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Caprin family member 2

 G1TEH1_RABIT            Unreviewed;      1044 AA.
G1TEH1;
19-OCT-2011, integrated into UniProtKB/TrEMBL.
13-NOV-2013, sequence version 2.
28-MAR-2018, entry version 41.
SubName: Full=Caprin family member 2 {ECO:0000313|Ensembl:ENSOCUP00000015296};
Name=CAPRIN2 {ECO:0000313|Ensembl:ENSOCUP00000015296};
Oryctolagus cuniculus (Rabbit).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae;
Oryctolagus.
NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000015296, ECO:0000313|Proteomes:UP000001811};
[1] {ECO:0000313|Ensembl:ENSOCUP00000015296, ECO:0000313|Proteomes:UP000001811}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Thorbecke {ECO:0000313|Proteomes:UP000001811};
PubMed=21993624; DOI=10.1038/nature10530;
Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J.,
Washietl S., Kheradpour P., Ernst J., Jordan G., Mauceli E.,
Ward L.D., Lowe C.B., Holloway A.K., Clamp M., Gnerre S., Alfoldi J.,
Beal K., Chang J., Clawson H., Cuff J., Di Palma F., Fitzgerald S.,
Flicek P., Guttman M., Hubisz M.J., Jaffe D.B., Jungreis I.,
Kent W.J., Kostka D., Lara M., Martins A.L., Massingham T., Moltke I.,
Raney B.J., Rasmussen M.D., Robinson J., Stark A., Vilella A.J.,
Wen J., Xie X., Zody M.C., Baldwin J., Bloom T., Chin C.W., Heiman D.,
Nicol R., Nusbaum C., Young S., Wilkinson J., Worley K.C., Kovar C.L.,
Muzny D.M., Gibbs R.A., Cree A., Dihn H.H., Fowler G., Jhangiani S.,
Joshi V., Lee S., Lewis L.R., Nazareth L.V., Okwuonu G.,
Santibanez J., Warren W.C., Mardis E.R., Weinstock G.M., Wilson R.K.,
Delehaunty K., Dooling D., Fronik C., Fulton L., Fulton B., Graves T.,
Minx P., Sodergren E., Birney E., Margulies E.H., Herrero J.,
Green E.D., Haussler D., Siepel A., Goldman N., Pollard K.S.,
Pedersen J.S., Lander E.S., Kellis M.;
"A high-resolution map of human evolutionary constraint using 29
mammals.";
Nature 478:476-482(2011).
[2] {ECO:0000313|Ensembl:ENSOCUP00000015296}
IDENTIFICATION.
STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000015296};
Ensembl;
Submitted (SEP-2011) to UniProtKB.
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EMBL; AAGW02045126; -; NOT_ANNOTATED_CDS; Genomic_DNA.
RefSeq; XP_008257664.1; XM_008259442.2.
STRING; 9986.ENSOCUP00000015296; -.
Ensembl; ENSOCUT00000017809; ENSOCUP00000015296; ENSOCUG00000017805.
GeneID; 100351407; -.
CTD; 65981; -.
eggNOG; ENOG410IEA8; Eukaryota.
eggNOG; ENOG4110M5Q; LUCA.
GeneTree; ENSGT00760000119052; -.
InParanoid; G1TEH1; -.
OMA; YFWDLLE; -.
OrthoDB; EOG091G0UOF; -.
TreeFam; TF329471; -.
Proteomes; UP000001811; Chromosome 8.
Bgee; ENSOCUG00000017805; -.
GO; GO:0005813; C:centrosome; IEA:Ensembl.
GO; GO:0005829; C:cytosol; IEA:Ensembl.
GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
GO; GO:0005634; C:nucleus; IEA:Ensembl.
GO; GO:0043235; C:receptor complex; IEA:Ensembl.
GO; GO:0005102; F:receptor binding; IEA:Ensembl.
GO; GO:0030308; P:negative regulation of cell growth; IEA:Ensembl.
GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IEA:Ensembl.
GO; GO:0061003; P:positive regulation of dendritic spine morphogenesis; IEA:Ensembl.
GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IEA:Ensembl.
GO; GO:0032092; P:positive regulation of protein binding; IEA:Ensembl.
GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:Ensembl.
Gene3D; 2.60.120.40; -; 1.
InterPro; IPR001073; C1q_dom.
InterPro; IPR028816; Caprin.
InterPro; IPR022070; Caprin-1_C.
InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
PANTHER; PTHR22922; PTHR22922; 1.
Pfam; PF00386; C1q; 1.
Pfam; PF12287; Caprin-1_C; 1.
PRINTS; PR00007; COMPLEMNTC1Q.
SMART; SM00110; C1Q; 1.
SUPFAM; SSF49842; SSF49842; 1.
PROSITE; PS50871; C1Q; 1.
4: Predicted;
Coiled coil {ECO:0000256|SAM:Coils};
Complete proteome {ECO:0000313|Proteomes:UP000001811};
Reference proteome {ECO:0000313|Proteomes:UP000001811}.
DOMAIN 910 1044 C1q. {ECO:0000259|PROSITE:PS50871}.
COILED 72 99 {ECO:0000256|SAM:Coils}.
COILED 120 140 {ECO:0000256|SAM:Coils}.
SEQUENCE 1044 AA; 115458 MW; CA7ACF5F86595ECC CRC64;
MVQLSSSAFG YQTPSGLAEE GTVANMKAAK PQLNHSPHGE GPRAMSPLQP TVSSASPSQA
YETYIDNGLI CLKHKIRNIE KKKLKLEDYK DRLKNGEQLN PDQLEAVEKY EEVLHNLEFA
KELQKTFSGL SQDLLKAQKK AQRREHLIKL EAEKKKLRTI LQVQYVLQNL TQEHVQKDFR
GGLNGAVYLP SKELDYLIKF SKLTCPERNE SLSVEDQMEQ SSLYFWDLLE GSEKAVVGTT
YKHMKDLLSK LLNSGYFESI PVPKNAKEKE VSLEEELLIQ SEKKKQLLKT EPVKESESLM
ELAQPEIQPR EFLNRRYMAE VDYSGKQEEE QSWEADYARK PNLPKCWDVL TEPDGQEKKQ
ESFKSWESPK HQELSKPVVS SEPRKQEAPK LRSSLQDELK KPGVSKAKAA PSQGKQEVPK
ARAGCAQEEQ KKQETPKPWP GQLQKEQDPK KQPPKSWMPS VQSEQNLSKS WSPAVCEDQG
SKPLEPPKTW ENGVESQKHS STPQAQTSPK SWGAAAASLV PNEQLLPRKF NTEPKDVPNP
MHQPIGSSSA LPKDPALRKE KLQDLMTQIQ GTCNFMQESV LDFDKPSSAI PSSQPPSTAP
GSPGASTEQN LSSQSDFLQE PLQAASPGTR STNAGLVTAD QVSSGSEAEF MTSETPEAAV
TASKRPSSPA VPMAKGSEQG FQSPPASSSS VTINTAPFQA LQTVFNVNAP LPPRKEQEMK
ESAYSAGYNQ SFTTASTQTP PQCQLPAIHV EQTVLSQETA QTSVFPRPAQ PFVGSRGSVR
GCARGGRLLA NSYRSPGGYK GFDAYRGPPS ISNGNYSQLQ FQGRDYPGTP YSQRDNFQQC
YKRGGASGGP RTNSRAGWSD SSQVSSPERD NETFNSGDSG QGDSRSMTPV DVPVTNPAAT
ILPVHVYPLP QQMRVAFSAA RTSNLAPGTL DQPIVFDLLL NNLGETFDLQ LGRFNCPVNG
TYVFIFHMLK LAVNVPLYVN LMKNEEVLVS AYANDGAPDH ETASNHAILQ LFQGDQIWLR
LHRGAIYGSS WKYSTFSGYL LYQD


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