Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

CX3C chemokine receptor 1 (C-X3-C CKR-1) (CX3CR1) (Fractalkine receptor)

 CX3C1_BOVIN             Reviewed;         358 AA.
A6QNL7;
26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
21-AUG-2007, sequence version 1.
28-MAR-2018, entry version 74.
RecName: Full=CX3C chemokine receptor 1;
Short=C-X3-C CKR-1;
Short=CX3CR1;
AltName: Full=Fractalkine receptor;
Name=CX3CR1;
Bos taurus (Bovine).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
Pecora; Bovidae; Bovinae; Bos.
NCBI_TaxID=9913;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=Hereford; TISSUE=Hypothalamus;
NIH - Mammalian Gene Collection (MGC) project;
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
-!- FUNCTION: Receptor for the CX3C chemokine fractalkine (CX3CL1);
binds to CX3CL1 and mediates both its adhesive and migratory
functions. {ECO:0000250|UniProtKB:P49238}.
-!- SUBUNIT: Found in a ternary complex with CX3CL1 and ITGAV:ITGB3 or
ITGA4:ITGB1. {ECO:0000250|UniProtKB:P49238}.
-!- SUBCELLULAR LOCATION: Cell membrane
{ECO:0000250|UniProtKB:P49238}; Multi-pass membrane protein
{ECO:0000255}.
-!- PTM: This protein is not N-glycosylated which is unusual for G-
protein-coupled receptors. {ECO:0000250|UniProtKB:P35411}.
-!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
{ECO:0000255|PROSITE-ProRule:PRU00521}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; BC148890; AAI48891.1; -; mRNA.
RefSeq; NP_001096028.1; NM_001102558.2.
RefSeq; XP_010815705.1; XM_010817403.2.
UniGene; Bt.37607; -.
ProteinModelPortal; A6QNL7; -.
STRING; 9913.ENSBTAP00000003797; -.
PaxDb; A6QNL7; -.
Ensembl; ENSBTAT00000003797; ENSBTAP00000003797; ENSBTAG00000002923.
GeneID; 100124525; -.
KEGG; bta:100124525; -.
CTD; 1524; -.
VGNC; VGNC:27845; CX3CR1.
eggNOG; ENOG410IGZ8; Eukaryota.
eggNOG; ENOG41118PP; LUCA.
GeneTree; ENSGT00760000118785; -.
HOGENOM; HOG000234122; -.
InParanoid; A6QNL7; -.
KO; K04192; -.
OMA; PQFMFTK; -.
OrthoDB; EOG091G0D5U; -.
TreeFam; TF330966; -.
Reactome; R-BTA-380108; Chemokine receptors bind chemokines.
Reactome; R-BTA-418594; G alpha (i) signalling events.
Proteomes; UP000009136; Chromosome 22.
Bgee; ENSBTAG00000002923; -.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO; GO:0019960; F:C-X3-C chemokine binding; ISS:UniProtKB.
GO; GO:0016495; F:C-X3-C chemokine receptor activity; IEA:InterPro.
GO; GO:0007155; P:cell adhesion; IEA:InterPro.
GO; GO:0021795; P:cerebral cortex cell migration; IEA:Ensembl.
GO; GO:0048246; P:macrophage chemotaxis; IEA:Ensembl.
GO; GO:0002282; P:microglial cell activation involved in immune response; IEA:Ensembl.
GO; GO:0016525; P:negative regulation of angiogenesis; IEA:Ensembl.
GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
CDD; cd15186; 7tmA_CX3CR1; 1.
InterPro; IPR005387; Chemokine_CX3CR1.
InterPro; IPR000276; GPCR_Rhodpsn.
InterPro; IPR017452; GPCR_Rhodpsn_7TM.
Pfam; PF00001; 7tm_1; 1.
PRINTS; PR01562; FRACTALKINER.
PRINTS; PR00237; GPCRRHODOPSN.
PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
2: Evidence at transcript level;
Cell membrane; Complete proteome; Disulfide bond;
G-protein coupled receptor; Membrane; Phosphoprotein; Receptor;
Reference proteome; Transducer; Transmembrane; Transmembrane helix.
CHAIN 1 358 CX3C chemokine receptor 1.
/FTId=PRO_0000375805.
TOPO_DOM 1 26 Extracellular. {ECO:0000255}.
TRANSMEM 27 47 Helical; Name=1. {ECO:0000255}.
TOPO_DOM 48 68 Cytoplasmic. {ECO:0000255}.
TRANSMEM 69 89 Helical; Name=2. {ECO:0000255}.
TOPO_DOM 90 105 Extracellular. {ECO:0000255}.
TRANSMEM 106 126 Helical; Name=3. {ECO:0000255}.
TOPO_DOM 127 147 Cytoplasmic. {ECO:0000255}.
TRANSMEM 148 168 Helical; Name=4. {ECO:0000255}.
TOPO_DOM 169 186 Extracellular. {ECO:0000255}.
TRANSMEM 187 207 Helical; Name=5. {ECO:0000255}.
TOPO_DOM 208 232 Cytoplasmic. {ECO:0000255}.
TRANSMEM 233 253 Helical; Name=6. {ECO:0000255}.
TOPO_DOM 254 275 Extracellular. {ECO:0000255}.
TRANSMEM 276 296 Helical; Name=7. {ECO:0000255}.
TOPO_DOM 297 358 Cytoplasmic. {ECO:0000255}.
MOD_RES 349 349 Phosphothreonine.
{ECO:0000250|UniProtKB:Q9Z0D9}.
DISULFID 103 176 {ECO:0000255|PROSITE-ProRule:PRU00521}.
SEQUENCE 358 AA; 40849 MW; 4F18C530B1118164 CRC64;
MHTTLPESTS ENFEYYDLAE ACDMGDIVAL GTVFVVILYS LVFAFGLVGN LLVVFALINS
QRSKSITDIY LLNLALSDLL FVATLPFWTH YVINEQGLHH ATCKLITAFF FIGFFGGIFF
ITVISVDRFL AIVLAANSMS NRTVQHGVTT SLGVWAAAIL VATPQFMFTR EKENECFGDY
PEILQEIWPV ILNTEINFLG FLLPLLIMSY CYFRIMQTLF SCKNHKKAKA IRLIFLVVVV
FFLFWTPYNV MIFLQTLNLY DFFPKCDVKR DLKLAISVTE TIAFSHCCLN PLIYAFAGEK
FRRYLYRLYR KCLAVLCCHP DHLSFSSSLS ESQRSRRESV LSSNFTHYTS DGDASILL


Related products :

Catalog number Product name Quantity
U1523h CLIA Beta chemokine receptor-like 1,CMKBRL1,CMK-BRL1,CMK-BRL-1,CX3C chemokine receptor 1,C-X3-C CKR-1,CX3CR1,CX3CR1,Fractalkine receptor,GPR13,G-protein coupled receptor 13,Homo sapiens,Human,V28 96T
E1523h ELISA Beta chemokine receptor-like 1,CMKBRL1,CMK-BRL1,CMK-BRL-1,CX3C chemokine receptor 1,C-X3-C CKR-1,CX3CR1,CX3CR1,Fractalkine receptor,GPR13,G-protein coupled receptor 13,Homo sapiens,Human,V28 96T
E1523h ELISA kit Beta chemokine receptor-like 1,CMKBRL1,CMK-BRL1,CMK-BRL-1,CX3C chemokine receptor 1,C-X3-C CKR-1,CX3CR1,CX3CR1,Fractalkine receptor,GPR13,G-protein coupled receptor 13,Homo sapiens,Human,V2 96T
18-661-15051 CX3C chemokine receptor 1 - C-X3-C CKR-1; CX3CR1; Fractalkine receptor; G-protein coupled receptor 13; V28; Beta chemokine receptor-like 1; CMK-BRL-1; CMKBLR1 Polyclonal 0.1 mg
15-288-21051 CX3C chemokine receptor 1 - C-X3-C CKR-1; CX3CR1; Fractalkine receptor; G-protein coupled receptor 13; V28; Beta chemokine receptor-like 1; CMK-BRL-1; CMKBLR1 Polyclonal 0.05 mg
18-661-15074 CX3C chemokine receptor 1 - C-X3-C CKR-1; CX3CR1; Fractalkine receptor; G-protein coupled receptor 13; V28; Beta chemokine receptor-like 1; CMK-BRL-1; CMKBLR1 Polyclonal 0.1 mg
15-288-21051 CX3C chemokine receptor 1 - C-X3-C CKR-1; CX3CR1; Fractalkine receptor; G-protein coupled receptor 13; V28; Beta chemokine receptor-like 1; CMK-BRL-1; CMKBLR1 Polyclonal 0.1 mg
E1523Rb ELISA kit CX3C chemokine receptor 1,C-X3-C CKR-1,CX3CR1,CX3CR1,Fractalkine receptor,Oryctolagus cuniculus,Rabbit 96T
E1523Rb ELISA CX3C chemokine receptor 1,C-X3-C CKR-1,CX3CR1,CX3CR1,Fractalkine receptor,Oryctolagus cuniculus,Rabbit 96T
U1523Rb CLIA CX3C chemokine receptor 1,C-X3-C CKR-1,CX3CR1,CX3CR1,Fractalkine receptor,Oryctolagus cuniculus,Rabbit 96T
E1523b ELISA kit Bos taurus,Bovine,CX3C chemokine receptor 1,C-X3-C CKR-1,CX3CR1,CX3CR1,Fractalkine receptor 96T
E1523m ELISA CX3C chemokine receptor 1,C-X3-C CKR-1,CX3CR1,Cx3cr1,Fractalkine receptor,Mouse,Mus musculus 96T
E1523b ELISA Bos taurus,Bovine,CX3C chemokine receptor 1,C-X3-C CKR-1,CX3CR1,CX3CR1,Fractalkine receptor 96T
E1523m ELISA kit CX3C chemokine receptor 1,C-X3-C CKR-1,CX3CR1,Cx3cr1,Fractalkine receptor,Mouse,Mus musculus 96T
U1523b CLIA Bos taurus,Bovine,CX3C chemokine receptor 1,C-X3-C CKR-1,CX3CR1,CX3CR1,Fractalkine receptor 96T
U1523m CLIA CX3C chemokine receptor 1,C-X3-C CKR-1,CX3CR1,Cx3cr1,Fractalkine receptor,Mouse,Mus musculus 96T
E1523r ELISA CX3C chemokine receptor 1,C-X3-C CKR-1,CX3CR1,Cx3cr1,Fractalkine receptor,Rat,Rattus norvegicus,RBS11,Rbs11 96T
U1523r CLIA CX3C chemokine receptor 1,C-X3-C CKR-1,CX3CR1,Cx3cr1,Fractalkine receptor,Rat,Rattus norvegicus,RBS11,Rbs11 96T
E1523r ELISA kit CX3C chemokine receptor 1,C-X3-C CKR-1,CX3CR1,Cx3cr1,Fractalkine receptor,Rat,Rattus norvegicus,RBS11,Rbs11 96T
GWB-86D62E CX3C Chemokine Fractalkine Receptor 1 (CX3CR1) Rabbit anti-Human Polyclonal Antibody
E12410671 Rat CX3C-Chemokine Receptor 1(CX3CR1) ELISA Kit 1
CSB-EL006236RA Rat CX3C chemokine receptor 1(CX3CR1) ELISA kit 96T
CK-E95830 Human CX3C-chemokine receptor 1,CX3CR1 ELISAkit
UT-E04509 Human CX3C-Chemokine Receptor 1 (CX3CR1) ELISA Kit 96T
CSB-E09942h Human CX3C-chemokine receptor 1,CX3CR1 ELISA Kit 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur