Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Calcium homeostasis modulator protein 1 (Protein FAM26C)

 CAHM1_HUMAN             Reviewed;         346 AA.
Q8IU99; Q5W091;
05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
05-JUL-2005, sequence version 2.
25-OCT-2017, entry version 118.
RecName: Full=Calcium homeostasis modulator protein 1;
AltName: Full=Protein FAM26C;
Name=CALHM1; Synonyms=FAM26C;
Homo sapiens (Human).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
NCBI_TaxID=9606;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=15164054; DOI=10.1038/nature02462;
Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L.,
Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K.,
Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L.,
Taylor A., Battles J., Bird C.P., Ainscough R., Almeida J.P.,
Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J.,
Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J.,
Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D.,
Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S.,
Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L.,
Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S.,
Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L.,
Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J.,
Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M.,
Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S.,
Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M.,
Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A.,
Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T.,
Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I.,
Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T.,
Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M.,
Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W.,
Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H.,
Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L.,
Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K.,
Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T.,
Doucette-Stamm L., Beck S., Smith D.R., Rogers J.;
"The DNA sequence and comparative analysis of human chromosome 10.";
Nature 429:375-381(2004).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANT PRO-86.
TISSUE=Brain;
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
[3]
FUNCTION, SUBUNIT, SUBCELLULAR LOCATION, TISSUE SPECIFICITY,
GLYCOSYLATION AT ASN-140, VARIANT PRO-86, POLYMORPHISM, AND
MUTAGENESIS OF ASN-72; ASN-74 AND ASN-140.
PubMed=18585350; DOI=10.1016/j.cell.2008.05.048;
Dreses-Werringloer U., Lambert J.-C., Vingtdeux V., Zhao H., Vais H.,
Siebert A., Jain A., Koppel J., Rovelet-Lecrux A., Hannequin D.,
Pasquier F., Galimberti D., Scarpini E., Mann D., Lendon C.,
Campion D., Amouyel P., Davies P., Foskett J.K., Campagne F.,
Marambaud P.;
"A polymorphism in CALHM1 influences Ca2+ homeostasis, Abeta levels,
and Alzheimer's disease risk.";
Cell 133:1149-1161(2008).
[4]
TISSUE SPECIFICITY.
PubMed=19997627; DOI=10.1371/journal.pone.0007682;
Moyer B.D., Hevezi P., Gao N., Lu M., Kalabat D., Soto H.,
Echeverri F., Laita B., Yeh S.A., Zoller M., Zlotnik A.;
"Expression of genes encoding multi-transmembrane proteins in specific
primate taste cell populations.";
PLoS ONE 4:E7682-E7682(2009).
[5]
FUNCTION.
PubMed=21574960; DOI=10.1042/BJ20110479;
Gallego-Sandin S., Alonso M.T., Garcia-Sancho J.;
"Calcium homoeostasis modulator 1 (CALHM1) reduces the calcium content
of the endoplasmic reticulum (ER) and triggers ER stress.";
Biochem. J. 437:469-475(2011).
[6]
FUNCTION, ENZYME REGULATION, SUBCELLULAR LOCATION, AND MUTAGENESIS OF
ASN-72; ASP-121; GLU-163 AND ASP-166.
PubMed=22711817; DOI=10.1073/pnas.1204023109;
Ma Z., Siebert A.P., Cheung K.H., Lee R.J., Johnson B., Cohen A.S.,
Vingtdeux V., Marambaud P., Foskett J.K.;
"Calcium homeostasis modulator 1 (CALHM1) is the pore-forming subunit
of an ion channel that mediates extracellular Ca2+ regulation of
neuronal excitability.";
Proc. Natl. Acad. Sci. U.S.A. 109:E1963-E1971(2012).
[7]
FUNCTION, SUBUNIT, TOPOLOGY, AND SUBCELLULAR LOCATION.
PubMed=23300080; DOI=10.1074/jbc.M112.409789;
Siebert A.P., Ma Z., Grevet J.D., Demuro A., Parker I., Foskett J.K.;
"Structural and functional similarities of calcium homeostasis
modulator 1 (CALHM1) ion channel with connexins, pannexins, and
innexins.";
J. Biol. Chem. 288:6140-6153(2013).
[8]
FUNCTION, AND MUTAGENESIS OF TRP-114 AND ASN-140.
PubMed=23345406; DOI=10.1242/jcs.117135;
Dreses-Werringloer U., Vingtdeux V., Zhao H., Chandakkar P.,
Davies P., Marambaud P.;
"CALHM1 controls Ca2+-dependent MEK/ERK/RSK/MSK signaling in
neurons.";
J. Cell Sci. 126:1199-1206(2013).
[9]
VARIANT PRO-86.
PubMed=19472444; DOI=10.1111/j.1469-1809.2009.00509.x;
Beecham G.W., Schnetz-Boutaud N., Haines J.L., Pericak-Vance M.A.;
"CALHM1 polymorphism is not associated with late-onset Alzheimer
disease.";
Ann. Hum. Genet. 73:379-381(2009).
[10]
VARIANT PRO-86.
PubMed=19070563; DOI=10.1016/j.cell.2008.11.030;
Bertram L., Schjeide B.M., Hooli B., Mullin K., Hiltunen M.,
Soininen H., Ingelsson M., Lannfelt L., Blacker D., Tanzi R.E.;
"No association between CALHM1 and Alzheimer's disease risk.";
Cell 135:993-994(2008).
[11]
VARIANT PRO-86.
PubMed=19191331; DOI=10.1002/humu.20989;
Minster R.L., Demirci F.Y., DeKosky S.T., Kamboh M.I.;
"No association between CALHM1 variation and risk of Alzheimer
disease.";
Hum. Mutat. 30:E566-E569(2009).
[12]
VARIANT PRO-86.
PubMed=19191332; DOI=10.1002/humu.20990;
Sleegers K., Brouwers N., Bettens K., Engelborghs S., van Miegroet H.,
De Deyn P.P., Van Broeckhoven C.;
"No association between CALHM1 and risk for Alzheimer dementia in a
Belgian population.";
Hum. Mutat. 30:E570-E574(2009).
[13]
VARIANT PRO-86.
PubMed=19545933; DOI=10.1016/j.neurobiolaging.2009.05.008;
Tan E.K., Ho P., Cheng S.Y., Yih Y., Li H.H., Fook-Chong S., Lee W.L.,
Zhao Y.;
"CALHM1 variant is not associated with Alzheimer's disease among
Asians.";
Neurobiol. Aging 32:546.E11-546.E12(2011).
[14]
VARIANT PRO-86.
PubMed=19655363; DOI=10.1002/ajmg.b.31014;
Inoue K., Tanaka N., Yamashita F., Sawano Y., Asada T., Goto Y.;
"The P86L common allele of CALHM1 does not influence risk for
Alzheimer disease in Japanese cohorts.";
Am. J. Med. Genet. B Neuropsychiatr. Genet. 153:532-535(2010).
[15]
VARIANT PRO-86.
PubMed=20061624; DOI=10.3233/JAD-2010-1207;
Cui P.J., Zheng L., Cao L., Wang Y., Deng Y.L., Wang G., Xu W.,
Tang H.D., Ma J.F., Zhang T., Ding J.Q., Cheng Q., Chen S.D.;
"CALHM1 P86L polymorphism is a risk factor for Alzheimer's disease in
the Chinese population.";
J. Alzheimers Dis. 19:31-35(2010).
[16]
VARIANT PRO-86.
PubMed=20164592; DOI=10.3233/JAD-2010-1357;
Boada M., Antunez C., Lopez-Arrieta J., Galan J.J., Moron F.J.,
Hernandez I., Marin J., Martinez-Lage P., Alegret M., Carrasco J.M.,
Moreno C., Real L.M., Gonzalez-Perez A., Tarraga L., Ruiz A.;
"CALHM1 P86L polymorphism is associated with late-onset Alzheimer's
disease in a recessive model.";
J. Alzheimers Dis. 20:247-251(2010).
[17]
VARIANT PRO-86.
PubMed=20847397; DOI=10.3233/JAD-2010-100933;
Lambert J.C., Sleegers K., Gonzalez-Perez A., Ingelsson M.,
Beecham G.W., Hiltunen M., Combarros O., Bullido M.J., Brouwers N.,
Bettens K., Berr C., Pasquier F., Richard F., Dekosky S.T.,
Hannequin D., Haines J.L., Tognoni G., Fievet N., Dartigues J.F.,
Tzourio C., Engelborghs S., Arosio B., Coto E., De Deyn P.,
Del Zompo M., Mateo I., Boada M., Antunez C., Lopez-Arrieta J.,
Epelbaum J., Schjeide B.M., Frank-Garcia A., Giedraitis V.,
Helisalmi S., Porcellini E., Pilotto A., Forti P., Ferri R.,
Delepine M., Zelenika D., Lathrop M., Scarpini E., Siciliano G.,
Solfrizzi V., Sorbi S., Spalletta G., Ravaglia G., Valdivieso F.,
Vepsalainen S., Alvarez V., Bosco P., Mancuso M., Panza F.,
Nacmias B., Bossu P., Hanon O., Piccardi P., Annoni G., Mann D.,
Marambaud P., Seripa D., Galimberti D., Tanzi R.E., Bertram L.,
Lendon C., Lannfelt L., Licastro F., Campion D., Pericak-Vance M.A.,
Soininen H., Van Broeckhoven C., Alperovitch A., Ruiz A., Kamboh M.I.,
Amouyel P.;
"The CALHM1 P86L polymorphism is a genetic modifier of age at onset in
Alzheimer's disease: a meta-analysis study.";
J. Alzheimers Dis. 22:247-255(2010).
[18]
VARIANT PRO-86.
PubMed=21378601; DOI=10.1097/YPG.0b013e3283457bcc;
Feher A., Juhasz A., Rimanoczy A., Pakaski M., Kalman J., Janka Z.;
"No association between CALHM1 polymorphism and Alzheimer's disease
risk in a Hungarian population.";
Psychiatr. Genet. 21:249-252(2011).
-!- FUNCTION: Pore-forming subunit of a voltage-gated ion channel
required for sensory perception of sweet, bitter and umami tastes.
Specifically present in type II taste bud cells, where it plays a
central role in sweet, bitter and umami taste perception by
inducing ATP release from the cell, ATP acting as a
neurotransmitter to activate afferent neural gustatory pathways.
Acts both as a voltage-gated and calcium-activated ion channel:
mediates neuronal excitability in response to changes in
extracellular Ca(2+) concentration. Has poor ion selectivity and
forms a wide pore (around 14 Angstroms) that mediates permeation
of Ca(2+), Na(+) and K(+), as well as permeation of monovalent
anions. Acts as an activator of the ERK1 and ERK2 cascade.
Triggers endoplasmic reticulum stress by reducing the calcium
content of the endoplasmic reticulum. May indirectly control
amyloid precursor protein (APP) proteolysis and aggregated
amyloid-beta (Abeta) peptides levels in a Ca(2+) dependent manner.
{ECO:0000269|PubMed:18585350, ECO:0000269|PubMed:21574960,
ECO:0000269|PubMed:22711817, ECO:0000269|PubMed:23300080,
ECO:0000269|PubMed:23345406}.
-!- ENZYME REGULATION: Inhibited by Gd(3+), Ruthenium Red, and Zn(2+)
and partially inhibited by 2-aminoethoxydiphenyl borate.
{ECO:0000269|PubMed:22711817}.
-!- SUBUNIT: Homohexamer. {ECO:0000269|PubMed:18585350,
ECO:0000269|PubMed:23300080}.
-!- INTERACTION:
Self; NbExp=3; IntAct=EBI-1790341, EBI-1790341;
-!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Note=Colocalizes with HSPA5 at the endoplasmic reticulum.
-!- TISSUE SPECIFICITY: Predominantly expressed in adult brain.
Detected also in retinoic acid-differentiated SH-SY5Y cells.
Specifically expressed in circumvallate taste bud cells.
{ECO:0000269|PubMed:18585350, ECO:0000269|PubMed:19997627}.
-!- POLYMORPHISM: Leu-86 causes a dysregulation of Ca(2+) homeostasis
and amyloid precursor protein (APP) metabolism and has been
suggested to be a risk factor for the development of Alzheimer
disease (PubMed:18585350, PubMed:20061624, PubMed:20164592).
However, this association with Alzheimer disease could not be
confirmed in a number of studies performed in different
populations (PubMed:19472444, PubMed:19070563, PubMed:19191331,
PubMed:19191332, PubMed:19545933, PubMed:19655363,
PubMed:21378601). According to a meta-analysis study, Leu-86 is
likely not a genetic determinant of Alzheimer disease but may
modulate age of onset by interacting with the effect of the APOE*4
allele of the APOE gene (PubMed:20847397).
{ECO:0000269|PubMed:18585350, ECO:0000269|PubMed:19070563,
ECO:0000269|PubMed:19191331, ECO:0000269|PubMed:19191332,
ECO:0000269|PubMed:19472444, ECO:0000269|PubMed:19545933,
ECO:0000269|PubMed:19655363, ECO:0000269|PubMed:20061624,
ECO:0000269|PubMed:20164592, ECO:0000269|PubMed:20847397,
ECO:0000269|PubMed:21378601}.
-!- SIMILARITY: Belongs to the FAM26 family. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AL139339; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; BC036193; AAH36193.1; -; mRNA.
EMBL; BC036208; AAH36208.1; -; mRNA.
CCDS; CCDS7550.1; -.
RefSeq; NP_001001412.3; NM_001001412.3.
UniGene; Hs.680365; -.
ProteinModelPortal; Q8IU99; -.
STRING; 9606.ENSP00000329926; -.
TCDB; 1.A.84.1.1; the calcium homeostasis modulator ca(2+) channel (calhm-c) family.
iPTMnet; Q8IU99; -.
PhosphoSitePlus; Q8IU99; -.
BioMuta; CALHM1; -.
DMDM; 68565595; -.
PaxDb; Q8IU99; -.
PRIDE; Q8IU99; -.
DNASU; 255022; -.
Ensembl; ENST00000329905; ENSP00000329926; ENSG00000185933.
GeneID; 255022; -.
KEGG; hsa:255022; -.
UCSC; uc001kxe.3; human.
CTD; 255022; -.
DisGeNET; 255022; -.
EuPathDB; HostDB:ENSG00000185933.6; -.
GeneCards; CALHM1; -.
H-InvDB; HIX0201512; -.
HGNC; HGNC:23494; CALHM1.
HPA; HPA018317; -.
MIM; 612234; gene.
neXtProt; NX_Q8IU99; -.
OpenTargets; ENSG00000185933; -.
PharmGKB; PA162380954; -.
eggNOG; ENOG410IG7G; Eukaryota.
eggNOG; ENOG410YNIM; LUCA.
GeneTree; ENSGT00530000062796; -.
HOGENOM; HOG000111295; -.
HOVERGEN; HBG096020; -.
InParanoid; Q8IU99; -.
KO; K19738; -.
OMA; VMNNNVS; -.
OrthoDB; EOG091G09L8; -.
PhylomeDB; Q8IU99; -.
TreeFam; TF329085; -.
GenomeRNAi; 255022; -.
PRO; PR:Q8IU99; -.
Proteomes; UP000005640; Chromosome 10.
Bgee; ENSG00000185933; -.
CleanEx; HS_CALHM1; -.
Genevisible; Q8IU99; HS.
GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO; GO:0005887; C:integral component of plasma membrane; IDA:UniProtKB.
GO; GO:0005227; F:calcium activated cation channel activity; IDA:UniProtKB.
GO; GO:0042802; F:identical protein binding; IPI:IntAct.
GO; GO:0005245; F:voltage-gated calcium channel activity; IEA:Ensembl.
GO; GO:0005244; F:voltage-gated ion channel activity; IDA:UniProtKB.
GO; GO:0015867; P:ATP transport; ISS:UniProtKB.
GO; GO:0006812; P:cation transport; IDA:UniProtKB.
GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
GO; GO:0034765; P:regulation of ion transmembrane transport; IDA:UniProtKB.
GO; GO:0050913; P:sensory perception of bitter taste; ISS:UniProtKB.
GO; GO:0050916; P:sensory perception of sweet taste; ISS:UniProtKB.
GO; GO:0050917; P:sensory perception of umami taste; ISS:UniProtKB.
InterPro; IPR029568; CALHM1.
InterPro; IPR029569; FAM26.
PANTHER; PTHR32261; PTHR32261; 1.
PANTHER; PTHR32261:SF2; PTHR32261:SF2; 1.
Pfam; PF14798; Ca_hom_mod; 1.
1: Evidence at protein level;
Calcium; Calcium channel; Calcium transport; Cell membrane;
Complete proteome; Endoplasmic reticulum; Glycoprotein; Ion channel;
Ion transport; Membrane; Polymorphism; Reference proteome;
Transmembrane; Transmembrane helix; Transport.
CHAIN 1 346 Calcium homeostasis modulator protein 1.
/FTId=PRO_0000186723.
TOPO_DOM 1 17 Cytoplasmic. {ECO:0000255}.
TRANSMEM 18 38 Helical. {ECO:0000255}.
TOPO_DOM 39 50 Extracellular. {ECO:0000255}.
TRANSMEM 51 71 Helical. {ECO:0000255}.
TOPO_DOM 72 108 Cytoplasmic. {ECO:0000255}.
TRANSMEM 109 129 Helical. {ECO:0000255}.
TOPO_DOM 130 181 Extracellular. {ECO:0000255}.
TRANSMEM 182 202 Helical. {ECO:0000255}.
TOPO_DOM 203 346 Cytoplasmic. {ECO:0000255}.
SITE 74 74 Not glycosylated.
CARBOHYD 140 140 N-linked (GlcNAc...) asparagine.
{ECO:0000269|PubMed:18585350}.
VARIANT 86 86 L -> P (in dbSNP:rs2986017).
{ECO:0000269|PubMed:15489334,
ECO:0000269|PubMed:18585350,
ECO:0000269|PubMed:19070563,
ECO:0000269|PubMed:19191331,
ECO:0000269|PubMed:19191332,
ECO:0000269|PubMed:19472444,
ECO:0000269|PubMed:19545933,
ECO:0000269|PubMed:19655363,
ECO:0000269|PubMed:20061624,
ECO:0000269|PubMed:20164592,
ECO:0000269|PubMed:20847397,
ECO:0000269|PubMed:21378601}.
/FTId=VAR_023095.
MUTAGEN 72 72 N->G: Significant inhibition on the
control of cytosolic Ca(2+) levels. Does
not affect ion channel activity.
{ECO:0000269|PubMed:18585350,
ECO:0000269|PubMed:22711817}.
MUTAGEN 74 74 N->A: Has no effect on glycosylation.
{ECO:0000269|PubMed:18585350}.
MUTAGEN 114 114 W->A: Impairs ability to activate the
ERK1 and ERK2 cascade.
{ECO:0000269|PubMed:23345406}.
MUTAGEN 121 121 D->C: Impaired ion channel activity in
response to change in extracellular
Ca(2+) concentration.
{ECO:0000269|PubMed:22711817}.
MUTAGEN 121 121 D->E: No effect.
{ECO:0000269|PubMed:22711817}.
MUTAGEN 140 140 N->A: Prevents glycosylation and impairs
ability to activate the ERK1 and ERK2
cascade. {ECO:0000269|PubMed:18585350,
ECO:0000269|PubMed:23345406}.
MUTAGEN 163 163 E->A: No effect.
{ECO:0000269|PubMed:22711817}.
MUTAGEN 166 166 D->R: No effect.
{ECO:0000269|PubMed:22711817}.
CONFLICT 264 264 H -> N (in Ref. 2; AAH36193/AAH36208).
{ECO:0000305}.
SEQUENCE 346 AA; 38264 MW; 13A1FBA6592A9EC1 CRC64;
MMDKFRMIFQ FLQSNQESFM NGICGIMALA SAQMYSAFDF NCPCLPGYNA AYSAGILLAP
PLVLFLLGLV MNNNVSMLAE EWKRPLGRRA KDPAVLRYMF CSMAQRALIA PVVWVAVTLL
DGKCFLCAFC TAVPVSALGN GSLAPGLPAP ELARLLARVP CPEIYDGDWL LAREVAVRYL
RCISQALGWS FVLLTTLLAF VVRSVRPCFT QAAFLKSKYW SHYIDIERKL FDETCTEHAK
AFAKVCIQQF FEAMNHDLEL GHTHGTLATA PASAAAPTTP DGAEEEREKL RGITDQGTMN
RLLTSWHKCK PPLRLGQEEP PLMGNGWAGG GPRPPRKEVA TYFSKV


Related products :

Catalog number Product name Quantity
EIAAB05187 Calcium homeostasis modulator protein 1,CALHM1,FAM26C,Homo sapiens,Human,Protein FAM26C
EIAAB05191 Bos taurus,Bovine,Calcium homeostasis modulator protein 2,CALHM2,Protein FAM26B
orb109436 Calcium Homeostasis Modulator Protein 1 antibody 100 ug
orb109550 Calcium Homeostasis Modulator Protein 1 antibody 10 Miniblots
CAHM1_MOUSE Mouse ELISA Kit FOR Calcium homeostasis modulator protein 1 96T
CAHM3_HUMAN Human ELISA Kit FOR Calcium homeostasis modulator protein 3 96T
CSB-EL004443RA Rat Calcium homeostasis modulator protein 2(CALHM2) ELISA kit 96T
CSB-EL004443MO Mouse Calcium homeostasis modulator protein 2(CALHM2) ELISA kit 96T
CSB-EL004443BO Bovine Calcium homeostasis modulator protein 2(CALHM2) ELISA kit 96T
CSB-EL004443RA Rat Calcium homeostasis modulator protein 2(CALHM2) ELISA kit SpeciesRat 96T
X2410P Human Calcium Homeostasis Modulator Protein 1 Polyclonal Antibody 100
CSB-EL004444HU Human Calcium homeostasis modulator protein 3(CALHM3) ELISA kit 96T
CSB-EL004443HU Human Calcium homeostasis modulator protein 2(CALHM2) ELISA kit 96T
CSB-EL004442HU Human Calcium homeostasis modulator protein 1(CALHM1) ELISA kit 96T
CSB-EL004443BO Bovine Calcium homeostasis modulator protein 2(CALHM2) ELISA kit SpeciesBovine 96T
CSB-EL004443HU Human Calcium homeostasis modulator protein 2(CALHM2) ELISA kit SpeciesHuman 96T
CSB-EL004442HU Human Calcium homeostasis modulator protein 1(CALHM1) ELISA kit SpeciesHuman 96T
CSB-EL004444HU Human Calcium homeostasis modulator protein 3(CALHM3) ELISA kit SpeciesHuman 96T
CSB-EL004443MO Mouse Calcium homeostasis modulator protein 2(CALHM2) ELISA kit SpeciesMouse 96T
X2723P Human Calcium Homeostasis Modulator Protein 1 Antigen Immunoaffinity Purified Polyclonal 10 Miniblots
CAHM3_HUMAN ELISA Kit FOR Calcium homeostasis modulator protein 3; organism: Human; gene name: CALHM3 96T
CAHM2_BOVIN ELISA Kit FOR Calcium homeostasis modulator protein 2; organism: Bovine; gene name: CALHM2 96T
CAHM2_HUMAN ELISA Kit FOR Calcium homeostasis modulator protein 2; organism: Human; gene name: CALHM2 96T
CAHM2_MOUSE ELISA Kit FOR Calcium homeostasis modulator protein 2; organism: Mouse; gene name: Calhm2 96T
CAHM1_HUMAN ELISA Kit FOR Calcium homeostasis modulator protein 1; organism: Human; gene name: CALHM1 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur