.1; -; Genomic_DNA.
EMBL; MTFS01000004; OOC83858.1; -; Genomic_DNA.
EMBL; MOZG01000029; OOJ04544.1; -; Genomic_DNA.
EMBL; MOZJ01000003; OOJ23562.1; -; Genomic_DNA.
EMBL; MPAF01000017; OOK28426.1; -; Genomic_DNA.
EMBL; NCRV01000002; ORD26430.1; -; Genomic_DNA.
EMBL; NAHY01000256; ORJ75828.1; -; Genomic_DNA.
EMBL; NAFT01000058; ORT01698.1; -; Genomic_DNA.
EMBL; NEME01000005; OTB39597.1; -; Genomic_DNA.
EMBL; NENZ01000001; OTE03079.1; -; Genomic_DNA.
EMBL; NBCM01000023; OTE91503.1; -; Genomic_DNA.
EMBL; NGSK01000005; OUG25243.1; -; Genomic_DNA.
EMBL; MUAC01000029; OUK51179.1; -; Genomic_DNA.
EMBL; MUAB01000001; OUK55296.1; -; Genomic_DNA.
EMBL; MUBQ01000002; OUL00379.1; -; Genomic_DNA.
EMBL; LYDL01000110; OWC08691.1; -; Genomic_DNA.
EMBL; LYCB01000835; OWD95226.1; -; Genomic_DNA.
EMBL; LYCJ01000720; OWE30460.1; -; Genomic_DNA.
EMBL; LYDD01000112; OWE90906.1; -; Genomic_DNA.
EMBL; LYDH01000291; OWF13778.1; -; Genomic_DNA.
EMBL; LYYB01001662; OWF28898.1; -; Genomic_DNA.
EMBL; NBSF01000015; OWS85717.1; -; Genomic_DNA.
EMBL; NACG01000048; OWX81492.1; -; Genomic_DNA.
EMBL; NACI01000031; OWX90458.1; -; Genomic_DNA.
EMBL; NIPT01000004; OWY56979.1; -; Genomic_DNA.
EMBL; NIIE01000013; OXJ81029.1; -; Genomic_DNA.
EMBL; NIIK01000022; OXK10256.1; -; Genomic_DNA.
EMBL; NIIS01000046; OXK51756.1; -; Genomic_DNA.
EMBL; NIHH01000054; OXV13648.1; -; Genomic_DNA.
EMBL; NQDM01000090; OYK37181.1; -; Genomic_DNA.
RefSeq; WP_000210878.1; NZ_NQJC01000043.1.
STRING; 469008.ECD_02625; -.
EnsemblBacteria; AIX64615; AIX64615; ECONIH1_15890.
EnsemblBacteria; AIZ83819; AIZ83819; HW42_18535.
EnsemblBacteria; AJE57317; AJE57317; AC789_1c31020.
EnsemblBacteria; AJO84759; AJO84759; SY51_15605.
EnsemblBacteria; AKH23448; AKH23448; AA102_05735.
EnsemblBacteria; ALD23917; ALD23917; AN206_05525.
EnsemblBacteria; ALL89202; ALL89202; MJ49_17095.
EnsemblBacteria; ALY14255; ALY14255; ACN002_2797.
EnsemblBacteria; ALZ66002; ALZ66002; AWH59_07475.
EnsemblBacteria; AMW42571; AMW42571; ARC77_10140.
EnsemblBacteria; AMX14650; AMX14650; A4X18_14675.
EnsemblBacteria; ANK33519; ANK33519; WM48_14990.
EnsemblBacteria; ANM83519; ANM83519; A8V37_13845.
EnsemblBacteria; ANO90585; ANO90585; GJ11_18025.
EnsemblBacteria; ANP19578; ANP19578; GJ12_17995.
EnsemblBacteria; AOM44101; AOM44101; FORC28_1110.
EnsemblBacteria; AOM71148; AOM71148; MS6198_30910.
EnsemblBacteria; AOT31548; AOT31548; FORC31_1083.
EnsemblBacteria; CDU41322; CDU41322; PGD_04325.
EnsemblBacteria; CRL91106; CRL91106; AL505_50220.
EnsemblBacteria; CTS03443; CTS03443; ERS085374_03279.
EnsemblBacteria; CTS74713; CTS74713; ERS085365_02427.
EnsemblBacteria; CTT27611; CTT27611; ERS085366_03042.
EnsemblBacteria; CTU02464; CTU02464; ERS085386_03410.
EnsemblBacteria; CTV91638; CTV91638; ERS139211_02072.
EnsemblBacteria; CTW24677; CTW24677; ERS085416_02898.
EnsemblBacteria; CTW94608; CTW94608; ERS139235_00258.
EnsemblBacteria; CTX92768; CTX92768; ERS139266_01670.
EnsemblBacteria; CTY00438; CTY00438; ERS139269_00604.
EnsemblBacteria; CTZ37548; CTZ37548; ERS150873_02003.
EnsemblBacteria; CTZ62786; CTZ62786; ERS150876_01467.
EnsemblBacteria; KFD75255; KFD75255; JD73_16335.
EnsemblBacteria; KGM71258; KGM71258; EL75_0914.
EnsemblBacteria; KGM83222; KGM83222; EL80_0918.
EnsemblBacteria; KGM84781; KGM84781; EL79_0915.
EnsemblBacteria; KHH09275; KHH09275; PU69_10605.
EnsemblBacteria; KHI37510; KHI37510; PU33_02575.
EnsemblBacteria; KHJ23402; KHJ23402; PU06_02080.
EnsemblBacteria; KIG80436; KIG80436; PU38_14495.
EnsemblBacteria; KIH07113; KIH07113; PU21_03905.
EnsemblBacteria; KIH34812; KIH34812; PD07_17575.
EnsemblBacteria; KIQ46181; KIQ46181; IY32_12395.
EnsemblBacteria; KJH05916; KJH05916; UC41_20365.
EnsemblBacteria; KJW53122; KJW53122; UN91_03645.
EnsemblBacteria; KLG77861; KLG77861; WR12_09715.
EnsemblBacteria; KLX57673; KLX57673; SK78_01922.
EnsemblBacteria; KLX93088; KLX93088; SK83_00163.
EnsemblBacteria; KLX95482; KLX95482; SK85_03024.
EnsemblBacteria; KME68389; KME68389; SM09_02917.
EnsemblBacteria; KNF70809; KNF70809; WR15_06090.
EnsemblBacteria; KNF80526; KNF80526; WQ89_10170.
EnsemblBacteria; KNY78268; KNY78268; AGA26_01480.
EnsemblBacteria; KOA00539; KOA00539; AKG99_03555.
EnsemblBacteria; KOA27540; KOA27540; AC067_22330.
EnsemblBacteria; KPO04853; KPO04853; ACU57_24415.
EnsemblBacteria; KPO37621; KPO37621; ACU81_14990.
EnsemblBacteria; KPO46814; KPO46814; ACU90_23015.
EnsemblBacteria; KQJ12937; KQJ12937; AM266_20155.
EnsemblBacteria; KQJ46203; KQJ46203; AM270_00945.
EnsemblBacteria; KST32189; KST32189; APZ14_09290.
EnsemblBacteria; KSY01530; KSY01530; APT94_17890.
EnsemblBacteria; KSZ14044; KSZ14044; APU18_18535.
EnsemblBacteria; KUU48313; KUU48313; AWF22_26270.
EnsemblBacteria; KXG92712; KXG92712; HMPREF3041_03524.
EnsemblBacteria; KXH01378; KXH01378; HMPREF3040_01161.
EnsemblBacteria; KXH98879; KXH98879; AXE68_20220.
EnsemblBacteria; KXL60459; KXL60459; AUS26_15660.
EnsemblBacteria; KXQ40741; KXQ40741; AUQ01_08185.
EnsemblBacteria; KYR52215; KYR52215; AML07_12460.
EnsemblBacteria; KYS97943; KYS97943; AML35_05300.
EnsemblBacteria; KZJ53157; KZJ53157; AWG90_18365.
EnsemblBacteria; OAC43282; OAC43282; EC3234A_48c00890.
EnsemblBacteria; OAF45132; OAF45132; AXK33_08705.
EnsemblBacteria; OAO69582; OAO69582; OO96_08870.
EnsemblBacteria; OAO74011; OAO74011; OK10_10175.
EnsemblBacteria; OAS94201; OAS94201; A6I92_15775.
EnsemblBacteria; OCO50670; OCO50670; AN669_0216350.
EnsemblBacteria; OCS77379; OCS77379; BBZ52_14835.
EnsemblBacteria; ODA88661; ODA88661; A9D65_02045.
EnsemblBacteria; ODH24636; ODH24636; A6804_05520.
EnsemblBacteria; ODH32155; ODH32155; A6803_04650.
EnsemblBacteria; OEG65989; OEG65989; A7H95_12000.
EnsemblBacteria; OEI65690; OEI65690; A9R57_06965.
EnsemblBacteria; OEN36434; OEN36434; BHF46_05050.
PATRIC; fig|562.10471.peg.3123; -.
eggNOG; ENOG4105C8D; Bacteria.
eggNOG; COG0504; LUCA.
HOGENOM; HOG000077515; -.
UniPathway; UPA00159; UER00277.
Proteomes; UP000028651; Unassembled WGS sequence.
Proteomes; UP000029988; Unassembled WGS sequence.
Proteomes; UP000030000; Unassembled WGS sequence.
Proteomes; UP000030018; Unassembled WGS sequence.
Proteomes; UP000030317; Chromosome.
Proteomes; UP000030790; Chromosome.
Proteomes; UP000030834; Unassembled WGS sequence.
Proteomes; UP000031522; Chromosome.
Proteomes; UP000032290; Chromosome.
Proteomes; UP000032456; Unassembled WGS sequence.
Proteomes; UP000033371; Unassembled WGS sequence.
Proteomes; UP000034530; Chromosome.
Proteomes; UP000036012; Unassembled WGS sequence.
Proteomes; UP000036405; Unassembled WGS sequence.
Proteomes; UP000036728; Unassembled WGS sequence.
Proteomes; UP000036812; Unassembled WGS sequence.
Proteomes; UP000037153; Unassembled WGS sequence.
Proteomes; UP000037564; Unassembled WGS sequence.
Proteomes; UP000038112; Unassembled WGS sequence.
Proteomes; UP000040934; Unassembled WGS sequence.
Proteomes; UP000041959; Unassembled WGS sequence.
Proteomes; UP000042305; Unassembled WGS sequence.
Proteomes; UP000042887; Unassembled WGS sequence.
Proteomes; UP000044469; Unassembled WGS sequence.
Proteomes; UP000044893; Unassembled WGS sequence.
Proteomes; UP000045242; Unassembled WGS sequence.
Proteomes; UP000050307; Unassembled WGS sequence.
Proteomes; UP000050556; Unassembled WGS sequence.
Proteomes; UP000051846; Unassembled WGS sequence.
Proteomes; UP000051850; Unassembled WGS sequence.
Proteomes; UP000053450; Unassembled WGS sequence.
Proteomes; UP000054277; Unassembled WGS sequence.
Proteomes; UP000054864; Unassembled WGS sequence.
Proteomes; UP000065978; Chromosome.
Proteomes; UP000066343; Chromosome.
Proteomes; UP000070045; Unassembled WGS sequence.
Proteomes; UP000070338; Unassembled WGS sequence.
Proteomes; UP000070450; Unassembled WGS sequence.
Proteomes; UP000076106; Unassembled WGS sequence.
Proteomes; UP000076262; Unassembled WGS sequence.
Proteomes; UP000076266; Chromosome.
Proteomes; UP000077380; Unassembled WGS sequence.
Proteomes; UP000078545; Chromosome.
Proteomes; UP000092566; Chromosome.
Proteomes; UP000092652; Chromosome.
Proteomes; UP000094022; Unassembled WGS sequence.
Proteomes; UP000094451; Chromosome.
Proteomes; UP000094504; Chromosome.
Proteomes; UP000095183; Unassembled WGS sequence.
Proteomes; UP000095493; Unassembled WGS sequence.
Proteomes; UP000177471; Chromosome.
Proteomes; UP000184168; Unassembled WGS sequence.
Proteomes; UP000184178; Unassembled WGS sequence.
Proteomes; UP000184277; Unassembled WGS sequence.
Proteomes; UP000184336; Unassembled WGS sequence.
Proteomes; UP000184355; Unassembled WGS sequence.
Proteomes; UP000184369; Unassembled WGS sequence.
Proteomes; UP000184379; Chromosome.
Proteomes; UP000184459; Unassembled WGS sequence.
Proteomes; UP000185422; Chromosome.
Proteomes; UP000185501; Chromosome.
Proteomes; UP000185913; Unassembled WGS sequence.
Proteomes; UP000185961; Unassembled WGS sequence.
Proteomes; UP000186169; Unassembled WGS sequence.
Proteomes; UP000186204; Unassembled WGS sequence.
Proteomes; UP000186275; Unassembled WGS sequence.
Proteomes; UP000186715; Unassembled WGS sequence.
Proteomes; UP000188465; Unassembled WGS sequence.
Proteomes; UP000188724; Unassembled WGS sequence.
Proteomes; UP000188758; Unassembled WGS sequence.
Proteomes; UP000188855; Unassembled WGS sequence.
Proteomes; UP000188967; Unassembled WGS sequence.
Proteomes; UP000188999; Unassembled WGS sequence.
Proteomes; UP000189070; Unassembled WGS sequence.
Proteomes; UP000189626; Chromosome.
Proteomes; UP000189664; Chromosome.
Proteomes; UP000189671; Chromosome.
Proteomes; UP000192295; Unassembled WGS sequence.
Proteomes; UP000193168; Unassembled WGS sequence.
Proteomes; UP000193530; Unassembled WGS sequence.
Proteomes; UP000194199; Chromosome.
Proteomes; UP000194247; Unassembled WGS sequence.
Proteomes; UP000194285; Unassembled WGS sequence.
Proteomes; UP000194311; Chromosome.
Proteomes; UP000194319; Unassembled WGS sequence.
Proteomes; UP000194331; Chromosome.
Proteomes; UP000194908; Unassembled WGS sequence.
Proteomes; UP000194954; Unassembled WGS sequence.
Proteomes; UP000195107; Unassembled WGS sequence.
Proteomes; UP000195177; Unassembled WGS sequence.
Proteomes; UP000196389; Chromosome.
Proteomes; UP000196470; Chromosome.
Proteomes; UP000196647; Unassembled WGS sequence.
Proteomes; UP000196664; Unassembled WGS sequence.
Proteomes; UP000196745; Unassembled WGS sequence.
Proteomes; UP000196823; Unassembled WGS sequence.
Proteomes; UP000196866; Unassembled WGS sequence.
Proteomes; UP000197281; Unassembled WGS sequence.
Proteomes; UP000197325; Unassembled WGS sequence.
Proteomes; UP000197584; Chromosome.
Proteomes; UP000197700; Unassembled WGS sequence.
Proteomes; UP000197917; Unassembled WGS sequence.
Proteomes; UP000198087; Unassembled WGS sequence.
Proteomes; UP000203621; Chromosome.
Proteomes; UP000214591; Unassembled WGS sequence.
Proteomes; UP000214661; Unassembled WGS sequence.
Proteomes; UP000214667; Unassembled WGS sequence.
Proteomes; UP000214921; Unassembled WGS sequence.
Proteomes; UP000215519; Unassembled WGS sequence.
GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO; GO:0003883; F:CTP synthase activity; IEA:UniProtKB-UniRule.
GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO; GO:0044210; P:'de novo' CTP biosynthetic process; IEA:UniProtKB-UniPathway.
GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
CDD; cd01746; GATase1_CTP_Synthase; 1.
Gene3D; 3.40.50.880; -; 1.
HAMAP; MF_01227; PyrG; 1.
InterPro; IPR029062; Class_I_gatase-like.
InterPro; IPR004468; CTP_synthase.
InterPro; IPR017456; CTP_synthase_N.
InterPro; IPR017926; GATASE.
InterPro; IPR033828; GATase1_CTP_Synthase.
InterPro; IPR027417; P-loop_NTPase.
PANTHER; PTHR11550; PTHR11550; 1.
Pfam; PF06418; CTP_synth_N; 1.
Pfam; PF00117; GATase; 1.
SUPFAM; SSF52317; SSF52317; 1.
SUPFAM; SSF52540; SSF52540; 1.
TIGRFAMs; TIGR00337; PyrG; 1.
PROSITE; PS51273; GATASE_TYPE_1; 1.
3: Inferred from homology;
ATP-binding {ECO:0000256|HAMAP-Rule:MF_01227,
ECO:0000256|SAAS:SAAS00710699};
Complete proteome {ECO:0000313|Proteomes:UP000028651,
ECO:0000313|Proteomes:UP000029988, ECO:0000313|Proteomes:UP000030000,
ECO:0000313|Proteomes:UP000030018};
Glutamine amidotransferase {ECO:0000256|HAMAP-Rule:MF_01227,
ECO:0000256|SAAS:SAAS00710676};
Ligase {ECO:0000256|HAMAP-Rule:MF_01227,
ECO:0000256|SAAS:SAAS00710762, ECO:0000313|EMBL:AIX64615.1};
Magnesium {ECO:0000256|HAMAP-Rule:MF_01227,
ECO:0000256|SAAS:SAAS00710689};
Metal-binding {ECO:0000256|HAMAP-Rule:MF_01227,
ECO:0000256|SAAS:SAAS00710675};
Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01227,
ECO:0000256|SAAS:SAAS00710699};
Pyrimidine biosynthesis {ECO:0000256|HAMAP-Rule:MF_01227,
ECO:0000256|SAAS:SAAS00710748}.
DOMAIN 291 542 Glutamine amidotransferase type-1.
{ECO:0000259|PROSITE:PS51273}.
NP_BIND 15 20 ATP. {ECO:0000256|HAMAP-Rule:MF_01227}.
NP_BIND 147 149 Allosteric inhibitor CTP.
{ECO:0000256|HAMAP-Rule:MF_01227}.
NP_BIND 187 192 Allosteric inhibitor CTP; alternate.
{ECO:0000256|HAMAP-Rule:MF_01227}.
NP_BIND 187 192 UTP; alternate. {ECO:0000256|HAMAP-
Rule:MF_01227}.
NP_BIND 239 241 ATP; via amide nitrogen.
{ECO:0000256|HAMAP-Rule:MF_01227}.
REGION 1 266 Amidoligase domain. {ECO:0000256|HAMAP-
Rule:MF_01227}.
REGION 380 383 L-glutamine binding. {ECO:0000256|HAMAP-
Rule:MF_01227}.
ACT_SITE 379 379 Nucleophile; for glutamine hydrolysis.
{ECO:0000256|HAMAP-Rule:MF_01227}.
ACT_SITE 515 515 {ECO:0000256|HAMAP-Rule:MF_01227}.
ACT_SITE 517 517 {ECO:0000256|HAMAP-Rule:MF_01227}.
METAL 72 72 Magnesium. {ECO:0000256|HAMAP-
Rule:MF_01227}.
METAL 140 140 Magnesium. {ECO:0000256|HAMAP-
Rule:MF_01227}.
BINDING 14 14 Allosteric inhibitor CTP; alternate.
{ECO:0000256|HAMAP-Rule:MF_01227}.
BINDING 14 14 UTP; alternate. {ECO:0000256|HAMAP-
Rule:MF_01227}.
BINDING 72 72 ATP. {ECO:0000256|HAMAP-Rule:MF_01227}.
BINDING 223 223 Allosteric inhibitor CTP; alternate.
{ECO:0000256|HAMAP-Rule:MF_01227}.
BINDING 223 223 UTP; alternate. {ECO:0000256|HAMAP-
Rule:MF_01227}.
BINDING 352 352 L-glutamine; via carbonyl oxygen.
{ECO:0000256|HAMAP-Rule:MF_01227}.
BINDING 403 403 L-glutamine. {ECO:0000256|HAMAP-
Rule:MF_01227}.
BINDING 470 470 L-glutamine; via amide nitrogen.
{ECO:0000256|HAMAP-Rule:MF_01227}.
SEQUENCE 545 AA; 60374 MW; FBB9E2E18FA355FC CRC64;
MTTNYIFVTG GVVSSLGKGI AAASLAAILE ARGLNVTIMK LDPYINVDPG TMSPIQHGEV
FVTEDGAETD LDLGHYERFI RTKMSRRNNF TTGRIYSDVL RKERRGDYLG ATVQVIPHIT
NAIKERVLEG GEGHDVVLVE IGGTVGDIES LPFLEAIRQM AVEIGREHTL FMHLTLVPYM
AASGEVKTKP TQHSVKELLS IGIQPDILIC RSDRAVPANE RAKIALFCNV PEKAVISLKD
VDSIYKIPGL LKSQGLDDYI CKRFSLNCPE ANLSEWEQVI FEEANPVSEV TIGMVGKYIE
LPDAYKSVIE ALKHGGLKNR VSVNIKLIDS QDVETRGVEI LKGLDAILVP GGFGYRGVEG
MITTARFARE NNIPYLGICL GMQVALIDYA RHVANMENAN STEFVPDCKY PVVALITEWR
DENGNVEVRS EKSDLGGTMR LGAQQCQLVD DSLVRQLYNA PTIVERHRHR YEVNNMLLKQ
IEDAGLRVAG RSGDDQLVEI IEVPNHPWFV ACQFHPEFTS TPRDGHPLFA GFVKAASEFQ
KRQAK


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